365 results about "Neurodermatitis" patented technology

The invention provides a Chinese herbal preparation for treating posirasis, which adopts 58 raw medicinal materials such as astragalus root, suberect spatholobus stem, Job stears, glabrous greenbrierrhizome, spreading hedyotis herb, barbed skullcap herb, motherwort herb and the like to manufacture oral agent and abrasive cleaner. The manufacturing method of the invention is as follows: 1. manufacturing by using the above raw material medicines into water-decocted liquid according to the conventional method; 2. manufacturing by using the water-decocted liquid which is manufactured in step 1 into oral liquid according to the conventional method; 3. drying, grinding and sieving the water-decocted liquid which is manufactured in step 1, and taking the throughs as powder; and 4. manufacturinginto powder tablets, granular formulation, medicinal granules or capsules by utilizing step 3 according to the conventional method. The powder and the abrasive cleaner can be manufactured by the following steps: 1. grinding the above raw material medicines; 2. sieving; and 3. taking the throughs, disinfecting and sterilizing to obtain the powder. The invention has high cure rate, low recurrence rate, can treat the primary and the secondary aspects at the same time, is safe and reliable, and can strengthen the autoimmunity. The invention mainly treats various types of posirasis, can treat neurodermatitis, comedo, acne and eczema concurrently, and has effects on lupus erythematosus, syphilis, lepra and skin cancer.

The present invention related to the use of a pharmaceutical composition which is essentially free of pharmaceutically active ingredients for the treatment of human skin, especially in the treatment of rosacea, acne, atopic dermatitis, contact dermatitis, perioral dermatitis, psoriasis or neurodermitis, as well as for prophylactic and / or cosmetic purposes.

The invention discloses a topical skin composition, the preparation method and application in the treatment of psoriasis, herpes zoster and neuro dermatitis, which comprises (a) an acceptable carrier in pharmacy, and (b) effective dose of water extract of raw herbal materials or extract of waterborne organic solution; wherein, the raw herbal materials comprises goldenrod, clove, radixstemonae, seed of cowherb, pseudolari cortex, pubescent holly, glycyrrhiza, dictamnus dasycarpus, angelica sinensis, safflower, gleditsia sinensis lam, uncaria, cynachum paniculatum and Chinese yam.

The present invention relates to compounds of the Formula (I), wherein X1 and X2 independently represent O, NH or S; R1 and R2 are independently selected from the group consisting of a C1-C30 hydrocarbyl group, an amino acid bonded via an amide bond or a peptide bonded via an amide bond each having up to 200 amino acids, the conjugated residue X1 or X2 in this case being NH, and hydrogen, both radicals R1 and R2 preferably not being H; and R3 is a residue selected from group consisting of —S—R6, wherein R6 is a C1-C30 hydrocarbyl group, at least one of R1 and R2 not being H when X1 and X2 are oxygen, —S—CH2—CH(NH2)(COOH) (cysteine-S-yl), a homologue or derivative (e.g. N-acetyl cysteine-S-yl) thereof, a peptide having up to 200 amino acids which contains at least one amino acid radical with a thiol group, preferably a cysteine radical, and is bonded via the thio sulfur, preferably via the cysteine sulfur (peptide-S-yl), coenzyme A which is bonded via a thiol group or fragments thereof, acyl carrier protein bonded via a thiol group, and dihydrolipoic acid bonded via a thiol group; and pharmaceutically acceptable salts thereof. The present invention also relates to the use of these compounds for preparing a drug, drugs containing the same and their use for the therapy of diseases such as autoimmune disease, NF-kappaB mediated diseases, psoriasis, psoriatic arthritis, neurodermitis, enteris regionalis Crohn, cardiac insufficiency, chronic obstructive pulmonary diseases and asthma and in transplantation medicine.

