216 results about "Monilinia laxa" patented technology

The present invention features a novel use of processed ingredients from the Indian mulberry plant, and particularly a novel use of one or more processed Morinda citrifolia-based naturaceutical formulations comprising one or more of a processed Morinda citrifolia fruit juice, puree juice, oil or oil extract, dietary fiber, alcohol extract, etc., for inhibiting and preventing the overgrowth of Candida fungus and for treating Candidiasis and its associated symptoms.

A biochip for detecting the pathogenic funguses features that the DNA probes respectively for detecting one of 20 pathogenic funguses including Candida albicans, Aspergillus fumigatus, etc are immobilized on the glass plate, silicon chip, or high-molecular material.

The invention relates to a traditional Chinese medicine antibiotic skincare hand cleanser prepared from mixed materials of a traditional Chinese medicine extract, a surfactant, an antiseptic, glycerin, an essence and water. The traditional Chinese medicine extract is prepared from raw materials of, by weight: 35-45 parts of lightyellow sophora root, 15-25 parts of amur corktree bark, 15-25 parts of Chinese gentian, 5-15 parts of common cnidium fruit, and 5-15 parts of belvedere fruit. The raw materials are extracted by using water, and the density d of the obtained traditional Chinese medicine extract is 1.5-1.8g / ml. The traditional Chinese medicine antibiotic skincare hand cleanser provided by the invention has certain inhibitive effects against escherichia coli, staphylococcus aureus, and candida albicans, and provides certain preventive effects against eczema, skin pruritus, and the like. The hand cleanser is also advantaged in small dosage, high decontamination capability, good sterilization effect, and low irritation. The hands are delicate and not dry after washing. According to the invention, the formula of the hand cleanser is simple. With the hand cleanser, modern market requirements on naturalness, environment-friendliness, and high antibiotic efficiency can be satisfied.

The invention discloses a cow leather mat with an anti-bacterial function. The cow leather mat is characterized in that a grain side and a flesh side of the cow leather mat simultaneously comprises a nano-silver and isothiazolinone antibacterial agent; the inhibition zone of the nano-silver and isothiazolinone antibacterial agent to staphylococcus aureus, colon bacillus, bacillus subtilis, Aspergillus niger, blue mould, hair mould, cryptococcus neoformans, candida albicans is 43.28 to 68.84mm; the dry wipe resistance level is 4 to 5 level or 5 level; the wet wipe resistance level is 3 to 4 level or 4 level; and folding resistance fastness is 1 level. The invention also discloses a preparation method of the cow leather mat. The cow leather mat not only has good inhibit function to bacterium and fungus, but also has durable antibacterial property; the preparation method is skillful, the only thing to do is to add antibacterial treatment after a middle layer is coated, additional investment cannot be increased, the process is simple to operate, and the cow leather mat is applicable to industrial application.

The invention discloses ozonized borneol tea oil. The ozonized borneol tea oil comprises ozone, borneol and tea oil; the tea oil per 1L includes 30 to 50g of borneol; the total input of ozone in tea oil per 1L is controlled to be 13.5 to 20.0g under temperature of 25 to 30 DEG C and pressure of 0.5 to 1.5bar. According to the ozonized borneol tea oil, the raw materials are cheap and easy to be obtained, the antibacterial effect can be obviously improved, the effects of diminishing inflammation, relieving pain and sterilizing are great, the wound healing is effectively promoted, the recovery of patients is sped up, a patient can easily accept, the ozone can be stably and slowly released, escherichia coli, staphylococcus aureus, candida albicans and the like can be eliminated within a short time, and good effect is particularly shown on treating chronic wounds like diabetic foot and acute wounds.

The invention discloses a Bacillus subtilis strain and application thereof. The strain is named as Bacillus subtilis ZJU007 and preserved in the China general microbiological culture collection center (CGMCC) of Chinese Academy of Sciences on yard No.1 on Beichen West Road, in Chaoyang district in Beijing on September 3rd, 2010, and has the preservation number of CGMCC No.4140. A bactericidal substance generated by the strain of the invention has very strong inhibition effect on Candida albicans and has better bacteriostasis effect compared with common fungicidin. The bactericidal substance not only has very strong bacteriostasis effect on the Candida albicans and other yeast like fungi, and the like, but also has excellent effect on Aspergillus niger and other filamentous fungi, and meanwhile, has better bacteriostasis effect on escherichia coli and other bacteria.

