42 results about "Erythroplakia" patented technology

The invention provides a Chinese herbal preparation for treating posirasis, which adopts 58 raw medicinal materials such as astragalus root, suberect spatholobus stem, Job stears, glabrous greenbrierrhizome, spreading hedyotis herb, barbed skullcap herb, motherwort herb and the like to manufacture oral agent and abrasive cleaner. The manufacturing method of the invention is as follows: 1. manufacturing by using the above raw material medicines into water-decocted liquid according to the conventional method; 2. manufacturing by using the water-decocted liquid which is manufactured in step 1 into oral liquid according to the conventional method; 3. drying, grinding and sieving the water-decocted liquid which is manufactured in step 1, and taking the throughs as powder; and 4. manufacturinginto powder tablets, granular formulation, medicinal granules or capsules by utilizing step 3 according to the conventional method. The powder and the abrasive cleaner can be manufactured by the following steps: 1. grinding the above raw material medicines; 2. sieving; and 3. taking the throughs, disinfecting and sterilizing to obtain the powder. The invention has high cure rate, low recurrence rate, can treat the primary and the secondary aspects at the same time, is safe and reliable, and can strengthen the autoimmunity. The invention mainly treats various types of posirasis, can treat neurodermatitis, comedo, acne and eczema concurrently, and has effects on lupus erythematosus, syphilis, lepra and skin cancer.

The present invention relates to a Chinese medicine composition, and especially a kind of Chinese medicine composition for treating lupus erythematosus, systemic scieroderm, dermatomyositis, panniculitis, behcets disease and connective tissue disease and its preparation process. The Chinese medicine composition is preferably prepared into dripping pill and soft capsule.

The invention discloses a traditional Chinese medicine for treating skin diseases and a preparation method thereof, which pertain to the technical field of Chinese medical pharmaceutical technology. The traditional Chinese medicine comprises 9 to 11 portions of kuh-seng, 9 to 11 portions of cyrtomium fortunei, 9 to 11 portions of honeysuckle, 9 to 11 portions of chrysanthemum, 4 to 6 portions of cicada skins, 4 to 6 portions of fresh licorice, 4 to 6 portions of fructus xanthii, 2 to 4 portions of amoorcorn tree bark and 2 to 4 portions of fructus kochiae, wherein the mixture ratio of the components is weight ratio. The preparation method of the traditional Chinese medicine is vinegar processing method. The traditional Chinese medicine has the functions of clearing heat and drying damp, clearing away heat and toxic materials, cooling blood, dispelling wind and removing heat, removing damp and relieving itching and has great treatment effect on the skin diseases such as whelk, eczema, skin itch, psoriasis, purpura, dermatophytosis, lupus sebaceus and the like, is the good medicine for treating skin diseases and can be used for treating the skin diseases.

The invention relates to a Chinese medicinal composition for relieving the hormone side effect of a western medicament when systemic lupus erythematosus (SLE) is treated. In the medicament, drying rehmannia root, mix-fried turtle shell, largetrifoliolious bugbane rhizome, spreading hedyotis herb, sweet wormwood herb, asiatic pennywort herb, red paeony root, fried coix seed, fingercitronsliced and raw liquoric root are combined, so that the Chinese medicinal composition can improve clinical symptoms of an SLE patient, contributes to raising the red blood cell count of the patient, lowers levels of triglyceride, cholesterol, erythrocyte sedimentation rate, urine protein and hematuresis of the SLE patient, reduces the using amount of the hormone, reduces the relapse rate, improves the overall curative effect, and can be combined with the western medicament to treat the systemic lupus erythematosus.

The invention provides a single preparation and compound preparation using halometasone as main constituent. The weight ratio of halometasone in pharmaceuticals is 0.0001-50%. The pharmaceuticals can be made into jellies, supensoid agent, liquor and pulvis, and the like, which are administrated in a percutaneous way. The preparation is suitable for dermatitis, eczema, vitligo, psoriasis, hives, rhinitis, lupus sebaceous, lichen planus and asthma, etc. The invention has the advantages of high healing rate, high safety and high promotional value.

