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737 results about "Blood capillary" patented technology

Blood capillary. n. One of the minute blood vessels that connect arterioles and venules and are a part of an intricate network throughout the body for the interchange of oxygen, carbon dioxide, and other substances between blood and tissue cells.

Specimen collecting, processing and analytical assembly

ActiveUS20050232813A1Prevent the biological marker from degradingEasy to storeAnalysis using chemical indicatorsSurgeryPreservativeBlood capillary
A specimen collecting, processing and analytical assembly, designed for testing small volumes of body fluids, substances and secretions, said assembly comprising a one piece barrel assembly with a volumetrically graduated capillary tube having an open end, and optionally coated internally with an anticoagulant, a stabilizer or a preservative. The barrel assembly includes a filter membrane fitted above the capillary end at the junction of the barrel assembly and the capillary tube, a support means at the barrel's second open end, and an analytical testing means disposed there between. The invention also provides a sealed vial containing an analytical testing reagent, the vial being substantially airtight and sealed with a pierceable material, a first tip cap for closing the open end of the capillary tube, a second cap to close sealably the second open end of the barrel container and a lancet to induce capillary skin punctures.
Owner:SAVVIPHARM INC

Method and apparatus for analyte measurement test time

A disposable biosensor test strip is provided that includes a plurality of penetrating members. Each penetrating member is associated with a capillary chamber that has a depth suitable for capillary flow of blood and holds a volume of less than about 1.0 μl of the blood sample. A working electrode and a counter or reference electrode are disposed within the capillary chamber. A reagent is proximal to or in contact with at least the working electrode. The reagent includes an enzyme and a mediator. The reagent reacts with glucose to produce an electroactive reaction product. A blood sample, containing glucose, is applied into the capillary chamber. The capillary chamber directs capillary flow of the blood sample into contact with the reagent to cause the blood sample to at least partially solubilize or hydrate the reagent. The blood sample is detected in the capillary chamber. The electroactive reaction product is electro-oxidized or electro-reduced at the working electrode. Within 10 seconds after detecting, a determination is made of glucose concentration and a readout of the measurement is provided. The glucose determination is made by correlating the electro-oxidized or electro-reduced electroactive reaction product to the concentration of glucose in the blood sample.
Owner:SANOFI AVENTIS DEUT GMBH

Dispensing device

An inhaler for enabling inhaled administration, has a housing having an outlet duct defining a passageway through which air can be drawn by inhalation on the part of a user. The housing contains a capillary nozzle; a container for containing a quantity of liquid to be supplied to the capillary nozzle; and an electric field controller for applying a voltage to the liquid prior to issue from the container via the capillary nozzle to expose the liquid to an electric field to cause comminution of the liquid emerging from the capillary nozzle to product a spray of electrically charged droplets such that upon inhalation by the user, electrically charged droplets for the deposition in the user's airways.
Owner:BATTELLE MEMORIAL INST

NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery

The invention describes novel formulations of nonsteroidal anti-inflammatory drugs (NSAIDs) based on complex aggregates with at least three amphipatic components suspended in a suitable, e.g. pharmaceutically acceptable, polar liquid medium. A suitably ionised NSAID is one of the two, amongst said three, components that tends to destabilise lipid membranes, the other system component with such activity being typically a surfactant. In contrast, the remaining amongst said at least three amphipatic components typically forms a stable lipid membrane on it's own. An essential characteristics of the resulting, relatively large, aggregates is an improved ability to penetrate pores, in a semi-permeable barrier, at least 30%, and often much smaller than the average diameter of the complex aggregate. This enables said aggregates to mediate NSAID transport through semi-permeable barriers including mammalian skin. As a result of the skin penetration by NSAID loaded large aggregates, the drug delivered transcutaneously with such carriers gets deeper into the tissue than the corresponding NSAID from a solution on the skin surface. This is believed to be due to the special ability of suitable large carriers to bypass the local sink of blood capillaries at the epidermal-dermal junction in the skin. The carrier-mediated delivery of locally applied NSAIDs thus allows therapy of deep tissues under the drug administration site, which is medically highly desirable.
Owner:IDEA AG

