The invention relates to a Chinese patent medicine for treating leucoderma. The Chinese patent medicine consists of eclipta alba, tuber fleeceflower root, Chinese angelica, szechuan lovage rhizome, astragalus, largehead atractylodes rhizome, tuckahoe, glossy privet fruit, black sesame, suberect spatholobus stem, divaricate saposhnikovia root, fineleaf schizonepeta herb, red paeony root, flowery knotweed stem, knotweed, saffron, tribulus fruit, black soybean hull, malaytea scurfpea fruit and liquoric root, wherein various formulations for oral administration are prepared from the Chinese medicines according to the conventional preparation method. Compared with the prior art, the Chinese patent medicine has the effects of warming and invigorating liver and kidney, dispelling wind and removing rheumatism, regulating qi and blood, clearing and activating channels and collaterals, promoting blood circulation and removing blood stasis, regulating an immunologic function and improving skin microcirculation, and has the outstanding substantial characteristics and obvious improvement of definite curative effects on the treatment and prevention of leucoderma, convenience for administration and the like.