An immunodepressive medicine is prepared from the monomer compound extracted from Tripterygium wilfordii, and has the forms of oral liquid, capsule, injection, or ointment. Its advantages are high curative effect to the rejection reaction of organ transplantation and immunopathy (such as lupus erythematosus) and no toxic by-effect.

The invention relates to a pharmaceutical composition prepared with micronized prasterone or sodium prasterone sulfate and a use thereof. The pharmaceutical composition comprises the following pharmaceutical ingredients: the micronized prasterone or the sodium prasterone sulfate, wherein the granulation size is 1 micron to 120 microns, preferably normal distribution of 1 micron to 50 microns, further preferably normal distribution of 10 microns. The content of the pharmaceutical ingredient is 10 mg-200 mg, preferably 25 mg-100 mg. The pharmaceutical ingredients can be prepared as the product in any pharmaceutically acceptable dosage form. The invention further provides the use of the pharmaceutical composition in preparing the drugs for treating and / or preventing sexual dysfunction, osteoporosis, lupus erythematosus, aesthetic dermatology, postpone senility and woman urogenital atrophy syndrome.

To solve the problem of an obvious side effect existing in the traditional Tripterygium Hypoglaucum Hutch root tablet, the invention provides a bi-layer extended release tablet which can reduce medicine peak plasma concentration. A Tripterygium Hypoglaucum Hutch root extract is any one extract of the whole Tripterygium Hypoglaucum Hutch root, Tripterygium Hypoglaucum Hutch root bark, or Tripterygium Hypoglaucum Hutch root core with the bark removed. The Tripterygium Hypoglaucum Hutch extract bi-layer extended release tablet has the characteristics of little untoward effect, and is convenient and safe to use. At the same time, a medicine-time curve is stable, the plasma concentration has small fluctuations, and the half life is prolonged. The Tripterygium Hypoglaucum Hutch root extract extended release bi-layer tablet using the root core with the bark removed has good therapeutic effects on asthma, lupus erythematosus, nephritis, and rheumatoid arthritis.

The invention discloses a traditional Chinese medicine composition for treating systemic lupus erythematosus, which comprises the following components by weight: 12-30 parts of buffalo horns, 9-15 parts of radix rehmanniae, 10-30 parts of hedyotis diffusa, 5-15 parts of radix rhapontici, 6-12 parts of cortex moutan, 6-12 parts of red peony roots, 5-10 parts of mix-fried muscardine silkworm, 3-10 parts of radix gentianae macrophyllae, 6-15 parts of caulis sinomenii, 9-15 parts of processed rhizoma polygonati, 6-12 parts of stir-fried atractylodes, 3-9 parts of tangerine peel. The present invention also discloses a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition of the invention has the efficacy of clearing heat and removing toxic substances, cooling blood and dissipating stasis, nourishing yin, promoting body resistance and eliminating pathogenic factors, can relieve the symptoms of fever (with a body temperature of below 38 DEG C), skin lesions, arthralgia, alopecia, Raynaud's phenomenon, photosensitivity, irregular menstruation, xerostomia, night sweat, and the like for lupus erythematosus patients, and can restore results of blood routine examination and main immunological indexes.

The invention provides application of three annular RNAs in a systemic lupus erythematosus biomarker. The three annular RNAs are respectively circ0082688, circ0082689 and circ0054189, and base sequences are respectively SEQ ID NO.1, SEQ ID NO.2 and SEQ ID NO.3. Compared with the whole blood of a healthy control, the three annular RNAs are significantly highly expressed in the plasma of a systemiclupus erythematosus patient, the whole blood circ0082688, circ0082689 and circ0054189 expression level of the systemic lupus erythematosus patient is higher than the healthy control. According to theapplication of three annular RNAs in the systemic lupus erythematosus biomarker, primers screening the three annular RNAs are prepared, a new idea is provided for studying the pathogenesis of the systemic lupus erythematosus, and a new target object is also provided for the early diagnosis of the three annular RNAs.