Production process of high-quality ecological antibacterial health-care sock

The invention discloses a production process of a high-quality ecological antibacterial health-care sock. The production process of the high-quality ecological antibacterial health-care sock comprises the following steps of yarn manufacturing, sock weaving, seam allowance processing, reinforcing, setting, pre-drying, water bathing, drying and package detection. The production process of the high-quality ecological antibacterial health-care sock adopts the method that natural cotton fibers, aloe fibers and modal fibers are interlaced and makes full use of the good antibacterial effect of the aloe fibers, and the bottom of the sock adopts a flat structure, so that the fabric can meet the requirements for high air permeability and comfort. The aloe fibers are used for replacing traditional common viscose, and aloe isocitric acid calcium and other matter have the functions of improving the constitution, strengthening the heart, promoting blood circulation, softening hardened arteries, lowering the cholesterol content and expanding the blood capillaries, and have a certain inhibition effect on escherichia coli and staphylococcus aureus. Compared with the prior art, the high-quality ecological antibacterial health-care sock has good health-care performance and antibacterial performance.
Owner:浙江丰悦针纺有限公司

Controlled release endoprosthetic device

InactiveUS20050192664A1Overcome problemsVascular smooth cell proliferation caused by stents can be reducedOrganic active ingredientsStentsBULK ACTIVE INGREDIENTPerfusion
The invention relates to improved drug-delivery endoprosthetic device for insertion at a vascular site via catheter placement at the site, comprising: (a) a structural member into the upper and / or lower surface of which one or more micro-deepenings are engraved and / or on which a polymer member is carried, for co-expansion with the polymer member from a contracted state to an expanded state when the device is exposed to said stimulus, (b) optionally a polymer member capable of expanding from a contracted to a stable, expanded state when the polymer member is exposed to a selected stimulus, wherein the device can be delivered from a catheter, with the structural and the optional polymer members in their contracted states, and is adapted to be held in a vessel at the vascular target site by radial pressure against the wall of the vessel, with the structural and the optional polymer members in their expanded states; and wherein the micro-deepenings of said structural member and / or said polymer member comprise a pharmaceutical composition containing one or more active ingredients selected from the group consisting of agents to inhibit or at least reduce excessive proliferation of vessel wall cells, agents to enhance the downstream perfusion of tissue, agents to promote and / or to enhance the neo-formation of capillaries, agents designed to modulate the amount or activity of coagulation factors, agents to reduce the amount of Thrombin- and / or Fibrin-formation, embedded therein for release from the member, with such in its expanded state.
Owner:BOEHRINGER INGELHEIM PHARM KG

Fluidic capillary chip for regulating drug flow rates of infusion pumps

An erosion-resistant capillary chip for use with in an infusion pump that is made from a silicon substrate having a first surface that includes a micro groove etched therein and a glass plate laminated to the first surface. The glass plate covers the micro groove so that a micro fluid conduit is created. The glass plate includes an inlet bore that connects with the micro fluid conduit and the silicon substrate includes an outlet bore that connects with the micro fluid conduit so that a drug solution entering the inlet bore from the infusion pump may pass through the micro fluid conduit at a restricted flow rate to the outlet bore and thereafter to a target site of a patient. The micro groove includes a passivation layer made from silicon nitride or silicon carbide that protects the micro groove against erosion from passing fluids having high basic or high acidic pH levels. A method for making the capillary chip is disclosed, as well as an infusion pump incorporating the improved capillary chip.
Owner:CODMAN NEURO SCI

Transmyocardial revascularization system and method of use

InactiveUS20050159726A1Increase perfusionMinimizing pain sensationStentsHeart valvesActive agentCardiac cycle
A transmyocardial revascularization system including a plurality of inserts formed of a material to elicit a healing response in tissue of the myocardium and deployment instruments and associated components for deploying the inserts into the wall of the myocardium. The inserts are arranged to be disposed within respective lumens or channels in the wall of the myocardium. The inserts can take various forms, e.g., be solid members, tubular members, or porous members, and may be resorbable, partially resorbable or non-resorbable. In some embodiments the inserts are arranged to be left in place within the channels in the wall of the myocardium to result in plural lumens which enable blood to flow therethrough and into contiguous capillaries. The deployment instruments are arranged to pierce the tissue of the myocardium from either the endocardium or the epicardium to insert the inserts into the myocardium, depending on the particular deployment instrument used. The deployment instruments may make use of a stabilizing device to stabilize them during the procedure of inserting the inserts into the myocardium. A controller may also be provided as part of the system to coordinate the operation of the deployment instrument with the cardiac cycle. The formation of the lumens can be achieved either by the inserts or by some other means, such as a piercing tip or an energy applicator forming a portion of the instrument. The inserts may include one or more of pharmaceuticals, biologically active agents, radiopaque materials, etc.
Owner:KENSEY NASH CORP
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