310 results about "Valeric acid" patented technology

The present invention relates to 25 hitherto undescribed genes of B. licheniformis and gene products derived therefrom and all sufficiently homologous nucleic acids and proteins thereof. They occur in five different metabolic pathways for the formation of odorous substances. The metabolic pathways in question are for the synthesis of: 1) isovalerian acid (as part of the catabolism of leucine), 2) 2-methylbutyric acid and / or isobutyric acid (as part of the catabolism of valine and / or isoleucine), 3) butanol and / or butyric acid (as part of the metabolism of butyric acid), 4) propyl acid (as part of the metabolism of propionate) and / or 5) cadaverine and / or putrescine (as parts of the catabolism of lysine and / or arginine). The identification of these genes allows biotechnological production methods to be developed that are improved to the extent that, to assist these nucleic acids, the formation of the odorous substances synthesized via these metabolic pathways can be reduced by deactivating the corresponding genes in the micro-organism used for the biotechnological production. In addition, these gene products are thus available for preparing reactions or for methods according to their respective biochemical properties.

Packaging laminate for packages for liquid foods having excellent liquid and oxygen gas barrier properties in which all included layers are biodegradable. The packaging laminate includes at least one liquidtight layer (11, 13) of homo or copolymers of monomers selected from a group consisting of lactic acid, glycol acid, lactide, glycolide, hydroxy butyric acid, hydroxy valeric acid, hydroxy caproic acid, valerolactone, butyrolactone and caprolactone, as well as an oxygen gas barrier layer (12) of ethylene vinyl alcohol, polyvinyl alcohol, starch or starch derivatives. The oxygen gas barrier layer is preferably applied by a dispersion coating process. The layers may be laminated directly to one another or indirectly by means of interjacent adhesive layers. The packaging laminate may also include a core layer of, for example, paper or paperboard, or a biopolymer. The invention also realises a method of producing the biodegradable packaging laminate according to the invention.

A climb-up pitfall trap for attracting and capturing bed bugs and the like comprises a rough exterior surface, a precipice, a smooth interior surface and sensory lures. The sensory lures include heat, carbon dioxide and / or a lure composition. The lure composition comprises a combination of (a) L-lactic acid, and (b) a fatty acid from the group consisting of (1) propionic acid, (2) butyric acid, and (3) valeric acid. The lure composition may also comprise (c) octenol. A method for attracting and capturing bed bugs and the like uses the climb-up pitfall trap in a bed bug infested environment.

The invention relates to a composite soil conditioner, comprising biogas residues, pyroligneous acid, mineral powder, soluble chitosan, diethylene triaminepentaacetic acid pentasodium, a surfactant, tobacco powder, trehalose, di-rhamnolipid, a flocculating component, a penetrating agent, enteromorpha powder, modified zeolite, boron-zinc-magnesium-containing fungicide, a nano additive, an accelerant, pentaerythritol triacrylate and ionic liquid, preferably also comprising 4-methyl phenyl valerate which is equal to the ionic liquid in weight. The novel composite soil conditioner has excellent soil improvement and recovery performance, the utilization rate of the fertilizer by the crop is greatly increased, and the composite soil conditioner can significantly increase the yield, simultaneously also can improve the permeability of the soil and avoids side effects of heavy metals such as cadmium; thus, the composite soil conditioner is beneficial to crop growth and has a wide industrial application prospect.

The invention provides an esterification method of pentaerythritol, which comprises the following step: under the action of a tin catalyst, carrying out esterification reaction on pentaerythritol and saturated fatty acid to obtain pentaerythritol ester, wherein the saturated fatty acid is one or more of butyric acid, valeric acid, hexanoic acid, heptylic acid, octanoic acid, pelargonic acid and capric acid. The esterification method provided by the invention has the advantages of higher product yield, higher product quality, simple esterification after-treatment and low pollution. The experimental result indicates that the conversion rate of the esterification reaction is greater than 99.5%, and the hydroxyl value in the reaction product is lower than 1mg KOH / g.