The invention belong to Chinese traditional medicine field, relates to the application of eucommia polysaccharide for preparing medicine preventing systematic Cazenave's lupus. The invention separates polysaccharide extract from eucommia, the average productivity is 2.2%, and the polysaccharide content is more than 68%. It is showed by whole animal model test that the protective effect for hyper reaction and kidney injury for mice by said polysaccharide is distinctive, and it is proven that polysaccharide can prevent Cazenave's lupus syndrome. The eucommia polysaccharide can also be used to produce medicine preventing and treating self-immune disease.

The invention belongs to the field of biotechnology, and discloses a function of a mini-chromosome maintenance complex component which plays an important role in immune dysfunction of systemic lupus erythematosus (SLE). The invention also discloses a method for detecting the level of the mini-chromosome maintenance complex component, and then for the auxiliary diagnosis of the systemic lupus erythematosus. The function of the mini-chromosome maintenance complex component in disease diagnosis and prevention of the systemic lupus erythematosus for the first time demonstrates that the mini-chromosome maintenance complex component family is closely related to the systemic lupus erythematosus, and the regulation and intervention of the mini-chromosome maintain protein level can improve the function of immune cells, and also provides a new drug target for the prevention and treatment of systemic lupus erythematosus.

The invention relates to a medicament for treating cheek erythema and a preparation method thereof. The medicament which can be absorbed well and stored for a long term, has stable curative effect and can directly act on the skin and mucosa is prepared by purifying various active ingredients of different medicaments and mixing the active ingredients further by reasonable preparation technology. The medicament is used for treating the cheek erythema in lupus erythematosus. A large number of animal experiments prove that the medicament has the advantages of no toxic or side effect and reliable curative effect.

The invention discloses a traditional Chinese medicine composition for treating systemic lupus erythematosus. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 15-30 parts of buffalo horn sheets, 20-30 parts of oldenlandia diffusa, 10-20 parts of radix rehmanniae, 10-15 parts of fructus forsythiae, 10-20 parts of radix paeoniae alba, 10-20 parts of cortex moutan, 10-15 parts of gentiana macrophylla, 15-20 parts of lalang grass rhizome and 10-15 parts of fried atractylodes macrocephala. The invention also discloses a preparation method and application of the traditional Chinese medicine composition for treating systemic lupus erythematosus. According to the formula, the traditional Chinese medicine composition has the favorable effects of inhibiting the generation of an autoantibody, forming an immune complex and inhibiting type-III allergic reaction, has favorable analgesic and anti-inflammatory effects, has a remarkable effect in clinical treatment and has a better effect as comparison with preliminarily-researched Langchuangqing granules, in addition, the formula is simple, the dosage is reduced, and caulis sinomenii serving as a poisonous traditional Chinese medicine in the formula is removed, so that the traditional Chinese medicine composition prepared according to the formula has more advantages from the views of safety and effectiveness as comparison with the Langchuangqing granules.

The invention belongs to the field of traditional Chinese medical care, and particularly relates to hydrogel for slow release of tripterygium hypoglaucum hutch extract and a paper diaper for the aged made of the same.Esterified chitosan serves as the water-soluble nano-porous frame carrier of the hydrogel, and the tripterygium hypoglaucum hutch extract serves as the solubilization slow release object.The paper diaper for the aged comprises a healthcare protection layer, an adsorption core coating layer, an adsorption core layer and a nano-hydrogel layer from outside to inside in sequence, wherein the nano-hydrogel layer is mainly formed by the hydrogel for slow release of the tripterygium hypoglaucum hutch extract.The hydrogel for slow release of the tripterygium hypoglaucum hutch extract can effectively reduce the peak plasma concentration of drugs and is a slow release preparation with a remarkable treatment effect.By the adoption of the paper diaper for the aged, the trouble of frequent clinical medication everyday and problems caused thereby are avoided, and medication efficiency and safety and patient compliance are improved.The paper diaper for the aged is mainly used for adjuvant treatment of rheumatoid arthritis, lupus erythematosus, chronic nephritis and autoimmune hemolytic anemia.

