The invention relates to a therapeutic medicine for cerebral embolism sequela, in particular, a therapeutic medicine for treating cerebral embolism sequela and a preparation method thereof which solve problems of poor cure effect, slow efficiency and the like existed in the prior art. Calculated by weight parts, the medicine is a medicament made from raw materials as follows: 70-100 parts of lumbricus, 30-50 parts of leech, 80-100 parts of ligusticum wallichii, 50-80 parts of Chinese angelica, 50-80 parts of uncaria rhynchophylla, 50-80 parts of peach kernel, 30-50 parts of red flower, 50-100 parts of gastrodia elata, 40-80 parts of caulis spatholobi, and 30-50 parts of radix salvia miltiorrhiza. The preparation method comprises the steps of: firstly, drying the raw materials, crushing to form fine powder of 100-200 meshes and sieving; then after mixing according said proportion, sterilizing and mixing uniformly to make into the medicament in a plurality of dosage forms, such as water-bindered pills, tablets, honey boluses or capsules. The medicine for treating cerebral embolism sequela disclosed by the invention is composed of natural animals and plants, so the medicine has a mild medicine property as well as no toxic side effect and adverse effect, is suitable for patients who are at different ages, suffer from stroke sequela and have different physic conditions to take for a long term in a stage of recovery.