Product
Patsnap Eureka
For R&D, Patsnap Eureka makes reading and utilizing patents & technical documents easy.
Patsnap Eureka AIR
Designed for self-driven R&D workflows. Generate viable solutions, solve complex R&D challenges, empower your innovation with AI.
Patsnap Eureka Materials
Designed for material experts only. Revolutionize your material R&D, from search, analyze, to developing new materials.
Feature
TechResearch
Generate reliable direction feasibility study reports for your R&D in just a few steps.
TechSeek
Discover and master advanced knowledge NOW. Basics, ideas, possibilities, all at once.
TechMind
As an expert in R&D Theories, TechMind can generates customized viable solutions instantly.
TechRisk
Analyze your overall solution with one click, know your potential R&D risks in advance.
TechMonitor
Get weekly tech updates, stay abreast of the latest tech innovations and key insights.
Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
37 results about "Retinal structure" patented technology
Efficacy Topic
Property
Owner
Technical Advancement
Application Domain
Technology Topic
Technology Field Word
Patent Country/Region
Patent Type
Patent Status
Application Year
Inventor
Structure of the retina. The retina is a light-sensitive layer of nerve tissue lining the inner surface of the eye. The retina creates an image projected on its surface with help of the cornea and crystalline lens, and transforms it into nerve impulses sent to the brain.
Enhanced optical coherence tomography for anatomical mapping
A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral domain scanning, as an example. A fundus intensity image can be acquired in real-time. The 3-dimensional data set can be reduced to generate an anatomical mapping, such as an edema mapping and a thickness mapping. Optionally, a partial fundus intensity image can be produced from the scanning of the eye to generate an en face view of the retinal structure of the eye without first requiring a full segmentation of the 3-D data set. Advantageously, the system, method and apparatus of the present invention can provide quantitative three-dimensional information about the spatial location and extent of macular edema and other pathologies. This three-dimensional information can be used to determine the need for treatment, monitor the effectiveness of treatment and identify the return of fluid that may signal the need for re-treatment.
Owner:UNIV OF MIAMI
Enhanced optical coherence tomography for anatomical mapping
ActiveUS20060119858A1Enhanced anatomical mappingReduction in total information contentEye diagnosticsUsing optical meansData setSpectral domain
A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral domain scanning, as an example. A fundus intensity image can be acquired in real-time. The 3-dimensional data set can be reduced to generate an anatomical mapping, such as an edema mapping and a thickness mapping. Optionally, a partial fundus intensity image can be produced from the scanning of the eye to generate an en face view of the retinal structure of the eye without first requiring a full segmentation of the 3-D data set. Advantageously, the system, method and apparatus of the present invention can provide quantitative three-dimensional information about the spatial location and extent of macular edema and other pathologies. This three-dimensional information can be used to determine the need for treatment, monitor the effectiveness of treatment and identify the return of fluid that may signal the need for re-treatment.
Owner:UNIV OF MIAMI
Precise disruption of tissue in retinal and preretinal structures
InactiveUS20090048586A1Reduce dispersionReduce aberrationLaser surgeryOptical measurementsWavefrontFemto second laser
Systems and methods are provided for disrupting tissue within preretinal or retinal structures of an eye. At least one femtosecond laser pulse is directed through the cornea of the eye to a target location. The at least one femtosecond laser pulse has sufficient intensity to induce nonlinear absorption in tissue within the target location. The at least one laser pulse is corrected at an adaptive optical element as to substantially reduce dispersion and aberration of the at least one laser pulse due to changes in the wavefront profile associated with the laser pulse due to travel through eye tissue between the surface of the eye and the target location. At least the target location is imaged to produce an in vivo image of the target location. The adaptive optical element is adjusted according to distortion detected in a reflected wavefront.