The invention relates to an oral traditional Chinese medicine for treating skin diseases. The oral traditional Chinese medicine is prepared from radix lithospermi, rhizoma smilacis glabrae, fructus gardeniae, cortex dictamni, common peony roots, radix scrophulariae, rehmanniae radix, isatis indigotica forts, radix sophorae flavescentis, lalang grass rhizome, flos sophorae, radix sileris, puncturevine caltrop fruits, red-rooted salvia roots, ligusticum wallichii, large-leaved gentian, processed polygonum multiflorum, Chinese angelica, white paeony roots and licorice roots. The oral traditional Chinese medicine is a pure traditional Chinese medicine prescription, reduces the recurrence rate of psoriasis and obviously improves the cure rate. In the invention, by mixing the Chinese angelica, the white paeony roots, the isatis indigotica forts and the licorice roots for use, the organism immunity can be enhanced greatly and the problem of recurrence of the psoriasis due to cold and pharyngitis can be solved. The oral traditional Chinese medicine has high effective rate to the psoriasis more than 98 percent and also has 100 percent cure rate to conventional skin diseases such as acne, cutaneous pruritus, pityriasis rosea, eczema, lichen planus, neurodermatitis, urticaria, seborrheic dermatitis, and the like.

The invention relates to a gel composition containing tacrolimus, which contains the tacrolimus and ingredients of a matrix, wherein, the ingredients of the matrix contain one or more of liquid polyethylene glycol, glycerin and propylene glycol, the content of the tacrolimus in the gel is 0.01 percent to 0.5 percent, and the weight ratio of the tacrolimus to one or more of the liquid polyethylene glycol, the glycerin and the propylene glycol is 1: (50 to 3000). The invention further relates to a preparation method of the gel composition of the tacrolimus and the application of the gel composition in the preparation of drugs for the treatment of atopic dermatitis, vitiligo, psoriasis, hormone-dependent dermatitis, intractable neurodermatitis, lupus erythematosus, alopecia areata and other diseases.

The invention relates to a Chinese medicament for treating skin diseases, which is prepared from radix rubiae, peach kernels, schizonepeta spike, snake slough, radix paeoniae rubrathe, Chinese angelica root, cogongrass rhizome, broom cypress fruit, siberian cocklebur fruit, dried rehmannia root, capsule of weeping forsythia, honeysuckle flower, dandelion, poria cocos, corktree bark, Chinese honey locust, root of ballon flower, motherwort, bitter apricot seed, ledebouriella root, the medicament can be prepared into any of the conventional oral administration preparation by employing the conventional methods for preparing traditional Chinese medicinal preparation.

The present invention relates to a Chinese medicine composition. In particular, it is a Chinese medicine composition for curing dermatosises of pruritus vulvae, psoriasis, neurodermatitis, allergic dermatitis, tinea pedis and beriberi, etc.

The invention discloses a Chinese medicinal preparation for treating various dermatoses, which is prepared from 21 Chinese medicaments such as cortex dictamni, erythrina indica lam and the like capable of promoting blood circulation by removing blood stasis and promoting circulation of qi and to relieve pain. The Chinese medicinal preparation has a unique formulation and precise and appropriate compatibility, has the effects of dispelling wind to nourish blood, removing dampness to relieve itching and cooling blood to remove toxic materials, has no bad adverse effects for clinical application, has a wide treatment range, overcomes the difficulties in grouping treatment of the dermatoses by using Chinese medicines and western medicines, and has significant curative effect of treating various dermatoses such as psoriasis, neurodermatitis, eczema, hives and acne which mainly causes epidermal hyperplasia, skin sichenification, inflammation of cuticula or a derma shallow layer, and vascular reactive and obstructive folliculus pili steatadenitis. After the prescription is taken for 7 days, itching disappears, lesion parts such as papula and maculopapule are gradually fade away, erythema and wheal disappears, exsudation is reduced, and squamae become thinner or fall off; after 14 to 21 days, the papula and the maculopapule disappears, the squamae are reduced, the sichenification disappears to achieve clinical healing; and after 28 to 35 days, skin lesions return to normal and are difficult to have a relapse.

The invention discloses the use of cannabinoid compounds or pharmaceutically acceptable salts thereof in the preparation of pharmaceutical compositions for the treatment of neurodermatitis, wherein the cannabinoid compounds can be selected from one of tetrahydrocannabinol, cannabinol, hypocannabinol and tetrahydrocannabinol, or the cannabinoid compounds can be selected from the group consisting of(1) a combination of tetrahydrocannabinol and tetrahydrocannabinol; (2) a combination of cannabinol and hypocannabinol; (iii) a combination of tetrahydrocannabinol and hypocannabinol; (4) a combination of cannabinol and tetrahydrocannabinol; (5) a combination of cannabinol, hypocannabinol and tetrahydrocannabinol; (6) a combination of tetrahydrocannabinol, hypocannabinol and tetrahydrocannabinol.

