239 results about "Cholesterol cholelithiasis" patented technology

Disclosed is an expandable transluminal sheath, for introduction into the body while in a first, low cross-sectional area configuration, and subsequent expansion of at least a part of the distal end of the sheath to a second, enlarged cross-sectional configuration. The sheath is configured for use in the gastrointestinal system and has utility in the performance of endoscopic retrograde cholangiopancreatography (ERCP). The distal end of the sheath is maintained in the first, low cross-sectional configuration and expanded using a radial dilatation device. In an exemplary application, the sheath is utilized to provide access for a diagnostic or therapeutic procedure such as gallstone or pancreatic stone removal.

This invention also provides a method to prevent, control, and treata lipid metabolism disorder, a billary disorder, cardiovascular disease, obesity or an endocrine disorder by administering at least one agonist of guanalyte cyclase receptor either alone or in combination with a compound typically used to treat the disorder and or with an inhibitor of cGMP-dependent phosphodieasterases.

There is provided a method for controlling the movement of bile and / or gall stones in the biliary duct. The method comprises gently constricting (i.e., without substantially hampering the blood circulation in the tissue wall) at least one portion of the tissue wall to influence the movement of bile and / or gallstones in the biliary duct, and stimulating the constricted wall portion to cause contraction of the wall portion to further influence the movement of bile and / or gallstones in the biliary duct. The method can be used for restricting or stopping the movement of bile and / or gallstones in the biliary duct, or for actively moving the fluid in the biliary duct, with a low risk of injuring the biliary duct.

The invention discloses a new Chinese medicinal composition for treating the symptom of gallstones and a preparation method thereof. The Chinese medicinal composition mainly comprises the following raw material medicaments: pangolin scales, immature bitter orange, curcuma aromatica, green tangerine peel, chicken's gizzard-membrane, peach seed, safflower, common burreed rhizome, zedoary, rhizoma corydalis, frankincense, myrrh, dragon's blood, Chinese honeylocust spine, root of red-rooted salvia, sappan wood, dried lacquer, turtle shell, rhubarb, Chinese dwarf cherry seed, golden thread, honeysuckle, artemisia capillaries, longhairy antenoron herb, pantain seed, talc and Japanese climbing fern spore. The Chinese medicinal composition of the invention can be prepared into any common oral administration preparation according to the conventional method of Chinese medicinal preparations. The Chinese medicinal composition can improve symptoms such as pain, paroxysmal aggravation, abdominal distension, bitter taste, constipation, yellow urine, ictericsclera, yellow body and the like which are caused by gallstones obviously, call away the gallstones, bile duct stones and stones in intrahepatic bile ducts, and has the definite clinical curative effect and obvious curative effect on the treatment of cholecystitis. The Chinese medicinal composition has the advantages of low cost, no toxic or side effect basically and the like.

The invention provides a Chinese sausage containing dietary fibers and fish meat and a production method thereof, which can make up for the shortage of the current sausage market. The technical scheme is as follows: the weight percentage of the dietary fibers is 2 percent to 20 percent, the weight percentage of the fish meat is 10 percent to 40 percent, the weight percentage of livestock meat is 30 percent to 70 percent, the weight percentage of seasoning is 5 percent to 15 percent, and the rest is water. The Chinese sausage has functions, such as preventing constipation and intestinal diseases, eliminating heavy metals and radicals in the body, preventing cardiovascular diseases, diabetes and breast cancer, preventing and treating gallstone, reducing blood pressure and enhancing the immunocompetence of the human body.

The invention discloses an FXR receptor modulator, and a preparation method and an application thereof, belonging to the field of medicinal chemistry. The FXR receptor modulator with a structure characteristic as shown in a formula I in the specification or pharmaceutically-acceptable salts or stereoisomers or solvates or prodrugs thereof can bind with an FXR (i.e., NR1H4) receptor and is used as an agonist or a partial agonist of the FXR receptor, thereby being able to be applied to prevention and treatment of FXR mediated diseases, such as chronic intrahepatic or extrahepatic cholestasis, hepatic fibrosis caused by chronic cholestasis or acute intrahepatic cholestasis, or chronic hepatitis B, or gallstone, or liver cancer, or colon cancer, or inflammatory bowel diseases, etc., wherein a part of compounds specifically can reach an FXR-excited EC<50> of 100 nM or below, show good FXR agonist activity, have excellent application prospects, and provide a new medicine choice for clinical treatment of the FXR mediated diseases.

