731 results about "Duodenal ulcer" patented technology

Chemical syntheses and medical uses of novel inhibitors of the gastric H+, K+-ATPase for the treatment and / or management of duodenal ulcers, heartburn, acid reflux, other conditions mediated by gastric acid secretion and / or psoriasis are described.

The invention provides a health-care flour composition and food and a preparing method thereof. According to the preparing method, hericium erinaceus and flour are used as main raw materials, swelling agents, sweetening agents, oil, salt and the like are added and mixed with water, and then rolling, forming, baking, oil injection and cooling are carried out to obtain various foods made of flour or pastries such as cookies, cakes and noodles. The health-care flour composition and food are even in texture, capable of being stored for a long time easily, good in mouthfeel and rich in nutrient, and market vacancy is filled. The health-care flour composition and food have definite effects in repairing gastric mucosal damage caused by chronic gastritis, or gastric ulcers or duodenal ulcers, relieving abdominal pains caused by chronic gastritis, or gastric ulcers or duodenal ulcers, inhibiting helicobacter pylori, and assisting the treatment of chronic gastritis, gastric ulcers and duodenal ulcers.

A surgical apparatus has a body portion that includes a shaft terminating in a distal head or tip for directing light radiation from the apparatus onto the lining of a body cavity for treating an ailment in a body cavity of a patient as for example a gastrointestinal ailment of a patient such as gastritis, gastric ulcer, duodenal ulcer, gastric cancer, gastric lymphoma, ulcerative colitis, or Crohn's disease as well as for treating diseases of the circulatory system, urogenital systems and other body cavities. During use, the shaft of the apparatus is inserted into a body cavity, e.g., stomach or colon, of the patient to place the distal tip of the shaft in the desired position. The body cavity of the patient is then irradiated with light radiation so as to kill or debilitate microorganisms lining the body cavity without serious destruction of the body tissue of the patient to thereby improve or alleviate one or more of the symptoms of the ailment. A probiotic comprising innocuous bacteria can be administered to the patient to reestablish the growth of normal microbial flora when treating the gastrointestinal tract.

The invention discloses a medicinal composition for treating peptic ulcer, which is a preparation prepared from the following Chinese herbal medicines in part by weight: 14 to 26 parts of coix seed, 14 to 26 parts of Chinese waxgourd semen, 10.5 to 19.5 parts of virgate wormwood herb, 10.5 to 19.5 parts of largehead atractylodes rhizome, 7 to 13 parts of perilla leaf, 7 to 13 parts of bitter apricot seed, 7 to 13 parts of white hyacinth bean, 7 to 13 parts of nutmeg, 7 to 13 parts of astragalus, 3.5 to 6.5 parts of ginseng and 3.5 to 6.5 parts of weeping forsythia. The medicinal composition exerts a synergistic effect after being subjected to reasonable compatibility, and can effectively treat gastric ulcer, duodenal ulcer and erosive gastritis, and a new medication choice is provided forclinically treating peptic ulcer.

The slimming diet fiber biscuit is produced with flour and diet fiber as main material and supplementary material including salt, seasoning, etc. The diet fiber will expand after absorbing water and this makes the eater produce satiety to reduce the ingestion; and it will reduce the time for food to stay in intestinal tract to consume fat inside body and result in slimming effect. In addition, ingesting diet fiber can reduce the re-absorption amount and alter food digesting speed and digestion secretion amount to prevent gall stone, duodenal ulcer, peptic colonitis and other diseases.

This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receotor 1; VR1; TRPV1 )antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, migraine, arthralgia, neuralgia, neuropathies, nerve injury, skin disorder, urinary bladder hypersensitiveness, irritable bowel syndrome, fecal urgency, a respiratory disorder, irritation of skin, eye or mucous membrane, stomach-duodenal ulcer, inflammatory diseases, ear disease, and heart disease.

