139results about How to "Eliminate infection" patented technology

The present invention relates to a method of forming shape-retentive and shape-conforming aggregate wound dressings and biomaterials composed of gel nanoparticles and wound or bodily fluid in which the aggregates are held together by non-covalent bond physical forces such as, without limitation, hydrophobic-hydrophilic interactions and hydrogen bonds. The method comprises introducing a dry powder of gel nanoparticles to a wound site in which the nanoparticles absorb some of the blood or wound exudate and coalesce in situ into the claimed shape-retentive aggregate dressing. The method also comprises introducing the dry nanoparticle powder in or on a wet bodily tissue in vivo to form the claimed shape-retentive biomaterial. In addition, the method also comprises incorporating biomedical agents to produce medicated aggregate dressings or biomaterials for a variety of medical applications. This invention also relates to uses of the method of formation of the shape-retentive aggregates of gel nanoparticles.

Methods have been developed for incorporation of a peracid compound into or on wound application matrices, such as bandages or dressings, and other matrices which will favorably impact wound healing and help eliminate microbial infection. The peracid compound comprises a base compound that is metabolically pertinent to wound healing, the oxidized form of the base compound (a peracid), and an appropriate oxidizer, such as hydrogen peroxide. In addition, other excipients with wound healing potential, such as esters of the base compound, may be added to the peracid compound. The combination peracid-wound application matrices can be used to disinfect and heal various wound types with designed time release of the peracid compound.

Alterations of certain metabolite concentrations and fluxes that occur in response to viral infection are described. Host cell enzymes in the involved metabolic pathways are selected as targets for intervention; i.e., to restore metabolic flux to disadvantage viral replication, or to further derange metabolic flux resulting in “suicide” of viral-infected cells (but not uninfected cells) in order to limit viral propagation. While any of the enzymes in the relevant metabolic pathway can be selected, pivotal enzymes at key control points in these metabolic pathways are preferred as candidate antiviral drug targets. Inhibitors of these enzymes are used to reverse, or redirect, the effects of the viral infection. Drug candidates are tested for antiviral activity using screening assays in vitro and host cells, as well as in animal models. Animal models are then used to test efficacy of candidate compounds in preventing and treating viral infections. The antiviral activity of enzyme inhibitors is demonstrated.

The invention relates to nanoliposome human papillomavirus (HPV) resistant and gynecological inflammation pathogen resistant specific complex IgY and a combined preparation for the same. Laying poultry is preferred to respectively prepare laying poultry for immunity of tumor somatic cells, viral protein complex antigens, gene recombination protein antigens and bacterial virus complex antigens; and human papillomavirus resistant special IgY and gynecological inflammation pathogen resistant specific IgY undergo affinity chromatography and purification and are converted into nanoliposomes, and then the nanoliposome special complex IgY is prepared. The nanoliposome human papillomavirus (HPV) resistant and gynecological inflammation pathogen resistant specific complex IgY and the combined preparation for the same have the advantages that: the nanoliposome technology is applied to increase the infiltration capacity and the prolongation effect and improve the curative effect. The nanoliposome human papillomavirus (HPV) resistant and gynecological inflammation pathogen resistant specific complex IgY and the combined preparation for the same can be prepared into various vaginal spraying agents, other spraying agents, lotion, gel, capsules, suppository, vaginal membranes, tablets, effervescent tablets, ointment, cream and so on. The nanoliposome complex IgY can infiltrate into a vagina mucosa to effectively remove HPV viruses and gynecological inflammation pathogens which are absorbed on the vaginal surface layer and in the vagina mucosa, is absorbed through the vagina mucosa and enters into the body to give play to the functions of prevention and treatment, and also can effectively prevent recrudescence.

The invention discloses a non-invasive arrhythmia treatment system, which comprises an imaging device, a processing device and a gathered energy transmission device. The imaging device is used for imaging an object to be treated to construct three-dimensional heart and body models of the object to be treated. The processing device comprises a body surface electric signal acquisition module, an electric activity computation module and an arrhythmia determination module. The body surface electric signal acquisition module is used for acquiring body surface electric signals detected by a plurality of electrodes which are placed at a plurality of positions on a body surface. The electric activity computation module is used for computing electric activities in the internal three-dimensional space of the heart through an inverse problem based on the acquired body surface electric signals and the three-dimensional heart and body models. The arrhythmia determination module is used for determining at least one origin position of arrhythmia at least based on the electric activities in the internal three-dimensional space of the heart obtained through computation. The gathered energy transmission device is used for transmitting gathered energy to the determined origin position to ablate cardiac muscle tissues at the origin position.

