Essence containing ultra-small molecular sodium hyaluronate and preparation method thereof
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Embodiment 1
[0037] prescription:
[0038] The essence prescription of table 1 embodiment 1
[0039]
[0040]
[0041] The preparation process of the above-mentioned ultra-small molecular sodium hyaluronate essence is as follows: heat the deionized purified water to 60°C and keep it warm; add 1,3-butanediol, 1,2-pentanediol, 1,2-hexane Diol, methyl gluceth polyether, macromolecular sodium hyaluronate, hydrolyzed sodium hyaluronate and ultra-small molecular sodium hyaluronate, stir and mix to disperse evenly to obtain a mixed solution; mix the above mixed solution with deionized The purified water is stirred and dissolved, then cooled to room temperature, sent for inspection, and discharged after passing the test to obtain a colorless and transparent essence.
Embodiment 2
[0043] prescription:
[0044] The essence prescription of table 2 embodiment 2
[0045] # Element Prescription volume (g or ml) weight percentage 1 Ultra-small molecule sodium hyaluronate (1kDa) 1g 1% 2 Hydrolyzed Sodium Hyaluronate (50kDa) 0.5g 0.5% 3 Macromolecular Sodium Hyaluronate (1000kDa) 0.5g 0.5% 4 Humectant: Methyl Gluceth 3g 3% 5 Humectant: 1,3-Butanediol 6g 6% 6 Antibacterial agent: 1,2-pentanediol 2g 2% 7 Antibacterial agent: 1,2-Hexanediol 0.5g 0.5% 8 purified water Add to 100ml add up to 100%
[0046] The preparation process of the above-mentioned ultra-small molecular sodium hyaluronate essence is as follows: heat the deionized purified water to 80°C and keep it warm; add 1,3-butanediol, 1,2-pentanediol, 1,2-hexane Diol, methyl gluceth polyether, macromolecular sodium hyaluronate, hydrolyzed sodium hyaluronate and ultra-small molecular sodium hyaluronate, stir and mix to disper...
Embodiment 3
[0048] prescription:
[0049] The essence prescription of table 3 embodiment 3
[0050] # Element Prescription volume (g or ml) weight percentage 1 Ultra-small molecule sodium hyaluronate (2kDa) 0.5g 0.5% 2 Hydrolyzed Sodium Hyaluronate (30kDa) 0.5g 0.5% 3 Macromolecular Sodium Hyaluronate (3000kDa) 0.3g 0.3% 4 Humectant: Methyl Gluceth 3g 3% 5 Humectant: 1,3-Butanediol 5g 5% 6 Antibacterial agent: 1,2-pentanediol 2g 2% 7 Antibacterial agent: 1,2-Hexanediol 0.8g 0.8% 8 purified water Add to 100mL add up to 100%
[0051]The preparation process of the above-mentioned ultra-small molecular sodium hyaluronate essence is as follows: heat the deionized purified water to 50°C and keep it warm; add 1,3-butanediol, 1,2-pentanediol, 1,2-hexane Diol, methyl gluceth polyether, macromolecular sodium hyaluronate, hydrolyzed sodium hyaluronate and ultra-small molecular sodium hyaluronate, stir and mix to dis...
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