The invention discloses a medicament for treating burn, scald, frostbite, wound and symptoms of red, swell, pain, itch, pus and ulcer on various parts of the body surface. The medicament is mainly prepared from scorpio, scorpion, periostracum serpentis, eupolyphaga, rabiagar, saffron and hydrargyri oxydum rubrum according to a certain weight ratio. The medicament disclosed by the invention has the efficacies of relieving pain and itching (5-10 seconds), diminishing inflammation, sterilizing, healing wound and sore, removing the swelling and stasis (3-40 minutes) and resisting infection and tetanus, can be used for treating trauma and foreign invasion with symptom wound surfaces and has quick response and treatment rate and no scar left after the wound is cured. The medicament has the functions of inhibiting and killing staphylococcus aureus, streptococcus, anaerobic bacteria, fugus and gram-negative bacilli as well as eczema, urticaria, impetigo, decubitus, herpes zoster, lupus erythematosus, acne and pimple, various bite wound and stings by varipus animals and plants, and the like. The invention emphasizes on making up the defects of singleness, low effect, long period, and the like of the present relative medicaments and solves the problems of inadequate and unaffordable medical services for a part of patients in true sense.

The invention provides a Chinese traditional medicine for treating pruritus, which comprises the following traditional Chinese medicinal herbs (by weight portion), Sichuan coptis 4-20 parts, buthus martensi kirsch 3-18 parts, joss robe 5-18 parts, white atractylodes rhizome 8-25 parts, and is prepared into oral preparation and external soup by means of conventional methods.

The invention belong to Chinese traditional medicine field, relates to the application of bupleurum root polysaccharide for preparing medicine preventing systematic Cazenave's lupus. The invention separates polysaccharide extract from bupleurum root, the average productivity is 3.32%, and the polysaccharide content is more than 65%. It is showed by whole animal model test that the protective effect for hyper reaction and kidney injury for mice by said polysaccharide is distinctive, and it is proven that polysaccharide can prevent Cazenave's lupus syndrome. The bupleurum root polysaccharide can also be used to produce medicine preventing and treating self-immune disease.

The invention relates to a traditional Chinese medicine composition for treating cancer and a preparation method thereof. The traditional Chinese medicine composition is prepared from, by weight, 1-12 parts of peach kernels, 1-12 parts of radix angelica sinensis, 1-13 parts of common burreed rhizomes, 1-13 parts of rhizoma curcumae, 1-14 parts of milkvetch roots, 1-14 parts of spreading hedyotis herb, 1-14 parts of barbed skullcap herb, 1-13 parts of the root of common peony, 1-14 parts of kelp, 1-13 parts of manyleaf paris rhizomes, 1-13 parts of leeches, 1-14 parts of seaweed, 1-13 parts of gadflies, 1-11 parts of Chinese blister beetles, 1-13 parts of woodice, 1-14 parts of radix bupleuri, 1-14 parts of black nightshade, 1-14 parts of prunella spike, 1-13 parts of the root of red-rooted salvia and 1-12 parts of safflower. The traditional Chinese medicine composition can treat lung cancer, gastric cancer, carcinoma of the rectum, prostatic cancer, lymph cancer, metrocarcinoma, cervical cancer, esophagus cancer, kidney cancer, carcinoma of urinary bladder, ovarian cancer, pancreatic cancer, leukemia and lupus erythematosus, all of which are cured within one to two courses of treatment, and has a good treatment effect on various kinds of cancer, and cancer does not relapse after being cured.

The invention discloses a medicinal composition for treating dermatomyositis. The medicinal composition is prepared from the following main raw materials in part by weight: 100 to 200 parts of buffalo horn, 10 to 100 parts of tripterygium wilfordii, 100 to 200 parts of rehmannia root, 10 to 100 parts of rhubarb, 100 to 200 parts of sweet wormwood herb, 100 to 200 parts of red-rooted salvia root, 100 to 200 parts of suberect spatholobus stem, 100 to 200 parts of astragalus, 10 to 100 parts of epimedium herb and 10 to 100 parts of liquoric root. A preparation method for the medicinal composition comprises the following steps of: weighing the raw materials according to a formula, and uniformly mixing the raw materials by crush and water extraction and concentration or in a mode of combining the crush and the water extraction and concentration to obtain the medicinal composition. The medicinal composition can clear heat and cool blood, remove toxicity and dredge collaterals, tonify qi, strengthen the body resistance and nourish blood, and is used for fever, erythema, pain of joints and muscle, swell, laborious activity and the like caused by systemic lupus erythematosus, dermatomyositis and other rheumatism immunological diseases.