The invention relates to application of an effective part of a cockroach extract in preparing a drug for inhibiting fungus growth, and particularly relates to application of an effective part obtained by refining a crude cockroach extract through macroporous adsorption resin in the aspect of preparing a drug capable of resisting fungal infection. The effective part is refined from a fresh or dried Periplaneta americana L. polypide product through alcohol and water extraction, macroporous adsorption resin column chromatography and alcohol solvent elution, and has an obvious inhibition effect on the growth activity of candida albicans and a fungus growth inhibition capacity 80 times higher than that of fluconazole and 5-fluorocytosine and 800 times higher than that of amphotericin. The effective part of the cockroach extract can be prepared into forms, such as a hydrogel, a frothy gel, a cataplasm, freeze-dried powder, a water aqua, an aerosol, a suppository, a film, an external liniment, an ointment and the like, and is used for preparing pharmaceutical preparations for preventing and curing fungal infection, medical appliances and daily-use chemical products.

Novel pharmaceuticals are described based on multivalent silver compounds containing Ag(II) or Ag(III) capable of killing pathogenic gram positive and negative bacteria, fungi and algae such as E. coli, Staphylococcus aureus and epidermidis, and Candida albicans. The efficacy of these compounds is enhanced by oxidizing agents such as persulfates. They can also be utilized to preserve pharmaceutical, cosmetic and chemical specialty products against these pathogens.

The invention discloses a bacteriostatic and anti-mite plant laundry detergent. The bacteriostatic and anti-mite plant laundry detergent comprises the following components in parts by weight: 0.5-6 parts of lotus extract, 0.1-5 parts of wild chrysanthemum flower extract, 0.1-0.5 part of anti-mite and bacteriostatic plant extract R301, 6-31 parts of an anionic surfactant, 12-43 parts of a nonionic surfactant, 0.06-1 part of a thickener and other auxiliaries and 40-60 parts of deionized water. The bacteriostatic and anti-mite laundry detergent which is obtained by blending the bacteriostatic and antiseptic plant raw materials such as the wild chrysanthemum flower and the lotus together is mild in property, environmental friendly, high in dirt-removing power, prone to rinsing and high in anti-bacteria and anti-mite effects. As being tested, the average antibacterial rates of the laundry detergent to staphylococcus aureus, escherichia coli and candida albicans are 99.89%, 100% and 99.93% respectively, and the anti-mite rate of the laundry detergent is 99.7%.

Compositions and methods for detecting and / or differentiating among Candida organisms, including C. albicans and C. dubliniensis, are disclosed. Exemplary methods involve screening a sample suspected of containing at least one or more Candida sp. for the presence or absence of a nucleic acid sequence specific for each such fungal pathogen. Some disclosed methods permit the rapid and simultaneous detection and identification of several fungal pathogens (e.g., up to 100 fungi) in a single sample.

The invention relates to traditional Chinese medicine antibacterial and nourishing bath foam, which is prepared by mixing traditional Chinese medicine extract, a surfactant, a preservative, peppermint oil, borneol, essence and water, wherein the traditional Chinese medicine extract with density (d) of 1.5-1.8 g / mL is obtained by extracting 25-35 parts by weight of radix sophorae flavescentis, 15-25 parts by weight of phellodendron bark, 25-35 parts by weight of gentian grass, 15-25 parts by weight of cnidium fruit and 15-25 parts by weight of glabrous greenbrier rhizome as raw materials with water as extracting liquid. The traditional Chinese medicine antibacterial and nourishing bath foam provided by the invention has certain bacteriostatic effects on Escherichia coli, Staphylococcus aureus and Candida albicans, has the effects of preventing eczema, skin pruritus, acariasis and the like, has the effects of dehumidifying, dredging joints, detoxifying and the like, and has certain nourishing action on the skin. The bath foam provided by the invention has simple formula, and can satisfy the natural, environmentally-friendly and efficiently antibacterial primary demands in the modern markets.

