110 results about "Vascular dilation" patented technology

The invention provides methods for inducing or increasing the vasodilation of a vessel. The invention further provides methods for inducing or increasing the flow of fluid through a vessel. An electrical impulse is applied to the vessel in order to induce or increase vessel vasodilation or to induce or increase the flow of fluid through the vessel. In a particular embodiment, a novel double-balloon catheter system incorporating electroporation technology has been designed and is used to apply the electrical impulse endoluminally.

The invention provides methods for inducing or increasing the vasodilation of a vessel. The invention further provides methods for inducing or increasing the flow of fluid through a vessel. An electrical impulse is applied to the vessel in order to induce or increase vessel vasodilation or to induce or increase the flow of fluid through the vessel. In a particular embodiment, a novel double-balloon catheter system incorporating electroporation technology has been designed and is used to apply the electrical impulse endoluminally.

Exemplary embodiments comprise AV fistulas and other anastomotic devices for creating new or reinforcing existing side-branch vessels, and / or bridging neighboring vessels together. An exemplary embodiment may comprise a sidewall port, such as a flanged sidewall port, and / or flow frame design, such as a partially bare, flexible stent or a whisk, for purposes of creating a transmural flow. Another exemplary embodiment may comprise a compliant vessel support to aid in the transition from device to vessel and / or vessel to device, and to promote vessel dilation.

Methods and apparatus for treating hypertension and other vessel dilation conditions provide for delivering acoustic energy to a vascular nerve to remodel the tissue and nerves surrounding the vessel. In the case of treating hypertension, a catheter carrying an ultrasonic or other transducer is introduced to the renal vessel, and acoustic energy is delivered to the tissue containing nerves to remodel the tissue and remodulate the nerves.

A kit for performing angioplasty or stenting in a blood vessel, composed of at least two components. One of the components includes a first catheter providing a blood bypass flow path and carrying a blocking balloon and a blood vessel dilation device. Another one of the components includes a second catheter having an imperforate wall enclosing an axial lumen and having an open distal end, a hollow tube surrounding, and movable longitudinally with respect to, the second catheter, and a second blocking balloon carried by the hollow tube.

A method for accelerating subcutaneous absorption of a fluid or drug into the systemic circulation of a specific targeted tissue. A first drug operative to produce local capillary vasodilatation and / or increase the rate of bulk flow of solution through the interstitial space is mixed with a fluid. The fluid may contain a crystalloid solution or a dilute solution of a pharmacologic drug required for a routine or emergency therapeutic treatment for a patient. The first drug is substantially non-toxic to the patient. The fluid mixed with the first drug is then delivered subcutaneously or into deeper tissues of the patient, by use of a hyperdermic needle or infiltration cannula. As the capillaries are dilated, the fluid is efficiently absorbed and circulated systemically.

The specification discloses purine nucleotide analogues which modulate cardiac muscle contractility and possess vasodilator activity. In addition, related methods of administration and the identity of receptors that bind these compounds are disclosed.

The invention provides a wool fibre fabric sweat shirt (pants) with functions of powerful antibiosis, cancer prevention and life prolonging by utilizing nano silver, selenium and germanium, belonging to the technical field of healthy wool textile fibre fabrics clothes production. In the real life of people, various germs, viruses and fungi are contacted unavoidably, in particular, various bird flu and HIV discovered currently seriously threaten the health of human beings. Nano silver can kill 650 types of pathogens; far-infrared rays are almost absorbed by the skin of human body completely to lead the surface temperature of the skin to rise; heat energy impels the blood vessel to expand, improves blood circulation and microcirculation; the electromagnetic wave is colorless, tasteless and formless, can easily cause pollution to human body and is a potential killer. The anions in the air are vitamins and longevity elements in the air and are beneficial to human body; selenium and germanium are important elements to prevent and resist cancer; and the mixture of bee series can comprehensively supplement a plurality of nutrient active components required by human body. After nano treatment, the efficacy of anti-aging traditional Chinese medicine can be improved to 100 times.

