141 results about "Dihydroxyacetone" patented technology

A composition is provided which is useful for self-tanning skin coloring and is characterized by improved stability, which comprises from about 0.5% to about 20.0% by weight, based on total weight of said composition, of a self-tanning skin coloring agent subject to chemical instability, which is preferably dihydroxyacetone; from about 2.0% to about 40.0% by weight of a polyethoxyglycol, which is preferably ethoxydiglycol; and from about 0.1% to about 15.0% by weight of a polyol comprising a polyhydric compound having at least three hydroxyl groups and at least three carbon atoms, which is preferably D-sorbitol. The self-tanning composition may further optionally contain from about 0.1% to about 8.0% by weight of a water soluble dihydroxyl compound having at least two, and up to eight carbon atoms, which is preferably ethylene glycol; and the self-tanning composition may still further optionally contain an acidifying agent in amount sufficient to maintain the pH of said total composition at from about 3.5 to about 4.5, which is preferably sorbic acid. Cosmetologic products and methods of tanning are also provided.

The invention discloses water-soluble polyurethane for the wood lacquer and a preparation method thereof. The water-soluble polyurethane comprises the following raw materials in parts by weight: 165-175 parts of polycarbonate diol, 131-132 parts of isophorone diisocyanate, 0.4-0.6 part of catalyst, 16.5-17.5 parts of dihydromethyl propionic acid, 2.7-3 parts of dihydroxyacetone, 18.5-19.5 parts of 1,4-butanediol, 4-5 parts of acetone, 12.5-13 parts of triethylamine, 6-7 parts of ethylenediamine, 628-638 parts of deionized water and 5-6 parts of adipic acid dihydrazide. The preparation method adopts the preparation technology combining the acetone method with pre-polymer dispersion method, thus effectively reducing the dosage of acetone and increasing the molecular weight of the generated polyurethane; and when the prepared water-soluble polyurethane dispersion forms a film, with the volatilization of water and the reduction of the pH value, the self-crosslinking reactions of ketonic carbonyl and hydrazide group can be performed, thus the after crosslinking density of the film can be increased and the hardness and water resistance of the the film can be increased.

Methods of converting cellulose or related biorenewable carbohydrate materials into high-value chemical compounds. The methods provide a means of converting low-cost materials such as cellulose and biomass into high yields of compounds such as ethylene glycol, propylene glycol, glycerin, methanol, hydroxyacetone, glycolaldehyde and dihydroxyacetone.

The invention discloses a method for producing 1,3-dihydroxyacetone through catalytic oxidation with a supported gold catalyst. According to the method, a glycerin aqueous solution and oxygen are used as raw materials, ZnO, Cu-Al hydrotalcite or spinel supported gold is used as the catalyst, and high selectivity conversion from glycerin to the 1,3-dihydroxyacetone in an oxidation manner is realized in the absence of alkali. The method is performed in the absence of alkali, has low requirement for reaction equipment and is low in investment; the catalyst preparation technology is simple, reaction raw materials are easy to obtain, the reaction process is mild, the method is environment-friendly and free of pollution, the catalyst has advantages of convenience in recovery, long service life and the like, and the industrial prospect is bright.

The invention describes a process for the production of glycerol of providing a vegetable oil or fat as starting material, obtaining crude glycerol from the vegetable oil or fat, and treating the crude glycerol with a reducing agent. The present invention also describes a process for the production of a medicament or pharmaceutical composition, the medicament or composition formed by combining glycerol and at least one pharmaceutically active ingredient. The present invention also describes a pharmaceutical composition or medicament composed of glycerol obtained by way of the invention and a pharmaceutically active ingredient, which compositions forms very little glyceraldehyde and dihydroxyacetone during storage.

Chemically protected dihydroxyacetone and / or dimers are used to make polycarbonates, poly(acetal carbonate)s, poly(spiroacetal)s, polyesters and polyurethanes.

The invention discloses a leucoderma covering agent. The leucoderma covering agent is a covering liquid or covering cream, wherein the covering liquid mainly comprises 1,2-propyleneglycol, jojoba oil, a preservative, a surfactant, vitamin E acetate, 1,3-dihydroxyacetone, an edible pigment and deionized water; and the covering cream mainly comprises magnesium aluminum silicate, 1,2-propyleneglycol, methyl parahydroxybenzoats, propyl p-hydroxybenzoate, imidazolidinyl urea, talcpowder, titanium dioxide, iron oxide, jojoba oil, vegetable fat, vitamin E acetate, stearyl alcohol, stearic acid, decapolyglycerol monooleate, diolein, triethanolamine and deionized water. The covering liquid has waterproof, sweatproof and wear-resistant effects, and is durable; the covering cream is quick in coloration and natural in color formation, and is convenient to use; and the covering liquid and the covering cream are combined to provide comprehensive covering for leucoderma patients.