The invention discloses a traditional Chinese medicinal formula for treating gastropathy. The formula comprises Radix Codonopsis, Radix Astragali, Radix Pseudostellariae, Mythic Fungus, white peony root, Chinese angelica, Rhizoma Atractylodis Macrocephalae, Chinese yam, haw, malt, medicated leaven, Atractylodes lancea, Panax Notoginseng, radix bupleuri, Rhizoma Cyperi, Rhizoma Corydalis, cuttlefish bone, Radix et Rhizoma Nardostachyos, Immature Bitter Orange, Poria cocos, Villous Amomum Fruit, dried orange peel, Radix Aucklandiae, chicken's gizzard membrane, cortex magnoliae officinalis and licorice according to the monarch, minister, assistant and guide of the traditional Chinese medicinal science. The monarch medicines comprise the Radix Codonopsis, the Radix Pseudostellariae, the Radix Astragali and the Mythic Fungus; the minister medicines comprise the white peony root, the Chinese angelica, the Rhizoma Atractylodis Macrocephalae, the Chinese yam, the haw, the malt, the medicated leaven, the Atractylodes lancea, the Panax Notoginseng, the radix bupleuri, the Rhizoma Cyperi, the Rhizoma Corydalis, the cuttlefish bone and the Radix et Rhizoma Nardostachyos; the assistant medicines comprise the Immature Bitter Orange, the Poria cocos, the Villous Amomum Fruit, the dried orange peel, the Radix Aucklandiae, the chicken's gizzard membrane and the cortex magnoliae officinalis; and the guide medicine is the licorice. The medicine of the formula has the efficacies of liver smoothing and depression resolving, center supplementing and qi boosting, qi moving and stomach harmonizing, and dampness eliminating and spleen invigorating, has special curative effects on chronic gastritis (comprising superficial gastritis, erosive gastritis and atrophic gastritis), gastric ulcer and duodenal ulcer, and has the advantages of short treatment course, fast effectiveness, and reaching of the effective rate of 98%.

The Chinese medicine composition for treating gastritis, gastric ulcer and duodenal ulcer is prepared with pinellia tuber, skullcap root, dry ginger, ginseng, corydalis tuber and other 14 kinds of Chinese medicinal materials in certain weight proportion. It is used mainly in treating chronic atrophic gastritis, gastric ulcer, duodenal ulcer, hyperchlorhydria and other gastrointestinal diseases. The Chinese medicine composition of the present invention has the advantages of scientific recipe, high curative effect, simple preparation process, etc.

Compositions and methods for treating, reducing, or preventing a disease or symptom such as gingivitis, periodontitis, gastritis, colitis, ileitis, Crohn's disease, chronic inflammatory intestinal disease, inflammatory bowel syndrome, chronic inflammatory bowel disease, celiac disease, ulcerative colitis, a gastric ulcer, a peptic ulcer, a buccal ulcer, a nasopharyngeal ulcer, an esophageal ulcer, a duodenal ulcer, a gastrointestinal ulcer, an autoimmune disorder, or pain. The method includes identifying a patient in need of treatment and administering a therapeutically effective amount of at least one cationic steroid antimicrobial (CSA), or a pharmaceutically acceptable salt thereof. Kits comprising such compositions and instructions on such methods are also contemplated herein.

Live strains of Lactococcus sp. HY 49, Lactobacillus casei HY 2782, and Bifidobacterium longum HY 8001 maintained in nutritious foods, such as yogurt, imbue them with prophylactic and / or therapeutic properties. Such foods are beneficial in the prevention and / or treatment of gastritis, duodenal and gastric ulcers caused by infection from Helicobacter pylori (also referred to as H. pylori). The properties of these bacteria are boosted by the addition of egg yolk containing antibodies specific to H. pylori antigen derived from "fractionated H. pylori".

