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An External use medicine for treating skin pigment reduction and its preparing method

A technology for topical drugs and skin pigments, applied in the field of topical drugs for the treatment of skin diseases, can solve the problems of long treatment period, poor curative effect, side effects, etc.

Inactive Publication Date: 2007-04-11
成中田
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are many methods and medicines for treating this disease today, they cannot achieve the ideal curative effect. For example, the treatment methods and medicines such as "ultraviolet therapy" and "vitiligo net" medicines not only have disadvantages such as poor curative effect, slow effect, and long treatment period, but also There are also varying degrees of side effects
Chinese patent CN1066182A discloses an artificial brown dihydroxyacetone emulsion composition, which only produces a temporary brown color on the skin and cannot treat vitiligo

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Put pharmaceutical grade alcohol, Polygonum multiflorum, Psoraleae, Sophora japonica, and dihydroxyacetone into a glass tank according to the weight listed in Table 1, mix and place for 15 days, and then use commercially available filter equipment in a sterile environment to filter The medicinal liquid is filtered to obtain 30 kg of pure medicinal liquid. It can also be refilled into 10ml plastic bottles for later use.

Embodiment 2

[0028] Embodiment 2 manufacture step is identical with the step of embodiment 1, and difference is that its consumption is as shown in (embodiment 2) in table 1, wherein the net pure medicinal liquid that obtains is 65 kilograms.

Embodiment 3

[0030] The manufacturing step of embodiment 3 is identical with the step of embodiment 1, and difference is that its consumption is as shown in (embodiment 3) in table 1, wherein it is 128 kilograms to obtain pure medicinal liquid.

[0031] Example 1

Example 2

Example 3

Alcohol (kg)

60

100

200

Polygonum multiflorum (kg)

6

10

25

Psoralen (kg)

6

10

20

Sophora rice (kg)

8

15

25

Dihydroxyacetone (kg)

0.6

1

2

Obtained net medicinal solution (kg)

30

65

128

[0032] The present invention provides example 3 and the clinical observation results of external drug curative effect for the treatment of skin hypopigmentation are as follows:

[0033] From March 2000 to March 2004, the National Sixty-ninth Specialized Disease Research Institute and two hospitals of Dingzhou Vitiligo Hospital in Hebei Province used...

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Abstract

This invention relates to an external use medicine for treating skin pigment reduction and its preparing method. This external use medicine is prepared by using alcohol, radices polygoni multiflori, fructus psoraleae, flos sophorae immaturus, dioxyacetonem through refining. The medicine has the strongpoint of fast effectiveness, high curative effect, innocuity, no side-effect, convenience in use and low price, especially suitable for treatment of vitiligo.

Description

technical field [0001] The invention relates to a medicine for external use for treating skin diseases, in particular to a medicine for external use for treating skin hypopigmentation and a preparation method thereof. Background technique [0002] Skin hypopigmentation is a common skin disease, which is relatively common and widely distributed. The incidence rate accounts for about 7 / 1000 of the world's population. In recent years, the incidence rate has been on the rise. Although there are many methods and medicines for treating this disease today, they cannot achieve the ideal curative effect. For example, the treatment methods and medicines such as "ultraviolet therapy" and "vitiligo net" medicines not only have disadvantages such as poor curative effect, slow effect, and long treatment period, but also There are also varying degrees of side effects. Chinese patent CN1066182A discloses an artificial brown dihydroxyacetone emulsion composition, which only produces a tempo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/704A61K9/08A61P17/00
Inventor 成中田
Owner 成中田
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