An edible and / or chewable article of manufacture containing at least one
food grade substance having adsorption affinity towards at least one
dental plaque (
biofilm) constituent and capable of reducing and / or removing the oral
biofilm while present in the mouth. Particular articles of manufacture are chewing gums, sweets, candies, candy, and other nutritional bars,
ice creams, chocolates, confectionery and bakery / pastry products, honey, dairy products and beverages, and
oral hygiene products such as tooth pastes, oral gels and mouthwashes. A
chewing gum having a conventional
gum base and at least one
food grade active substance having adsorption affinity towards at least one
dental plaque (
biofilm) constituent (
bacteria and proteins and bacterial
cell-free enzymes) and capable of reducing and / or removing the oral biofilm while present in the mouth. Active substances include polysaccharides and non-toxic salts thereof, such as alginates,
chitosan, carboxymethylcellulose,
agar and
carrageenan, inorganic substances such as silica, hydroxyapatite and
calcium carbonate and proteins, particularly
gelatin and
lectin. The article of manufacture removes and / or for prevents or reduces
dental plaque (biofilm), and controlling oral, dental and periodontal diseases.