The invention discloses a new method for preparing 1, 3-dihydroxyacetone from glycerol, which comprises the following steps: (1) acetalation reaction, which is to perform acetalation reaction of the glycerol and benzaldehyde in the presence of a water-carrying agent and under the action of an acid catalyst A so as to obtain glycerol benzaldehyde acetal ester having a structure as shown in the formula (I); (2) oxidation reaction, which is to oxidize the glycerol benzaldehyde acetal ester in an organic solvent and under the action of an oxidizer so as to obtain 5-carbonyl-2-phenyl -1, 3-dioxane having a structure as shown in the formula (II); and (3) hydrolysis reaction, which is to hydrolyze the obtained 5-carbonyl-2-phenyl -1, 3-dioxane in the presence of an acid catalyst B so as to prepare a 1, 3-dihydroxyacetone dimer having a structure as shown in the formula (III). The synthetic route of the method uses the glycerin as a raw material, thus both the selectivity and the yield are higher than that by a method of direct oxidation, the target product is simple and convenient to separate, and the product purity can reach 99 percent; and compared with the prior art, the synthetic route of the method has stronger market competitiveness.

The invention discloses an enzyme for catalyzing formaldehyde to synthesize hydroxyl acetaldehyde and an application thereof. In the invention, through site-directed mutation of BFD, a mutant of the enzyme is found; and by means of the mutant of the enzyme, high-effect polymerization of the formaldehyde is achieved; meanwhile, through F / XPK, generation of acetyl phosphoric acid from the hydroxyl acetaldehyde or 1,3-dihydroxyacetone is achieved; with combination of phosphotransacetylase (Pta), a route from the formaldehyde to acetyl coenzyme A is achieved in three steps with the enzyme, thereby creating a new formaldehyde assimilation route, namely, synthesizing the acetyl coenzyme A from the formaldehyde in three steps. The route is short and is free of carbon loss and ATP input.

Certain known and novel pyruvate derivatives are particularly active in restoring or preserving metabolic integrity in oxidatively competent cells that have been subjected to oxygen deprivation. These pyruvate-derived compounds include, but are not limited to oximes, amides, pyruvate analogues, modified pyruvate analogues, esters of pyruvate (e.g., polyol-pyruvate esters, pyruvate thioesters, glycerol-pyruvate esters and dihydroxyacetone-pyruvate esters). Such pyruvate derivatives (including single tautomers, single stereoisomers and mixtures of tautomers and / or stereoisomers, and the pharmaceutically acceptable salts thereof) are useful in the manufacture of pharmaceutical compositions for treating a number of conditions characterized by oxidative stress.

A cosmetic self-tanning composition which comprises dihydroxyacetone and a ginkgo extract and / or grapeseed oil and / or a lotus blossom extract. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way.

The invention discloses a recombinant plasmid for expressing vitreoscilla hemoglobin in a cell and a construction method of the recombinant plasmid, a genetic engineering bacterium of Gluconobacter oxydans (G.oxydans) and a construction method and application of the genetic engineering bacterium. The recombinant plasmid comprises a vitreoscilla hemoglobin gene vgb, a PtufB promoter of the Gluconobacter oxydans (G.oxydans) and a suitable carrier, wherein the genetic engineering bacterium is obtained by transforming recombinant plasmid into a host bacterium. The genetic engineering bacterium can be used for expressing the vitreoscilla hemoglobin in the cell, can be used for improving the yield of biomass and catalysate 1, 3-dihydroxyacetone under the condition of not changing the existing equipment and energy consumption pressure and provides an effective path for solving the problem of in sufficient oxygen supply in the cell cultivation and catalytic process of the Gluconobacter oxydans (G.oxydans).

The invention discloses a strain in the field of genetic engineering and a method for producing dihydroxyacetone (DHA) by using the strain. The method is characterized in that: modified Gluconobacter oxydans is used to bioconvert glycerin into dihydroxyacetone; sldAB gene expression is added in the modified Gluconobacter oxydans through modification, and mgdh gene and madh gene are removed from the modified Gluconobacter oxydans; and the modified Gluconobacter oxydans is further subject to the adaptive evolution on a medium which uses glucose as the sole carbon source. The genetically engineered strain disclosed herein can grow well on the medium which uses glucose as the sole carbon source, overcomes the defects that wild type Gluconobacter oxydans can only use relatively expensive sorbitol and mannitol as the effective carbon source, and saves the production cost. In addition, compared with a genetically engineered strain GAN cultured on sorbitol, the genetically engineered strain GAN cultured on glucose has higher capability of producing DHA.

