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Medicinal composition for treating dermatomyositis and preparation method thereof

A composition and technology of dermatomyositis, applied in the field of preparation of pharmaceutical preparations, can solve problems such as toxicity and adverse reactions, long-term application limitations, and achieve significant clinical curative effect and definite curative effect

Active Publication Date: 2012-09-19
HEBEI GOGIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the toxicity and adverse reactions of these drugs limit their long-term use

Method used

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  • Medicinal composition for treating dermatomyositis and preparation method thereof
  • Medicinal composition for treating dermatomyositis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] A pharmaceutical composition for treating dermatomyositis. The main medicinal raw materials of the pharmaceutical composition are: buffalo horn 120; Tripterygium wilfordii 60; Rehmannia glutinosa 120; Caulis Spatholobus 120; Astragalus 120; Epimedium 48; Licorice 40. Its preparation steps include:

[0039] A. Take each medicinal raw material according to the above formula, wherein the six herbs of buffalo horn, rhubarb, artemisia annua, salvia miltiorrhiza, astragalus, and licorice are pulverized into fine powder;

[0040]B. Tripterygium wilfordii, rehmannia glutinosa, Caulis Spatholobus, and Epimedium add 8 times the amount of water to decoct three times, each time for 1 hour, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.10g / ml~1.20 g / ml (50-60°C) clear paste;

[0041] C. Add the fine powder obtained in step A to the clear paste of step B, mix well, dry at 80°C, pulverize into fine powder, and pass through a 80-mesh sieve;

...

Embodiment 2

[0044] A pharmaceutical composition for treating dermatomyositis. The main medicinal raw materials of the pharmaceutical composition are: buffalo horn 114; tripterygium wilfordii 55; rehmannia 125; rhubarb 42; artemisia annua 124; Caulis Spatholobus 116; Astragalus 115; Epimedium 45; Licorice 41.

[0045] The preparation method is as follows: according to the above-mentioned formula, each medicinal raw material is weighed, crushed into fine powder, sieved, and 100 g of the obtained powder is mixed with 27 g to 33 g of water to make 1000 g of honeyed pills, and dried to obtain the finished product.

Embodiment 3

[0047] The formulation of the pharmaceutical composition of this embodiment is the same as that of Example 1.

[0048] Its preparation method is: according to the above formula, take each effective raw material, add 8 times the amount of water to decoct twice, the first time for 2 hours, the second time for 1.5 hours, combine the decoction, filter, concentrate into a thick paste, Add sucrose powder (the amount of sucrose powder is: to make 10 g of product granules per 15 g of raw medicinal materials), mix and granulate, and dry to obtain the finished product.

[0049] In addition, honey or other pharmaceutically acceptable excipients can be added to the dry paste, thick paste or powder mixture prepared in the above embodiments of the present invention to make pills or other clinically acceptable granules, dropping pills, tablets, Capsules, suspensions, oral liquid preparations, etc.

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Abstract

The invention discloses a medicinal composition for treating dermatomyositis. The medicinal composition is prepared from the following main raw materials in part by weight: 100 to 200 parts of buffalo horn, 10 to 100 parts of tripterygium wilfordii, 100 to 200 parts of rehmannia root, 10 to 100 parts of rhubarb, 100 to 200 parts of sweet wormwood herb, 100 to 200 parts of red-rooted salvia root, 100 to 200 parts of suberect spatholobus stem, 100 to 200 parts of astragalus, 10 to 100 parts of epimedium herb and 10 to 100 parts of liquoric root. A preparation method for the medicinal composition comprises the following steps of: weighing the raw materials according to a formula, and uniformly mixing the raw materials by crush and water extraction and concentration or in a mode of combining the crush and the water extraction and concentration to obtain the medicinal composition. The medicinal composition can clear heat and cool blood, remove toxicity and dredge collaterals, tonify qi, strengthen the body resistance and nourish blood, and is used for fever, erythema, pain of joints and muscle, swell, laborious activity and the like caused by systemic lupus erythematosus, dermatomyositis and other rheumatism immunological diseases.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to a traditional Chinese medicine preparation made from plant Chinese herbal medicines for clearing away heat and cooling blood, detoxifying and dredging collaterals, nourishing qi, nourishing blood and strengthening health; the invention also relates to a preparation method of the medicine preparation. Background technique [0002] Dermatomyositis (DM) is a non-suppurative disease of striated muscle. It is a chronic inflammation characterized by progressive symmetrical proximal muscle weakness and a certain degree of muscle atrophy and typical skin damage, and can accumulate multiple systems and organs. sexual autoimmune disease. The exact etiology of this disease is not very clear, it is currently considered to be an autoimmune disease caused by the joint action of genetic susceptibility and environmental factors. There is still no specific treatment, and it is an intractable d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61P21/00A61P17/00A61P37/02A61P19/04A61P29/00A61P19/02A61K35/32
Inventor 黄怀鹏王小军韩聚方陶君李静涵
Owner HEBEI GOGIN PHARMA
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