Owner:THE CLEVELAND CLINIC FOUND
Retina optical coherence chromatography detection-display system
ActiveCN104116495AInsufficient improvementWith see-through display functionOthalmoscopesRetinal structureMiosis
The invention relates to a retina optical coherence chromatography detection-display system. The retina optical coherence chromatography detection-display system comprises a first light path channel for displaying image information, a second light path channel for tracking retina information, a third light path channel formed by an external natural light channel and a fourth light path channel for detecting pupils. In combination with the optical waveguide display technology and the Michelson interference technology, the retina optical coherence chromatography detection-display system overcomes the defects of an original retina optical coherence chromatography detection system, can detect the structure of the retina, can be used for studying the relations between pupil movement, dilation and miosis and structural features of the retina by changing displayed images, also has fluoroscopy and display functions and can be applied to medical research, pathologic analysis, lie detection and other aspects.
Owner:BEIJING INSTITUTE OF TECHNOLOGYGY
Method and device for high-resolution retinal imaging
ActiveUS9532713B2Increase contrastImprove signal-to-noise ratioOthalmoscopesMeasurement deviceRetinal imaging
Owner:IMAGINE EYES
Dual-wavelength retinal vessel blood oxygen measuring system based on fundus camera
ActiveCN104997519AAchieve blood oxygen saturationRealize functionDiagnostic recording/measuringEye diagnosticsDiseaseOphthalmology
The invention relates to a dual-wavelength retinal vessel blood oxygen measuring system based on a fundus camera. The system comprises two parts, namely, a retinal image acquisition subsystem and a blood oxygen calculation subsystem, wherein the retinal image acquisition subsystem forms a retinal image acquired by the fundus camera to infinity through an imaging objective, and a telecentric beam path in the image space is formed. A right-angled reflecting prism splits a light beam into two ways, the light beam is reflected by reflectors and transmits interference filters with specific wavelengths to be filtered into imaging light with required wavelengths, the imaging light is imaged on a CCD (charge coupled device) target surface simultaneously after passing through the imaging objective, and dual-wavelength simultaneous retinal imaging is realized; the blood oxygen calculation subsystem finishes calculation of the retinal vessel blood oxygen saturation after performing a series of operations such as image processing, vessel extraction, light density calculation and the like on an acquired dual-wavelength retinal image. With the adoption of the system, retinal vessel function information is acquired while the retinal structure image is acquired, and a powerful tool can be provided for life science related research and diagnosis of fundus related diseases.
Owner:INST OF OPTICS & ELECTRONICS - CHINESE ACAD OF SCI +2
Methods and systems to detect and classify retinal structures in interferometric imaging data
ActiveUS10169864B1Reduce redundant processesReduce segmentation errorImage enhancementImage analysisAnatomical structuresPattern recognition
Methods and systems are presented to analyze a retinal image of an eye and assigns features to known anatomical structures such as retinal layers. One example method includes receiving interferometric image data of an eye. A set of features is identified in the image data. A first subset of identified features is associated with known retinal structures using prior knowledge. A first set of characteristic metrics is determined of the first subset of features. A second set of characteristic metrics is determined of a second subset of features. Using the characteristic metrics of the first and the second sets, the second subset of features is associated with the retinal structures. Another example method includes dividing interferometric image data into patches. The image data in each patch is segmented to identify one or more layer boundaries. The segmentation results from each patch are stitched together into a single segmentation dataset.
Owner:CARL ZEISS MEDITEC INC
Method for acquiring retina structure from optical coherence tomographic image and system thereof
ActiveUS20170132793A1Simple calculationCalculation complexity is reducedImage enhancementImage analysisComputation complexityRetinal structure
The present disclosure provides a method for acquiring a retina structure from an optical coherence tomographic image and a system thereof. The method comprises: calculating a region of interest (ROI) image of a source image; performing a Gaussian filtering of the ROI image; calculating a first estimated boundary position of a first layer boundary and a second estimated boundary position of a second layer boundary using a multi-resolution method; refining the first layer boundary and the second layer boundary respectively using a simplified active contour model according to the first estimated boundary position and the second estimated boundary position, to obtain a first initial boundary position of the first layer boundary and a second initial boundary position of the second layer boundary; smoothing the first initial boundary position and the second initial boundary position using a filtering method; acquiring segmentation positions of rest layer boundaries in the ROI image according to a segmented position of the first layer boundary and a segmented position of the second layer boundary. The present disclosure can improve the calculation speed and reduce the calculation complexity while maintaining high location accuracy.
