The invention discloses albumen powder for tonifying spleen and losing weight, and a preparation method thereof. The albumen powder is prepared from the following raw materials in parts by weight: 1 to 2 parts of orange peel inner-layer white inner peel, 1 to 3 parts of white hyacinth bean, 1 to 3 parts of white kidney bean, 2 to 4 parts of exocarpium benincasae, 1 to 3 parts of poria cocos, 1 to 3 parts of rhizoma alismatis, 1 to 3 parts of grifola, 1 to 2 parts of rhizoma atractylodis macrocephalae, 0.5 to 1.5 parts of radix glycyrrhizae, 2 to 3 parts of semen cassiae, 0.3 to 0.7 part of folium sennae, 0.5 to 0.8 part of oat fiber, 0.3 to 0.5 part of apple fiber, 1 to 2 parts of folium nelumbinis powder, 1 to 3 parts of radix puerariae freeze-dried powder, and 3 to 5 parts of concentrated whey protein. The albumen powder for tonifying spleen and losing weight provided by the invention has the efficacy on effectively nourishing spleen and stomach, and invigorating spleen to remove dampness, is reasonable in nutritional supplement, ensures the nutritional requirement of a human body, meanwhile, is beneficial to reducing the acceptable daily intake of energy, achieves an effect on reducing blood glucose and losing weight, and is easy to assimilate, fine and smooth in taste, and mellow in flavor.