1248 results about "Neurosurgery" patented technology

This invention relates to the working end of a medical instrument that applies energy to tissue. In one embodiment, the instrument has a microfluidic tissue-engaging surface fabricated by soft lithography means together with optional superlattice cooling means that allows for very precise control of energy application, for example in neurosurgery applications. The tissue-engaging surface can eject a high-heat content vapor into the engaged tissue for treating tissue, while the superlattice cooling structure can prevent collateral thermal damage. Also, the superlattice cooling structure can be used to localize heat at a selected depth in tissue and prevent surface ablation. Also, the superlattice cooling structure can be used to prevent tissue sticking to a thermal energy delivery surface. In another embodiment, the tissue-engaging surface can be used in a jaw structure for sealing tissue together with hydrojet means for transecting the tissue.

Minimally invasive neurosurgical intracranial robot system is introduced to the operative site by a neurosurgeon through a narrow surgical corridor. The robot is passed through a cannula and is attached to the cannula by a latching mechanism. The robot has several links interconnected via revolute joints which are tendon-driven by tendons routed through channels formed in the walls of the links. The robot is teleoperatively guided by the neurosurgeon based on real-time images of the intracranial operative site and tracking information of the robot position. The robot body is equipped with a tracking system, tissue liquefacting end-effector, at as well as irrigation and suction tubes. Actuators for the tendon-driven mechanism are positioned at a distance from the imaging system to minimize distortion to the images. The tendon-actuated navigation of the robot permits an independent control of the revolute joints in the robot body.

An embodiment of the invention provides a navigation and location system and method adopting a neurosurgical robot. The navigation and location system comprises motion execution equipment, a spatial position sensor, a matched position marking unit and a host, wherein the host is connected with the motion execution equipment and the spatial position sensor and used for creating surgical planning on a digital graphic image, and the surgical planning contains a position positioned to a lesion part independently and precisely as well as a motion path; the spatial position sensor is used for capturing the matched position marking unit, so that the position mapping of different space coordinates systems can be finished by the host; the motion execution equipment carries surgical instruments, is used for performing independent and precise positioning on the lesion part according to a specific motion scheme generated on the basis of the position positioned to the lesion part, the motion path and the position mapping of the different space coordinates systems, and is further used for stabilizing and locking the surgical instruments and then supporting surgery.

The present invention was developed by a neurosurgeon and seeks to mimic the results of primate neurological research which is indicative of a human's actual neurological control structures and logic. Specifically, the motor proprioceptive and tactile neurophysiology functioning of the surgeon's hands and internal hand control system from the muscular level through the intrafusal fiber system of the neural network is considered in creating the robot and method of operation of the present invention. Therefore, the surgery is not slowed down as in the art, because the surgeon is in conscious and subconscious natural agreement and harmonization with the robotically actuated surgical instruments based on neurological mimicking of the surgeon's behavior with the functioning of the robot. Therefore, the robot can enhance the surgeon's humanly limited senses while not introducing disruptive variables to the surgeon's naturally occurring operation of his neurophysiology. This is therefore also a new field, neurophysiological symbiotic robotics.

The invention is a manufacturing method for titanium alloy cranial bone dummy, applies to cranial nerves surgery cranial bone renovation field. The invention assembles the dummy based on the CT picture of patient; the character lies in: the computer with universal image processing software and back designing software reconstructs the three-dimension prototype of patient head after dividing the fracture image, designs the dummy of defect part according to the three-dimension prototype, and the designed dummy curved surface is guided into multi-point forming system and quick-prototype system to press titanium network board and produce dummy slice model, finally forms the terminal dummy through comparing and cutting the titanium network board; the invention uses multi-point forming technology to compress the dummy quickly, it can uses the softness character of mouldless multi-point to compress the dummy in order to solves the back springing problem. The cost is low, the speed is high.

A thermally modified microbial-derived cellulose material is described for use as an implantable material in general surgery, plastic surgery and neurosurgery.

The system comprises at least three anchors (2,2′,2″) intended to be attached to the patient and equipped with markers (5,5′,5″), an insertion guide device (6) with an insertion guide (7) intended to be attached to said anchors (2,2′,2″), an external calibration device (8) with at least three calibration markers (10,10′,10″) corresponding to said markers (5,5′,5″) and a planning and imaging software. The planning and imaging software is used to determine the position of a target point in the patient with respect to the markers (5,5′,5″), the calibration device is used to calibrate and orient the insertion guide (7) of the insertion guide device (6) mounted on said calibration markers (10,10′,10″) using the determination of the software before the insertion guide device is mounted on said markers (5,5′,5″) attached to the patient.