A Chinese medicine for treating psorinsis, ichthyosis, tinea, neurodermatitis, urticaria, eczema, flat wart, etc is composed of the orally taken capsules prepared from 19 Chinese-medicinal materials including dahurian angelica root, etc. the exterior-applied component A prepared from 6 Chinese-medicinal materials including cloves, etc. and the exterior-applied component B prepared from said component A and 14 Chinese-medicinal materials including dahurian angelica root, etc.

The invention relates to a medicament for treating neurodermatitis. The medicament comprises the following components: raw astragalus, densefruit pittany root-bark, belvedere fruit, lalang grass rhizome, puncturevine caltrop fruit, lightyellow sophora root, glabrous greenbrier rhizome, rehmannia root, tree peony bark, coix seed, scutellaria laterifolia, atraotydin, drgon's bones, oyster, garter snake, earthworm, leech, root poria, bitter orange and liquoric root. The medicament is prepared by the following steps of: frying the garter snake and the earthworm with soft fire respectively by adding yellow wine until the two medicaments are yellowish; putting talcpowder into a pot and frying until the talcpowder is hot; adding the leech, frying with soft fire, taking out, adding vinegar, soaking, and bailing out; and adding water into all the medicaments, decocting, taking decoction out, concentrating, and drying to prepare capsules. The medicament has the effects of clearing heat and promoting diuresis, detoxicateing, dispelling wind and arresting itching, invigorating spleen and tonifying vitality, and protecting liver and tonifying gallbladder and has 97 percent of effectual rate for treating the neurodermatitis.

The invention relates to a Chinese herbal medicine composition. A Chinese herbal medicine composition for treating dermatosis is prepared from the following raw materials: rhizoma smilacis glabrae, cortex dictamni, fructus kochiae, radix ampelopsis, cortex phellodendri, campsis grandiflora, cortex albiziae, paniculate swallowwort root, radix stemonae, rhizoma dioscoreae bulbiferae, rhizoma imperatae, common bluebeard herb, herba lobeliae chinensis, melastoma dode candrum lour, fructus xanthii, hibiscus rosa-sinensis, polygonum perfoliatum, eclipta alba, desmodium triquetrum, ilex rotunda, saxifrage, tuber fleeceflower stem, rhizoma dioscoreae, herba pogostemonis, linseed, maple leaf, roasted rhizoma atractylodis macrocephalae, fructus hordei germinatus, poria cocos and liquorice. The Chinese herbal medicine composition for treating dermatosis provided by the invention can quickly cure the dermatoses such as cutaneous pruritus, urticaria, neurodermatitis, psoriasis and the like.

The invention belongs to the technical field of medicaments and provides active ingredients of Chinese herbal medicine camptosorus sibiricus and an extraction method and use of the same. The extraction method comprises a water extraction method, an alcohol extraction method, a macroporous resin purification method and a solvent extraction method. The main active ingredients of an extract obtained by the method are total flavonoids, total momordica saponins and total organic acids, wherein the content of the total flavonoids is 1 to 35 percent, the content of the total momordica saponins is 1 to 25 percent and the content of the total organic acids is 1 to 3 percent. The invention also provides a method for preparing the camptosorus sibiricus into a proper formulation directly or by mixing with solid or liquid commonly used for preparations of the type in pharmaceutics. The active ingredients of the camptosorus sibiricus and the preparation thereof have functions of treating thromboangiitis obliterans, nephritis, traumatism and bleeding, metrorrhagia, neurodermitis, hemiplegia caused by cerebral embolism and diabetes-related complications. The extraction method is simple, easy to implement and low in cost. And the extract obtained is free from toxic and side effects.