The present invention presents a method of preventing vertical transmission of an infectious disease comprising: (a) applying a photosensitizing composition to host tissues of birth canal of a mother during the intrapartum period; and (b) applying light to the host tissues after the step (a) at a wavelength absorbed by the photosensitizing composition so as to inhibit or eliminate infectious disease microorganisms that come into contact with the host tissues. The infectious disease may be caused by human immunodeficiency virus type 1, hepatitis B virus, hepatitis C virus, Group B Streptococcus, cytomegalovirus, Listeria monocytogenes, Chiamydia trachomatis, Escherichia coli, herpes simplex virus, Epstein-Barr virus, Toxoplasma gondii, human papilloma virus, and Candida.

The invention relates to a rapid detection method for candida albicans by loop-mediated isothermal amplification. Reagents used by the method comprises a loop-mediated isothermal amplification reaction solution, a Bst DNA polymerase and a color development reagent, wherein the reaction solution contains reaction buffer, dNTP, magnesium sulfate, an upstream inner primer 5-CACATTTTGGATAAGGTTCACCATT-ATAGAAACCTCAAGATTTCCGT-3, a downstream inner primer 5-TCGTGTTCGTGAAAGTGAAGATAAT-CTTTCTATCATCCAAATCGTAGA-3, an upstream outer primer 5-ACCGTTGATTTCCAATTCG-3, a downstream outer primer 5-TTAACTTGAGCCATGGAGAT-3, and glycine betaine. The method for detection of candida albicans comprises the steps of DNA extraction of the fungi, loop-mediated isothermal amplification of the candida albicans, and chromogenic detection. The method has the characteristics of rapidness, strong specificity, high sensitivity and low cost.

The invention relates to preparation for a pinus koraiensis phytoncide finishing agent, a fabric finished by same and a finishing method thereof. The formula of the finishing agent contains 10-40g / L of pinus koraiensis phytoncide microcapsule, 10-35g / L of chitosan cross-linking agent, 2-5g / L of organic silicon soft finishing agent and 1-3g / L of penetrant. The pinus koraiensis phytoncide finishing agent is prepared according to the steps of extracting pinus koraiensis phytoncide, preparing the pinus koraiensis phytoncide microcapsule, preparing the pinus koraiensis phytoncide finishing agent, bottling and packaging. The finishing agent is applied to the finishing of the cotton fabric. The cotton fabric has the antibacterial rate for staphylococcus aureus of above 98.2%, antibacterial rate for escherichia coli of above 92.3%, antibacterial rate for candida albicans of above 90.5%, deodorization rate of above 97.2%, mite-proof rate of above 90.6% and the reducing rate of sterilizing, deodorizing and mite-proof effects of below 10% after being cleaned for more than 20 times.

The invention relates to a kit, and aims at providing a kit used for detecting candida albicans in the intestinal tract by a fluorescence quantitative PCR method. The kit comprises a standard positive template and two primers of a specificity amplification candida albicans ITS zone used in the PCR amplification process, wherein the gene of a coded amplification product has the nucleotide sequence shown by SEQ ID NO: 3. The operation is simple and convenient and fast; the specificity is good, and the sensitivity is high; the detection based on nucleotide is not limited by culture conditions; the quantitative detection can truly reflect the situations of candida albicans permanent planting and infection in the intestinal tract; and high-flux sample detection can be implemented simultaneously. The kit can carry out fast and quantitative detection to the candida albicans in the intestinal tract, can replace the traditional diagnostic method of isolated culture which is used for a long time, and is suitable for being widely popularized and applied in clinical laboratory.

The invention relates to a novel broad-spectrum antifungal medicine compound, a broad-spectrum antifungal medicine composition, an application of the compound or the composition in the preparation of a broad-spectrum antifungal medicine, and an application of the compound or the composition in the preparation of a medicine used for treating severe invasive infection (comprising Candida krusei) caused by invasive aspergillosis and / or Fluconazole-resistant Monilia and / or severe infection caused by Scedosporium and fusarium. The novel broad-spectrum antifungal medicine compound and the broad-spectrum antifungal medicine composition have extensive and strong antifungal activity and better dynamic property and safety. For deep mycotic infection, the novel broad-spectrum antifungal medicine compound and the broad-spectrum antifungal medicine composition are better than the original voriconazole in the aspects of the antibiotic activity and the medicine resistance and is better than amphotericin B in the aspects of safety and effectiveness; and compared with the formerly applied voriconazole, Fluconazole, itraconazole and amphotericin B, the novel broad-spectrum antifungal medicine compound and the broad-spectrum antifungal medicine composition have reinforced medicine effect, less adverse reaction and good safety.

