2701 results about "Cornea" patented technology

Methods and devices are described that are needed to design and fabricate modified surfaces on contact lenses or on corneal tissue that correct the eye's optical aberrations beyond defocus and astigmatism. The invention provides the means for: 1) measuring the eye's optical aberrations either with or without a contact lens in place on the cornea, 2) performing a mathematical analysis on the eye's optical aberrations in order to design a modified surface shape for the original contact lens or cornea that will correct the optical aberrations, 3) fabricating the aberration-correcting surface on a contact lens by diamond point turning, three dimensional contour cutting, laser ablation, thermal molding, photolithography, thin film deposition, or surface chemistry alteration, and 4) fabricating the aberration-correcting surface on a cornea by laser ablation.

The invention, exemplified as a single lens stereo optics design with a stepped mirror system for tracking the eye, isolates landmark features in the separate images, locates the pupil in the eye, matches landmarks to a template centered on the pupil, mathematically traces refracted rays back from the matched image points through the cornea to the inner structure, and locates these structures from the intersection of the rays for the separate stereo views. Having located in this way structures of the eye in the coordinate system of the optical unit, the invention computes the optical axes and from that the line of sight and the torsion roll in vision. Along with providing a wider field of view, this invention has an additional advantage since the stereo images tend to be offset from each other and for this reason the reconstructed pupil is more accurately aligned and centered.

Methods and systems for tracking a position and torsional orientation of a patient's eye. In one embodiment, the present invention provides methods and software for registering a first image of an eye with a second image of an eye. In another embodiment, the present invention provides methods and software for tracking a torsional movement of the eye. In a particular usage, the present invention tracks the torsional cyclorotation and translational movement of a patient's eye so as to improve the delivery of a laser energy to the patient's cornea.

The present invention relates to a new method for repairing human or animal tissues such as cartilage, meniscus, ligament, tendon, bone, skin, cornea, periodontal tissues, abscesses, resected tumors, and ulcers. The method comprises the step of introducing into the tissue a temperature-dependent polymer gel composition such that the composition adhere to the tissue and promote support for cell proliferation for repairing the tissue. Other than a polymer, the composition preferably comprises a blood component such as whole blood, processed blood, venous blood, arterial blood, blood from bone, blood from bone-marrow, bone marrow, umbilical cord blood, placenta blood, erythrocytes, leukocytes, monocytes, platelets, fibrinogen, thrombin and platelet rich plasma. The present invention also relates to a new composition to be used with the method of the present invention.

A method of computer-aided contact lens design and fabrication uses spline-based mathematical surfaces without restrictions of rotational symmetry. The spline encompasses any piecewise function with any associated constraints of smoothness or continuity. The method comprises some or all of the following steps: data acquisition, three-dimensional mathematical surface model construction, posterior surface description, ray tracing for anterior surface, and peripheral edge system (PES) design. The result is a mathematical or algorithmic description of a contact lens. Based on the more powerful mathematical representation of splines, these contact lenses can have posterior surfaces that provide a good fit to corneas having complicated shapes. This enables the design and fabrication of lenses (including soft lenses) with good optics for irregularly shaped corneas.

A method for applanating an anterior surface of a cornea and coupling the eye to a surgical laser is disclosed. A interface is provided which has a central orifice and top and bottom surfaces. A suction ring is removably coupled to the bottom surface of the interface. The interface is positioned over an operative area of an eye, such that the suction ring comes into proximate contact with the surface of the eye. A suction is applied to the suction ring to stabilize the position of the interface relative to the operative area of the eye. An applanation lens is positioned in proximate contact with the operative area of the eye. Finally, the applanation lens is coupled to the interface to stabilize the position of the lens relative to the operative area of the eye.

A Custom Eyeglass Manufacturing Method includes a wavefront measuring device with a plurality of cameras directed at a patient's face. The resulting images are processed by a computer to determine the location of pupils, center of pupils, pupil distance, width of face, ear location, distance of corneal apex from the wavefront measuring device, distance from ear to corneal apex, and other desired parameters necessary to quantify a patient's face for custom eyeglass fittings. Moldings may be applied to patient's nose, temples, and ears in order to construct a pair of eyeglasses that fix perfectly on patient's head. Additionally, a test frame may be used in combination with the wavefront measuring device in order to allow computer to find some of the areas automatically. Lastly, registration markers may be applied to either the test frame, the moldings, or both in order to further aide the computer in locating desired parameters.