The invention belongs to the field of traditional Chinese medicine compositions, and particularly relates to a traditional Chinese medicine composition for treating a skin disease and a preparation method thereof. The traditional Chinese medicine composition is prepared from, by weight, 3-5 parts of cortex pseudolaricis, 1.5-3.5 parts of radix et rhizoma rhei, 7-10 parts of cortex moutan, 8-15 parts of fructus kochiae, 7-10 parts of oriental variegated coralbean bark, 7-10 parts of coptidis rhizoma, 8-15 parts of cortex dictamni, 7-10 parts of cortex phellodendri, 7-10 parts of cortex meliae, 7-10 parts of radix scutellariae, 8-15 parts of fructus cnidii, 8-15 parts of radix sophorae flavescentis, 4-6 parts of salicylic acid, 8-12 parts of benzoic acid, 0.6-0.9 part of phenol, 4-6 parts of borneol, 4-6 parts of menthol crystals, 4-6 parts of dried alum and 4-6 parts of glycerin. According to the traditional Chinese medicine composition for treating the skin disease, the course of treatment is short, the effect is quick, the cause of a disease can be eliminated, relapse is not prone to occurrence, no toxic or side effect exists, and psoriasis, various fungal infections, eczema, seborrheic dermatitis, rhagadia of hands and feet, palmoplantar pustulosis, pityriasis rosea and neurodermatitis can be radically treated.

The present invention relates to specific and markedly improved pre-mRNA trans-splicing molecule (RTM) molecules which are designed to correct specific genes expressed within cells to be targeted, and which are associated with epidermolysis bullosa, cystic fibrosis, pachyonychia congenital, and psoriasis or neurodermitis, as well as cancers of the skin. In particular, the RTMs of the present invention are genetically engineered to interact with a specific target pre-mRNA expressed in cells to be targeted so as to result in correction of genetic defects or reprogramming of gene expression responsible for a variety of different skin disorders.

The invention relates to an external medicament composition for treating skin diseases, which is characterized in that the composition is prepared from the following raw materials in weight portion: 50 to 300 portions of Chinese mugwort leaves, 10 to 60 portions of mint, 10 to 80 portions of dittany bark, 10 to 60 portions of radix salviae miltiorrhizae, 10 to 60 portions of radix scutellariae and 10 to 50 portions of herba schizonepetae. The preparation method adopts the prior traditional Chinese medicine preparation technique, and the external medicament composition can be prepared into external location, liniment, ointment, spraying agent, and the like suitable to be used clinically. In the invention, the traditional Chinese medicine has the efficacies of clearing away heat and expelling the wind, removing dampness to relieve itching, reducing tumescence, and the like, and is suitable for symptoms such as pruritus caused by allergic skin diseases such as hives and the like, and allergic dermatitis, neurodermitis, and the like. Through clinical observation, the external medicament composition has the advantages of short treatment time, quick symptom relieving, good curative effect, safety, no toxic and side effects, and no irritation to skin.

The invention relates to a Chinese medicinal composition for treating skin diseases. The Chinese medicinal composition is prepared by stir-frying various Chinese herbal medicines such as phellodendron, baical skullcap root, manchurian wildginger, schizonepeta spike, bulbus fritilariae, golden larch bark, sulphur, realgar, toad venom, musk, mint rice, plant soot, salicylic acid and the like over slow fire, grinding accurately, mixing with badger fat, antelope oil and the like, grinding again and extracting. The Chinese medicinal composition can remove abnormal phlegmatic temperament, bile fluid and sepsis and relieve swelling and itching, and is used for treating parapsoriasis guttata (psoriasis), tinea manuum, tinea corporis, tinea pedis, tinea versicolor, intractable dermatitis, neurodermatitis, fungal skin diseases, leuconychia, purulent skin diseases, facial pityriasis, pityriasis rosea, seborrheic dermatitis, prurigo nodularis, scabies, eczema, herpes, acnes and the like.

The invention discloses an application of nocardia rubra cell wall skeleton (N-CWS) in preparation of drugs for treating skin lesions, which comprise at least one of eczema, neurodermatitis, non-specific dermatitis, atopic dermatitis, and psoriasis. N-CWS is used to treat skin diseases including eczema, neurodermatitis, non-specific dermatitis, atopic dermatitis, and psoriasis, can effectively relieve the symptoms of lesions such as exudation, swelling, red spots, toughened epidermis, lichenification, scaling, itching, and the like, reduces the skin damage caused by scratching and chronic friction, and finally improves and cures the skin diseases.