The invention discloses freezer oil and work fluid composition for a freezer. Freezer oil of the invention comprises more than 10 mass percentage ester based on total amount of freezer oil and used with dichloromethane refrigerant, wherein the ester is ester of dipentaerythritol and fatty acid; the proportion of 2-methyl valeric acid in fatty acid is more than 20 mol%. Moreover, work fluid composition for the freezer of the invention comprises freezer oil of the invention and dichloromethane refrigerant.

A powder for use in cosmetic and personal care products containing ultrafine polyhydroxyalkanoate (PHA), ultrafine polyhydroxybutyrate (PHB), or ultrafine polyhydroxybutyrate-co-hydroxyvalerate (PHBV).

The invention discloses a novel esterase as well as a coding gene and an application of esterase. The esterase EST04211 has an amino acid sequence shown in SEQ ID NO. 2. The amino acid sequence of the gene of the esterase EST04211 is shown in SEQ ID NO. 1. The novel esterase disclosed by the invention is obtained by cloning Bacillus SCSIO15121 derived from deep sea of the Indian Ocean. The esterase has the largest characteristic that the esterification rate is 97% in catalytic synthesis of ethyl isobutyrate, and under similar conditions, the esterase can also catalyze propionic acid, butyric acid, valeric acid, caproic acid and ethanol, propanol, butanol, pentanol and hexanol to synthesize corresponding short-chain aromatic ester flavors, such as ethyl propionate, propyl propionate and butyl propionate, the esterification rate mostly reaches 85%-95%. The esterase can be applied in the industrial bio-manufacturing of the short-chain aromatic flavors, such as ethyl isobutyrate and the ester flavors are high in quality, belongs to natural products and can be applied in production industries, such as foods, cigarettes and daily chemical products.

The present invention discloses a method for separating a liquid chromatogram of the amino acid contented in tobacco and the product thereof. The method comprises the procedures of preparing an extraction liquid of the sample to be measured; and taking an A phase 99%water-1%ethane nitrile-0.1%nonafluoro valeric acid and a B phase 10%water-90%ethane nitrile-0.1%nonafluro valeric acid as a flowing phase gradient for elution and separation on the HyPURITY C18 reverse-phase chromatographic column. Aiming at the disadvantage of the method for analyzing the content of amino acid contended in tobacco and the product thereof, the invention accurately limits the condition of the liquid chromatogram analysis and provides an integral and whole experiment plan for obtaining an excellent chromatographic peak shape and an appropriate color spectrum runtime. Furthermore, the isomeride of the amino acid can be facilitated to obtain a base line separation. The chromatogram separation method provided by the invention can obtain an accurate analyzing result to the content of the amino acid in tobacco and the product thereof when combined with a mass spectrometric detection.

This invention relates to a manufacturing technique of organic compounds, or a preparation method for 5-bromo-valeric acid. Based on the method dry hydrogen bromide gas is going through a delta-valerolactone containing organic solvent, the ring of delta-valerolactone is easy to have cleavage reaction, corresponding 5-bromo-valeric acid is produced with high yield. As 5-bromo-valeric acid is hard to dissolve in alkanes, cycloalkanes and aromatic compounds solvents, cooling it below 30 DEG C, lower than the melting point of 5-bromo-valeric acid, 5-bromo-valeric acid crystallized and deposited. Then, 5-bromo-valeric acid solid with high purity is separated through filtration technique. This method has simple technique, easy to form scaled production, with wide application prospect and good economic benefit.