Cold storage solutions for the preservation of organs and biological tissues prior to implantation, including a prostaglandin having vasodilatory, membrane stabilizing, platelet aggregation prevention upon reperfusion, and complement activation inhibitory properties, a nitric oxide donor, and a glutathione-forming agent.

Devices and methods are provided for forming a vascular graft by axially distending a blood vessel to induce growth. In one embodiment, a device for distending a blood vessel of a human or animal is provided which comprises a stretching mechanism attachable directly to a blood vessel at at least two attachment positions thereon, and a means for operating the stretching mechanism to cause the blood vessel portion between said at least two attachment positions to be stretched axially. The distended portion can then be excised and used as a graft.

A stent (1) comprising a hoselike body obtained by braiding a multiplicity of thin wires (2) of superelastic metal into plaited form. In the longitudinal intermediate portion of the hoselike body, mutually neighboring individual thins wires (2) of superelastic metal are in contact with each other or close to each other with a minute interspace and are formed into a thin wire densely braided hose portion (3) with a length needed to block any opening of blood vessel dilation. At both side portions thereof, mutually neighboring individual thin wires (2) of superelastic metal are formed into a thin wire coarsely braided hose portion (4) provided with an interstice allowing passage of blood flow. The hoselike body when pulled in the longitudinal direction causes the individual thin wires (2) of superelastic metal to strech into fine gathering, and when released from pulling can make resilient restoration to the original hoselike body.

The invention discloses a balloon dilatation catheter, which comprises an outer tube, a reinforced tube, a balloon, an inner tube and a connector, wherein the reinforced tube penetrates through an inner cavity of the outer tube, a far end of the reinforced tube penetrates through the balloon and is hermetically fixed to a far end of the balloon, the reinforced tube is provided with a plurality of hollowed-out grooves, the inner tube penetrates through an inner cavity of the reinforced tube, a far end of the inner tube extends out of the far end of the reinforced tube and is hermetically fixed to the balloon, and the connector is fixed to a near end of the outer tube and provided with a first joint and a second joint. Compared with an existing integral reinforced tube, the balloon dilatation catheter not only can automatically and flexibly change bending angles according to practical bending of a blood vessel to fit the bending and changeable blood vessel and avoid damaging the blood vessel due to forcedly straightening the blood vessel, but also can avoid secondary damage to the blood vessel caused by pullback of the catheter with irreversible bending deformation after being acted by external force, and is beneficial to a blood vessel dilatation surgery.

A device to aid in establishing intravenous access by means of a sequential trapping and displacing of the venous blood in a top to bottom action down an extremity, resulting in a localized increase in the diameter of the veins, due to increased, trapped blood volume. The resulting distention of the vessels produces a stabilizing effect, thereby decreasing vascular mobility and rolling. The combination of vessel distention and stabilization greatly facilitates the obtaining of a patent I.V. The sequential trapping and milking of venous blood toward the extremity is accomplished via a specialized inflatable bladder.

The invention discloses nano-element traditional Chinese medicinal fabric antibacterial underwear for preventing and treating psoriasis, which belongs to the technical field of functional healthy fabric underwear production. Psoriasis is a skin disease which has high morbidity and stubborn disease process, is easy to relapse, is difficult to cure and does serious harm to the physical and psychological health of people. Far infrared heat effect takes effect in deep subcutaneous tissues through medical stone, tourmaline and a nano silver (Ag) antimicrobial agent, so the underwear expands blood vessels, quickens blood flow, increases cell activity and blood oxygen content, makes human bodies absorb more negative ions and trace elements, promotes body metabolism, enhances cellular immunity and humoral immunity of the human bodies, promotes the balance of elements in the human bodies, strengths the regeneration activity of cells and resists bacteria, cancers and inflammation. The underwear prevents and treats psoriasis when a user wears the underwear.

The present disclosure involves a rheolytic thrombectomy catheter with a self-inflating proximal balloon having drug infusion capabilities. A self-inflating balloon having a plurality of outflow orifices located about the peripheral circumference thereof is located proximal to an inflow gap or orifices and a fluid jet emanator and which balloon is inflated and expanded by internal operating pressures to uniformly space and position the outflow orifices of the self-inflating balloon in close proximity to or in intimate contact with the thrombus or walls of the blood vessel. Devices of the present disclosure can be used for the purposes of thrombectomies, embolectomies, thrombus or vessel dilation and for the delivery of drugs to a thrombus or vessel site.