The dispersed tablet of proton pump inhibitor is used for treating gastric ulcer, duodenal ulcer, stomal ulcer and other indications. It contains at least one kind of proton pump inhibitor and at least one kind of biologically acceptable buffering agent in the weight ratio of 1 to 10-200. The proton pump inhibitor is one selected from omeprazole, S-omeprazole, pantoprazole, lansoprazole, rabeprazole, leminoprazole, tenatoprazole and their salts. The biologically acceptable buffering agent is sodium bicarbonate, sodium carbonate, magnesium carbonate, etc or their mixture.

The invention discloses a new Chinese medicine composite for treating duodenal ulcer and a preparation method thereof. The Chinese medicine composite mainly comprises the following active pharmaceutical ingredients of stir-fried frankincense, stir-fried myrrh, semen coicis, lignum dalbergiae odoriferae, pericarpium citri reticulatae, fructus hordei germinatus, medicated leaven, radix trichosanthis, tuckahoe, rhizoma coptidis, baikal skullcap root, radix sophorae flavescentis, densefruit pittany root-bark, Chinese wolfberry root-bark, white flower patrinia herb, fructus amomi, lignum aquilariae resinatum, aspongopus, rhizoma corydalis, raw radix astragali, rhizoma dioscoreae, radix codonopsis and white peony root, and the like. The Chinese medicine composite can be prepared to be any common oral preparation according to the conventional Chinese medicine preparation method. The Chinese medicine composite can obviously improve epigastric pain, vague pain and complaint, hemorrhea, gastric perforation, obstruction and the like, which has definite clinical effect, obvious curative effect and fast desired effect. Due to the combination of the medicines both as food and medicine according to state-promulgated pharmacopoeia, the Chinese medicine composite of the invention has the advantages of low cost, basically no toxic side effect and the like.

The invention provides an r-lansoprazole for injection and a preparation method thereof. The medicament comprises active components of r-lansoprazole, or r-lansoprazole salt or r-lansoprazole water crystal as well as an excipient, a pH regulator and an antioxidizer. The preparation method comprises the following steps of: dissolving raw and auxiliary materials in water; adjusting the pH value; adding active carbon to decolor; filtering with a filter membrane; sub-packaging; freezing and drying to obtain the r-lansoprazole. The medicament is clinically used for treating gastric ulcer, duodenal ulcer, erosive gastro-esophageal reflux disease, helicobacter pylori, zollinger-ellison syndrome, and the like, can prevent the orally taken r-lansoprazole from being damaged in gastric acid and reach the aims of fast onset and improving the bioavailability.

The invention belongs to the field of pharmaceutical preparations, and particularly relates to novel rabeprazole sodium enterosoluble micro-particles with high stability in an acid medium, and a preparation method thereof. Each rabeprazole sodium enterosoluble micro-particle comprises a blank pill core (1), a medicine-carrying layer (2), an isolation coating layer (3) and an enteric coating layer (4) in sequence from inside to outside. A pH value regulator is used in the medicine-carrying layer, the isolation coating layer is added between the medicine-carrying layer and the enteric coating layer, and particularly, a retarding agent is added into an enteric coating layer combination, so that the acid tolerance of a medicament active ingredient namely rabeprazole sodium which is extremely unstable in acid is well improved. The rabeprazole sodium enterosoluble micro-particles and a preparation thereof can be used for treating diseases such as active duodenal ulcer, benign active gastric ulcer, rodent or ulcerative gastroesophageal reflux accompanied by clinical symptoms and the like.