The invention discloses an aerated concrete block capable of adsorbing toxic and harmful gases and a preparation method of the aerated concrete block. The aerated concrete block is prepared from the following raw materials in parts by weight: 42-68 parts of yellow sands, 10-15 parts of nano black stones, 12-16 parts of a zeolite molecular sieve, 18-26 parts of allophone, 22-28 parts of wood dust, 15-20 parts of ground calcium carbonate powder, 26-34 parts of sea mud, 16-22 parts of attapulgite, 10-15 parts of alpha type semi-hydrated gypsum, 3-6 parts of carbomer resin, 1-2 parts of modified aluminum powder, 2-3 parts of sodium thiosulfate, 2-3 parts of zinc sulfate and 1-2 parts of azodiisobutyronitrile. The substances including the nano black stones, the zeolite molecular sieve and the like with outstanding physical adsorption functions are added into the aerated concrete block disclosed by the invention, so that the aerated concrete bock can adsorb harmful gases of formaldehyde, benzene compounds, sulfur oxide, nitrogen oxide, carbon monoxide, hydrogen sulfide, ammonia, isovaleric acid, methyl mercaptan, trimethylamine (fishy), TVOC (total volatile organic compounds) and the like to achieve a function of purifying air; and meanwhile, the aerated concrete block has the characteristics of high strength, good heat insulation and heat preservation properties, good sound isolation effect, heat resistance, moisture resistance, acid and alkali corrosion resistance and the like, and has a broad market prospect.

The invention discloses preparation and application of an ATP fluorescent probe for positioning mitochondria, wherein the probe has the structural formula defined in the specification and is synthesized by rhodamine B, diethylenetriamine, 5-bromo-valeric acid and triphenylphosphine as raw materials. In the system, ATP induces ring opening of a rhodamine lactam structure, strong fluorescence is produced, and high sensitivity is showed on ATP detection. At the same time, the probe shows good selectivity on the ATP, and is hardly interfered by other biological anions or inorganic anions. When the pH value is 6.0-8.0, ATP determination of the probe is not affected. In addition, the probe can be positioned in the mitochondria, and changes of the content of the ATP in the mitochondria are real-timely monitored.

Linking Magnesium ions to Nitric Oxide precursor L-Arginine, chemically 2-amino-5-guanidino valeric acid, with a platelet aggregation inhibitor compound such as, but not limited to acetylsalicylic acid or clopidogrel bisulfate, unexpectedly results in a pharmaceutically stabilized compositions with extended shelf life to be taken orally to provide gradual release vasodilatory and anti-platelet aggregation pharmacological activity with reduced potential for producing gastrointestinal lesions. L-Arginine releases ADNO (Arginine derived Nitric Oxide) in the coronary artery epithelium as EDRF (endothelium dependent relaxing factor) to dilate the arteries to promote blood flow to the myocardium, and the platelet aggregation inhibitor such acetylsalicylic acid or clopidogrel and others of this class of drugs inhibits or antagonizes the aggregation adhesion of platelets in the blood stream. Aggregated or clumped blood platelets contribute to arterial stenosis due to formation of atherosclerotic plaques that occlude coronary and other circulatory arteries. In addition to coronary arteries, atherosclerotic plaques can occlude and stenose carotid arteries and femoral arteries due to aggregated or clumped blood platelets, and the subject of this patent discovery will also be of cardiovascular health benefit respectively in preventing carotid cerebrovascular accidents and femoral artery leg circulation disease.

The invention discloses a processing technology of an air filtration membrane, which comprises the following steps: preparing the following substances by weight: polyethylene terephthalate, polypropylene, polyethylene, polyamide, cellulose acetate, cellulose acetate ethylene terephthalate, polypropylene, polyethylene, cellulose acetate, polyhydroxybutyrate Mix the acid copolyester and sodium dodecyl sulfonate, stir and mix the mixture again, and let stand for 1-2 hours in an environment of 40-45 degrees Celsius; the film is placed in an environment of 80-95 degrees Celsius and stand for 8-10 (8) After curing, it is lowered to room temperature and left to stand for 24 hours to obtain a filter membrane, which has good filtering effect, low cost and simple process flow.