Owner:SHENZHEN INST OF ADVANCED TECH
Method and device for high-resolution retinal imaging
ActiveUS20130308098A1Improve signal-to-noise ratioIncrease contrastOthalmoscopesMeasurement deviceRetinal imaging
The invention relates to a high-resolution retinal imaging method and device notably comprising an emission source (LSr) for emitting a light beam for the illumination of the retina of an eye (10) of a subject, a detection device (12) capable of detecting spatial-frequency structures of 250 cycles / mm measured in the plane of the retina, an optical imaging system (16) allowing for the formation of an image of at least a part of the retina on the detection device (12), a device (15) for measuring optical defects with an analysis plane of the optical defects, a correction device (14) comprising a correction plane and intended to correct, in said correction plane, the light rays from said emission source (LSr) and backscattered by the retina as a function of the optical defects measured by the measurement device (15). The correction and analysis planes are optically conjugated with a predetermined plane (17) of the eye, and the input pupil of said optical imaging system has a diameter of between a first value Φmin and a second value Φmax, the first value being defined to allow for the detection by said detection device (12), at an imaging wavelength, of structures of the retina exhibiting a spatial frequency of 250 cycles per millimeter, and the second value being less than 5.75 mm.
Owner:IMAGINE EYES
Cataract OCT image restoration method and system based on machine learning
ActiveCN112700390AReduce the numberSolve unpaired problemsImage enhancementImage analysisInformation processingFrequency spectrum
The invention discloses a cataract OCT image restoration method and system based on machine learning. The cataract OCT image restoration method introduces an optical information processing technology, changes the frequency spectrum of an object through an optical spatial filter, carries out the amplitude, phase or composite filtering of an inputted image, and carries out the fuzzy processing of the image, thus achieving the simulation of a cataract OCT fuzzy image; then the neutral density attenuation sheet is added to an OCT scanner lens to scan healthy eyeballs, a fundus OCT blurred image is obtained to simulate a cataract image, then an OCT clear image of the same person without the attenuation sheet is scanned, and the cataract retina OCT blurred image is restored into a clear image. The ten layers of retina structures can be clearly seen from the restored image, and the number of network models is reduced, so that the workload and the total training time are reduced, and the technology of restoring the blurred image to be clear is realized only by using the Pix2pix model.
Owner:SHANTOU UNIV
Method of imaging multiple retinal structures
ActiveUS20160317031A1Uniform retinal irradianceMinimize exposureImage enhancementImage analysisRetinal structureMethod of images
Methods and apparatus for imaging multiple retinal structures and montaging of multiple retinal images are provided. The method involves cross-correlating images from different imaging channels to compensate for intra-frame distortion due to retinal movement during image acquisition, and conducting a second cross-correlation to filter out any motion artifacts in the images. The resultant images are combined to generate a composite image. The method also involves controlling light directed on the retina spatially and temporally.
Owner:UNIVERSITY OF ROCHESTER
Compound soft capsule for relieving asthenopia, improving eyesight, resisting oxidation and protecting retina and preparation method
InactiveCN108968069ASuppress generationInhibit lipid peroxidationLipidic food ingredientsFood shapingRetinal structureOxygen
The invention is suitable for technical field of health-care food and provides a compound soft capsule for relieving asthenopia, improving eyesight, resisting oxidation and protecting retina and a preparation method. The compound soft capsule comprises a content and a capsule skin; the content comprises the following materials in parts by weight: 38-50 parts of xanthophyll extract, 155-180 parts of procyanidine extract, 255-270 parts of soybean oil and 14-23 parts of beewax; the capsule skin comprises the following materials in parts by weight: 230-260 parts of gelatin, 118-130 parts of glycerinum, 235-260 parts of deionized water and 1-2 parts of titanium oxide. In the compound soft capsule, the xanthophyll extract and the procyanidine extract extracted from natural plants are combined with materials, such as soybean oil and beewax. The xanthophyll extract and the procyanidine extract have a synergistic effect, have excellent oxidation resistance, are capable of effectively removing free radicals and restraining the generation and lipid peroxidation of crystalline oxygen radicals, and meanwhile supplementing the xanthophyll required by human body, have an excellent protecting function for retina structure, can effectively relieve eye uncomfortable symptoms, such as asthenopia, and have high safety.
