The invention discloses a soothing repair serum containing a bifida ferment lysate. The soothing repair serum is prepared from, by weight, 1-10 parts of polyhydric alcohol, 1-10 parts of a moisturizing agent, 0.5-10 parts of a skin moisturizing agent, 0.5-5 parts of an emulsifying agent, 0.1-2 parts of a thickening agent, 0.1-2 parts of a pH adjusting agent, 0.1-5 parts of an anti-allergy soothingagent, 0.1-10 parts of a skin conditioning agent, 0.1-1 part of a preservative, 0.01-0.05 pat of essence and the balance deionized water, wherein the sum of the weight parts of all the components is100. The soothing repair serum can obviously reduce wrinkles, reduce the content of pigment, improve the glossiness of skin, brighten the skin color, improve the skin elasticity, repair the skin barrier and reduce moisture loss; the soothing repair serum is free of irritation to the skin, has the functions of preventing skin aging and perpetually moisturizing the skin and makes the skin in a healthy natural bright white status.