141results about How to "Safe and non-toxic" patented technology

The invention relates to a bioactive glass ceramic material. The bioactive glass ceramic material belongs to a Na2O-CaO-SrO-SiO2-P2O5-F system, and comprises the following components in percentage by weight: 12-45% of SiO2, 10-35% of P2O5, 25-48% of CaO, 5-15% of Na2O, 3.5-4.9% of SrO, and 1.5-2.1% of F; and the main compositions of a crystalline phase in the bioactive glass ceramic material are hydroxyapatite, tricalcium phosphate and calcium sodium phosphate. The invention also provides a preparation method of the bioactive glass ceramic material, which comprises a powder calcinating method, a high-temperature melting method, and a coprecipitation synthesis method or a sol-gel method. The invention further provides the application of the bioactive glass ceramic material in oral care products. The bioactive glass ceramic material and a conventional oral care product carrier or a transfer agent are prepared into oral care products such as toothpastes, mouthwash, tooth powder, tooth gel, chewing gum, and the like, and the bioactive glass ceramic material can achieve an effect of effectively preventing dentine hypersensitivity and promoting the surface remineralization of teeth in the process of teeth cleaning.

An antibacterial hydrophilic polyurethane foam medical dressing is prepared by mixing a component A and a component B according to a mass ratio of 0.5-1 to 3-1 and foaming, wherein the component A isan isocyanate terminated hydrophilic prepolymer; the component B is a functional foaming mixture formed by mixing 1-10% of a surfactant, 0.9-10% of a foam stabilizer, 0.1-10% of a cationic polymeric antibacterial agent and 70-98% of water. The antibacterial hydrophilic polyurethane foam medical dressing has the characteristics of simple preparation technology and strong operability. The prepared antibacterial hydrophilic polyurethane foam medical dressing has a good antibacterial property, maintains the antibacterial property thereof for a long time, has a good hydrophilic liquid-absorbing property and is a novel functional medical wound dressing.

The invention relates to seam beautifying glue, in particular to double-ingredient epoxy seam beautifying glue. An ingredient A is prepared from the following ingredients in percentage by weight: 60 to 90 percent of epoxy resin, 0 to 30 percent of plasticizers, 0 to 3 percent of anti-freezing agents, 0 to 15 percent of glitter powder, 1 to 10 percent of thixotropic agents, 0.01 to 1 percent of antifoaming agents and 0 to 20 percent of filling materials; an ingredient B is prepared from the following ingredients in percentage by mass: 65 to 95 percent of curing agents, 1 to 20 percent of thixotropic agents, 0 to 30 percent of plasticizers and 0 to 15 percent of glitter powder. The ingredient A and the ingreeinet B are respectively packaged after the preparation; the ingredient A and the ingredient B can be used after being uniformly mixed according to the weight ratio of 1:1. The construction operation is convenient; the advantages of safety, non-toxicity, wear resistance, waterproof performance, mildewproof performance, stain prevention, chemical medicine resistance, anti-cracking performance, fine crack resistance, yellowing resistance, rich color and the like are realized; the seam beautifying glue can be used as the seam beautifying glue by replacing the existing cement and can be used for performing color matching on ceramic tiles in different colors so as to achieve the decoration effect.

The invention relates to a tuberculosis gene vaccine assembled by a chitosan delivery system, which consists of chitosan and tuberculosis antigen encoding plasmids, wherein full-length genes of tubercle bacillus heat shock proteins HSP65 are inserted into the tuberculosis antigen encoding plasmids; and four T cell epitope genes EAST-6[189-228], Ag85A[369-405], CFP10[162-207] and Ag85B[420-459] from tubercle bacillus antigens are inserted into the HSP65 full-length genes. The invention also discloses application of the tuberculosis gene vaccine. By performing nasal drip of the gene vaccine on an immune mouse, the gene vaccine is proved to be capable of inducing response to special antibodies of a plurality of tuberculosis antigens, inducing killing response of locally strong tuberculosis special T cells of the whole body and lung mucous membranes, simultaneously inducing immunological response of Th1 which secretes high-level IFN gamma and have the effect which is obviously superior to the prior BCG vaccine, and is a superior vaccine for preventing and treating tuberculosis.

The invention discloses a toothpaste for children. The toothpaste for children comprises, by weight, 40-50% of a friction agent, 20-30% of a humectant, 2-5% of a foaming agent, 1-2% of a thickener, 0.01-0.1% of a sweetener, 1-2% of chlorophyll, 2-6% of a traditional Chinese medicinal composition, and the balance of water; and the traditional Chinese medicinal composition comprises, by weight, 10-30 parts of Chinese gall extract, 1-10 parts of tea polyphenols, 5-15 parts of Bletilla striata polysaccharides and 5-15 parts of propolis. The toothpaste for children can effectively prevent and treat oral ulcers, sore throat, periodontitis, gingivitis, caries prevention, bad breath and other oral and dental diseases, can promote the detoxification and swelling elimination repairing of oral injury tissues, is safe to use, is nontoxic, and has no irritating or carcinogenic property.

The invention discloses a rapid automatic extraction method and a reagent for paraffin section tissue nucleic acid. The reagent comprises a dewaxing agent, a protease solution, a lysate, a washing solution A, a washing solution B and an eluent. The method comprises the following steps: performing dewaxing rapidly by using the nontoxic dewaxing agent; after washing by ethanol, adding protease containing SDS and urea for cracking and digestion into liquid; transferring the liquid into an automatic magnetic bead extractor for extraction, performing cracking, magnetic bead adsorption, washing withthe washing solution A and the washing solution B and eluting with the eluent sequentially, and completing extraction of 32 or even 96 samples within a machine running time of about 30 minutes. According to the rapid automatic extraction method and the reagent for paraffin section tissue nucleic acid, after conventional first protease incubation is completed, the incubation dissolution system isheated to a high temperature and maintained for 3-5 minutes, a product is taken out and cooled to room temperature, protease is added to the reaction system, and tissue is completely dissolved and disappears after incubation for 10-30 minutes, obvious particles are absent, and the solution is clear.