The invention discloses a traditional Chinese medicine preparation for treating candida albicans infection diseases. The traditional Chinese medicine preparation comprises the following ingredients in parts by weights: 6 to 10 parts of golden cypress, 6 to 10 parts of coptis chinensis, 6 to 10 parts of skullcap, 3 to 8 parts of cortex pseudolaricis, 3 to 8 parts of cortex dictamni, 3 to 8 parts of hibiscus syriacus, 3 to 8 parts of gallnut, 3 to 6 parts of fructus kochiae and 3 to 6 parts of fructus cnidii. The recipe of the traditional Chinese medicine preparation has the advantages that the cure rate on the chronic candida albicans infection diseases is high, the effect taking speed is high, the disease cannot easily recur after the cure, the patients have no pain, the treatment cost is low, and in addition, no toxic or side effect is caused on the body.

The invention discloses gynecological gel which comprises the following components in parts by weight: 2-5 parts of an aloe extract, 2-5 parts of a blackened swallowwort root extract, 4-8 parts of a helichrysum extract, 10-15 parts of a honeysuckle extract, 1-3 parts of a purslane extract, 2-6 parts of a centella asiatica extract, 0.05-0.2 part of a cation antibacterial agent, 5-8 parts of nonoxynol, 6-10 parts of menthol, 0.5-5 parts of hydroxymethyl cellulose, 0.1-0.5 part of methyl p-hydroxyphenylpropionate and 50-70 parts of purified water. The gynecological gel has a sterilization function on escherichia coli, staphylococcus aureus, candida albicans and the like, is capable of preventing harmful bacteria from propagation, is faintly acid, is capable of maintaining endovaginal acid-base balance and keeping private parts of females in healthy states, is free of irritation on vagina mucosa and is capable of gently protecting tender skin of the private parts, and thus people can feel comfortable and fresh.

The present invention features a novel use of processed ingredients from the Indian mulberry plant, and particularly a novel use of one or more processed Morinda citrifolia-based naturaceutical formulations comprising one or more of a processed Morinda citrifolia fruit juice, puree juice, oil or oil extract, dietary fiber, alcohol extract, etc., for inhibiting and preventing the overgrowth of Candida fungus and for treating Candidiasis and its associated symptoms.

The invention discloses a new Pseudomonas corrugate strain (P94 GMCC No.1895), which is characterized by the following: manufacturing relative HCN to prevent bacteria, proteinase and phospholipase and IAA; inhibiting partial plant pathogenic fungus (Botrytis cinerea, Ceratocystis fimbriata, Monilinia laxa, Magnaporthe grisea, Pythium aphanidermatum and Phytophthora capsici) and partial pathogenic bacteria (Pseudomonas syringae, Acidovorax avenae and Ralstonia solanacearum); accelerating the growth of tomato and cucumber to improve production by 22%-28%.

The invention provides a pseudomonas pseudoalcaligenes new bacterial strain MOB13, the preserving number of the strain is CGMCC No.2763, and the new bacterial strain can be used for producing IAA and prolease which are related to antibacterium. The new bacterial strain has plate inhibiting effect on parts of plant pathogenic fungis (such as ceratocystis fimbriata, fusarium.oxysporum f.sp.niveum, monilinia laxa and phytophthora capsici). Plate, potted plant and field experiment are used for testing the control effect of Pseudomonad MOB13 to Rhizoctonia cerealis, and the control efficiency is respectively 62.13% and 73.87%. The new bacterial strain MOB13 has good growth promotion effect for wheat, can promote the plant height of wheat to increase 34.97%, and leads the root length to increase 17.34%.

The present invention discloses a lysostaphin compounded preparation. Said preparation comprises bacteria-killing effective quantity of lysostaphin and lysozyme. Said lysostaphin compounded preparation has higher bacteria-killing effect as compared with single lysostaphin, not only has the strong bacteria-killing action for Gram-positive bacterium and Gram-negative bacterium, but also has the good effect for killing the fungi of Candida albicans and red trichophyton, etc. It has high bacteria-killing activity and stability, does not produce drug resistance, and has no toxic side effect.