The invention provides an externally-applied traditional Chinese medicine, which comprises the following active ingredients in percentage by weight: 0.1 percent of menthol, 0.05 to 0.15 percent of triclosan, 0.1 percent of bronopol and the balance of traditional Chinese medicine extract. The traditional Chinese medicine extract is prepared from 11 traditional Chinese medicines such as lightyellow sophora root, baical skullcap root, amur corktree bark and the like. The externally-applied traditional Chinese medicine has good bacteriostasis, itching relieving and anti-inflammation effects and can be used for treating damp-heat and damp (heat) toxic diseases in traditional Chinese medical science such as skin itch, neurodermatitis, urticaria, eczema, tinea manus and pedis, cervical erosion, vaginitis, morbid leucorrhea and the like. The invention also provides a preparation method of the externally-applied traditional Chinese medicine.

The invention relates to a traditional Chinese medicine composition for treating neurodermatitis. The traditional Chinese medicine composition is prepared by desert asparagus, linearleaf thustle, periostracum cicada, apiary, white paeony root, myrobalan, Chinese-date, salix chienii, centipede, and black bean peel. The traditional Chinese medicine composition can be clinically applied to treating the neurodermatitis.

The invention relates to an external use ointment used for treating dermatitis and a preparation method thereof. An effective compound of the external use ointment comprises following raw materials: caragana microphylla, sundew, alternanthera sessilis, convolvulus arvensis, excoecaria sebifera, acronychia leaf, wing nut leaf, kazinoki broussonetia, calamint, gingium verum, vitex trifolia, ferb of desertliving asparagus, chenopodium album seed, mosla scabra, fruit of siberian nitraria and lantana camara. The external use ointment has efficacies of clearing heat and removing toxicity, eliminating dampness and relieving itching, and coursing wind and nourishing blood; and has significant effects on treatment of allergic dermatitis, atopic dermatitis, neurodermatitis, seborrheic dermatitis and dermatitis medicamentosa; possesses excellent curative effects on common dermatitis diseases such as erythema, papule, rahagades, desquamation, small abscess, pruritus, tenderness and burning heat sensation; and is capable of killing bacteria on human skin surface rapidly and efficiently, removing corrupted materials, promoting optimization and growth of epidermis cells effectively, enhancing plastid of epidermis cells, and helping damaged human body to recover rapidly.

The invention discloses a traditional Chinese medicine for treating neurodermatitis, which is prepared from field bindweed, plumbagella, broom cypress fruit, camptosorussibiricus Rupr., coix seed, elsholtzia cypriani, keel, laminaria polygonatum, bamboo shavings, equisetum, dodder and licorice, and can be clinically used for treating neurodermatitis.

The invention discloses a traditional Chinese medicine composition for treating skin diseases. The traditional Chinese medicine composition is a preparation prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-20 parts of cortex dictamni, 10-20 parts of radix sophorae flavescentis, 2-5 parts of creat, 5-15 parts of rhizoma atractylodis, 10-20 parts of radix stemonae, 5-15 parts of pericarpium zanthoxyli, 10-20 parts of radix rehmanniae, 10-20 parts of radix ophiopogonis, 10-20 parts of radix paeoniae alba, 10-20 parts of cortex lycii radicis, 5-15 parts of tribulus terrestris, 5-15 parts of schisandra chinensis, 5-15 parts of angelica and 10-20 parts of ledebouriella seseloides. The traditional Chinese medicine composition disclosed by the invention is exact in curative effect, as shown in clinical verification, the traditional Chinese medicine composition is remarkable in curative effect, reliable in action, mild in medicine property and free of side effect, and the traditional Chinese medicine composition can used for treating such skin diseases as cutaneous pruritus, urticaria, neurodermatitis, etc. When being used for curing cutaneous pruritus, the total effective rate can be greater than 90%.

The invention relates to external traditional Chinese medicine liquor for treating psoriasis. The external traditional Chinese medicine liquor comprises the following components: solidago decurrens, cortex pseudolaricis, the tuber of stemona, cortex dictamni, radix sophorae flavescentis, golden cypress, coptis chinensis, scutellaria baicalensis, fructus cnidii, fructus kochiae, divaricate saposhnikovia root, radix bupleuri, clove, radix stemonae, borneol and 75 percent of medicinal alcohol. The traditional Chinese medicine liquor can rapidly kill stubborn fungi and bacteria, eliminate skin infection, is applied to treating psoriasis of various types as well as neurodermatitis, tinea cruris, athlete's foot, fungal infection of the hand and ringworm of the nails, is wide in drug source, low in cost, simple in preparation method, convenient to use, is harmless to the human body, does not cause pain and does not have any toxic or side effect, and no scar is left after medication healing.