The invention belongs to the field of food processing and discloses a pinenut oil pinolenic acid microcapsule and a preparation method of the microcapsule. The pinenut oil pinolenic acid microcapsule has a weight reduction function and can reduce cholesterol (TC) and triglyceride (TG) and increase high density lipoprotein (HDL). The preparation method comprises the following preparation steps of: extracting pinolenic acid, preparing a core material solution, preparing a wall material solution, and encapsulating a microcapsule. By adopting the preparation method disclosed by the invention, the extraction rate of the pinolenic acid from pinenut oil is more than 70%, the pinenut oil pinolenic acid which is easily oxidized is microencapsulated to effectively prolong the quality guarantee period, and the encapsulation rate is more than 85%.

A composition for modulating cytokines to regulate an inflammatory or immunomodulatory response. The composition can include at least one of rosehips, blueberry, blackberry, elderberry, cranberry, rosemary, clove, feverfew, nettle root, artichoke, reishi mushroom, olive extract, green tea extract, grape seed extract, resveratrol, Aframomum melegueta, boswellia serrata extract, boswellia forte, ipriflavone, tocotrienols, evening primrose oil, INM-176, borage oil, krill oil, at least one type of xanthophyll (e.g., astaxanthin), green coffee extract and ferulic acid. Specifically, a composition of the invention can include: rosehips and at least one of blackberry, blueberry, elderberry, and optionally krill oil; or rosehips, resveratrol and at least one of Aframomum melegueta and astaxanthin. Based on the cytokine modulation and cytokine response inhibition of the composition, it can be used to regulate an immunomodulatory and / or inflammatory response, and subsequently treat diseases and / or abnormal conditions associated with inflammatory response, for example, cardiovascular conditions, arthritis, osteoporosis and Alzheimer's disease.

The invention relates to external traditional Chinese medicine liquor for treating psoriasis. The external traditional Chinese medicine liquor comprises the following components: solidago decurrens, cortex pseudolaricis, the tuber of stemona, cortex dictamni, radix sophorae flavescentis, golden cypress, coptis chinensis, scutellaria baicalensis, fructus cnidii, fructus kochiae, divaricate saposhnikovia root, radix bupleuri, clove, radix stemonae, borneol and 75 percent of medicinal alcohol. The traditional Chinese medicine liquor can rapidly kill stubborn fungi and bacteria, eliminate skin infection, is applied to treating psoriasis of various types as well as neurodermatitis, tinea cruris, athlete's foot, fungal infection of the hand and ringworm of the nails, is wide in drug source, low in cost, simple in preparation method, convenient to use, is harmless to the human body, does not cause pain and does not have any toxic or side effect, and no scar is left after medication healing.

Methods have been developed for incorporation of a peracid compound into or on wound application matrices, such as bandages or dressings, and other matrices which will favorably impact wound healing and help eliminate microbial infection. The peracid compound comprises a base compound that is metabolically pertinent to wound healing, the oxidized form of the base compound (a peracid), and an appropriate oxidizer, such as hydrogen peroxide. In addition, other excipients with wound healing potential, such as esters of the base compound, may be added to the peracid compound. The combination peracid-wound application matrices can be used to disinfect and heal various wound types with designed time release of the peracid compound.

An antibacterial lotion for treating tinea manuum, tinea pedis, sweat foot, smelly foot, and rhagas of hand or foot is prepared from 7 Chinese-medicinal materials including forsythia fruit, ledebouriella root, flavescent sophora root, senecio, etc through crushing, immersing in aged vinegar for 5-15 days, and filtering.

The invention provides a segmented copolymer nano-composite antibacterial material and a preparation method and application thereof. By the utilization of a coupling agent having 2 isocyanates with different activities, 3-hydroxybutanoic acid and 3-hydroxyvalerate copolyester (PHBV) are synthesized with polyethylene glycol (PEG) to obtain a PEG-PHBV-PEG amphiphilic triblock copolymer, which is used as a base material to be self-assembled with a nano-antibacterial agent to obtain the segmented copolymer nano-composite antibacterial material. Controllable synthesis and regulation of antibacterial properties of the segmented copolymer are realized by the method. Number-average molecular weight of the obtained segmented copolymer is between 0.35-13 thousand, and molecular weight distribution is relatively narrow. The segmented copolymer nano-composite antibacterial material has antibacterial and antimicrobial dual functions. Antibacterial effect and bactericidal effect are remarkably raised. A micelle coated nano-antibacterial agent is dispersed uniformly, is stable in a water phase, has good cytocompatibility and has a wide application prospect.