Owner:BEIJING YUANLAI HEALTH MANAGEMENT CO LTD
Biologic sclera contraction band and preparing method thereof
The invention discloses a biologic sclera contraction band and a preparing method thereof. The biologic sclera contraction band is in a band as a whole; the cross section of the biologic sclera contraction band is arc-shaped; the biologic sclera contraction band is thickest in the middle and gradually becomes narrower from the middle to the two sides through arc-shaped transition; the whole length of the biologic sclera contraction band is 3-40mm; the middle thickness of the biologic sclera contraction band is 1-3mm; the thickness of the two sides of the biologic sclera contraction band is 0.5-2mm; the band width of the biologic sclera contraction band is 3-8mm. The biologic sclera contraction band can be applied to combination with a biologic posterior sclera reinforcing band, can contract sclera and limit the expansion of the sclera, is used for treating high myopia macular retinal detachment, full retinal detachment and other certain non-incremental retinal detachments and better keeps and protects retinal structures and functions. The base material of the biologic sclera contraction band is taken from the trachea, ligament, trunk vessel or cartilage of an animal, the strength is increased through genipin cross-linking solidifying treatment, the elasticity and the hardness are proper, and the biologic sclera contraction band cannot be easily absorbed, has great tissue compatibility, causes few complications and overcomes the defects of the conventional retinal detachment intra and extra surgeries.
Owner:薛安全
Systems and methods for combined structure and function evaluation of retina
According to one or more embodiments, systems and methods that combine structural examination capabilities of one device with functional examination capabilities of another device to perform a separate or combined structural and functional evaluation of visual functions of the patient's eyes are described herein. A system for combined structural and functional evaluation of a retina may include a structural evaluation unit which may be an OCT, PS-OCT, SLO or PS-SLO and a functional evaluation unit which may be a perimeter, microperimeter, or any other type of visual field analyzer. The structural evaluation unit and the functional evaluation unit may be located within a same housing, and thus may be utilized as a single device. The structural evaluation unit may record structural measurements associated with the patient's eye or retina and the functional evaluation unit may record functional measurements associated with the patient's field of view.
Owner:NIDEK CO LTD
Methods and systems to detect and classify retinal structures in interferometric imaging data
ActiveUS20190108636A1Improve segmentationReduce calculationImage enhancementImage analysisAnatomical structuresData set
Methods and systems are presented to analyze a retinal image of an eye and assigns features to known anatomical structures such as retinal layers. One example method includes receiving interferometric image data of an eye. A set of features is identified in the image data. A first subset of identified features is associated with known retinal structures using prior knowledge. A first set of characteristic metrics is determined of the first subset of features. A second set of characteristic metrics is determined of a second subset of features. Using the characteristic metrics of the first and the second sets, the second subset of features is associated with the retinal structures. Another example method includes dividing interferometric image data into patches. The image data in each patch is segmented to identify one or more layer boundaries. The segmentation results from each patch are stitched together into a single segmentation dataset.
Owner:CARL ZEISS MEDITEC INC
Method for performing fundus refractive compensation judgment and imaging optimization by using OCT signal
ActiveCN112168132ATo overcome the problem that the position will have a large inclinationLow costImage enhancementImage analysisOphthalmologyRetinal imaging
The embodiment of the invention discloses a method for performing fundus refractive compensation judgment and imaging optimization by using an OCT signal. The method comprises the following steps of:S1, controlling a reference arm optical path: finding a retina structure in an image and adjusting the retina structure to a proper position in the image by calculating the concavity and convexity ofthe retina structure and an imaging position; S2, performing automatic refractive compensation: controlling the optical path difference between the reference arm optical path and a sample arm scanningbeam optical path to be a fixed value, and finding an image with the strongest signal through a hill climbing method for refractive compensation; S3, performing left-right fine adjustment on the retina structure: judging the left-right deviation of the retina structure, and controlling a Y-axis motor to perform horizontal adjustment according to the deviation; and S4, adjusting the retina imagingposition: adjusting the reference arm optical path again according to the image intensity so as to adjust the height position of the retina in the image. According to the method for performing fundusrefractive compensation judgment and imaging optimization by using the OCT signal, the cost can be reduced, rapid and accurate refractive compensation can be realized, and meanwhile, retina imaging is optimized.