The invention provides a traditional Chinese medicine capsule (Commodity Name: Weishuning Capsule) used for curing acute and chronic gastric diseases and esophageal enteric diseases, in particular to a traditional Chinese medicine capsule used for treating digestive system diseases; the traditional Chinese medicine capsule can prevent digestive tract cancerization through long-term oral application. The traditional Chinese medicine capsule essentially comprises the components of cuttlebone, concha arcae, ginseng, goldenthread root, common aucklandia root, lilac, semen amomi, amomum cardamomum, rhizoma corydalis, largehead atractylode, spicebush root, bergamot, cinnamon, semen raphani, green tangerine peel, ventriculi galli mucosa, magnolia officinalis, hyacinth bletilla, asarum, areca, agalloch, burreed tuber, zedoary, rhubarb root, calcined concha ostreae, immature orange fruit and liquorice. Coarse powder and a concentrated solution are mixed according to certain proportion, stirred, dried, smashed and sieved to prepare the traditional Chinese medicine capsule; the traditional Chinese medicine capsule has good curative effect for treating varied gastrointestinal diseases including acute and chronic gastritis, gastrointestinal hemorrhage, gastric acid, stomach-ache and duodenal ulcer, superficial, atrophic and vesicant gastritis, colonitis, etc. The traditional Chinese medicine capsule has simple prescription and preparation technique, low cost and is applicable to people in countries and mountainous areas where doctors and medicines are insufficient.

The invention belongs to the field of medicinal preparations and a novel medical technology and relates to an in situ gel preparation loaded with Kangfuxin and its preparation method and use. The in situ gel preparation loaded with Kangfuxin has temperature sensibility. The in situ gel preparation loaded with Kangfuxin is characterized in that Kangfuxin as a raw material and polymers are dissolved in a buffer solution or purified water according to a ratio. Because of polymer reverse-phase gel properties, the in situ gel preparation loaded with Kangfuxin is in a liquid state and can freely flow at a room temperature (of 20 DEG C) under storage conditions, and when the in situ gel preparation loaded with Kangfuxin is spread on a wound, under the action of a body temperature, the in situ gel preparation loaded with Kangfuxin forms fast semi-solid gel. The in situ gel preparation loaded with Kangfuxin is convenient for patient use, improves patient compliance, can effectively store drugs and can slowly release drugs so that drug action time is prolonged and drug efficacy is improved. Through oral administration, the in situ gel preparation loaded with Kangfuxin can be used for treating blood stasis, stomachache, gastrorrhagia, gastric ulcer and duodenal ulcer and assistantly treating Yin deficiency and pulmonary tuberculosis, and phthisis. Through external administration, the in situ gel preparation loaded with Kangfuxin can be used for treatment and anti-adhesion of metal-inflicted wounds, trauma wounds, ulcer wounds, fistula wounds, burn wounds, scald wounds, bedsore wounds and surgical wounds.

The invention discloses a rhodiola rosea compound composition for treating peptic ulcer. The rhodiola rosea compound composition is a preparation prepared from the following active pharmaceutical ingredients in parts by weight: 4.2-7.2 parts of rhodiola rosea, 14-26 parts of poria cocos, 10.5-19.5 parts of dandelion, 10.5-19.5 parts of capillary artemisia, 10.5-19.5 parts of white atractylodes rhizome, 7-13 parts of pogostemon cablin, 7-13 parts of raw malt, and 3.5-6.5 parts of fructus amomi rotundus. The compound composition disclosed by the invention is exact in compatibility of medicines, quite less in medical ingredients, not only capable of ensuring medicine efficacy and reducing side effects, but also capable of effectively treating gastric ulcer, duodenal ulcer, and erosive gastritis, and provides a new administration choice for the clinical treatment of the peptic ulcer.

The invention discloses a pharmaceutical preparation used for treating erosive reflux oesophagitis, a gastroesophageal reflux disease, maintaining a long-term therapy to prevent the recurrence of oesophagitis for a cured patient, controlling the symptoms of gastroesophageal reflux diseases, eradicating helicobacter pylori jointly medicated with an appropriate antimicrobial therapy, healing duodenal ulcer related to helicobacter pylori infections and preventing the recurrence of peptic ulcer related to helicobacter pylori, and particularly relates to a prepared sustained-release oral formulation adopting esomeprazole magnesium as the ingredient. The pharmaceutical preparation aims to supplement the deficiency of the prior art and provide a sustained-release esomeprazole magnesium dropping pill. The sustained-release esomeprazole magnesium dropping pill overcomes the defects in the prior art effectively, guarantees no occurrence of an obvious quality change for the drug during the effective storage period and has the advantages of controllable release time, full release and high bioavailability simultaneously.