The invention discloses a method for synthesis of D-psicose by microbiological fermentation, specifically a method for synthesis of D-psicose by aldolase whole cell. The method includes: firstly constructing recombinant corynebacterium glutamicum SY12 carrying L-fucose-1-phosphate aldolase gene and fructose-1-phosphorylase gene (i.e. with aldehyde condensation approach), then adding glucose and D-glyceraldehyde into a basic salt medium, synthesizing dihydroxyacetone phosphate from glucose by means of intracellular glycolysis, synthesizing a single product D-psicose from D-glyceraldehyde and dihydroxyacetone phosphate (DHAP) under the action of the L-fucose-1-phosphate aldolase and fructose-1-phosphorylase carried by the corynebacterium glutamicum recombinant strain SY12, with the conversion rate of D-glyceraldehyde being 53%. Therefore, compared with the existing method for in vitro synthesis of D-psicose by ketose3-epimerase, the biosynthesis method of D-psicose provided by the invention has the advantages of high conversion rate, single product, easy separation and the like, and lays certain foundation for mass production of D-psicose.

The invention relates to a strain HD924 for producing dihydroxyacetone by microbial fermentation. The strain HD924 is classified into Acetobacteraceae Gluconobacter Gluconobacterfrateurii, and its collection number in the common micro-organism center of the CCCCM is CGMCC No.5397. The invention also provides a method for producing dihydroxyacetone by using the strain to ferment glycerin. dihydroxyacetone can be remarkably accumulated under aerobic conditions with the maximum of 170g / L. By the adoption of the method provided by the invention, industrial production can be realized.

The invention provides a catalyst for 1,3-dihydroxyacetone prepared from glycerin and a preparation method thereof. The catalyst is prepared by the steps: introducing an auxiliary component M into a hydrotalcite slab to form M-Zn-Y ternary hydrotalcite M-ZnY-LDHs, and calcining to obtain MOx / ZnYOz; taking the composite oxide as a carrier, supporting an Au salt onto the carrier, drying and reducing, thereby obtaining the Au-MOx / ZnYOz. The active ingredient Au of the catalyst is small in granule size, highly dispersed and stable under the actions of highly dispersed transition metal oxide MOx, has high catalytic oxidation activity of the glycerin and maintains excellent recyclability. The catalyst is applied to a reaction for preparing dihydroxy acetone by virtue of selective glycerin oxidation, and has high dihydroxy acetone yield under non-alkali conditions.

The invention discloses a high performance modified polyurethane coating. The coating comprises isophorone diisocyanate, polytetramethylene ether glycol, alkynyl group-containing polyol, phenylboronic acid, trimethylol propane, N,N-dimethylbenzylamine, cerium hydroxide, acidified carbon nanotubes, organic modified montmorillonite, 2,3-dibromo tripropylborate, triethylamine, 3,3'-diamino-4,4'-dihydroxydiphenylsulphone, 1-sulfolane-3-ethoxycarbonyl-5-hydroxypyrazole, 1,4-bis(dimethylhydroxysily)benzene, a leveling agent, methylsilicone oil, a wetting agent, benzoic acid, propylene glycol, dihydroxyacetone, adipic dihydrazide, liquid styrene butadiene rubber, liquid nitrile butadiene rubber and water. The high performance modified polyurethane coating has the advantages of excellent flame retardation performance, high strength, good heat stability, strong adhesion to a substrate, and long service life.

The invention relates to a fast screening method for dihydroxyacetone high-yielding strain, which is characterized in that a waiting colony is inoculated in the culture medium of perforated distribution plate until a single colony is grown; the fehling reagent is added to test; if a brown-red halo spot is shown around the single colony, the single colony is a positive strain; the positive strain is fetched to be inoculate to the inclined culture medium, and cultivated at 28 to 37 DEG C in 1 to 2 days; the inclined strain of the positive strain is obtained; the inclined strain is inoculated in the fermentation medium, and the zymotic fluid is cultivated by oscillation; the content of DNA in the zymotic liquid is determined; the DNA content of the zymotic fluid obtained by fermentation is higher than the DNA content of the 2 g / L positive strain, which is dihydroxyacetone high-producing strain. The fast screening method for dihydroxyacetone high-yielding strain has the advantages of simple operation, visual and convenient judgment to result, fast and high-flux screening of microbial strain well producing dihydroxyacetone, significantly decreased amount of labor, and increased labor efficiency.