Owner:SUZHOU UNIV
Systems and method for detecting cognitive impairment
PendingUS20220079506A1Low costReduce complexityImage enhancementImage analysisOphthalmologyElectroretinography
Systems, methods, and computer readable media for determining cognitive impairment (CI) in patients are provided herein. Various regional structural-functional parameters of the retina can serve as biomarkers for the detection of CI. The method can include forming a database including a quantification of retinal structure and retinal function of a plurality of eyes associated with a plurality of patients, providing a baseline cognitive impairment (CI) reference. The method can include determining a measure of functionality of neurons in the retina based on an electroretinogram (ERG) of a patient. The method can include determining a structural measure of the first retina based on a generalized dimension spectrum and singularity spectrum of the skeletonized retinal image, and a lacunarity parameter of the skeletonized retinal image. The method can include determining a level of cognitive impairment based on the structural and functional measures.
Owner:UNIV OF MIAMI
Device for reliably determining biometric measurement variables of the whole eye
A device for determining biometric variables of the eye, as are incorporated in the calculation of intraocular lenses including a multi-point keratometer and an OCT arrangement. The keratometer measurement points are illuminated telecentrically and detected telecentrically and the OCT arrangement is designed as a laterally scanning swept-source system with a detection region detecting the whole eye over the whole axial length thereof. The multi-point keratometer ensures that a sufficient number of keratometer points are available for measuring the corneal surface. By contrast, telecentricity ensures that the positioning inadequacies of the measuring instrument in relation to the eye to be measured do not lead to a local mismatch of the reflection points. The swept-source OCT scan detects the whole eye over the length thereof so that both anterior chamber structures and retina structures can be detected and a consistent whole eye image can be realized.
Owner:CARL ZEISS MEDITEC AG
Device for reliably determining biometric measurement variables of the whole eye
A device for determining biometric variables of the eye, as are incorporated in the calculation of intraocular lenses including a multi-point keratometer and an OCT arrangement. The keratometer measurement points are illuminated telecentrically and detected telecentrically and the OCT arrangement is designed as a laterally scanning swept-source system with a detection region detecting the whole eye over the whole axial length thereof. The multi-point keratometer ensures that a sufficient number of keratometer points are available for measuring the corneal surface. By contrast, telecentricity ensures that the positioning inadequacies of the measuring instrument in relation to the eye to be measured do not lead to a local mismatch of the reflection points. The swept-source OCT scan detects the whole eye over the length thereof so that both anterior chamber structures and retina structures can be detected and a consistent whole eye image can be realized.
Owner:CARL ZEISS MEDITEC AG
Macular area positioning system based on retina structure
PendingCN112581439AReduce time lossEnables automatic macular area localizationImage enhancementImage analysisOphthalmologyRetinal structure
The invention provides a macular area positioning system based on a retina structure, and relates to the technical field of macular positioning. Based on retinal blood vessels and an optic disc in a fundus image, parameters of the optic disc and parameters of the blood vessels are calculated; and a main vascular arch structure of a retina result is determined based on the parameters of the blood vessel and the optic disc, and a macular area position is obtained according to the structure. According to the system, automatic macular area positioning based on the retina structure is achieved, thetime loss of each image needing to be manually labeled is saved, automatic macular area positioning based on the retina structure is achieved, the time loss of each image needing to be manually labeled is saved, and tests show that the system is accurate, reliable, robust and high in practicability and meets the retina macular region positioning requirements of human doctors.
