579 results about "Skin wrinkle" patented technology

I have discovered cosmetic or topical pharmaceutical compositions for external body part or organ slimming, firming, cellulite reduction, fat-reduction, and obesity control benefits that are in synergistic combination with benefits for the treatment of skin aging, skin wrinkles reduction, skin exfoliating, treatment of acne, treatment of rosacea, age-spots reduction, skin surface whitening, skin surface brightening striae distensae (stretch marks) reduction, treatment of pimples, treatment of skin infections and lesions, spider veins reduction, blood microcirculation (venous insufficiency) improvement, UVA / UVB protection of skin, and skin redness reduction. These compositions thus provide multiple combinations of skin and external body part or organ enhancement benefits that can be selective and specific for external body parts and organs such as face, chin, cheeks, arms, "love handles" in abdomen area, eye lids and eye zone, neck, breasts, thighs, and hips. These compositions include a body beneficial composition selected from certain nutraceutical, cosmetic, and pharmaceutical ingredients, a composition to promote collagen and elastin synthesis in the skin, and a cosmetically or pharmaceutically acceptable delivery system.

The invention encompasses the treatment of urinary incontinence, gastroesophageal reflux disease and the amelioration of skin wrinkles using biocompatible hydrophilic cationic microparticles and a cell adhesion promoter.

This invention relates to certain sugar esters of phytosterols of formula (I). These esters are useful for topical application, and for the treatment of skin condition, including age spots, acne, loss of cellular antioxidants, collagen loss, loss of skin pliability, loss of skin suppleness, skin wrinkles including fine lines, oxidation, damage from radiation, malfunction of matrix metalloproteases, malfunction of tyrosinases, damage from free radicals, damage from UV, dry skin, xerosis, ichthyosis, dandruff, brownish spots, keratoses, melasma, lentigines, liver spots, pigmented spots, dark circles under the eyes, skin pigmentation including darkened skin, blemishes, oily skin, warts, eczema, pruritic skin, psoriasis, inflammatory dermatoses, topical inflammation, disturbed keratinization, skin changes associated with aging, nail or skin requiring cleansers, conditioning or treatment, and hair or scalp requiring shampooing or conditioning, and combinations thereof;Wherein,n=0, 1, 2, or 3; andR=H, —CH2OH, —CH(OH)—CH2OH, —CH(OH)—CH(OH)—CH2OH; andR1=Substituent selected from a sapogenin, steroid, or terpenoid.

The invention discloses a cosmetic anti-aging skincare composition containing nicotinamide mononucleotide (NMN). The NMN is taken as the active component and is used to produce the cosmetic anti-aging skincare composition. Because the NMN is the single substance in organism cells, the safety of the NMN is high. The provided skincare composition can prevent skin becoming rough and aged, reduce the skin wrinkles, and maintain the elasticity and bright color of the skin.

The invention belongs to the technical field of cosmetics and particularly relates to anti-wrinkle essence and a preparing method thereof. The anti-wrinkle essence is prepared from cyclomethicone, butanediol, polydimethylsiloxane, poly(sodium L-glutamate), glycerinum, propylene glycol, polyglycerol-10, dipropylene glycol, erythritol, hydroxyethyl acrylate / acryloyl 2 methyl taurine sodium copolymer, bio-saccharide gum, xylitol, C20-22 alcohol phosphate / C20-22 alcohol, lactic acid bacillus / pomegranate fruit extracts of fermented products, arctic rock chlamydomonas essence, starfish essence, hexapeptide-3, orange flower essence, gentian root extracts, arbutin, milk protein, tranexamic acid and the like. The anti-wrinkle essence is good in permeability and easy to absorb, effective moisturizing is achieved, skin wrinkles are repaired and inhibited from being regenerated, and skin aging is delayed.