The invention discloses a low-tar cigarette flavoring essence with organic acids. The cigarette flavoring essence is a mixture of the following raw materials in percentage by weight: 1%-2% of 0.1% formic acid, 2%-4% of 0.1% acetic acid, 0.05%-0.2% of 0.1% benzoic acid, 0.2%-0.4% of 0.1% isobutyric acid, 0.05%-1.5% of 0.1% valeric acid, 0.1%-0.2% of 0.1% isovaleric acid, 0.1%-0.4% of 0.1% phenyl acetic acid, 1.0%-2.0% of 0.1% beta-mevalonic acid, 1.5%-2.5% of 0.1% alpha-methylbutyric acid, 0.2%-0.5% of 0.1% hexanoic acid, 1.0%-3.0% of DL-tartaric acid, 2.0%-6.0% of malic acid, 0.05%-1.5% of lactic acid, 0.5%-2.5% of citric acid, 0.5%-2.0% of 10% levulinic acid, 36.3%-69.75% of distilled water and 20%-35% of propylene glycol. Due to the use of organic acid raw materials, the effect of the blended essence is promoted greatly; the problems such as high irritation, rough smoke, uncomfortable aftertaste and insufficient aroma, existing in the existing low-tar cigarette, are covercome remarkably; the smoking quality of the low-tar cigarette is enhanced.

The invention discloses a synthesis method of a structurally specific salbutamol complete antigen and belongs to the technical field of biochemical engineering. The synthesis method comprises the following steps: dissolving 2-bromo-1-[4-hydroxy-3-(hydroxymethyl)phenyl]aceto-1-ketone in acetone; after adding potassium carbonate, reacting with dibenzylamine to generate a compound B; generating a compound C under catalysis of lithium aluminium hydride; reacting with hydrogen under catalysis of Pd / C to generate a compound D; performing a reductive amination reaction with ethyl levulinate to generate a compound E; and hydrolyzing under alkaline condition, and recrystallizing to generate salbutamol hapten named as 4-((2-hydroxy-2-(4-hydroxy-3-(hydroxymethyl)phenyl)ethyl) amino) valeric acid. A complete antigen is obtained by coupling the carboxyl on the hapten and amidogen on carrier proteins. Experimental results show that the antiserum titer of animals immune to the complete antigen achieves 81,000, the limit of detection is 0.3ng / mL, and half inhibiting concentration is 3.2ng / mL; a generated antibody is high in specificity and sensitivity; the antigen or the antibody has a broad application prospect.

The invention discloses a method for mensurating relevant substances in sodium di-vedproate, The method comprises the following steps: sodium di-vedproate in a solid state is converted into valproic acid in a liquid state; a sodium di-vedproate sample is prepared; and according to contrast substances of butyric acid, valeric acid, diallyl acetic acid and (R,S)-2-isopropyl valerate, the relevant substances in the sodium di-vedproate are detected by a gas chromatograph instrument. The method can carry out relevant substances inspection on the sodium di-vedproate which exists in tablet dosages, capsule dosages, granular dosages, oral liquid dosages, needle dosages, film dosages, aerosol dosages or injection dosages and other dosages of a slow-release type, a controlled-release type and a common type, improve the quality standard of the prior sodium di-vedproate, and provide evidence for instituting a mensuration standard for the relevant substances of the sodium di-vedproate.

The invention discloses a blended type thick broad-bean sauce essence. The blended type thick broad-bean sauce essence is prepared from 3-methylthio propanol, 3-(methylsulfanyl)propanal, ethyl lactate, ethyl caprylate, hexanal, benzaldehyde, acetic acid, propionic acid, butyric acid, isovaleric acid, caproic acid, octoic acid, piperonal, furanone, furfural, 5-methylfurfural, 4-ethylguaiacol, butyl alcohol, 1-octen-3-ol, 2,5-dimethylpyrazine, 2,3,5-trimethylpyrazine, methyl cyclopentenolone and propylene glycol. The invention further provides a preparation method of the blended type thick broad-bean sauce essence. Blending is performed according to the proportion of the formula, and the thick broad-bean sauce essence which is coordinating in aroma, vivid in flavor and mellow is obtained.

