9062results about "Eye diagnostics" patented technology

Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.

Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.

Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.

Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.

Systems and methods are disclosed for displaying data on a head's-up display screen. Multiple forms of data can be selectively displayed on a semi-transparent screen mounted in the user's normal field of view. The screen can either be mounted on the user's head, or mounted on a moveable implement and positioned in front of the user. A user interface is displayed on the screen including a moveable cursor and a menu of computer control icons. An eye-tracking system is mounted proximate the user and is employed to control movement of the cursor. By moving and focusing his or her eyes on a specific icon, the user controls the cursor to move to select the icon. When an icon is selected, a command computer is controlled to acquire and display data on the screen. The data is typically superimposed over the user's normal field of view.

Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.

This invention relates to methods and apparatus for improving communications between humans and devices. The invention provides a method of modulating operation of a device, comprising providing an attentive user interface for obtaining information about an attentive state of a user; and modulating operation of a device on the basis of the obtained information, wherein the operation that is modulated is initiated by the device. Preferably, the information about the user's attentive state is eye contact of the user with the device that is sensed by the attentive user interface.

The present invention relates to advanced signal processing methods including digital wavelet transformation to analyze heart-related electronic signals and extract features that can accurately identify various states of the cardiovascular system. The invention may be utilized to estimate the extent of blood volume loss, distinguish blood volume loss from physiological activities associated with exercise, and predict the presence and extent of cardiovascular disease in general.

The invention relates to a system and method for determining human emotion by analyzing a combination of eye properties of a user including, for example, pupil size, blink properties, eye position (or gaze) properties, or other properties. The system and method may be configured to measure the emotional impact of various stimuli presented to users by analyzing, among other data, the eye properties of the users while perceiving the stimuli. Measured eye properties may be used to distinguish between positive emotional responses (e.g., pleasant or “like”), neutral emotional responses, and negative emotional responses (e.g., unpleasant or “dislike”), as well as to determine the intensity of emotional responses.

Systems and methods for creating fully custom products from scratch without exclusive use of off-the-shelf or pre-specified components. A system for creating custom products includes an image capture device for capturing image data and / or measurement data of a user. A computer is communicatively coupled with the image capture device and configured to construct an anatomic model of the user based on the captured image data and / or measurement data. The computer provides a configurable product model and enables preview and automatic or user-guided customization of the product model. A display is communicatively coupled with the computer and displays the custom product model superimposed on the anatomic model or image data of the user. The computer is further configured to provide the customized product model to a manufacturer for manufacturing eyewear for the user in accordance with the customized product model. The manufacturing system is configured to interpret the product model and prepare instructions and control equipment for the manufacturing of the customized product.

The present invention relates to improved ophthalmic diagnostic measurement or treatment methods or devices, that make use of a combination of a high speed eye tracking device, measuring fast translation or saccadic motion of the eye, and an eye position measurement device, determining multiple dimensions of eye position or other components of eye, relative to an ophthalmic diagnostic or treatment instrument.

A method of determining an eye gaze direction of an observer is disclosed comprising the steps of: (a) capturing at least one image of the observer and determining a head pose angle of the observer; (b) utilizing the head pose angle to locate an expected eye position of the observer, and (c) analyzing the expected eye position to locate at least one eye of the observer and observing the location of the eye to determine the gaze direction.

A system and method for eye gaze tracking in human or animal subjects without calibration of cameras, specific measurements of eye geometries or the tracking of a cursor image on a screen by the subject through a known trajectory. The preferred embodiment includes one uncalibrated camera for acquiring video images of the subject's eye(s) and optionally having an on-axis illuminator, and a surface, object, or visual scene with embedded off-axis illuminator markers. The off-axis markers are reflected on the corneal surface of the subject's eyes as glints. The glints indicate the distance between the point of gaze in the surface, object, or visual scene and the corresponding marker on the surface, object, or visual scene. The marker that causes a glint to appear in the center of the subject's pupil is determined to be located on the line of regard of the subject's eye, and to intersect with the point of gaze. Point of gaze on the surface, object, or visual scene is calculated as follows. First, by determining which marker glints, as provided by the corneal reflections of the markers, are closest to the center of the pupil in either or both of the subject's eyes. This subset of glints forms a region of interest (ROI). Second, by determining the gaze vector (relative angular or Cartesian distance to the pupil center) for each of the glints in the ROI. Third, by relating each glint in the ROI to the location or identification (ID) of a corresponding marker on the surface, object, or visual scene observed by the eyes. Fourth, by interpolating the known locations of each these markers on the surface, object, or visual scene, according to the relative angular distance of their corresponding glints to the pupil center.