Owner:中科泰明(南京)科技有限公司
Application of tripterine to preparation of medicine treating degenerative retinopathy related diseases
InactiveCN105343107AInjury treatment and improvementEasily damagedOrganic active ingredientsSenses disorderDiseaseDiabetes retinopathy
The invention relates to application of tripterine to preparation of medicine treating degenerative retinopathy related diseases. A mouse model suffering from retinal photodamage is adopted to simulate a common pathological link in various degenerative retinopathy generation processes, that is, death of photoreceptor cells; the photoreceptor cell death preventing function and the degenerative retinopathy preventing function of tripterine are researched, wherein the results show that tripterine can be used for inhibiting mass dead of the photoreceptor cells and structural damage and functional injury of a retina caused by photodamage, and is very obvious in degenerative retinopathy treating effect. Therefore, tripterine can be used for preparing medicine treating various types of degenerative retinopathy including age related macular degeneration, retinitis pigmentosa, Stargardt disease, cone-rod dystrophy, diabetic retinopathy and the like, or preparation of reagents used in related scientific researches.
Owner:YUEYANG INTEGRATED TRADITIONAL CHINESE & WESTERN MEDICINE HOSPITAL SHANGHAI UNIV OF CHINESE TRADITIONAL MEDICINE +1
Label-free contrast enhancement for translucent cell imaging by purposefully displacing the detector
A method for imaging vertebrate translucent retinal structures includes imaging a translucent retinal structure at a first imaging plane in the retina with a light source focused at such first imaging plane, and detecting reflected light with a non-confocal off-axis detector, wherein the detector is axially displaced from a plane conjugate to the first imaging plane to a plane conjugate to a reflective layer deeper in the retina along a path of illumination from the light source. The method may employ scanning ophthalmic instruments, and enables an enhancement in contrast and collected intensity by axially displacing the image detector away from the object of interest to positions closer to conjugate to layers of strong retinal reflection, like the photoreceptors or the interface between the choroid and the sclera, that act as a diffusive screen. This improvement was found using a model that describes the source of the contrast in offset aperture and split-detector ophthalmoscopy by emphasizing the role of cellular refractive index change within the plane of illumination.
Owner:UNIVERSITY OF ROCHESTER
Method of imaging multiple retinal structures
ActiveUS10092181B2Minimize exposureUniform retinal irradianceImage enhancementImage analysisRetinal structureMethod of images
Methods and apparatus for imaging multiple retinal structures and montaging of multiple retinal images are provided. The method involves cross-correlating images from different imaging channels to compensate for intra-frame distortion due to retinal movement during image acquisition, and conducting a second cross-correlation to filter out any motion artifacts in the images. The resultant images are combined to generate a composite image. The method also involves controlling light directed on the retina spatially and temporally.
Owner:UNIVERSITY OF ROCHESTER
Method and apparatus for determining a scattering spectrum of an eye
Embodiments of the present invention provide a computer-implemented method of determining a scattering spectrum of an eye. The method comprises receiving data from a detector indicative of a reflected wave of radiation reflected from the retina, wherein the reflected wave of radiation is formed by an incident wave of masked radiation directed towards a retina of the eye, such that at least one region masked from the incident wave is present on the retina, determining a first back scattering spectrum indicative of light scattered from an optical media of the eye in dependence on a portion of the reflected wave of radiation corresponding to the at least one masked region, determining a second back scattering spectrum indicative of light scattered from a neural retina of the eye in dependence on retinal structure information representative of neural retinal structure, and determining the scattering spectrum of the eye in dependence on the first back scattering spectrum and the second back scattering spectrum.
Owner:UK RES & INNOVATION LTD
Device and method for non-invasive recording of the ERG and VEP response of an eye
ActiveUS10398340B2More reliableFaster and less invasiveElectroencephalographyEye surgeryVisual cortexDiabetes retinopathy
The present invention refers to the field of ophthalmology, and in particular to that of devices and methods for supporting the diagnosis of important eye pathologies such as Age-related Macular Degeneration (AMD), Diabetic Retinopathy (DR), anomalies and dysfunctions of the retina and of sight in general such as degeneration of the retinal structure of the optical nerve and of the visual cortex. More specifically, the invention concerns a new device and method for recording the electroretinogram (so-called ERG) of an eye, i.e. the bioelectric response of the retina induced by a light stimulus, through the eyelid.