A method for enhancing vision of an eye includes a laser delivery system having a laser beam for ablating corneal material from the cornea of the eye. Measurements are made to determine an optical path difference between a plane wave and a wavefront emanating from the retina of the eye for a location at a surface of the cornea. An optical correction is provided to the laser delivery system for the location based on the optical path difference and refractive indices of media through which the wavefront passes. The optical correction includes dividing the optical path difference by a difference between an index of refraction of corneal material and an index of refraction of air. The laser beam is directed to the location on the surface of the cornea and corneal material ablated at the location in response to the optical correction to cause the wavefront to approximate the shape of the plane wave at that location.

An ophthalmic lens suited for extended-wear periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of a oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.

Methods and devices are provided for administering a drug to a patient's eye. The methods include (a) inserting a hollow microneedle into the sclera or corneal stroma without penetrating across the sclera or corneal stroma; and (b) infusing a fluid drug formulation through the microneedle and into the sclera or cornea. It further may include partially retracting the microneedle before infusion to enhance delivery. Alternatively, the methods may include (a) inserting a solid microneedle into the sclera or corneal stroma without penetrating across the sclera or corneal stroma, wherein the solid microneedle comprises a first quantity of a drug formulation and inserting causes the solid microneedle to form a pocket in the sclera or corneal stroma; and (b) releasing the drug formulation into the pocket to form a drug depot, whereby a drug is released from the depot. The methods and devices may include an array of multiple microneedles.

An lens for correcting human vision, for example an IOL, contact lens or corneal inlay or onlay, that carries and interior phase or layer comprising a pattern of individual transparent adaptive displacement structures. In the exemplary embodiments, the displacement structures are actuated by shape change polymer that adjusts a shape or other parameter in response to applied energy that in turn displaces a fluid media within the lens that actuates a flexible lens surface. The adaptive optic means of the invention can be used to create highly localized surface corrections in the lens to correct higher order aberrations-which types of surfaces cannot be fabricated into and IOL and then implanted. The system of displacement structures also can provide spherical corrections in the lens.

The present invention relates to an inlay for correcting refractive error in an eye. The inlay includes a first portion having a first volume that remains substantially constant when exposed to an energy, and a second portion having a second volume that is adapted to change when exposed to the energy. This inlay results in a device that can correct severe ametropic conditions, without ablating any portion of the inlay itself or the cornea.

A foldable intraocular lens is stored in its normal unfolded configuration within a lens storage chamber in a lens insertion instrument. The instrument includes a ram which is movable inwardly through the chamber to move the lens into and fold the lens to a compact folded configuration within a bore extending through a tubular portion of the instrument terminating in a slender tip for insertion into a patient's eye through a corneal incision in the eye and through which the folded lens is ejected into the eye by a plunger movable through the bore. An ophthalmic lens insertion kit and lens insertion package including the lens insertion instrument is disclosed.

Utilization of a contact device placed on the eye in order to detect physical and chemical parameters of the body as well as the non-invasive delivery of compounds according to these physical and chemical parameters, with signals being transmitted continuously as electromagnetic waves, radio waves, infrared and the like. One of the parameters to be detected includes non-invasive blood analysis utilizing chemical changes and chemical products that are found in the conjunctiva and in the tear film. A transensor mounted in the contact device laying on the cornea or the surface of the eye is capable of evaluating and measuring physical and chemical parameters in the eye including non-invasive blood analysis. The system utilizes eye lid motion and / or closure of the eye lid to activate a microminiature radio frequency sensitive transensor mounted in the contact device. The signal can be communicated by wires or radio telemetered to an externally placed receiver. The signal can then be processed, analyzed and stored. Several parameters can be detected including a complete non-invasive analysis of blood components, measurement of systemic and ocular blood flow, measurement of heart rate and respiratory rate, tracking operations, detection of ovulation, detection of radiation and drug effects, diagnosis of ocular and systemic disorders and the like.

Optical devices having a dynamic aperture and / or an apodization mask are provided. The aperture and / or mask may be provided by one or more electro-active elements, and may be used in an ophthalmic device that that is spaced apart from but in optical communication with an intraocular lens, a corneal inlay, a corneal onlay, or a spectacle lens that provide an optical power.

An intraocular lens for correcting or reducing the astigmatism of a cornea includes an optical element that has optical properties and characteristics that make it tolerant of rotational misalignment, when compared to a comparable lens having a uniform astigmatism orientation across its entire optical element, leading to more relaxed tolerances for a surgeon that implants the lens. The optical element of the toric ophthalmic lens has meridians associated therewith, including a high power meridian and a low power meridian orthogonal to the high power meridian. The optical element has at least one radially modulated meridian along which power monotonically varies with increasing radial position.