The invention belongs to NADH oxidase in the field of biotechnology and particularly provides water type NADH oxidase of reproducible coenzyme NAD+ and an encoding gene and application thereof. The oxidase is represented by an amino acid sequence shown as SEQ ID NO.1. By the adoption of the water type NADH oxidase, 1,3-dihydroxyacetone can be produced through in-vitro serial connection and glycerin conversion of the oxidase and glycerol dehydrogenase. Compared with a chemical method for preparing the 1,3-dihydroxyacetone, the method has the advantages of being moderate in reaction condition, friendly to environment, simple in operation, easy to amplify and the like.

The invention provides an enzyme with a function of catalyzing formaldehyde for synthesis of 1,3-dihydroxyacetone. The enzyme is selected from following polypeptides (a) to (c): (a) polypeptides with amino acid sequences shown as SEQ ID NO.1; (b) polypeptides derived from (a) by replacing, deleting or adding one or more amino acids to the amino acid sequences in (a), wherein the polypeptides has a function of catalyzing formaldehyde condensation for synthesis of 1,3-dihydroxyacetone; (c) polypeptides with amino acid sequences in 95% similarity with those in (a), wherein the polypeptides has the function of catalyzing formaldehyde condensation for synthesis of 1,3-dihydroxyacetone. By the enzyme with the function of catalyzing formaldehyde for synthesis of 1,3-dihydroxyacetone, a novel method for synthesis of 1,3-dihydroxyacetone is established.

The invention discloses high fire resistant waterborne polyurethane wood varnish, which is prepared from the following raw material components in parts by weight: 100 parts of waterborne polyurethane emulsion, 3 to 6 parts of N-methyl pyrrolidone, 5 to 12 parts of ethylene glycol butyl ether, 25 to 35 parts of deionized water, 1 to 5 parts of nano-silver, 2 to 5 parts of bamboo charcoal powder, 0.1 to 0.5 part of defoamer, 0.1 to 0.5 part of wetting agent, 0.5 to 2 parts of thickener, 5 to 13 parts of modified antimonous oxide, 2 to 5 parts of dipropyl aluminum hypophosphite, 1 to 5 parts of aluminum polyacrylate, 1 to 2.5 parts of 1,3-dihydroxyacetone and 2 to 5 parts of adipic acid dihydrazide. The high fire retardant waterborne polyurethane wood varnish provided by the invention is good in fire retardancy, strong in adhesive force, has excellent antibacterial property and can meet the operating requirement of the wood varnish.

The present invention relates to the use of hydrocarbons derived from natural gas in the fermentative production of biochemicals including biofuels. More specifically, the present invention provides the method for manufacturing dihydroxyacetone (“DHA”) from natural gas, biogas, biomass and CO2 released from industrial plants including electricity-generating plants, steel mills and cement factories and the use of DHA as a source of organic carbon in the fermentative production of biochemicals including biofuels. The present invention comprises three stages. In the first stage of the present invention, syngas and formaldehyde are produced from natural gas, biogas, biomass and CO2 released from industrial plants. In the second stage of the present invention, formaldehyde and syngas are condensed to produce DHA. In the third stage of the present invention, biochemicals including biofuels are produced from DHA using fermentation process involving wild type or genetically modified microbial biocatalysts.

The invention relates to the technical field of organic synthesis, and discloses a preparation method of 1, 3-dihydroxyacetone. The preparation method of 1,3-dihydroxyacetone comprises the following steps: (1) carrying out contact reaction between glycerol and halogenated reagents in presence of a catalyst to prepare 1,3-dichloro-2-propanol; (2) carrying out oxidative dehydrogenation reaction on the 1,3-dichloro-2-propanol to obtain an intermediate product 1,3-dichloro-2 acetone; (3) contacting the 1,3-dichloro-2 acetone with alkali substances in a water-containing medium for hydrolysis reaction to obtain the 1,3-dihydroxyacetone, wherein a hydrolysis reaction temperature is 25 to 60 DEG C. According to the preparation method of the 1,3-dihydroxyacetone, the conversion rate of the glycerol and the yield of the 1,3-dihydroxyacetone are higher; by taking zirconium oxide as the catalyst, the preparation method disclosed by the invention is high-efficient, is low in cost and has industrial application prospect.