The present invention was developed by a neurosurgeon and seeks to mimic the results of primate neurological research which is indicative of a human's actual neurological control structures and logic. Specifically, the motor proprioceptive and tactile neurophysiology functioning of the surgeon's hands and internal hand control system from the muscular level through the intrafusal fiber system of the neural network is considered in creating the robot and method of operation of the present invention. Therefore, the surgery is not slowed down as in the art, because the surgeon is in conscious and subsconscious natural agreement and harmonization with the robotically actuated surgical instruments based on neurological mimicing of the surgeon's behavior with the functioning of the robot. Therefore, the robot can enhance the surgeon's humanly limited senses while not introducing disruptive variables to the surgeon's naturally occurring operation of his neurophysiology. This is therefore also a new field, neurophysiological symbiotic robotics.

A catheter assembly for insertion into the brain. The assembly comprises a first length of tubing made of a first material. A second material surrounds the first length of tubing, the second material being more flexible than the first material and having a hardness of less than 50 Rockwell E. The second material provides damping to the first length of tubing.

A neurosurgical instrument includes a radiation detecting sensor adjustably positioned proximate a distal end of an arm of the instrument. A controller is programmed to receive and process electrical signals from the sensor. The controller operates to control an audio tone generator to emit a tone of higher intensity as the surgeon moves the sensor and its associated coagulator closer to radioactively tagged malignant tissue or a brain tumor of a patient, and of lower intensity as the coagulator moves away from the tissue or tumor, thereby permitting the surgeon to accurately locate and remove the malignant tissue or brain tumor. Also, in place of or in combination with the audio tone generator, a light emitter provides for emitting light of intensity directly related to the distance the sensor is from the malignant tissue or brain tumor tagged with a radioactive isotope.

The invention discloses a main operation hand for a minimally invasive neurosurgery robot on the basis of wire rope gearing. The main operation hand comprises a base, a first joint transmission mechanism, a second joint transmission mechanism, a third joint transmission mechanism, a wrist transmission mechanism and an opening and closing mechanism. By means of the layout mode that a motor is arranged in front of the base, the weight of all parts of the mechanisms of the main operation hand can be greatly lowered, then the rotating inertia of the main operation hand is reduced, and the rigidity of the mechanisms can be easily improved; wire rope gearing is adopted for first three joints of the mechanisms, and therefore the sizes of all the parts in the mechanisms are effectively reduced, and the mechanisms are more compact; by means of wire rope gearing, through appropriate tensioning, the return difference problem can be effectively solved; through the serial connection of the mechanisms and the reasonable joint layout, the working space of the mechanisms is enlarged, and the main operation hand better conforms to operation habits of a doctor.

The invention relates to a head and facial marker semiautomatic calibration method for a neurosurgical stereotactic surgery. The method includes aiming to a feature that automatic calculation of a computer requires quantization rules, after selecting an initial marking point, selecting relative points as facial points on the head of a patient according to a certain rule; and allowing a computer software system to calculate corresponding facial marking points automatically according to a relative rule, and thus, applying the two groups of the marking points to realize registration between space and image space of the patient. The method can be used under the condition of unadaptable or insufficient time to stick facial markers, head and facial features of the patient can be selected by a computer in three-dimensional images semiautomatically, and the neurosurgical stereotactic surgery without sticking marking points outside and a frame can be performed.

The invention discloses an adjustable viewing angle endoscope for a minimally invasive neurosurgery robot. The adjustable viewing angle endoscope for the minimally invasive neurosurgery robot comprises a lens module, a controllable snakelike module, an endoscope rod and a drive system mounted in a drive box, the drive box is fixedly connected with one end of the endoscope rod; the endoscope can adjust the viewing angle for wide range; the viewing angle can be adjusted along any direction, the use is convenient, the operation fault is reduced and the operation efficiency is raised.

The present invention incorporates new materials for bone regeneration, methods for their manufacture, and application in traumatology surgery, maxillo facial surgery, dental surgery, orthognatic surgery, endodontics, ophthalmology, neurosurgery and / or osteoporotic processes, and other indications where bone regeneration is required. In particular, the present invention incorporates synthetic materials with a 20% to a 95%, preferably between 40% and 90% in mass of monetite [Ca1-XMXHPO4, where 0≦x≦0.05, and where M can be a divalent metallic ion], and which in their final composition incorporate between 5% and 80%, preferably between 0% and 60%, in mass of bioactive calcium compounds chosen from calcium phosphates and between 5% and 80% in total mass of bioactive silicon compounds chosen from calcium silicates and / or bioactive silica glasses and gels.

