The invention provides a skin barrier repairing compound, a pre-essence and a preparation method of the pre-essence. The
skin barrier repairing compound is prepared from a
skin barrier repairing composition, madecassoside, a grape leaf extract, a
chondrus crispus extract, glycosphingolipids and glycolipids, the
skin barrier repairing composition is prepared from crithmum maritimum
callus culture filtrate, tetrahydromethyl pyrimidinecarboxylic acid and a hydrolyzed red alga extract; and the pre-essence comprises the following components in percentage by
mass: 1-10% of the
skin barrier repairingcompound, 10-30% of a
humectant, 1-10% of an emollient, 1-5% of an emulsifier and the balance of water. The
skin barrier repairing compound can effectively balance a microbial barrier, stabilize a keratinous barrier and strengthen an
immunity barrier, so that the skin is healthy and stable. The pre-essence prepared from the skin barrier repairing compound can effectively regulate
cutin renewal, strengthen the skin
cutin barrier and improve the skin resistance.