The embodiment described herein are related nanoemulsions comprising botulinum toxins. In one embodiment, the nanoemulsions are prepared by high pressure microfluidization and comprise a particle size distribution exclusively between 10 and 300 nm. The nanoemulsions contemplated by the present invention are useful for the cosmetic and medical treatment of muscular contracture states. For example, botulinum toxin may relax facial muscles such that skin wrinkles become smoother and less noticeable. Further, the present invention contemplates a cosmetic formulation that may be self-administered, for example, in the privacy of one's home and without medical supervision.

Compositions containing nicotinamide riboside (NR) are provided. NR containing compositions are used in the care or treatment of skin and skin conditions. In some embodiments, the invention relates to pharmaceutical compositions and cosmetic compositions containing nicotinamide riboside. In further embodiments, the invention relates to methods of using nicotinamide riboside to promote the increase of intracellular levels of nicotinamide adenine dinucleotide (NAD+) in cells and tissues for improving cell and tissue survival. A method of treating signs or symptoms of aging or skin wrinkles in an individual is provided, comprising topically administering to the individual in need of such treatment an effective amount of the compound nicotinamide riboside, or salts thereof.

A method for treating skin may first involve contacting an applicator of a skin heating device with an epidermal layer of the skin. The applicator may be activated to generate high-frequency alternating magnetic fields. The applicator may be used to heat a dermal layer of the skin, with the high-frequency alternating magnetic fields, to a temperature of less than 40 degrees Celsius, to stimulate a release of heat shock protein in the dermal layer to promote collagen generation. The method may also involve limiting heating of the dermal layer of the skin to less than 40 degrees Celsius.

The embodiment described herein are related nanoemulsions comprising botulinum toxins. In one embodiment, the nanoemulsions are prepared by high pressure microfluidization and comprise a particle size distribution exclusively between 10 and 300 nm. The nanoemulsions contemplated by the present invention are useful for the cosmetic and medical treatment of muscular contracture states. For example, botulinum toxin may relax facial muscles such that skin wrinkles become smoother and less noticeable. Further, the present invention contemplates a cosmetic formulation that may be self-administered, for example, in the privacy of one's home and without medical supervision.

This invention relates to the use of a composition comprising a polysaccharide and a botulinum toxin for reducing a skin wrinkle. In some embodiments, the polysaccharide comprises disaccharides. In some embodiments, the average molecular weight of a disaccharide unit of the polysaccharide is between about 345 D and about 1,000 D.

The invention relates to a medical biological dressing, particularly to a medical biological scar-inhibiting rhytidectomy dressing and a preparation method thereof. The dressing is composed of modified chitosan, silicone, glycerol, camellia oil, olive oil, almond oil, an aloe extracting solution, active growth factors, hyaluronic acid and a ginger extracting solution. With adoption of the formula, skin regeneration organs are retained and activated furthest, and a good foundation is laid for wound repair. The formula is reasonable and scientific and has the efficacies of clearing away heat and toxic materials, removing slough and promoting growth of tissue regeneration, promoting blood circulation and removing blood stasis, and relieving swelling and pain on scars, has an impressive preliminary therapeutic effect on scars of skin epidermis bruise, trauma, traumatism, burning, scald, and post-operation wound, has the advantages of high efficacy, rapid pain relieving, low possibility of infection, simple preparation method, and good convenience in usage and popularization, and is used for burning, scald, trauma, bruise, traumatism, post-operation wound hemostasis, inflammation diminishing, pain relieving, wound infection prevention, scar inhibition, skin wrinkle and crack prevention, and wrinkle inhibition.

Personalized skin-specific topical formulations containing conditioned medium obtained from cultures of fibroblasts has been developed. Unlike other topical formulations, these formulations are specific for the recipient-skin type specific, and conditioned medium is obtained from a subject with desired skin characteristics. For example, since African American skin is known to wrinkle less and later than Caucasian skin, conditioned medium may be obtained from African American skin for application to pale skin. In another embodiment, the fibroblasts are obtained from young skin for administration to older skin. In still another embodiment, the fibroblasts are obtained from skin that does not suffer from acne or discoloration, for application to skin that is prone to acne or discoloration. Examples of skin donor selection criteria include delayed wrinkling, small pores, resistance to sunburn, resistance to acne, uniform coloration or lack of blotching or age spots and good moisture retention.