The invention discloses a preparation process of dalteparin sodium. The preparation process comprises the following steps: preparing a heparin sodium solution, a heparin degradation fluid, a reducing solution and a crude product, refining, freeze-drying and the like. The average molecular weight of the obtained product is 5,500 to 6,500, the peak molecular weight is 3,500 to 6,000, a component with the molecular weight of less than 3,000 is not greater than 13% , a component with the molecular weight of greater than 8,000 is not greater than 15%, anti-Xa activity is more than or equal to 130IU / mg. The invention has the advantages of rich source of raw materials, high yield, stable and reliable quality, high purity, low cost, simple process, easiness in operation and no waste discharge. The dalteparin sodium has the anticoagulant, antithrombotic, anti-tumor, anti-inflammatory, anti-allergy and blood lipid regulating effects, thereby having a significant curative effect. The dalteparin sodium can be used for preventing preoperative and postoperative thrombosis of general surgery, orthopedic surgery and neurosurgery, effectively preventing venous thromboembolism of ischemic stroke patients, greatly reducing the risk of stroke, effectively preventing the solidification caused by extracorporeal circulation of blood, effectively preventing the instable coronary heart disease, and having a wide usable range.

The system comprises at least a support (5) to be attached to a patient by fixing means (4), said support having an outer thread (7), a first nut (9) with an inner thread (11) cooperating with said outer thread (7); and an anchor having a spherical bottom end (10) being placed between said support and said nut, a spherical head (15) said spherical bottom end and head being linked by a shaft, a second nut (16) having an inner thread (17) and intended to be screwed on an external device having a corresponding thread (31), such as a platform (20) or a surgical device (30), whereby the tightening of at least one of the nuts (9,16) on the support and / or on the external device allows to block the position of the anchor.

A hydrogel tissue adhesive having increased degradation time is described. The hydrogel tissue adhesive is formed by reacting an oxidized polysaccharide with a water-dispersible, multi-arm amine in the presence of a polyol additive, which retards the degradation of the hydrogel. The hydrogel may be useful as a tissue adhesive or sealant for medical applications, including but not limited to, ophthalmic applications such as sealing wounds resulting from trauma such as corneal lacerations, or from surgical procedures such as vitrectomy procedures, cataract surgery, LASIK surgery, glaucoma surgery, and corneal transplants; neurosurgery applications, such as sealing the dura; as a plug to seal a fistula or the punctum; adhesion prevention to prevent undesired tissue to tissue adhesions resulting from trauma or surgery; and as a hemostat sealant.

The invention discloses a method for preparing enoxaparin sodium, comprising the steps of salinizing, drying, esterfying, alcohol precipitating, oxidizing, alcohol precipitating, fine filtering and freeze drying. In the method provided by the invention, a hydrophilic liquid phase reaction, a hydrophobic liquid phase reaction and a solid phase reaction are adopted, so that macromolecule sodium heparin is degraded into micromolecule sodium heparin with a specific structure, and the molecular weights of products and molecular weight distribution ranges are controlled, thus anti-FIIa activity resulting in bleeding risk is greatly reduced, the anti-FXa activity is relatively improved, and the product effectiveness and safety advantages are obvious. The enoxaparin sodium can be used for effectively preventing venous thromboembolism and pulmonary embolism, can be used for thrombosis before and after operations of orthopedic surgery and neurosurgery, and can be used for greatly reducing apoplexy risk, more effectively reducing death, cardiac failure and recurrent angina of patients suffering from unstable coronary artery syndromes, reducing hypertriglyceridemia and effectively eliminating the side effects of haemorrhage, osteoporosis and induced thrombocytopenia after long-term use of common unfractionated heparin sodium and derivates of common unfractionated heparin sodium.

A tissue cutting device that is especially suited for neurosurgical applications is disclosed and described. The device includes a handpiece and an outer cannula in which a reciprocating inner cannula is disposed. The device is configured to provide multiple functions during a surgical procedure, in addition to resecting tissue, with a single insertion of the device into a patient.

The invention discloses a neurosurgery clinical nursing head fixing device. The device comprises a chassis, a gearbox is arranged in the chassis, an adjusting threaded rod is arranged on the upper endof the gearbox, a threaded sleeve is arranged on the upper end of the adjusting threaded rod, the upper end of the threaded sleeve is connected with a hinged frame, the hinged frame is connected to the lower end surface of a pillow seat, limit sliding grooves are formed in the left and right sides of the inside of the pillow seat, the limit sliding grooves are provided with a rotating threaded rod and a threaded sliding block, the upper end of the threaded sliding block is provided with a connecting block, the upper end of the connecting block is provided with a fixing plate, the fixing plateis a curved plate, and the inner side surface of the fixing plate is provided with a sponge pad. The device is stable in structure, stable in operation, convenient to adjust, convenient to use and quick in loading and unloading, is capable of achieving a head fixing function for clinical nursing of neurosurgery, can be applied to the head fixing of different patients, has wide applicability, canachieve the lifting adjustment function, can achieve the rotation function, provides convenience for the operation of a surgery and the nursing function, and satisfies the current use requirements.