The invention relates to a dairy cow breast disinfectant, and belongs to the fields of biomedicine and medicaments for agriculture and livestock. The organic dairy cow breast disinfectant is characterized by comprising the following raw materials in percentage by mass according to the formula: 0.25 to 1 percent of 99 percent glycerol, 0.25 to 1 percent of synthetic Chinese medicinal herb concentrate, and the balance of deionized water. The Chinese medicinal herb concentrate is prepared from extracts of honeysuckle, indigowoad leaf, Chinese violet, muskroot-like semiaquilegia root, atractylodes rhizome, folium artemisiae argyi, phyllanthus ruinaria, dandelion, sophora flavescens, glabrous greenbrier rhizome, fructus cnidii, patrinia and groundsel by cleaning, extraction, re-extraction of primary residue, synthesis, decolorization and concentration, and the density of the concentrate is more than or equal to 1.04g / mm<3>. The disinfectant is used for diminishing dairy cow breast inflammation caused by invasion of multiple microbes such as candida albicans, escherichia coli, streptococcus, microsporum, salmonella and shigella and controlling invasion of pathogenic microbes on breasts and mammary glands of dairy cows.

The invention discloses a traditional Chinese medicinal composition for curing vagina diseases such as animal womb inflammation, postpartum diseases and the like. The traditional Chinese medicinal composition comprises the following active ingredients by weight: 140 + / - 10.0g of folium eucalypti extract, 140 + / - 10.0g of lavender extract, 200 + / - 10.0g of thymol and 4 + / - 1g of borneol. The traditional Chinese medicinal composition may also comprise 550 to 600g of excipient. The traditional Chinese medicinal composition can be applied locally to act on an affected part directly and forms a high medicinal concentration locally for quick response; and the medicament effect lasts for a long time and flushing in wombs is avoided, so inflammation spreading caused by inflammation further inward spreading in the process of flushing is prevented and good curative effect is produced. The medicine is nonirritant, causes fewer allergic reactions and avoids medicinal residue in bodies of animals. The traditional Chinese medicinal composition can prevent and cure vagina diseases such as acute and chronic endometritis, vaginitis, trichomonad or candida vaginitis, retention of afterbirth, dystocia and the like of livestock animals, can eliminate lochia and ensures normal progenitive functions of delivering females.

The invention provides an external used medicine for dermatologic diseases, which is characterized in that phellodendron, lightyellow sophora root, common cnidium fruit, broom cypress fruit, pericarpium zanthoxyli and chloroxylenol are used as active medicine ingredients, and the invention is prepared by mixing the active medicine ingredients with assistant ingredients that are acceptable in preparing external used medicines, wherein, the weight proportions of the active medicine ingredients are as follow: 2-8 parts of phellodendron, 1-5 parts of lightyellow sophora root, 1-5 parts of common cnidium fruit, 1-5 parts of broom cypress fruit, 4-15 parts of pericarpium zanthoxyli and 0.1-5 parts of chloroxylenol. The medicine is a combination of traditional Chinese medicine and western medicine, with the sterilizing rate of over 99.9%, and can effectively sterilize diverse bacteria and fungi such as golden brown staphylococcus, colon bacillus, candida albicans, etc. The external used medicine has quick effect on dermatologic diseases, has high cure rate, few side effects and no drug resistance, and can cure both symptom and root diseases.

The invention provides an external medicament which cures dermatosis. The invention is produced by raw material drugs according to weight share as follows: 100 to 150 shares of wild chrysanthemum flower, 50 to 100 shares of Chinese lobelia, 35 to 75 shares of purple flower violet and 10 to 15 shares of China rose. The invention proceeds reasonable combination of natural plants with the function of bacterium restraining and sterilization and proceeds the craft operations such as extraction and refining according to modern Chinese traditional medicine production craftwork so as to produce antipoisoning products widely used. The invention has restraining effect on golden brown staphylococcus, colon bacillus and candida albicans. The invention is mainly used for restraining bacterium of furunculosis, carbuncle, malignant sore and varied nameless pyogenic infections caused by the golden brown staphylococcus and also can be used for curing the bite of poisonous insects.