The invention belongs to the technical field of medical instruments and particularly relates to a cardiovascular dilation device. The cardiovascular dilation device comprises a catheter, a dilator, guide heads, an air catheter and a compression cylinder. The catheter in a hollow tube shape and the guide heads at two ends of the catheter are formed integrally, and the dilator is mounted on the outer side wall of the catheter. By arrangement of the dilator formed by a mechanical structure, the compression cylinder drives slide seats of the dilator to slide, and arc supporting faces are supportedby supporting frames through a planar four-rod structure to realize blood vessel supporting while a sufficient gap is reserved to make it convenient for a doctor to dose and clear through the catheter. A driving device in the compression cylinder is provided with a damping guide rod to enable uniform speed and slowness in movement of a piston, an output shaft is driven to move by changing of airpressure, accurate control is realized, high stability of the mechanical supporting structure is achieved, and accordingly surgical smoothness can be guaranteed.

Linking Magnesium ions to Nitric Oxide precursor L-Arginine, chemically 2-amino-5-guanidino valeric acid, with a platelet aggregation inhibitor compound such as, but not limited to acetylsalicylic acid or clopidogrel bisulfate, unexpectedly results in a pharmaceutically stabilized compositions with extended shelf life to be taken orally to provide gradual release vasodilatory and anti-platelet aggregation pharmacological activity with reduced potential for producing gastrointestinal lesions. L-Arginine releases ADNO (Arginine derived Nitric Oxide) in the coronary artery epithelium as EDRF (endothelium dependent relaxing factor) to dilate the arteries to promote blood flow to the myocardium, and the platelet aggregation inhibitor such acetylsalicylic acid or clopidogrel and others of this class of drugs inhibits or antagonizes the aggregation adhesion of platelets in the blood stream. Aggregated or clumped blood platelets contribute to arterial stenosis due to formation of atherosclerotic plaques that occlude coronary and other circulatory arteries. In addition to coronary arteries, atherosclerotic plaques can occlude and stenose carotid arteries and femoral arteries due to aggregated or clumped blood platelets, and the subject of this patent discovery will also be of cardiovascular health benefit respectively in preventing carotid cerebrovascular accidents and femoral artery leg circulation disease.

The invention relates to a netty stent for endovascular treatment. An existing technical scheme for treating vascular dilation diseases by the aid of a netty stent includes that a plurality of netty metal stents are coaxially overlapped and metal thin wires are woven three-dimensionally, so that a three-dimensional netty stent is formed, the principle includes that the disorder state of blood in a dilated blood vessel cavity is changed by the netty stent, and lesions are promoted to be repaired by a natural blood coagulation mechanism. The technical scheme of the invention includes that on the basis of an existing vascular laminating film stent consisting of an elastic supporting frame and a laminating film, a flow limiting screen with a flexible three-dimensional structure is used for replacing the laminating film, and the supporting frame and the flow limiting screen are compounded internally and externally so as be connected integrally. The compound netty stent further can be manufactured into a separate combined type or integral branch stent. The compound netty stent has the advantages that the compound netty stent is easy in manufacture and flexible in implantation, and an anatomy channel of a lesion blood vessel can be recovered.

A method of treating cerebral vasospasm includes delivering at least a first blood vessel including an expandable segment to a position within a blocked or constricted portion of a vessel and transitioning the expandable segment from a collapsed configuration to an expanded configuration to dilate the vessel and to restore adequate blood flow through the vessel. The expandable segment has a pre-set outer diameter substantially equal to or less than an inner diameter of the vessel. Additionally, the expandable segment is configured to expand with a minimal amount of radial force necessary to contact and expand the inner walls of the vessel. After dilation of the vessel, the device is removed from the patient's body. If necessary, additional blood vessel dilation devices each including an expandable segment having a pre-set outer diameter greater than the previous device's expandable segment can be used in order of increasing pre-set outer diameter of the expanded segment to further dilate the blocked or constricted portion of the vessel and restore blood flow through the vessel. Once adequate blood flow through the vessel has been restored, the blood vessel dilation device is withdrawn.