This invention also provides a method to prevent, control, and treata lipid metabolism disorder, a biliary disorder, cardiovascular disease, obesity or an endocrine disorder by administering at least one agonist of guanalyte cyclase receptor either alone or in combination with a compound typically used to treat the disorder and or with an inhibitor of cGMP-dependent phosphodieasterases.

This invention also provides a method to prevent, control, and treat a lipid metabolism disorder, a billary disorder, cardiovascular disease, obesity or an endocrine disorder by administering at least one agonist of guanalyte cyclase receptor either alone or in combination with a compound typically used to treat the disorder and or with an inhibitor of cGMP-dependent phosphodieasterases.

The invention relates to a health-care konjak rice glue ball and a preparation method thereof. The preparation method comprises the following steps: preparing rice glue ball powder; preparing stuffing; molding the stuffing; quick-freezing; rolling circles of the molded stuffing; packaging; and refrigerating. In the health-care konjak rice glue ball, the konjaku flour is utilized as a main raw material, the konjac glucomannan in the konjaku flour not only is an excellent water-soluble dietary fiber with low calorie, low fat and high cellulose, but also has an important regulating effect in nutritive equilibrium, functions of losing weight, relaxing bowel and regulating cholesterol metabolism, and obvious curative effects on diseases such as arteriosclerosis, gallstone, constipation, diabetes, obesity and the like, thus being a health-care food; lotus rhizome contains various nutritions, is rich in calcium, phosphonium, ferrum and multivitamins and has various functions of reducing fever and moistening the lung, strengthening the spleen and stimulating the appetite, reducing the blood pressure, arresting hemorrhage and the like, thus being a favorable tonic for the old, the young, women, children and weak patients; and sweet potatoes are rich in multivitamins, amino acid and dietary fiber which are essencial to a human body as well as various mineral substances such as calcium, ferrum and the like, are high in amylopectin content and can be easily digested and absorbed by the human body, thus being a health-care food.

The invention relates to a beverage containing water-soluble dietary alga fiber carrageenan. The invention has the following characteristics that: the beverage comprises the water-soluble dietary alga fiber carrageenan, sugar, fruit juice or food flavor, citric acid and water, the weight percentage of the water-soluble dietary alga fiber carrageenan ranges from 0.01 percent to 20 percent, the weight percentage of the sugar ranges from 0.0001 percent to 20 percent, the weight percentage of the fruit juice or food flavor ranges from 0.0001 percent to 40 percent, the weight percentage of the citric acid ranges from 0.0001 percent to 2 percent, and the rest is water. The beverage can prevent constipation and intestinal diseases, eliminate heavy metals and radicals in the body, prevent cardiovascular diseases, diabetes and breast cancer and gallstone, reduce blood pressure and enhance the immunocompetence of the human body. The beverage does not contain high-calorific-value ingredients such as protein and fat, belonging to a low-calorific-value functional beverage, and the beverage not only enriches Chinese food culture, but also greatly improves the physical health of people.

A piezoelectric micro-disruptor capable of disrupting a blockage both mechanically and vibrationally is presented. The micro-disruptor includes a rotor, a stator disposed about and contacting the rotor, a cutting element, and a flexible guide wire. In one embodiment, the stator is composed of a flexible cylinder with at least two piezoelectric elements attached thereto. Piezoelectric elements are electroded, wired to power leads within the flexible guide wire, and poled to function as an actuator. Expansion and contraction of the piezoelectric elements causes the flexible cylinder to wobble, thus driving the rotor and cutting element in a rotary fashion. In another embodiment, the stator is a piezoelectric cylinder with at least two electrodes attached separately thereto so as to contact and rotate a rotor assembly. Piezoelectric elements and cylinder are electrically driven so as to vibrate the stator, rotor, and cutting element. The present invention has immediate applicability within medical devices for the removal and disruption of an embolus, thrombus, kidney stone, gallstone, fatty deposit, or the like.

