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Application of cannabinoid compounds in the treatment of neurodermatitis

A compound and cannabinoid technology, applied in the field of medicine, can solve the problems of verification of the effect of THC or cannabidiol, and it is difficult to clarify the effect of THC or cannabidiol.

Inactive Publication Date: 2019-01-15
HANYI BIO TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above-mentioned prior art only briefly lists the therapeutic uses of the composition, and the instructions do not specifically verify the role of THC or cannabidiol in neurodermatitis, and the composition in US2014302086 also contains other substances that can It is difficult to clarify the effect of THC or cannabidiol on the ingredients for relieving neurodermatitis, that is, it cannot be clearly concluded from the above-mentioned prior art that CBD or THC can treat neurodermatitis

Method used

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  • Application of cannabinoid compounds in the treatment of neurodermatitis
  • Application of cannabinoid compounds in the treatment of neurodermatitis
  • Application of cannabinoid compounds in the treatment of neurodermatitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] Example 1 Capsule unit dosage form

[0064] Prescription ingredient: Cannabidiol 200mg

[0065] Microcrystalline Cellulose 90mg

[0066] Pregelatinized starch 100mg

[0067] Croscarmellose 7mg

[0068] Magnesium stearate 0.5mg

[0069] Preparation method: the active ingredient is sieved, mixed with auxiliary materials, and packed into hard gelatin capsules.

Embodiment 2

[0070] Example 2 Capsule unit dosage form

[0071] Prescription Ingredients: Cannabidiol 400mg

[0072] Microcrystalline Cellulose 100mg

[0073] Pregelatinized starch 150mg

[0074] Croscarmellose 10mg

[0075] Magnesium stearate 0.2mg

[0076] The preparation method is the same as in Example 1.

Embodiment 3

[0077] Example 3 Tablet unit dosage form

[0078] Prescription ingredient: THC 100mg

[0079] Dextrin 100mg

[0080] Microcrystalline Cellulose 25mg

[0081] Polyvinylpyrrolidone 10mg

[0082] Sodium carboxymethyl starch 15mg

[0083] Magnesium Stearate 1mg

[0084] Preparation method: sieve the active ingredient, mix it with dextrin, microcrystalline cellulose, polyvinylpyrrolidone and sodium carboxymethyl starch until a uniform mixture is formed, sieve the mixture, and mix it with magnesium stearate. The resulting powder mixture is then compressed into tablets of the desired shape and size.

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Abstract

The invention discloses the use of cannabinoid compounds or pharmaceutically acceptable salts thereof in the preparation of pharmaceutical compositions for the treatment of neurodermatitis, wherein the cannabinoid compounds can be selected from one of tetrahydrocannabinol, cannabinol, hypocannabinol and tetrahydrocannabinol, or the cannabinoid compounds can be selected from the group consisting of(1) a combination of tetrahydrocannabinol and tetrahydrocannabinol; (2) a combination of cannabinol and hypocannabinol; (iii) a combination of tetrahydrocannabinol and hypocannabinol; (4) a combination of cannabinol and tetrahydrocannabinol; (5) a combination of cannabinol, hypocannabinol and tetrahydrocannabinol; (6) a combination of tetrahydrocannabinol, hypocannabinol and tetrahydrocannabinol.

Description

technical field [0001] The invention relates to the field of medicine, in particular to the application of a composition containing one or more than two cannabinoid compounds in the treatment of neurodermatitis. Background technique [0002] Neurodermatitis, also known as lichen simplex chronicus, is a skin disease with limited skin nerve dysfunction. It is a chronic skin disease characterized by paroxysmal pruritus and lichenification of the skin. The etiology is still unclear, but it is generally believed that it is related to long-term scratching, friction, neuropsychological factors and some external stimuli. Among them, mental factors are currently considered to be the main cause of this disease. Mood swings, excessive mental stress, anxiety, Sudden changes in the living environment, etc. can make the condition worse and repeated. At present, in the clinical treatment of neurodermatitis, histamines, calcium, etc. are often used to relieve itching, supplemented by oral...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/353A61K31/352A61K31/05A61P17/00A61P17/04A61P25/00
Inventor 张可谭昕常坦然金倩
Owner HANYI BIO TECH CO LTD
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