The invention relates to traditional Chinese medicine for eliminating pain and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine for eliminating pain is prepared from such raw materials as musk, safflower carthamus, panax notoginseng, dragon's blood, incised notopterygium, ligusticum wallichii, asarum sieboldii, peach kernel, radix angelicae, cassia twig and the like by independently soaking, steaming, fermenting and distilling in groups and mixing. The traditional Chinese medicine disclosed by the invention has beneficial effects that the traditional Chinese medicine for eliminating pain is prepared from natural Chinese herbal medicines through a fermentation process; the traditional Chinese medicine, which can be smeared on or sprayed to an affected part, can rapidly permeate skin so as to accelerate tissue repair, relieve capillary dilation, cell edema, soft tissue injury, local inflammation and like problems, to effectively improve local edema, pain or dermal inflammation, provide nutrition to tissue cell regeneration or soft tissue recovery, offer effective help to bone joint lubrication and cell reconstruction, significantly shorten recovery time in patients with bone and joint diseases and relieve the feeling of pain.

The invention discloses a medicine eluting balloon catheter with a function of thrombus aspiration and vasodilatation, and belongs to the field of medical device. The catheter structure comprises a balloon cavity 1, an auxiliary cavity 2, a RX port 3, a guide wire cavity 4, a developing ring 5, a suction cavity 6 and a Y-type connector 7. The balloon cavity is in the outermost layer of the suctioncatheter, the auxiliary cavity 2 is on the inner wall of the suction cavity 6, and the guide wire cavity 4 is on the distal end inner wall of the suction cavity 6. The medicine eluting balloon catheter is used for medicine thrombolysis by injecting thrombolytic medicine into the suction cavity 6. The invention of the medicine eluting balloon catheter is set an auxiliary chamber on the inner wallof the suction cavity 6, applying the improved in vitro ultrasonic assisted thrombolysis (ETUS) function, and a small metal microporous cylinder is placed in human body by the auxiliary cavity 2 conveying system; the medicine eluting balloon catheter reflects multiple direction ultrasonic wave through in vitro ultrasonic probe ultrasound and porous cylinder to amplify ultrasonic cavitation effect,improving the efficiency of broken bolt, and feeds into the interference wire through the auxiliary cavity 2 to break the bolt with mechanical force.

The present invention relates to the Chinese herbal medicine preparation including digestion liquid inside common nepenthes bag as main medicine component and pharmaceutical acceptable supplementary medicine material and its preparation process and application. By means of the digestion liquid inside common nepenthes bag, the medicine, after being introduced into blood vessel, can dissolve the embolism, hardened clots and inflammation factor inside blood vessel, decompose fat, cholesterol, saccharide and other composite macro molecular compound, promote blood circulation and dredge microcirculation. In addition, the medicine has common nepenthes and pubescent holly root as auxiliary medicine component, and this makes the medicine safe and high in treating effect. The present invention may be used together with blood vessel dilating Western medicine for wide use in treating various cardiac and cerebral vascular diseases.

The invention discloses a cardiovascular internal medicine disease rehabilitation physical therapy device. The device comprises a bottom plate and a seat plate located above the bottom plate, whereinthe left end of the seat plate is fixedly connected with a backup plate through a support; two parallel vertical plates are fixedly installed at the top of the bottom plate located on the right side of the seat plate; a same rotating column is movably installed between the two vertical plates; the upper portions of the two vertical plates and the upper portion of the rotating column are rotationally connected through a same rotating shaft; and the top end of the rotating column is fixedly connected with a handle rod through a connecting rod. The upper limbs, the lower limbs and the whole bodyof a patient can be subjected to rehabilitation training, the meridian, nerve, blood and body fluid circulation among the upper limbs, the lower limbs and the joints of the whole body of the patient is promoted, the neurotrophic state is improved, vasodilation is promoted, and blood circulation is prevented from being blocked, so that the defect of long treatment period caused by an existing single treatment mode of only oral administration of medicines is avoided, the rapid recovery of the patient is facilitated, and the rehabilitation period is shortened.