The invention discloses a jute root extract with antibacterial activity and a preparation method thereof. The method relates to a comprehensive jute utilization technology, and is used for preparing extracts. The jute root extract serves as a natural antibacterial preservative and an antibacterial finishing agent, and belongs to the field of application of foods, medicaments and textiles. The method comprises the following steps of: washing jute root serving as a raw material with water; drying; grinding; extracting ethanol under ultrasonic assistance; concentrating under the reduced pressure; and adsorbing and purifying with a macroporous resin to obtain the jute root extract with high antibacterial activity. The antibacterial effect of the jute root extract is detected by using gram-positive bacterium staphylococcus aureus, bacillus subtilis, candida albicans and gram-negative bacteria escherichia coli as tested bacteria by an in-vitro bacteria inhibition zone method. By adopting the method, the jute root extract with antibacterial activity has best antibacterial effect on the staphylococcus aureus and bacillus subtilis, better antibacterial effect on candida albicans and good antibacterial effect on escherichia coli.

The invention discloses a Chinese herbal medicine formaldehyde scavenger and a preparation method thereof. The Chinese herbal medicine formaldehyde scavenger contains the following raw materials in parts by mass: 5-10 parts of fructus forsythiae, 5-10 parts of folium artemisiae argyi, 6-15 parts of cassia seeds, 10-15 parts of lonicera japonica, 5-15 parts of radix isatidis, 10-20 parts of herba artemisiae, 5-10 parts of herba houttuyniae, 3-6 parts of cassia barks, 3-10 parts of dried tangerine peels, 1-5 parts of radix sophorae subporstratae, 5-10 parts of aloe vera, 5-10 parts of taraxacum mongolicum, 5-10 parts of folium isatidis and 5-10 parts of mint leaves. According to the Chinese herbal medicine formaldehyde scavenger and the preparation method thereof, the production process is simple, the preparation cost is low, the produced Chinese herbal medicine formaldehyde scavenger can be used for remarkably lowering the concentration of formaldehyde in indoor air, and the removal efficiency reaches 90% or more; the durability is good, meanwhile, a good bactericidal effect can be achieved, and the rate of killing of staphylococcus aureus, Escherichia coli, black Bacillus subtilis variants and Candida albicans is 80% or more. Furthermore, the Chinese herbal medicine formaldehyde scavenger is non-toxic, nonirritant and readily-degradable.

The invention relates to a novel wide-spectrum bacterial strain Bacillus sp. AH-E-1 inhibiting clinical and plant pathogenic fungi, and an application thereof. The main content comprises: (1) Bacillus sp. AH-E-1 is a newly-discovered bacillus strain or subspecies; (2) Bacillus sp. AH-E-1 can produce anti-fungus substances after fermentation under appropriate conditions; (3) Bacillus sp. AH-E-1 can significantly inhibit 20 clinical pathogenic fungi such as aspergillus flavus, aspergillus fumigates, trichophyton rubrum, trichophyton mentagrophyte, candida glabrata, cryptococcus neoformans, and the like; (4) Bacillus sp. AH-E-1 can significantly inhibit 13 plant pathogenic fungi such as staphylococcus, magnaporthe oryzae, rhizopusstolonife, and the like. The invention provides an excellent novel anti-fungus substance producing bacterial strain which has the advantages of wide fungus-inhibiting spectrum, obvious effect, and the like.

The invention relates to a Polyrhachis vicina extractive and antifungal medical purpose thereof. Specifically, the invention relates to a traditional Chinese medicine Polyrhachis vicina extractive with function of controlling fungal infection diseases, and a preparation method and medical purpose thereof in preparation of antifungal drugs. The Polyrhachis vicina extractive provided by the invention is prepared by organic solvent immersion and extraction on dried bodies of Polyrhachis vicina. The extractive has significant activity on inhibiting the growth of Candida albicans, and can be prepared into tablets, granules, capsules, pills, an oral liquid, dripping pills, a coating agent, an external liniment, a film agent, an ointment, a spraying agent, an injection, a transdermal patch and an aerosol, and used in the preparation of medicines, daily chemical products or medical devices for prevention and treatment of fungal infections.