The strong antipruritic pill for treating obstinate pruritus is prepared with black-tail snake, scorpion, centipede, cocklebur fruit, cnidium fruit and other over twenty kinds of Chinese medicinal materials, and through sorting, washing, stoving, decocting, crushing, making pill, sterilizing and other steps. The present invention has the functions of dispelling wind evil, eliminating itching, cooling blood, eliminating toxic matter, activating blood circulation, dredging meridian and nourishing skin. It is used to treat obstinate pruritus and various dermatosis, including chronic urticaria, chronic eczema, neurodermatitis, tinea, etc.

The invention relates to a Chinese medicine for treating neurodermatitis which consists of Chinese herbal medicines: raidx astragali, radix codonopsitis, yam, angelica, lotus seed, pearl barley, herba schizonepetae, common cnidium fruit, fructus arctii, fructus kochiae and cicada ecdysis. The Chinese medicine has a reasonable formula, can activate blood circulation, dissipate stasis, dredge collaterals, relieve itch, effectively improve the symptom of neurodermatitis, achieve the aim of curing symptoms and root causes and has remarkable curative effect.

The invention provides an itching-relieving washing medicine bag and a preparation method thereof, wherein the washing medicine bag is prepared from the following main materials in parts by weight: 20-30 parts of cortex pseudolaricis, 20-30 parts of radix stemonae, 10-20 parts of dried alum, 8-15 parts of fructus kochiae, 8-15 parts of fructus cnidii, 8-15 parts of fructus xanthii, 10-15 parts of hydnocarpus anthelmintica, 5-10 parts of pepper seeds, 10-20 parts of radix sophorae flavescentis, 10-20 parts of bark of himalayan coralbean, 10-20 parts of senecio scandens, 8-15 parts of purslane, 10-20 parts of tooth soap, 8-15 parts of folium artemisiae argyi, 8-15 parts of lithospermum, 8-15 parts of liquidambar formosana hance, 10-20 parts of calamine and 8-15 parts of mint. The itching-relieving washing medicine bag disclosed by the invention has effects of clearing heat and expelling damp, inhibiting bacteria and killing insects, diminishing inflammation, moistening skin, softening skin and promoting blood circulation, is not only convenient, but also is safe and environmentally friendly, and almost suitable for all crowds. Moreover, the itching-relieving washing medicine bag has remarkable treatment effect on pruritus skin diseases such as chronic eczema, hand-foot tinea corporis, scabies, miliaria, neurodermatitis, prurigo nodularis, amyloidosis, pruritus vulvae, urticaria papulosa, and the like, and especially has effects of getting twofold results with half the effort for the itching of thick skin which cannot be permeated by external-use ointment.

The invention provides a pure Chinese traditional medicine preparation for treating psoriasis and multiple skin diseases. The pure Chinese traditional medicine preparation is prepared from the following 21 Chinese traditional medicinal materials: honeysuckle flowers, cortex phellodendri chinensis, flos chrysanthemi indici, glabrous greenbrier rhizome, common ducksmeat herb, yam rhizome, radix rehmanniae, zaocys dhumnade and the like. The pure Chinese traditional medicine preparation provided by the invention has the effects of dispelling wind and nourishing blood, removing dampness to relieve itching, removing pathogenic heat from the blood and toxic materials from the body and supporting the healthy energy, has good treatment effects on the allergic reaction, epidermis proliferation cornification, lichenification, vascular inflammation and hair follicle and sebaceous gland blockage, such as the psoriasis (psora), leucoderma, neurodermatitis, dermatitis, eczema, urticaria, irritability, rubella, comedo, acne and verruca plana, is wide in clinical application treatment range without toxic and side effects, and can not injure the organs and functions of a human body and enhance the physique and the immunity of the human body even if being taken for a long time. A medicament prepared through a preparation method of the pure Chinese traditional medicine preparation is high in dissolution rate and higher in stability.