The invention relates to a dietary fiber and fish sausage and a production method thereof, which can fill the disadvantages of the conventional fish sausages in the current market. The invention adopts the technical scheme that the sausage comprises dietary fiber, fish and seasonings. The weight percentages of the dietary fiber, the fish and the seasonings are respectively 2-30%, 50-90% and 2-20%, and the rest is water. The sausage has the advantages of preventing constipation and bowel disease, removing heavy metals inside the body, removing free radicals, preventing cardiovascular disease, diabetes,and breast cancer, preventing and curing gallstones, lowering blood pressure and strengthening the human immune functions.

The invention discloses an application of hydroxyacetophenone and its derivatives in preparing drugs for curing cholelithiasis, which can enhance the excretion of bile and lower down the content of cholesterin and bilirubin in the bile, thus realizing the dual effects of bile expelling and lithiasis resolving. Therefore, the invention can be applied to treat lithiasis.

The present invention relates to compounds of formula I wherein R1, R2, R3, R4, R5, U, V, W, k and m are as defined in the description and claims, and pharmaceutically acceptable salts and / or pharmaceutically acceptable esters thereof. The compounds are useful for the treatment and / or prophylaxis of diseases which are associated with 2,3-oxidosqualene-lanosterol cyclase such as hypercholesterolemia, hyperlipemia, arteriosclerosis, vascular diseases, mycoses, parasit infections, gallstones, tumors and / or hyperproliferative disorders, and treatment and / or prophylaxis of impaired glucose tolerance and diabetes.

A nutraceutical formula and food-based medicinal composition is provided comprising homeopathic ingredients in combination with traditional herbal and nutraceutical ingredients for relieving the symptoms associated with presence or formation of kidney stones and gallstones. The formulation includes ingredients balanced in a synergistic manner to elicit complementary effects which both reduce the symptoms of kidney stones and gallstones and provide the potential to eliminate their occurrence in the body and prevent future recurrence. Methods of making and using core medicinal formulations and food-based compositions are also described.

The present invention relates to novel dihydroindole and tetrahydroquinoline derivatives and pharmaceutically acceptable salts and / or pharmaceutically acceptable esters thereof. The compounds are useful for the treatment and / or prophylaxis of diseases which are associated with 2,3-oxidosqualene-lanosterol cyclase such as hypercholesterolemia, hyperlipemia, arteriosclerosis, vascular diseases, mycoses, gallstones, tumors and / or hyperproliferative disorders, and treatment and / or prophylaxis of impaired glucose tolerance and diabetes.

The invention discloses a Chinese medicinal preparation for treating biliary tract system concretion, wherein the raw material herbs include (by weight portion) climbing fern spore4-6, blattbulume 2-4, nitrel 10-15, and oldenlandia 2-4, white alum 0. 5-1. 5, ligumaloes 0. 4-0. 6, Clematis chinensis 7-10, Os Sepiae 3-4, root of muskroot-like semiaqilegia 1. 5-2. 5, gentian root 2-4, borax 0. 8-1. 2,oriental wormwood 1. 5-2. 5, lysimachia christinae 5-7, curcuma root 2. 5-3. 5, Chinese angelica root 1. 5-2. 5, talcum powder 2. 5-3. 5 and radix salvia miltiorrhiza 1. 5-2. 5.

Catheter apparatus for performing diagnostic and therapeutic modalities in the biliary tree includes a catheter with multiple lumens. A first lumen is adapted to receive a guidewire and can serve as a transport lumen for contrast agent. A second lumen carries a cutting wire for performing a sphincterotomy. A third lumen can be used as an inflation lumen for a distally located balloon. Expansion of the balloon occludes a portion of the biliary tree and allows the catheter to sweep any gallstones through the sphincter of Oddi into the duodenum.

