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Pharmaceutical composition for treating cerebrovascular and cardiovascular diseases as well as preparation method and application

A composition and cardiovascular technology, applied in cardiovascular system diseases, drug combinations, blood diseases, etc., can solve the problems of lack of Chinese patent medicines and Western medicines, uncommon Chinese patent medicines, lack of effective varieties of Western medicines, etc., and achieve good curative effect

Inactive Publication Date: 2012-06-27
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The ingredients of these aromatic medicines are very depleting of the body's qi, blood and body fluids, and taking them for a long time is not good for the condition
At the same time, cerebrovascular and cardiovascular diseases need to continue to take effective treatment after first aid, and after the "emergency", follow-up treatment must be followed up as soon as possible, which is the most important and permanent treatment. Clinically, It's just that Western medicine lacks effective varieties in this area, and related Chinese patent medicines are not common, especially Chinese patent medicines and Western medicines that treat cerebrovascular and cardiovascular diseases at the same time are seriously lacking

Method used

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  • Pharmaceutical composition for treating cerebrovascular and cardiovascular diseases as well as preparation method and application
  • Pharmaceutical composition for treating cerebrovascular and cardiovascular diseases as well as preparation method and application

Examples

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Effect test

Embodiment 1

[0027] The preparation of embodiment 1 pharmaceutical composition of the present invention

[0028] Get 10g of Panax notoginseng total saponins, 10g of Chuanxiong total alkaloids, and 15g of Achyranthes bidentata total saponins, mix well, add microcrystalline cellulose, and pack into capsules to obtain the pharmaceutical composition capsule of the present invention.

[0029] For the preparation method and quality standard of Panax notoginseng saponins, refer to the item "Notoginseng total saponins" in Part I of "Chinese Pharmacopoeia" 2010 edition.

[0030] The preparation method of total alkaloids of Ligusticum chuanxiong can be carried out with reference to the existing preparation method, such as patent number: 200510020868.9, the total alkaloids of Ligusticum chuanxiong can not be less than 50% W / W calculated as ligustrazine hydrochloride. In the present invention, the following preparation method is adopted: take the coarse powder of Rhizoma Chuanxiong medicinal material,...

Embodiment 2

[0032] The preparation of embodiment 2 pharmaceutical compositions of the present invention

[0033]Take 7g of Panax notoginseng saponins, 13g of Chuanxiong total alkaloids, and 19.5g of Achyranthes bidentata total saponins, add appropriate amount of dextrin and soluble starch, mix well, and prepare granules.

Embodiment 3

[0034] The preparation of embodiment 3 pharmaceutical composition of the present invention

[0035] Take 13g of total saponins of Panax notoginseng, 7g of total alkaloids of Chuanxiong, 10.5g of total saponins of Achyranthes bidentata, add appropriate amount of compressible starch, mix well, granulate, add appropriate amount of magnesium stearate, and press into tablets.

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Abstract

The invention discloses a pharmaceutical composition for treating cerebrovascular and cardiovascular diseases as well as a preparation method and application. The pharmaceutical composition has antithrombotic and anti-stasis effects, and can be used for treating cerebral ischemia, cerebral thrombosis and cerebral embolism and other cerebrovascular diseases, hypertension and coronary heart disease, hyperlipidemia, atherosclerosis, myocardial ischemia, arrhythmia, heart failure, angina and myocardial infarction and other cardiovascular diseases, especially for further treating patients with cerebrovascular and cardiovascular diseases after first aid, with relatively good treating effect; therefore, a new choice is provided for clinical medicinal application.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating cerebrovascular and cardiovascular diseases, a preparation method and application thereof. Background technique [0002] Cerebrovascular and cardiovascular diseases have become the number one killer of human health, and their morbidity and mortality have already surpassed tumor diseases to rank first. Most patients need to take medicine for life. Cerebrovascular disease is a group of diseases that cause brain tissue damage due to brain blood supply disorders. It mainly affects middle-aged and elderly patients. Most patients present with hemiplegia and speech impairment. Most of these diseases are caused by vascular wall lesions atherosclerosis, hyperlipidemia, diabetes, hypertension, thrombocytosis, coronary heart disease, and poisoning. Common cerebrovascular diseases include transient ischemic attack, cerebral thrombosis, cerebral infarction, and stroke. In the International Classif...

Claims

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Application Information

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IPC IPC(8): A61K36/258A61P7/02A61P9/04A61P9/06A61P9/10
Inventor 李戎杨明
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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