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3507 results about "Adipic acid" patented technology

Adipic acid or hexanedioic acid is the organic compound with the formula (CH₂)₄(COOH)₂. From an industrial perspective, it is the most important dicarboxylic acid: about 2.5 billion kilograms of this white crystalline powder are produced annually, mainly as a precursor for the production of nylon. Adipic acid otherwise rarely occurs in nature, but it is known as manufactured E number food additive E355.

Rapid acting and long acting insulin combination formulations

A combined rapid acting-long acting insulin formulation has been developed wherein the pH of the rapid acting insulin is adjusted so that the long acting glargine remains soluble when they are mixed together. In the preferred embodiment, this injectable basal bolus insulin is administered before breakfast, provides adequate bolus insulin levels to cover the meal, does not produce hypoglycemia after the meal and provides adequate basal insulin for 24 hours. Lunch and dinner can be covered by two bolus injections of a fast acting, or a rapid acting or a very rapid acting insulin. As a result, a patient using intensive insulin therapy should only inject three, rather than four, times a day. Experiments have been performed to demonstrate, the importance of the addition of specific acids to hexameric insulin to enhance speed and amount of absorption and preserve bioactivity following dissociation into the monomeric form by addition of a chelator such as EDTA. As shown by the examples, the preferred acids are aspartic, maleic, succinic, glutamic and citric acid. These are added in addition to a chelator, preferably ethylenediaminetetraacetic acid (EDTA). The results show that the citric acid formulation was more effective at dropping the blood glucose rapidly than the identical rapid acting formulation prepared with HCl in swine. Charge masking by the polyacid appears to be responsible for rapid insulin absorption. EDTA was not effective when used with adipic acid, oxalic acid or HCl at hastening the absorption of insulin. These results confirm the results seen in clinical subjects and patients with diabetes treated with the rapid acting insulin in combination with citric acid and EDTA.
Owner:ELI LILLY & CO

Use of eco-friendly microemulsions in oil cleaning applications

An environmentally-friendly cleaning composition for oil cleaning comprising (a) a blend of dibasic esters, (b) one or more surfactants (c) and, optionally, (d) water or a solvent. The dibasic esters are be derived from a blend of adipic, glutaric, and succinic diacids, and, in one particular embodiment, the blend comprises dialkyl adipate, dialkyl methylglutarate and dialkyl ethylsuccinate, wherein the alkyl groups individually comprise a C1-C12 hydrocarbon group. The one or more surfactants are typically chosen from alcohol alkoxylate, an alkyl phenol ethoxylate, a terpene, a terpene alkoxylate or any derivates thereof. Optionally, additional components or additives including delaminates such as pinene and d-limonene, fragrances, whiteners, stabilizers, thickeners and the like can be added to the composition.
Owner:RHODIA OPERATIONS SAS

Plasticizer Blends and Use Thereof

Provided are mixtures of 1) compounds of the formula:wherein R1 is a saturated or unsaturated cyclic hydrocarbon optionally substituted with an alkyl and / or an OXO-ester, and R2 is a C4 to C14 hydrocarbyl; and 2) one or more second plasticizers selected from the group consisting of alkyl terephthalates, alkyl phthalates, alkyl benzoate esters, di-benzoate esters, esters of cyclohexane polycarboxylic acids, and dialkyl adipates. Also provided are plasticized polymer compositions containing said mixtures.
Owner:EXXONMOBIL CHEM PAT INC

Process and equipment for preparing adipic acid by catalyzing air and oxidizing cyclohexane

The invention discloses a process and a plant for preparing adipic acid by catalytically aerobically oxidizing cyclohexane. The process comprises the following steps: dissolving 1 to 50 PPM of a catalyst including single metalloporphyrin or mu-oxo bimetallic porphyrin or a mixture of single metalloporphyrin, mu-oxo bimetallic porphyrin and transition metal salt or oxide in cyclohexane; introducing 5 to 12 atm of air or oxygen-rich or oxygen-poor air into a multi-stage oxidation reactor with a gas distributor; controlling the reaction temperature at 140 to 160 DEG C; oxidizing cyclohexane for 45 to 120 min; feeding the mixture of the oxidation reaction into a flash separator to carry out flash evaporation at the temperature of 78 to 155 DEG C and under the pressure of 0.1 to 1.0 atm, so that the low-boiling-point products such as cyclohexane, cyclohexanol and cyclohexanone change to gas and are separated from adipic acid with the content above 80%; continuously circularly oxidizing the low-boiling-point products to separate and purify the high-boiling-point oxidation product; and purifying and separating by the existing technique to obtain fine adipic acid product. The process can directly prepare adipic acid by aerobically oxidizing cyclohexane, wherein the conversion rate of cyclohexane is up to 95%, and the yield of adipic acid is up to 70%.
Owner:HUNAN UNIV

Thermoplastic polyurethane elastomer and manufacturing method thereof

InactiveCN101735596AExtrusion stabilityExtrusion less crystal pointChemistryAntioxidant
The invention relates to the manufacturing field of a special extrusion grade T-die thermoplastic elastomer, in particular to a manufacturing formula and a manufacturing method thereof. The formula comprises the following components: 20-40% of 4,4'-diphenylmethane-diisocyanate, 15-70% of polybutylene adipate the molecular weight of which is 1000 or 2000, 0-50% of poly butylene glycol adipate the molecular weight of which is 2000, 5-15% of 1,4-butanediol, 0-5% of glycol, 0.1-1.0% of antioxidant, 0.1-1.0% of lubricant, 0.001-0.1% of environment-friendly catalyst, 0.1-1.0% of ultraviolet absorbent, 0.1-1.0% of light stabilizer and 0.1-1.0% of hydrolysis resistant agent. Continuous production processes are used for synthesizing TPU (thermoplastic polyurethane). The product of the invention has the advantages of stable quality, excellent performance, few T-die extrusion crystal points, good transparency (more than 4mm), stable extrusion, no occurrence of separation of additives, high hydrolysis resistance and high UV (ultraviolet) resistance, and the indexes and the performance of the product can reach the indexes of international like products. The invention provides a thermoplastic polyurethane elastomer and a manufacturing method thereof.
Owner:SHANGHAI LIANJING MATERIAL ASSETAB