The long-term usage of AICR (5-aminio, 4-imidazole carboxamide riboside) to produce sustained metabolic and biological changes in mammals that overcome insulin resistance, i.e., increase insulin sensitivity, and result in benefits in diseases and conditions such as diabetes, hypertension, atherosclerosis, polycystic ovary syndrome and gallstones is described long-term usage of AICAR, particularly intermittent administration, e.g., three days per week, appears to have some of the positive effects of exercise, having an impact on the amount Of food consumed by a subject and resulting in reduced fat build-up and increase in muscle mass. Therefore, AICAR administration has a positive impact in reducing obesity. AICAR can also Prove useful in preventing or treating vascular diseases associated with hyperglycemia, high plasma levels of free fatty acids (FFA) and triglyceride, and insulin resistance by virtue of the fact that this agent activates fatty acid oxidation. Animal tests have Shown that chronic intermittent treatment with AICAR has not resulted in any noticeable toxic effects. AICAR and related compounds are activators of AMP-activated protein kinase (AMPK) and, furthermore, are effective at decreasing malonyl CoA levels in the animal.

The invention provides an oral administration traditional Chinese preparation for treating rhinitis, comprising one of the two groups of weight portion, group 1, biond magnolia flower 45-55, dahurian angelica root 45-50, pangolin scales 40-50, Ligusticum wallichii 45-55, cocklebur fruit 45-55, asarum herb 20-30, borneol 20-25, dragon's blood resin 18-25, artificial ox gallstone 20-25, group 2, silver flower 45-50, Chinese honeylocust spine 25-35, wrinkled gianthyssop 25-35, chrysanthemum flower 20-30, aristolochia stem 10-15, dandehon herb 45-55, herba schizonepetae 25-35, bupleurum root 20-30, peppermint 10-20, Chinese ephedra 15-25, calcium sulphate 55-65 and licorice root 25-35.

A general-purpose stone extractor is provided for removing gallstones, calculi or foreign bodies from the biliary tree, urinary tract, blood vessels and the like. The stone extractor is configured to enable catcher wires to be extracted and retracted from an outer sheath near to a stone by operating a push handle member, an elastic spring being installed between a proximal end of the outer sheath and the push handle member.

A Chinese patent medicine for treating esophagus cancer is prepared from 12 Chinese medicinal materials including human placenta, ox gallstone, musk, toad venom, etc.. Its advantages are the prescription with proper compatibility, high curative effect, and no toxic by-effect.

The invention discloses a medicine for treating gallstones. The medicine consists of the following Chinese herbal medicinal raw materials in parts by weight: 60g of lysimachia christinae hance, 45g of radix isatidis, 25g of mirabilite, 70g of fructus forsythiae, 40g of radix scutellariae, 15g of aristolochiae lignum, 7g of radix bupleuri, 15g of root of red-rooted salvia, 12g of rhizoma corydalis, 7g of nutgrass galingale rhizome, 12g of fructus toosendan, 20g of angelica, 7g of radix paeoniae alba, 5g of poncirus trifoliate, 25g of curcuma aromatica, 10g of fingered citron, 30g of radix astragali, 15g of chrysanthemum, 15g of felwort, 30g of serrate rabdosia herb, 7g of oriental wormwood, 27g of plantain herb, 10g of rhizoma alismatis, 16g of talcum, 5g of liquorice, 20g of lygodium japonicum, 25g of gardeniae, 15g of curcuma zedoary, 10g of amur cork tree bark, 20g of costus root, 22g of silybum marianum, 8g of poria cocos, 25g of dendrobe, 35g of hawthorn and 20g of pericarpium arecae. The medicine for treating gallstones has the advantages of being free from side effect, low in price, high in recovery rate, low in recurrence rate and rapid to become effective.

The invention discloses a medicine composition with anti-tumor and immune functions and a method of preparing the composition, a quality control method and the functions of the composition. The composition comprises artificial ox gallstone, honeysuckle flower, scolopendra, pangolin scale, toad venom, dandelion and other 18 traditional Chinese medicines; during preparation, the medicine composition fully displays the effective medicine by decocting, filtering, condensing, etc. different components; meanwhile, the invention also provides the quality control method of identifying the components and determining the content for the composition; the medicine composition of the invention has the effects of heat-toxin clearing, detumescence and removing blood stasis, strengthening body resistance, etc.; in addition, a plurality of tests prove that the medicine composition of the invention has anti-cancer and suppress cancer functions and is in particular applicable to the patients suffering from advanced gastrointestinal tract tumor; the medicine composition is free of toxicity, safety and reliable, can solve the side effect to the gastrointestinal tract brought by chemotherapy, can protect the hemogram and the immune function, has in particular obvious therapeutic effect to the patients suffering from stasis, and can become a novel anti-tumor Chinese traditional patent medicine.