The invention discloses recombinant bacteria for producing gamma-aminobutyric acid by glycerin and a construction method of the recombinant bacteria. Firstly, a glycerin promoting protein gene glpF, a glycerin dehydrogenase gene dhaD and a dihydroxyacetone kinase gene dhaK are subjected to RBS random mutation to obtain corynebacterium glutamicum mutant strains capable of utilizing glycerin efficiently. Base strains capable of producing gamma-aminobutyric acid by glycerin are obtained through glutamate decarboxylase gene gad in over-expression bacillus megaterium. Glutamate decarboxylase is expressed by using RBS with different strength, and high-strength RBS is most favorable for synthesis of gamma-aminobutyric acid; then, the translocator gene gadC of the gamma-aminobutyric acid is over-expressed by increasing the level of precursor L-glutamic acid and knocking out the degradation way of the gamma-aminobutyric acid. Finally, 60 g / L of glycerin is used as a substrate, and the content of the gamma-aminobutyric acid reaches 10.94 g / L after fermentation for 84 h.

The invention discloses a preparation technique of 1,3-dihydroxyacetone. The technique specifically comprises the steps as follows: adding a glycerin aqueous solution and a catalyst into a high-pressure reaction kettle, sealing the reaction kettle completely, evacuating air three times with high-purity oxygen at room temperature, then filling the reaction kettle with 1.0MPa high-purity oxygen, stirring and heating to 70-90 DEG C, reacting at a constant temperature for 2-5h, cooling to room temperature with an ice bath, centrifuging, filtering and separating a reaction solution to obtain 1,3-dihydroxyacetone, wherein the catalyst comprises a carrier and active components, the carrier is a ZnAl-HTLc / carbon composite carrier, and the active components comprise Au, Bi and Ce. The catalyst prepared in the invention has very good glycerin conversion rate and selectivity on 1,3-dihydroxyacetone, thereby having broad application prospects.

The invention discloses a bifunctional catalyst for photocatalytic synthesis of dihydroxyacetone and hydrogen, a preparation method and application thereof, wherein the catalyst is oxygen-doped graphite-like carbon nitride, the oxygen-doped source is at least one of ammonium acetate, ammonium formate and ammonium oxalate, the carbon nitride precursor is at least one of urea, cyanamide, dicyandiamide, melamine and thiourea, and a mass ratio of the oxygen-doped source to the carbon nitride precursor is (1-10):100. Compared with the prior art, the bifunctional catalyst of the invention has the following advantages: (1) the bifunctional catalyst has good selectivity; (2) the reaction conditions of the bifunctional catalyst are mild, and an environmentally-friendly route is provided for high-added-value utilization of glycerol; and (3) the preparation method of the bifunctional catalyst is simple and efficient.

The invention relates to a catalyst for preparing dihydroxyacetone through oxidation of glycerol and a preparation method and application of the catalyst, and belongs to the technical field of chemical catalysis. The catalyst is a catalyst for preparing the dihydroxyacetone through oxidation of the glycerol, wherein the catalyst is an Au-based catalyst, a carrier of the catalyst is a copper zirconium composite oxide, and the molar ratio of cuprum to zirconium in the carrier of the catalyst is (1:100) to (100:1). The invention further accordingly provides the preparation method of the catalyst,and application of the catalyst in preparation of dihydroxyacetone through oxidation of the glycerol. According to the prepared supported Au catalyst, the dihydroxyacetone (DHA) can be prepared through high-efficiency catalytic oxidation of the glycerol in a heterogeneous alkali medium, the conversion rate of the glycerol can reach 80%, and the selectivity of the DHA can reach 95% or above. The reaction process conditions are mild, equipment corrosion is small, environmental protection is achieved, the present industrialization amplification requirements are achieved, and the catalyst has broad application prospects.

Methods of converting cellulose or related biorenewable carbohydrate materials into high-value chemical compounds. The methods provide a means of converting low-cost materials such as cellulose and biomass into high yields of compounds such as ethylene glycol, propylene glycol, glycerin, methanol, hydroxyacetone, glycolaldehyde and dihydroxyacetone.

The invention relates to a new method for producing dihydroxyacetone by converting glycerin by virtue of a biological fermentation process. The new method mainly comprises the following steps: producing dihydroxyacetone by fermenting a clavispora lusitaniae strain G10 with high glycerin resistance with two-order reactors and extracting dihydroxyacetone from the fermentation liquor. When the concentration of the glycerin substrate is 400g / L, the glycerin conversion rate is more than 85% and the yield is more than 75% after continuous fermentation is performed for 420 hours, so that the inhibiting effects of too high concentrations of the glycerin substrate of dihydroxyacetone prepared by existing microbiological fermentation methods and the product on the fermentation yield are effectively solved. The method adopted by the invention is simple to operate, is low in separation and extraction costs, is short in production time and is suitable for industrial production.

Bronzer compositions are provided. They comprise (a) water, (b) at least one water-soluble dye; and (c) at least one water-dispersible or water-soluble film-forming polymer. Optionally, a self-tanning agent such as 1,3-dihydroxyacetone may be present.