The invention is a system and method for determining visual attention, and supports the eye tracking measurements with other physiological signal measurements like emotions. The system and method of the invention is capable of registering stimulus related emotions from eye-tracking data. An eye tracking device of the system and other sensors collect eye properties and / or other physiological properties which allows a subject's emotional and visual attention to be observed and analyzed in relation to stimuli.

The present invention is a system and method for detecting facial features of humans in a continuous video and superimposing virtual objects onto the features automatically and dynamically in real-time. The suggested system is named Facial Enhancement Technology (FET). The FET system consists of three major modules, initialization module, facial feature detection module, and superimposition module. Each module requires demanding processing time and resources by nature, but the FET system integrates these modules in such a way that real time processing is possible. The users can interact with the system and select the objects on the screen. The superimposed image moves along with the user's random motion dynamically. The FET system enables the user to experience something that was not possible before by augmenting the person's facial images. The hardware of the FET system comprises the continuous image-capturing device, image processing and controlling system, and output display system.

A system and method for eye gaze tracking in human or animal subjects without calibration of cameras, specific measurements of eye geometries or the tracking of a cursor image on a screen by the subject through a known trajectory. The preferred embodiment includes one uncalibrated camera for acquiring video images of the subject's eye(s) and optionally having an on-axis illuminator, and a surface, object, or visual scene with embedded off-axis illuminator markers. The off-axis markers are reflected on the corneal surface of the subject's eyes as glints. The glints indicate the distance between the point of gaze in the surface, object, or visual scene and the corresponding marker on the surface, object, or visual scene. The marker that causes a glint to appear in the center of the subject's pupil is determined to be located on the line of regard of the subject's eye, and to intersect with the point of gaze. Point of gaze on the surface, object, or visual scene is calculated as follows. First, by determining which marker glints, as provided by the corneal reflections of the markers, are closest to the center of the pupil in either or both of the subject's eyes. This subset of glints forms a region of interest (ROI). Second, by determining the gaze vector (relative angular or cartesian distance to the pupil center) for each of the glints in the ROI. Third, by relating each glint in the ROI to the location or identification (ID) of a corresponding marker on the surface, object, or visual scene observed by the eyes. Fourth, by interpolating the known locations of each these markers on the surface, object, or visual scene, according to the relative angular distance of their corresponding glints to the pupil center.

A digital computer and method for processing data indicative of images of facial and head movements of a subject to recognize at least one of said movements and to determine at least one mental state of said subject is provided. The outputting instructions for providing to a user information relating to at least one said mental state. A further processing data reflective of input from a user, and based at least in part on said input, confirming or modifying said determination and generating with a transducer an output of humanly perceptible stimuli indicative of said at least one mental state.

The noninvasive measurement system provides a technique for manipulating wave data. In particular, wave data reflected from a biological entity is received, and the reflected wave data is correlated to a substance in the biological entity. The wave data may comprise light waves, and the biological entity may comprise a human being or blood. Additionally, a substance may comprise, for example, a molecule or ionic substance. The molecule may be, for example, a glucose molecule.Furthermore, the wave data is used to form a matrix of pixels with the received wave data. The matrix of pixels may be modified by techniques of masking, stretching, or removing hot spots.Then, the pixels may be integrated to obtain an integration value that is correlated to a glucose level. The correlation process may use a lookup table, which may be calibrated to a particular biological entity. Moreover, an amplitude and phase angle may be calculated for the reflected wave data and used to identify a glucose level in the biological entity.The glucose level may be displayed on a monitor attached to the computer. The computer may be a portable, self-contained unit that comprises a data processing system and a wave reflection capture system. On the other hand, the computer may be attached to a network of other computers, wherein the reflected wave data is received by the computer and forwarded to another computer in the network for processing.

A method of designing a multifocal ophthalmic lens with one base focus and at least one additional focus, capable of reducing aberrations of the eye for at least one of the foci after its implantation, comprising the steps of: (i) characterizing at least one corneal surface as a mathematical model; (ii) calculating the resulting aberrations of said corneal surface(s) by employing said mathematical model; (iii) modelling the multifocal ophthalmic lens such that a wavefront arriving from an optical system comprising said lens and said at least one corneal surface obtains reduced aberrations for at least one of the foci. There is also disclosed a method of selecting a multifocal intraocular lens, a method of designing a multifocal ophthalmic lens based on corneal data from a group of patients, and a multifocal ophthalmic lens.