Owner:C S O SRL
Compensating for polarization changes introduced by components with retardation in polarization-sensitive retinal scanning systems
An optical apparatus uses polarized light to interrogate birefringence properties of the retina to detect the fixation condition of the eye by sensing characteristic birefringence patterns of the retinal structures. Optical components, as well as optional additional components, interfere with the polarization measurements by introducing unwanted retardance which alters the polarization state of the light entering the eye and of the light reaching the detection system. Compensating retarders are provided to nullify the effect of unwanted retardance in the forward and return light paths so the polarization states of the light entering the eye and the light reaching the detection system are not contaminated by the effects of the unwanted retardance. Mueller matrices are used to mathematically calculate the parameters for the compensating retarders for the unwanted retardance. A variable retarder system may also be provided to compensate for the corneal birefringence of the eye via feedback control.
Owner:THE JOHN HOPKINS UNIV SCHOOL OF MEDICINE
Eye Phantom for Evaluating Retinal Angiography Image
PendingUS20220000356A1Accurately evaluating performanceGuarantee smooth developmentEducational modelsOthalmoscopesOphthalmologyRetinal structure
The present invention relates to an eye phantom for evaluating a retinal angiography image, and a manufacturing method therefor. A purpose of the present invention is to provide an eye phantom for evaluating a retinal angiography image, capable of simulating even the vascular structure and blood flow of a retina so as to be more similar to an actual retinal structure than a conventional eye phantom; and a manufacturing method therefor. More specifically, a purpose of the present invention is to provide an eye phantom for evaluating a retinal angiography image, including various shapes of fine fluid channel structures corresponding to the vascular structure formed in an actual retina; and a manufacturing method therefor.
Owner:KOREA RES INST OF STANDARDS & SCI
Device and method for non-invasive recording of the erg and vep response of an eye
ActiveUS20180110437A1Eliminating invasivenessReduce the risk of contaminationElectroencephalographyEye surgeryDiabetic retinopathyVisual cortex
The present invention refers to the field of ophthalmology, and in particular to that of devices and methods for supporting the diagnosis of important eye pathologies such as Age-related Macular Degeneration (AMD), Diabetic Retinopathy (DR), anomalies and dysfunctions of the retina and of sight in general such as degeneration of the retinal structure of the optical nerve and of the visual cortex. More specifically, the invention concerns a new device and method for recording the electroretinogram (so-called ERG) of an eye, i.e. the bioelectric response of the retina induced by a light stimulus, through the eyelid.
Owner:C S O SRL
A Simple, Efficient and Mechanizable Induction Method for Differentiation of Human Pluripotent Stem Cells into Retinal Tissue
ActiveCN109423480BGather as soon as possibleRealize mechanized operationNervous system cellsArtificially induced pluripotent cellsMedicineRetinal structure
The invention discloses a simple, efficient and mechanizable induction method for human pluripotent stem cells to differentiate into retinal tissues. It includes digesting hPSCs to obtain cell pellets, and then culturing the cell pellets to obtain embryoid bodies, which are induced to differentiate to obtain 3D retinal tissues, characterized in that the hPSCs are digested to obtain cell pellets, and then the cell pellets are cultured to obtain pseudo The embryoid body is digested into single cells from hPSCs, and then the cells are collected and added to the culture vessel, and the cells reunite to form an embryoid body. The invention can make the induction, differentiation and acquisition of retinal tissue an assembly line operation, and can realize factory production for large-scale clinical application or drug screening.
Owner:ZHONGSHAN OPHTHALMIC CENT SUN YAT SEN UNIV
Who we serve
- R&D Engineer
- R&D Manager
- IP Professional
Why Patsnap Eureka
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com