A robotic device for performing intracranial procedures, comprising a baseplate for mounting on the subject's skull and a rotatable base element rotating on the baseplate. The rotatable base element has a central opening through which a cannulated needle can protrude such that it can rotate around an axis perpendicular to the baseplate. This cannulated needle is robotically controlled to provide motion into and out of the subject's skull. A flexible needle is disposed coaxially within the cannulated needle, and it is controlled to move into and out of a non-axial aperture in the distal part of the cannulated needle. Coordinated control of the insertion motion of the cannulated and flexible needles, and rotation of the combined cannulated / flexible needle assembly enables access to be obtained to a volume of a region of the brain having lateral dimensions substantially larger than the width of the cannulated needle.

An embodiment in accordance with the present invention provides a technique for localizing structures of interest in projection images (e.g., x-ray projection radiographs or fluoroscopy) based on structures defined in a preoperative 3D image (e.g., MR or CT). Applications include, but are not limited to, spinal interventions. The present invention achieves 3D-2D image registration (and particularly allowing use with a preoperative MR image) by segmenting the structures of interest in the preoperative 3D image and generating a simulated projection of the segmented structures to be aligned with the 2D projection image. Other applications include various clinical scenarios involving 3D-2D image registration, such as image-guided cranial neurosurgery, orthopedic surgery, biopsy, and radiation therapy.

The invention relates to dura substitutes to be used as prostheses for dural defects in the field of neurosurgery and processes for producing the same. The present invention provides artificial dura mater materials comprising sheets of microbial-derived polysaccharide processed to have the necessary strength characteristics, conformability and physical properties.

The invention discloses a multi-purpose clinical treatment device for the neurosurgery department. The multi-purpose clinical treatment device comprises a bed board, wherein the front end of the bed board is in sliding connection with an opening end of a U-shaped slider, two positioning suckers are adsorbed to the upper surface of the bed board, a fastening bolt is arranged on the front side face of the slider corresponding to the bed board, a single chip microcomputer is fixed to the right end of the front side face of the slider, a first stepping motor is fixed on the upper surface of the slider, an output shaft of the first stepping motor is fixedly connected with the lower end of a second electric telescopic rod through a coupler, when a patient moves unconsciously, the position of a wound moves, the single-chip microcomputer controls a first electric telescopic rod, the second electric telescopic rod, the first stepping motor, a third electric telescopic rod and a second stepping motor to work, so that a baking lamp always irradiates a wound, and the treatment effect is good; the single-chip microcomputer detects the distance between the positioning suckers and the baking lamp through a visual sensor, then the detection for the position of the wound is converted into the detection for the positions of the positioning suckers, and the positioning is simple and accurate.

A catheter assembly for insertion into the brain. The assembly comprises a first length of tubing made of a first material. A second material surrounds the first length of tubing, the second material being more flexible than the first material and having a hardness of less than 50 Rockwell E. The second material provides damping to the first length of tubing.

The invention discloses a dual-pinhole fixing device for the neurosurgery department, and belongs to the technical field of medical instruments. According to the technical scheme, the dual-pinhole fixing device for the neurosurgery department includes a fixing rack and a machine body, a fixing clip base is arranged at the lower side of the fixing rack, a tightening handle is arranged on the uppersurface of the fixing clip base and assembled with the fixing clip base through handle tightening nuts, and a bed body tightening baffle is arranged at the lower side of the tightening handle and assembled with the tightening handle through a baffle synchronous rotating connector. The dual-pinhole fixing device for the neurosurgery department has the advantages of being simple in structure, convenient to use and capable of conducting fast and effective fixation on double-layer or multi-layer tissue, and therefore the surgery difficulty is greatly decreased.

The invention relates to a high-efficiency bio gel sealant and application thereof, which consists of main gel lyophilized powder, catalyst lyophilized powder, main gel cytolysate and catalyst cytolysate; during use, the main gel lyophilized powder is dissolved in the main gel cytolysate and the catalyst lyophilized powder is dissolved in the catalyst cytolysate, which are respectively absorbed in an aseptic injector of a double-cavity liquid pusher; the two solution are evenly mixed by the conehead of the double-cavity liquid pusher, and then sprayed on the wounds after surgery and bleeding, so as to form a semi-transparent ivory film; the invention also discloses a method of preparing all components of the high-efficiency bio gel sealant, including preparation of the main gel lyophilized powder, the catalyst lyophilized powder, etc. with pig blood as the raw material; the product of the invention is an absorbable bio gel combination which can be used immediately for blood stopping, sealing and adhesion of tissues, and is widely applicable in surgery fields, such as general surgery, orthopedics, cardiothoracic surgery, neurosurgery, obstetrics and gynaecology, etc.