The invention provides green apple essence used for water-based ink. The green apple essence is prepared from, by weight, 1-30% of green apple flavor, 5-55% of composite modified oligosaccharide and deionized water. The green apple flavor is prepared from ligustral, leaf alcohol, cis-3-hexenyl acetate, cis-3-hexenyl isovalerate, trans-2-hexenal, trans-2-hexenyl acetate, styralyl propionate, linalool, linalyl acetate, fructone, peach aldehyde, isoamyl isovalerate, isoamyl acetate, allyl caproate, sweet orange oil, acetic acid, acetic acid, geranyl acetate, damascene, benzyl acetate, lilial, cedryl acetate, acetoxy-2-tert-butylcyclohexane, ethyl acetoacetate, tonkalide, galaxolide and ethyl alcohol. Composite modified oligosaccharide serves as a wall material for wrapping green apple essence, green apple nanometer capsule slow-release essence is formed, and therefore the fragrance holding property and the water solubility of the essence are improved, and the green apple essence is suitable for perfuming of water-base ink.

The invention relates to the field of materials, and particularly discloses an immobilized material, a biological denitrification material, a preparation method and application. The immobilized material is prepared from the following raw materials: polyvinyl alcohol, sodium alginate and poly(hydroxybutyrate-co-3-hydroxyvalerate) (PHBV). The prepared immobilized material can be added into denitrifying bacteria to prepare the biological denitrification material, and the denitrification effect can be remarkably improved. Meanwhile, the PHBV has the effect of providing a carbon source in denitrification, and the denitrification efficiency can be improved in aquaculture wastewater. Moreover, the preparation method provided by the invention is simple, is capable of improving the denitrificationcapacity of immobilized denitrifying bacteria in low-carbon-nitrogen-ratio wastewater by adding the PHBV, and solves the problems that: existing immobilized materials generally cannot play a role of acarbon source, and denitrifying microorganisms in the low-carbon-nitrogen-ratio wastewater are likely to be incapable of denitrifying due to insufficient carbon source.

The invention discloses a tobacco flavor with natural sweet fruity aroma characteristics and a preparation method thereof. The method comprises the following steps: ethyl butyrate, ethyl isovalerate, butyl acetate and fruit extracts are uniformly mixed, the flavor is prepared, and the flavor can be dissolved into a solvent with any proportion for usage; and the flavor is applied to a tobacco product for endowing cigarettes with the natural sweet fruity aroma characteristics. The tobacco flavor aroma is coordinated with tobacco aroma, in order to improve smoking quality of cigarettes and improve comfort level for sense organs.

Pharmaceutical compositions comprising a valproic acid drug compound, providing modified release of the drug.

This invention relates to a method for preparing cobalt salt adherence accelerator, which can make cobalt salt product form a network molecular structure, thus improving the crosslinking acceleration performance of the product in rubber products. The cobalt salt adherence accelerator is composed of: 2-octanol solvent 30-50 parts, Co(OH)2 31.54-33.2 parts, decanoic acid 56-65 parts, mixed valeric acid 10-15 parts, and mixed acetic acid and propionic acid 5-8 parts. The method comprises: adding the raw materials into a reaction kettle, stirring, heating to 80-85 deg.C, reacting for 2 h, heating to remove water and solvent, and distilling at 170-190 deg.C and below 0.05 MPa to remove the trace solvent and unreacted materials.

The invention discloses a cigarette filter stick additive and application thereof to a cigarette filter stick. Triacetin is used as solvent, and ethyl acetate, 3-methyl valeric acid, 3-methyl glucose valerate, linalyl acetate and linalool are added into the solvent to be mixed and prepared into the cigarette filter stick additive and account for 0.010-0.050%, 0.005-0.020%, 0.005-0.020%, 0.01-0.007% and 0.001-0.007% of the weight of triacetin respectively in weight; the cigarette filter stick additive is uniformly sprayed into cigarette filter stick tows by the ratio of 6.0-8.0% of the weight of the cigarette filter stick tows to prepare the cigarette filter stick. The cigarette filter stick additive is used for the cigarette filter stick, has the advantages of emitting fragrance stably and keeping the fragrance for a long time, and can soften smoke, promote cigarette fragrance quality and improve the smoking quality of cigarettes.