The invention describes several embodiments of an adapter which can make use of the devices in any commercially available digital cameras to accomplish different functions, such as a fundus camera, as a microscope or as an en-face optical coherence tomography (OCT) to produce constant depth OCT images or as a Fourier domain (channelled spectrum) optical coherence tomography to produce a reflectivity profile in the depth of an object or cross section OCT images, or depth resolved volumes. The invention admits addition of confocal detection and provides simultaneous measurements or imaging in at least two channels, confocal and OCT, where the confocal channel provides an en-face image simultaneous with the acquisition of OCT cross sections, to guide the acquisition as well as to be used subsequently in the visualisation of OCT images. Different technical solutions are provided for the assembly of one or two digital cameras which together with such adapters lead to modular and portable high resolution imaging systems which can accomplish various functions with a minimum of extra components while adapting the elements in the digital camera. The cost of such adapters is comparable with that of commercial digital cameras, i.e. the total cost of such assemblies of commercially digital cameras and dedicated adapters to accomplish high resolution imaging are at a fraction of the cost of dedicated stand alone instruments. Embodiments and methods are presented to employ colour cameras and their associated optical sources to deliver simultaneous signals using their colour sensor parts to provide spectroscopic information, phase shifting inferometry in one step, depth range extension, polarisation, angular measurements and spectroscopic Fourier domain (channelled spectrum) optical coherence tomography in as many spectral bands simultaneously as the number of colour parts of the photodetector sensor in the digital camera. In conjunction with simultaneous acquistion of a confocal image, at least 4 channels can simultaneously be provided using the three color parts of conventional color cameras to deliver three OCT images in addition to the confocal image.

In some embodiments, a first device may be provided. The first device may include a first lens that comprises a contact lens or an intraocular lens. The first lens may include an electronic component and a dynamic optic, where the dynamic optic is configured to provide a first optical add power and a second optical add power, where the first and the second optical add powers are different. The dynamic optic may comprise a fluid lens.

A system is provided for identifying reference locations within the environment of a device wearer. The system includes a scene camera mounted on eyewear or headwear coupled to a processing unit. The system may recognize objects with known geometries that occur naturally within the wearer's environment or objects that have been intentionally placed at known locations within the wearer's environment. One or more light sources may be mounted on the headwear that illuminate reflective surfaces at selected times and wavelengths to help identify scene reference locations and glints projected from known locations onto the surface of the eye. The processing unit may control light sources to adjust illumination levels in order to help identify reference locations within the environment and corresponding glints on the surface of the eye. Objects may be identified substantially continuously within video images from scene cameras to provide a continuous data stream of reference locations.

An apparatus includes a first section operable to detect polarization-sensitive radiation emitted by an object, and a second section operable to determine a Jones matrix based on information obtained by the first section from the polarization-sensitive radiation. The second section thereafter transforms the Jones matrix into a Mueller matrix, the Mueller matrix being representative of properties of the object.

The present invention is an alternative Fourier domain optical coherence system (FD-OCT) and its associated method. The system comprises a swept multi-wavelength laser, an optical interferometer and a multi-channel receiver. By employing a multi-wavelength laser, the sweeping range for each lasing wavelength is substantially reduced as compared to a pure swept single wavelength laser that needs to cover the same overall spectral range. The overall spectral interferogram is divided over the individual channels of the multi-channel receiver and can be re-constructed through processing of the data from each channel detector. In addition to a substantial increase in the speed of each axial scan, the cost of invented FD-OCT system can also be substantially less than that of a pure swept source OCT or a pure spectral domain OCT system.

A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral domain scanning, as an example. A fundus intensity image can be acquired in real-time. The 3-dimensional data set can be reduced to generate an anatomical mapping, such as an edema mapping and a thickness mapping. Optionally, a partial fundus intensity image can be produced from the scanning of the eye to generate an en face view of the retinal structure of the eye without first requiring a full segmentation of the 3-D data set. Advantageously, the system, method and apparatus of the present invention can provide quantitative three-dimensional information about the spatial location and extent of macular edema and other pathologies. This three-dimensional information can be used to determine the need for treatment, monitor the effectiveness of treatment and identify the return of fluid that may signal the need for re-treatment.

An eye tracker having a waveguide for propagating illumination light towards an eye and propagating image light reflected from at least one surface of an eye, a light source optically coupled to the waveguide, and a detector optically coupled to the waveguide. Disposed in the waveguide is at least one grating lamina for deflecting the illumination light towards the eye along a first waveguide path and deflecting the image light towards the detector along a second waveguide path.