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69 results about "Blood Coagulation Factor X" patented technology

Coagulation factor X (10) is a man-made protein similar to a natural protein in the body that helps the blood to clot. Coagulation factor X is used to treat or prevent bleeding in people with hereditary factor X deficiency.

Method for efficiently extracting and purifying blood coagulation factor IX and blood coagulation factor X

The invention provides a method for efficiently extracting and purifying a blood coagulation factor IX and a blood coagulation factor X. The method provided by the invention comprises the following steps: collecting blood, treating, and collecting blood plasma; and extracting an IX crude extract and an X crude extract from the blood plasma, and purifying. The method is characterized in that the purifying step is to use FIX / FX-bp-Sepharose 4B to purify the blood coagulation factor IX crude extract and the blood coagulation factor X crude extract respectively through the affinity chromatography; and the affinity ligand FIX / FX-bp is selected from ACF I, ACF II or AHP. The purified blood coagulation factor IX can be directly used as a medicament and the purified blood coagulation factor X canbe directly used as a reagent.
Owner:UNIV OF SCI & TECH OF CHINA
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