The invention relates to a preparation method of an antibacterial and flame-retardant polyester fabric for luggage, comprising: adding a flame retardant to water, dispersing, adding water after adjusting the pH value, then adding an antibacterial finishing agent, stirring, and diluting with water to obtain an antibacterial and flame-retardant solution; Carry out two dipping and two rolling, then dry, bake, then wash with water, and dry, that is. The invention adopts high-efficiency flame-retardant finishing agent and antibacterial finishing agent to carry out antibacterial and flame-retardant multifunctional finishing on polyester luggage fabrics, and studies the antibacterial and flame-retardant effects of flame retardant, antibacterial finishing agent dosage, pre-baking temperature, baking temperature and time. influence to optimize the finishing process.

The invention relates to the technical field of protein removal for hericium erinaceus polysaccharide extracting solutions, in particular to a protein removal method for a hericium erinaceus polysaccharide extracting solution.The method comprises the steps that 1, a chitosan-acetic acid solution is prepared; 2, the hericium erinaceus polysaccharide extracting solution is mixed with the chitosan-acetic acid solution; 3, centrifugal treatment is carried out for the first time; 4, centrifugal treatment is carried out for the second time.The protein removal method for the hericium erinaceus polysaccharide extracting solution has the advantages of being safe, nontoxic, free of pollution, environmentally friendly, high in protein removal rate and low in polysaccharide losing rate, glycosidic bond breakage can be avoided, and then the polysaccharide structure and activity can be ensured.In addition, the protein removal method for the hericium erinaceus polysaccharide extracting solution has the advantages of being simple in treatment, easy to operate, low in production cost and applicable to large-scale production, and can be applied to production of relevant food health care products.

The invention discloses application of skin mucus extracts of andrias davidianus Blanchard to preparation of anti-breast cancer drugs. The application is characterized in that skin mucus is extracted through alkali liquor, and subjected to deproteinization and ion exchange and purified by gel chromatography to obtain vacuum dried extracts. In terms of mass fraction, the polysaccharide content is 38-41%, the protein content is 62-59%, polysaccharide proteins contain 6 monosaccharides of MaN, G1cUA, GaIUA, G1cN,G1c and Ga1, and the molecular weights of the proteins are 28KD. An inhibition test of human breast cancer cells MCF-7 is performed by adoption of an MTT (3-4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide) method, and after the human breast cancer cells MCF-7 are treated for 48 hours by the skin mucus extracts of andrias davidianus Blanchard of which the concentrations are more than 0.5 mg / ml, the inhibition rate of the extracts is more than 90%. Injections prepared from the skin mucus extracts of the andrias davidianus Blanchard are used for treating breast cancers, without side effects.

The invention discloses polyurethane primer, which is prepared by physically stirring and mixing 45 to 50 percent of E-03 (containing 5 percent of solid), 10 to 15 percent of polyurethane resin, 0.2 to 0.5 percent of catalyst, 15 to 20 percent of rust resisting pigment, 10 to 15 percent of titanium dioxide pigment, 5 to 10 percent of superfine barium sulfate, 10 to 15 percent of mixed solvent and 5 to 10 percent of polyurethane resin. The primer is a coating meeting environmental protection requirements, has good corrosion-resistance and rust resisting effects, high medium resistance, high quality and bright application prospect and contributes to environmental protection.

The invention relates to composite sponge and a preparation method of the composite sponge. The composite sponge is prepared from the following components in percentage by weight: 5%-15% of chitosan quaternary ammonium salt, 10%-23% of hyaluronic acid-RGD peptide, 25%-38% of gelatin, 15%-36% of PVA, and 5%-25% of glycerol. With the adoption of the technical scheme, the composite sponge and the preparation method have the beneficial technical effects that the antibacterial property of the novel chitosan sponge is improved, and the repairing for the surface of the wound is enhanced; the composite sponge containing the chitosan quaternary ammonium salt is simple in preparation method and low in cost, is safe and non-toxic, is obvious in antibacterial effect, can promote the cell growth, is beneficial for the repairing of the surface of the wound, is high in water absorption rate, and is suitable for industrial production.

The invention relates to a flower-shaped lactose loaded curcumin nano dry powder inhalant and a preparation method thereof, and belongs to the technical field of medical treatment. The flower-shaped lactose loaded curcumin nano dry powder inhalant consists of a drug carrier and curcumin solid lipid nanoparticles; the drug carrier is flower-shaped lactose; the flower-shaped lactose is prepared by performing a reaction on lactose monohydrate and citric acid; the flower-shaped lactose has a pore surface area of 30 plus and minus 7m2 / g, a pore volume of 0.7 plus and minus 0.3cm3 / g, a diameter peakvalue of 3.4, 5.6 and 12.4nm and an aerodynamic particle size of 2 to 4mum, and is adjustable in crude powder size; the curcumin solid lipid nanoparticles have an entrapment rate of 87.73%, a drug-loading rate of 7.72%, a particle size of 156.9 plus and minus 2.2nm, a polydispersity coefficient of 0.480 and an average Zeta potential of minus 24.8mV; and the dry powder inhalant is administrated toa respiratory system by a dry powder inhaler.