A Chinese medicine including interior-applied and exterior-applied medicines for whitening skin and treating pigmented spots, pigmentation, itching, skin rash, photosensitive dermatitis, etc is prepared from 4-5 Chinese-medicinal materials including ash bark, mulberry leaf, buffalo horn, etc.

The invention discloses an external detoxification and anti-inflammatory composition and relates to the technical field of traditional Chinese medicines. The composition solves the technical problem that the existing herpes zoster, herpes, erysipelas and lupus erythematosus are difficult miscellaneous diseases and cannot be treated by drugs. The composition comprises, by weight, 40 to 75 parts of mung bean powder, 12 to 40 parts by of poria cocos powder, 4 to 28 parts of rhizoma nardostachyos powder, 4 to 23 parts of rhizoma typhonii powder and 4 to 28 parts of houttuynia powder.

The invention provides an application of bryopsis plumose polysaccharide in an anticomplementary medicament. The bryopsis plumose polysaccharide has the complementary activity; the application of the bryopsis plumose polysaccharide refers to an application of the bryopsis plumose polysaccharide with the complementary activity in preparation of an anticomplementary medicament or / and an anticomplementary health-care product. According to the application provided by the invention, the condition that the bryopsis plumose polysaccharide has a significant inhibiting effect on complementary activities of a classical pathway and an alternative pathway is found out for the first time. The invention discloses the application of the bryopsis plumose polysaccharide in preparation of the anticomplementary medicament and health-care product. Excessive activation of a complement system can be inhibited, so that the bryopsis plumose polysaccharide has certain prevention and treatment effects on a plurality of diseases such as systemic lupus erythematosus, rheumatoid arthritis and acute respiratory distress syndrome caused by excessive activation of the complement system.

The invention provides a Chinese herbal preparation for treating posirasis, which adopts 58 raw medicinal materials such as astragalus root, suberect spatholobus stem, Job stears, glabrous greenbrier rhizome, spreading hedyotis herb, barbed skullcap herb, motherwort herb and the like to manufacture oral agent and abrasive cleaner. The manufacturing method of the invention is as follows: 1. manufacturing by using the above raw material medicines into water-decocted liquid according to the conventional method; 2. manufacturing by using the water-decocted liquid which is manufactured in step 1 into oral liquid according to the conventional method; 3. drying, grinding and sieving the water-decocted liquid which is manufactured in step 1, and taking the throughs as powder; and 4. manufacturing into powder tablets, granular formulation, medicinal granules or capsules by utilizing step 3 according to the conventional method. The powder and the abrasive cleaner can be manufactured by the following steps: 1. grinding the above raw material medicines; 2. sieving; and 3. taking the throughs, disinfecting and sterilizing to obtain the powder. The invention has high cure rate, low recurrence rate, can treat the primary and the secondary aspects at the same time, is safe and reliable, and can strengthen the autoimmunity. The invention mainly treats various types of posirasis, can treat neurodermatitis, comedo, acne and eczema concurrently, and has effects on lupus erythematosus, syphilis, lepra and skin cancer.

The present invention discloses one kind of orally taken Chinese medicine composition for treating lupus erythematosus, and belongs to the field of Chinese medicine technology. The Chinese medicine composition is prepared with 11 kinds of Chinese medicinal materials, including buffalo horn, clematis root, astragalus root, notoginseng, safflower, etc in certain weight proportion, and through filing buffalo horn into flakes, decocting the Chinese medicinal materials and other steps. It has obvious curative effect and no any toxic side effect.

A Chinese medicine including interior-applied and exterior-applied medicines for whitening skin and treating pigmented spots, pigmentation, itching, skin rash, photosensitive dermatitis, etc is prepared from 4-5 Chinese-medicinal materials including ash bark, mulberry leaf, buffalo horn, etc.