A medicine Leibeilazuona for injection contains Leibeilazuona, excipient, pH regulator and antioxidizing agent. It can be used for treating stomach ulcer, duodenal ulcer, erosive gastroesophageal reverse flor disease, pyloric halicobacterium, and zollinger-ellison syndrome. Its advantages are high biological utilization rate and quickly taking its effect.

Methods are provided directed to adminstering a therapeutically effective amount of a prostaglandin EP4 agonist component to a mammal afflicted with or prone to affliction with a disease or condition selected from an esophageal ulcer, alcohol gastrophathy, a duodenal ulcer, non-steroidal anti-inflammatory drug-induced gastropathy, non-steroidal anti-inflammatory drug-induced enteropathy and intestinal ischemia. Such administration results in treating or preventing the disease or condition.

The present invention relates to one kind of chewing tablet of proton pump inhibitor for treating gastric ulcer, duodenal ulcer, stomal ulcer and other indications. The chewing tablet contains proton pump inhibitor in 1-5 wt%, carbonate in 35-60 wt% and hydroxide in 35-60 wt%. The proton pump inhibitor is one selected from omeprazole, S-omeprazole, pantoprazole, lansoprazole, rabeprazole, leminoprazole, tenatoprazole and their salts. The biologically acceptable buffering agent is selected from sodium bicarbonate, sodium carbonate, magnesium carbonate, calcium carbonate and their mixture, preferably sodium bicarbonate. The hydroxide is selected from magnesium hydroxide, calcium hydroxide, aluminum hydroxide, sodium hydroxide and their mixture, preferably magnesium hydroxide.

The invention provides a solanum dulcamara total saponins extract containing 10-90% of solanum dulcamara total saponins by weight, which is a total steroidal saponins made from traditional Chinese medicine solanum dulcamara by process of extracting, separating and refining. Animal tests shows that: the exact has substantial effects of anti-inflammatory, anti-tumor, helicobacter pylori inhibition, gastric mucosa protection and keratinocyte proliferation inhibition, can be used in the preparation of medicaments for treating gastritis, stomach and duodenal ulcer stomach cancer and psoriasis.

The invention relates to a dietetic therapy meal auxiliary or meal replacement product for gastric ulcer and duodenal ulcer. The main components and a preparation method are as below: first conducting superfine grinding on chicken's gizzard membrane, cape jasmine, a honeysuckle decoction, a kiwi fruit powder, pine pollen, a fingered citron powder, lily, processed licorice, clove and litchi into a powder, and adding a coix seed powder, a Poria powder, a wheat germ powder, a Chinese yam powder and a walnut powder; or decocting the materials with water, filtering the decoction and spraying a filtrate into the coix seed powder, the Poria powder, the wheat germ powder, the Chinese yam powder and the walnut powder; conducting high temperature slaking on the mixture; adding xylo oligosaccharide, a Lactobacillus acidophilus powder, a bifidobacterium powder, a natto powder, a yeast powder, an L-arabinose powder and a spirulina powder; mixing uniformly; and conducting subpackaging. The invention employs reasonable compatibility of materials which are used as both food and medicine and utilizes the principle of balance constitution in traditional Chinese medicine, so that the human body can restore balance and achieve the stable state of health through diet. The product reduces incidence of diseases related to gastric ulcer and duodenal ulcer physique and has the advanategs of safety, effectiveness, little toxic or side effect, common food as the main raw materials, low price and easiness for people to accept.

A Chinese medicine for treating gastritis, acute or chronic gastritis, duodenal bulbar inflammation, gastric ulcer, duodenal ulcer, etc is prepared from 16 Chinese-medicinal materials including dandelion herb, lily bulb, white peony root, tangerine peel, etc. Its preparing process is also disclosed.