The invention relates to a blood vessel expanding type vasodilator-stimulated phosphoprotein detection kit which comprises magnetic particles coated with VASP monoclonal antibodies, an enzyme workingsolution containing marked VASP-P monoclonal antibodies, a lysate and a reaction substrate. The kit is fast in detection speed, simple and convenient to operate, high in sensitivity, and good in specificity.

The invention provides an automatic intermittent traction device for improving body microcirculation and belongs to the technical field of body microcirculation medical apparatuses. The traction device has the advantages that according to the needs for decompression traction of patients, the automatic intermittent traction device for improving the body microcirculation is provided, the whole traction process is gentle and stable, the operation is easy, and leg rehabilitation physical therapy exercise is achieved; electromagnetic vibration reeds are installed at a bottom plate and the neck and waist of a pillow, so that when feeling cervical vertebra and waist aches, users can receive relaxing physical therapy in any time, and various ache symptoms are reduced; moreover, the arrangement of a biological magnetic fiber layer can generate the magnetic field effect on the human body so that veins expand, the blood flow velocity is increased, the function of the central nervous system is adjusted, and the human body immune function is improved. By the arrangement of a medical stone and an organic germanium fiber layer, microelements needed by the human body can be provided, body microcirculation is improved, the cell immunity is enhanced, and the role of preventing and treating various skin diseases is played.

The invention belongs to the field of traditional Chinese medicine production and relates to a traditional Chinese medicine uncaria extract, namely hirsutine analogue compound with the structure represented by formula (1) and application of the hirsutine analogue compound in the preparation of anti-hypertensive drugs. An experiment proves that the hirsutine analogue compound has remarkable pharmacological actions of resisting hypertension and vascular dilation. A spontaneously hypertensive rat (SHR) experiment proves that the blood pressure and the heart rate of an SHR are obviously decreased after 30 minutes of administration, and the blood pressure of the spontaneously hypertensive rat can be rapidly and effectively decreased; an in-vitro vascular ring vasomotion experiment proves that by virtue of an extremely low dose of the hirsutine analogue compound, the vascular ring contraction caused by phenylephrine can be remarkably dilated. The hirsutine analogue compound can be used as a raw material of a pharmaceutical preparation, is further used for preparing drugs for treating hypertension and is particularly used for preparing vascular dilation drugs for treating hypertensive emergencies.

There is provided a stent positioning system, including an inflatable balloon (22) for expanding a stent, the balloon, in its collapsed state, fitting into and being adapted to carry the stent in its pre-expanded condition; stent locator means slidably accommodated in a guide catheter and adapted to change its shape prior to making contact with the interior wall surface of a major blood vessel in the ostial region of a smaller blood vessel branching off from the major vessel and prior to the expansion of the stent, and mechanical means for changing the shape of the stent locator means; wherein the change of shape enables the locator means (14) to abut the interior wall surface, thereby ensuring correct apposition between the stent and the ostium of the smaller blood vessel.

The invention discloses a constraint support of a non-invasive balloon catheter. The constraint support comprises a main body portion which is of a tubular structure and used for covering the outer portion of the balloon catheter and fixing portions which are connected to the two ends of the main body portion and used for being fixedly connected with the balloon catheter, and the constraint support is used for expanding and shrinking along with the balloon catheter and restraining the maximum expanding volume of the balloon catheter. The invention further discloses a non-invasive vascular dilation device. The device comprises the balloon catheter and the constraint support which have compressed forms used for being placed into a blood vessel and expanded forms used for enlarging in the blood vessel respectively, the maximum diameter of the constraint support in the expanded form is smaller than that of the balloon catheter in the expanded form. According to the constraint support of the non-invasive balloon catheter and the non-invasive vascular dilation device, the structures are simple, use is convenient, the therapeutic effect is greatly improved, and damage to the blood vesseland the occurrence possibility of complications are reduced.