The invention discloses a traditional Chinese medicine for treating gallstone and belongs to the technical field of traditional Chinese medicines. The Chinese medicine is prepared from the following raw materials: radix bupleuri, pericarpium citri reticulatae viride, pericarpium citri reticulatae, radix curcumae, rhizoma corydalis, endothelium corneum gigeriae galli, rheum officinale, immature bitter orange, corydalis tuber, scutellaria baicalensis, semen plantaginis, fructus aurantii, radix aucklandiae, mangnolia officinalis, toosendan fruit, polygonum cuspidatum, dandelion, oriental wormwood, poria cocos, radix pseudostellariae, radix paeoniae alba, honeysuckle, longhairy antenoron herb, trogopterus dung and liquorice. After the raw materials are combined, the traditional Chinese medicine has the effects of regulating qi-flowing for dehumidifying, dispersing stagnated liver qi for promoting bile flow, clearing away heat, dissipating blood stasis and invigorating spleen for promoting digestion, and has the advantages of simple treatment method, low cost and no side effects to the body on the aspect of treating gallstone. The traditional Chinese medicine has an inhibiting effect for gallstone formation, can reduce excessive aggregation of gallstone compositions in bile, and therefore reduces the risk of gallstone formation.

The invention provides a gynostemma pentaphyllum health-care tea capable of lowering blood sugar and blood pressure, which is prepared from the following raw materials in parts by weight: 10-50 parts of gynostemma pentaphyllum, 10-20 parts of Mangnolia officinalis, 10-20 parts of elsholtzia, 10-20 parts of Herba Lysimachiae, 10-20 parts of cogongrass rhizome, 10-20 parts of tuckahoe, 10-20 parts of radix salviae miltiorrhizae, 10-20 parts of Polyporus umbellatus, 10-20 parts of eupatorium, 10-20 parts of coix seed, 10-20 parts of mistletoe, 10-20 parts of Plantain seed, 10-20 parts of radix trichosanthis, 10-20 parts of radix scutellariae, 10-20 parts of Bighead Atractylodes Rhizome and 10-20 parts of corn silk. The gynostemma pentaphyllum has the effects of lowering blood fat, blood pressure and blood sugar, tranquilizing the mind, promoting sleep, resisting stress, ulcers and fatigue, prolonging the cell life, increasing the appetite, enhancing the resistance, relaxing the bowels, relieving asthma, relieving cough, eliminating hemorrhoids, reducing weight, treating asthenic symptoms, inhibiting gallstone from formation, controlling side effects of glucocorticoid, resisting aging and the like. Gynostemma pentaphyllum leaves used as the raw material are manually picked, and processed into the health-care tea by an old tea preparation technique and a traditional Chinese medicine decoction piece technique. The health-care tea has the advantages of green soup and subtle fragrance, tastes slightly bitter and mellow, and is suitable for long-term usage.

A process for externally culturing the natural ox gallstone includes collecting fresh ox gall, preparing the active components of gallstone, adding them collected ox gall, adding the active microbe composition, fermenting, preparing saturated solution of calcium oxide, preparing composite cholerythrin calcium, preparing ox gallstone, and examining quality.

The invention discloses a medicament for treating gallstone which is prepared from the following raw material herbs including (by weight ratio) lysimachia christinae 40-60, cape jasmine 5-20, oriental wormwood 40-60, rhizoma corydalis 5-20, rhubarb horsetails 2-10, sodium sulfate 2-20 and curcuma aromatica 5-20.

A Chinese medicine in the form of capsule, tablet, dripping pile, injection, etc for treating cholecystitis and cholelithiasis is prepared from capejasmine fruit through extracting in water or alcohol, separating and purifying by macroreticular resin.