The present invention discloses application of dihydromyricetin in preparation of medicine for curing the diseases of stomatocace, gastric ulcer, duodenal ulcer, acute or chronic pharyngitis, pelvic inflammation and / or annexitis, chronic gastritis and / or enteritis. It can be mixed with pharmaceutically acceptable carrier, and the prepared medicine can contain dihydromyricetin only, also can be composition containing dihydromyricetin, and said prepared medicine can be tablet, capsule, granula preparation or injection preparation, and every tablet or every capsule or every bag of granules or every injection contains 50-1000 mg of dihydromyricetin. Said invention also relates to a method for preparing dihydromyricetin from ampelopsis grossedentata by adopting low-temperature treatment recrystallization process.

The present invention is related to a hyaluronic acid formulation including a mixture of hyaluronic acids having different weight-average molecular weight and different rheological, tissue scaffold, insulation and degradation properties in aqueous solution. The resulting formulation demonstrated an optimal balance between adhesion, tissue scaffold, insulation and treating time on the treatment and prevention of IBD (inflammatory bowel disease) such as ulcerative colitis and Crohn's disease. Thus, the formulation of the present invention exhibits a quick and lasting effect on the treatment and prevention of duodenal or peptic ulcer and bleeding which is very good thing indeed.

A liposome of lansoprazole is prepared from lansoprazole, phosphatide, cholesterol and the supporting agent chosen from sorbitol, mannitol, cane sugar, sodium chloride, water-soluble starch, etc. It is used for treating gastric ulcer, duodenal ulcer, reflux esophagitis, etc. Its preparing process is also disclosed.

The present invention relates to a pure Chinese medicine preparation. Jianwei Kangning Jiaonang capsule for curing the diseases of chronic gastritis, atrophic gastritis, gastro-duodenal ulcer, bile-regurgitational gastritis, functional dyspepsia, peptic ulcer, chronic hepatitis and chronic cholecystitis with obvious therapeutic effect and high cure rate. Said medicine is made up by using 21 Chinese medicinal materials of white peony root, pinellia tuber, poria, unceria stem and thorn, alpinia fruit, fennel fruit and others.

The invention discloses a Chinese medicinal preparation for treating duodenal ulcer, which comprises the following Chinese herbal medicines in part by weight: 10 to 20 parts of astragalus, 10 to 20 parts of peach seed, 10 to 20 parts of bletilla, 10 to 20 parts of nutgrass galingale rhizome, 10 to 20 parts of white paeony root, 10 to 20 parts of largehead atractylodes rhizome, 10 to 20 parts of Indian buead, 10 to 20 parts of honey-fired liquoric root, 10 to 20 parts of emblic leafflower fruit, 10 to 20 parts of Chinese gall, 10 to 20 parts of combined spicebush root, 10 to 20 parts of tangerine peel, 10 to 20 parts of chicken's gizzard-membrane, 10 to 20 parts of notoginseng root, 10 to 20 parts of bupleurum, 10 to 20 parts of sanguisorba root, 10 to 20 parts of ginger, 10 to 20 parts of rosewood heart wood, 10 to 20 parts of root of red-rooted salvia, 10 to 20 parts of cuttlefish bone and 10 to 20 parts of cinnamomvine. The Chinese medicinal preparation has the effects of calming liver and regulating flow of qi, tonifying spleen, lung and kidney, tonifying middle-Jiao and qi and stopping bleeding and preventing or arresting vomiting, is mainly used for treating discomfort in spleen and stomach and weakness of the spleen and the stomach, and fulfills the aims of stopping diarrhea and diminishing inflammation, relieving spasm and pain, improving local blood circulation and metabolism, enhancing the immunologic function of intestinal tracts and promoting ulcer healing. The Chinese medicinal preparation has a simple preparation process, small toxic or side effects and low cost, and is convenient to administrate and easy to prepare.