Rapid Acting and Long Acting Insulin Combination Formulations

A combined rapid acting-long acting insulin formulation has been developed wherein the pH of the rapid acting insulin is decreased so that the long acting glargine remains soluble when they are mixed together. In the preferred embodiment, this injectable basal bolus insulin is administered before breakfast, provides adequate bolus insulin levels to cover the meal, does not produce hypoglycemia after the meal and provides adequate basal insulin for 24 hours. Lunch and dinner can be covered by two bolus injections of a fast acting, or a rapid acting or a very rapid acting insulin. As a result, a patient using intensive insulin therapy should only inject three, rather than four, times a day. Experiments have been performed to demonstrate the importance of the addition of specific acids to hexameric insulin to enhance speed and amount of absorption and preserve bioactivity following dissociation into the monomeric form by addition of a chelator such as EDTA. As shown by the examples, the preferred acids are aspartic, glutamic and citric acid. These are added in addition to a chelator, preferably ethylenediaminetetraacetic acid (EDTA). The results show that the citric acid formulation was more effective at dropping the blood glucose rapidly than the identical rapid acting formulation prepared with HCl in swine. Charge masking by the polyacid appears to be responsible for rapid insulin absorption. EDTA was not effective when used with adipic acid, oxalic acid or HCl at hastening the absorption of insulin. These results confirm the results seen in clinical subjects and patients with diabetes treated with the rapid acting insulin in combination with citric acid and EDTA.
Owner:ELI LILLY & CO

Polyester plasticizer and chlorine-containing resin compositions

ActiveUS20060025544A1Superior in plasticization efficiencyGood oil resistancePlastic/resin/waxes insulatorsLavatory sanitoryPolyesterAdipic acid
A polyester plasticizer which is obtained by reacting a diol component (a) consisting of 100 parts by mole of 2-methyl-1,3-propanediol, 10 to 1000 parts by mole of 3-methyl-1,5-pentanediol and 0 to 1000 parts by mole of other aliphatic diol with an organic dicarboxylic acid components (b) consisting of 100 parts by mole of adipic acid and 0 to 100 parts by mole of other organic dicarboxylic acid and a chain terminator (c) consisting of a monovalent aliphatic alcohol or a monovalent aliphatic organic acid and which has an average molecular weight of 500 to 5000. This plasticizer is excellent in plasticizing efficiency and can impart excellent oil resistance to synthetic resins such as chlorine-containing resins.
Owner:ADEKA CORP

Biodegradable polymeric nanocomposite compositions particularly for packaging

Specific polymer blends of polylactic acid (PLA) and polyhydroxybutyrate (PHB) and poly-(butylenes adipate-co-terephthalate (PBAT) as a fatty acid quaternary ammonium modified clay. The blends are particularly useful for barrier packaging.
Owner:BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIV

Scaling powder for no-clean lead-free low-silver welding paste

The invention discloses scaling powder for no-clean lead-free low-silver welding paste. The scaling powder comprises, by weight percentage, 3-13% of active agent, 0.2-1.5% of surface active agent, 0.2-3.0% of emulgator, 3.0-10.0% of thixotropic agent, 3-8% of film-forming agent, 0.1-1% of antioxidant, 0.1-0.5% of corrosion inhibitor and the rest of solvent. The active agent is composed of four or five components in succinic acid, oxalic acid, salicylic acid, glutaric acid, citric acid, adipic acid, lactic acid, benzoic acid, malic acid and triethanolamine. The scaling powder for the no-clean lead-free low silver welding paste does not contain halogen, the corrosion to a circuit board is greatly lowered, the printing quality of the welding paste is good without bridging or turned-down edges, a welding point is good in forming after returning, the brazing connecting defect is greatly lowered, the residue is small without solder balls, the cleaning is not needed, the welding paste is directly used for assembling, the Sn-0.45 Ag-0.68 Cu or Sn-0.3 Ag-0.7 Cu low silver welding paste manufactured by using the scaling powder does not contain the halogen and rosin, the organic chemistry smoke is small, and the pollution to the environment is small.
Owner:CHONGQING UNIV OF TECH

Aqueous dispersion for chemical mechanical polishing

There is provided an aqueous dispersion for CMP with an excellent balance between chemical etching and mechanical polishing performance. The aqueous dispersion for CMP of the invention is characterized by comprising an abrasive, water and a heteropolyacid. Another aqueous dispersion for CMP according to the invention is characterized by comprising an abrasive, water, a heteropolyacid and an organic acid. Yet another aqueous dispersion for CMP according to the invention is characterized by comprising colloidal silica with a primary particle size of 5-100 nm, water and a heteropolyacid. Preferred for the heteropolyacid is at least one type selected from among silicomolybdic acid, phosphorotungstic acid, silicotungstic acid, phosphoromolybdic acid and silicotungstomolybdic acid. Preferred for the organic acid is at least one selected from among oxalic acid, malonic acid, succinic acid, glutaric acid, adipic acid, maleic acid, fumaric acid, phthalic acid, malic acid, tartaric acid and citric acid.
Owner:JSR CORPORATIOON
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