The invention discloses a method for preparing 3,3,3-trifluoro-propionaldehyde, which aims to solve the problem of low reaction yield in the prior art. The method comprises the following steps of: putting 3,3,3-trifluoropropenyl methyl ether serving as a raw material, valeric acid and a solid super acidic catalyst into a reaction flask and reacting at the temperature of between 50 and 120 DEG C for 6 to 15 hours; and after the reaction is finished, cooling, filtering and separating the catalyst, and distilling to obtain the 3,3,3-trifluoro-propionaldehyde, wherein the solid super acidic catalyst is in an amount which is 3 to 10 percent based on the mass of the 3,3,3-trifluoropropenyl methyl ether, a molar ratio of the 3,3,3-trifluoropropenyl methyl ether to the valeric acid is 0.8-1.8:1; and the solid super acidic catalyst is mesoporous sulfonic acid, K-10 montmorillonite, a supported zirconia catalyst or a supported heteropolyacid catalyst. The method is mainly used for synthesizing the 3,3,3-trifluoro-propionaldehyde.

The invention discloses trans-N-(4-hydroxyl-3-methoxybenzy)-8-methyl-5-nonenamide which has a structural formula as shown in a formula (1). The trans-N-(4-hydroxyl-3-methoxybenzy)-8-methyl-5-nonenamide is prepared by the following steps of: carrying out a single bromination reaction on pentanediol to generate 5-bromo-pentanol; oxidizing the 5-bromo-pentanol to generate 5-bromo-valeric acid; reacting the 5-bromo-valeric acid with triphenylphosphorus to generate (5-carboxyl-amyl)triphenylbromophosphine; reacting the (5-carboxyl-amyl)triphenylbromophosphine with isovaleraldehyde to generate cis-8-methyl-5-nonenoic acid; reacting the cis-8-methyl-5-nonenoic acid with a sodium nitrite / nitric acid solution to obtain trans-8-methyl-5-nonenoic acid; reacting the trans-8-methyl-5-nonenoic acid with an acetylation reagent to obtain trans-8-methyl-5-enoic acid chloride; reacting vanillin with ammonium formate to obtain vanillic amine; acidizing the vanillic amine and neutralizing with alkali liquor; and then reacting the mixture with the trans-8-methyl-5-enoic acid chloride to obtain the trans-N-(4-hydroxyl-3-methoxybenzy)-8-methyl-5-nonenamide. The invention has the advantages of simple and convenient process and mild reaction conditions; and the prepared product provides a new development space for the research on capsaicin substances. The formula (1) is described in specification.

The invention provides an interference repellent for leguminivora glycinivorella, and also discloses a preparation method for the interference repellent. The interference repellent is prepared from leaf alcohol, cis-3-hexenyl acetate, cis-3-hexenyl ester n-valerate, (E)-butyric acid-3-hexenyl ester, ocimenum, (Z)-propionic acid-3-hexenyl ester, alpha-farnesene, methyl jasmonate, n-hexane or dimethylbenzene and the like. The interference repellent has reasonable components, is an environment-friendly biological interference repellent, has a simple preparation method and a good prevention and control effect, is safe for crops and natural enemies, cannot make insects generate resistance, is environment-friendly and convenient to apply and popularize, and has a wide market prospect and obvious economic, ecological and social benefits.

The invention relates to a method for extracting n-butyric acid, valeric acid and hexoic acid from lyechange as a by-product of cyclohexanone production. The method comprises the following steps: carrying out preprocessing on a sodium sulfate aqueous solution; preprocessing the evaporated mother liquor; conveying slurry in a concentration jar for concentration; washing the concentrated salt with a small amount of water; discharging the water for washing and the crystallization water into a delamination jar of the sodium sulfate aqueous solution through an outlet of the concentration jar; discharging the concentrated salt into a centrifugal machine for centrifugal dehydration from the concentration jar; self-flowing water dehydrated from the centrifugal machine into the delamination jar of the sodium sulfate aqueous solution through high order difference; re-separating organic matters in the crystallization water and the water dehydrated from the centrifugal machine; carrying out warming and reduced pressure distillation on saponifiedoil by using an enamelstill, a stainless steel kettle or a film evaporator; adding a reasonable amount of lower alcohol into the tail oil obtained by distilling monobasic acid; and carrying out esterification reaction on the tail oil and conversing the remained organic acid into esters.