The invention relates to a medical graft, which is applied to various artificial prosthesis cardiac valves. A fine structure form on the surface of an artificial cardiac valve is designed through determining the structural geometric parameters that are a, b, and h according to a biological prototype of the cardiac valve, the apparent contact angle calculation formula of the surface which is denoted by the geometric parameters is deduced, the proper fine structural geometric parameters are determined according to the calculation formula to lead the apparent contact angle on the cardiac valve surface to be larger than 150 degrees, so as to gain a more ideal super-hydrophobic surface; then a template which is provided with a fine structure surface is processed by utilizing the technology of femtosecond laser machining, and is washed, dried and processed through the silanization treatment; a PDMS valve surface which has the same fine structure with the template is copied by using a soft lithography method. The valve surface structure made by the invention is stable, has obvious characteristics of anticoagulation resistance and drag-reduction, effectively prevents the thrombosis, is hard to be damaged when being used for a long time, and is reusable without damage and deformation. Therefore, the mass production can be completed. In addition, the test method is simple and reliable.