The invention belongs to the field of pharmacy, and specifically relates to an immunosuppressive drug and a preparation method thereof, which extracts a monomer compound norzeramydal from Tripterygium wilfordii as an active ingredient. The monomer compound norzeramydal of the present invention can be used as a drug raw material to make oral sustained-release preparations, soft capsules, injections, ointments and the like. The immunosuppressive drug of the present invention has few toxic side effects, wide sources, low production cost, cheap price, and convenient application. The drug of the present invention has obvious anti-rejection effect after organ transplantation, and can also be used to treat other clinical autoimmune diseases such as lupus erythematosus Wait.

The invention discloses a medicament for treating burn, scald, frostbite, wound and symptoms of red, swell, pain, itch, pus and ulcer on various parts of the body surface. The medicament is mainly prepared from scorpio, scorpion, periostracum serpentis, eupolyphaga, rabiagar, saffron and hydrargyri oxydum rubrum according to a certain weight ratio. The medicament disclosed by the invention has the efficacies of relieving pain and itching (5-10 seconds), diminishing inflammation, sterilizing, healing wound and sore, removing the swelling and stasis (3-40 minutes) and resisting infection and tetanus, can be used for treating trauma and foreign invasion with symptom wound surfaces and has quick response and treatment rate and no scar left after the wound is cured. The medicament has the functions of inhibiting and killing staphylococcus aureus, streptococcus, anaerobic bacteria, fugus and gram-negative bacilli as well as eczema, urticaria, impetigo, decubitus, herpes zoster, lupus erythematosus, acne and pimple, various bite wound and stings by varipus animals and plants, and the like. The invention emphasizes on making up the defects of singleness, low effect, long period, and the like of the present relative medicaments and solves the problems of inadequate and unaffordable medical services for a part of patients in true sense.

The invention provides a micro-ecological preparation eye drop. The micro-ecological preparation eye drop is prepared from a micro-ecological preparation and trace elements required to eyes in a scientific proportion. According to the eye drop, side effects of traditional Chinese medicines and western medicines on a human body can be changed, probiotics are used for killing eye germs and decomposing viruses, original probiotics of eyes cannot be killed, human body cells, tissues or organs cannot be hurt, injured cells can be repaired, human body immunity can be improved, trace elements required to eyes can be supplied, inflammation can be eliminated, and eye functions can be recovered. The eye drop has curative effects on keratitis, shortsightedness, glaucoma, cataract and other ocular diseases, is capable of treating diabetes mellitus, and is capable of treating influenza, oral ulcer, acute and chronic aryngitis, rhinitis, enteritis, gastritis, duodenal ulcer, diarrhea, constipation, ozostomia, dermatophytosis, hypertension, hyperlipidemia, lupus erythematosus, phthisis, epidemics, cancer and AIDS. The micro-ecological preparation and trace elements required to human bodies are combined scientifically so as to effectively delay human body senescence.

The invention belongs to the technical field of treatment of skin diseases and discloses traditional Chinese medicine composition for treating skin diseases. The traditional Chinese medicine composition is prepared from components in parts by weight as follows: 20-40 parts of realgar, 20-40 parts of rhizoma arisaematis, 10-20 parts of centipede, 10-20 parts of geckos, 20-40 parts of buffalo horns,20-40 parts of common ducksmeat herbs, 2-8 parts of white arsenic, 15-25 parts of dragon's blood, 20-40 parts of cortex dictamni, 15-25 parts of sodium sulfate, 15-25 parts of white alum and 10-20 parts of fel ursi. After the focus ulcer surface is disinfected, ointment prepared from the traditional Chinese medicine composition is smeared to the affected part, the medicine is changed once every day, so that the drug properties of the ointment are absorbed by skin to moisturize skin, eliminate dampness, expel toxins, soften hardness, eliminate swelling, remove slough and promote growth of tissue regeneration. The traditional Chinese medicine composition reaches the toxins through absorption by epidermis, toxins are expelled from the skin, and the skin recovers normal. Lupus erythematosus and leukoderma can be fundamentally treated within three months, ordinary obstinate sore, pressure sore and stubborn dermatitis can be fundamentally treated within half a month to one month, and no relapse is caused.