The embodiment described herein are related nanoemulsions comprising botulinum toxins. In one embodiment, the nanoemulsions are prepared by high pressure microfluidization and comprise a particle size distribution exclusively between 10 and 300 nm. The nanoemulsions contemplated by the present invention are useful for the cosmetic and medical treatment of muscular contracture states. For example, botulinum toxin may relax facial muscles such that skin wrinkles become smoother and less noticeable. Further, the present invention contemplates a cosmetic formulation that may be self-administered, for example, in the privacy of one's home and without medical supervision.

Methods, compounds, and topical formulations for reduction of skin sagging, creasing and / or wrinkling are disclosed. The methods comprise topically applying a composition comprising an α2 adrenergic receptor agonist. Amelioration of skin sagging, creasing and / or wrinkling begins within minutes after topical application of a disclosed composition. A single application can significantly reduce skin sagging, creasing and / or wrinkling for at least about 8 hours.

The invention provides essence with a skin anti-wrinkle effect. The essence with the anti-wrinkle effect is developed by taking clinopodium urticifolium, hibiscus sabdariffa, abelmoschus esculentus, fullerene and hyaluronic acid as the main functional components, aiming at the key factors influencing the generation of skin wrinkles, such as ultraviolet rays, free radicals, inflammation, MMPs and the like. The components have the synergistic interaction, and have the efficacies of preserving moisture, supplementing extracellular matrix, resisting ultraviolet rays, scavenging the free radical, resisting inflammation, inhibiting MMPs expression and the like, so as to increase the thickness of the extracellular matrix and achieve the effect of resisting wrinkles. With the adoption of the essence, the defects in the prior art are overcome, a preparation method is simple, and the essence is suitable for large-scale promotion, and has the anti-wrinkle effect after long-term use.

The invention discloses a method for preparing fermented product filtrate by fermenting rice with lactobacillus casei, and the application of the fermented product filtrate. The method comprises the steps of firstly, carrying out heat sterilization on a culture medium; then, inoculating the lactobacillus casei into the culture medium, fermenting, and filtering to obtain the fermented product filtrate; after that, adjusting the pH value of the fermented product filtrate, and sterilizing to obtain the fermented product filtrate. After being used in the compositions of cosmetics, the fermented product filtrate has a good function of promoting the permeation of other components, the skin wrinkles can be reduced, and the skin melanin is reduced; the fermented product filtrate is high in biological safety, thus being widely applied to various cosmetics.

The invention discloses a face pack and a preparation method thereof. The face pack includes following raw materials by weight: 93.0-84.5 parts of pure water; 5-10 parts of starch; 1.0-3.0 parts of soybean protein; 0.5-1.5 parts of xanthan gum; 0.5-1 part of flexibilizer; and 0.1-0.15 part of anticorrosive. The preparation method of the present invention includes steps of mixing the raw materials, stirring, heating, moulding in a die, adding into beauty treatment nutrient solution with edible bird's nest powder or silk fibroin powder, sealing and packaging. The face pack is prepared from food-grade raw materials, has no toxic and side effect to human, is easy to degrade, and is green and environment-friendly. Gummy shaping pad pasting produced by the method is soft, has good application performance to the skin, can absorb and release more nutrient composition, has good moisture retention performance, can make skin smooth and elastic, and can lighten skin wrinkle.

Disclosed herein are compositions and methods to treat skin with a peracid-based benefit agent. The peracid benefit agent can be used for a benefit such as the prevention or treatment of acne, skin whitening, skin bleaching, skin conditioning, reducing the appearance of skin wrinkles, skin rejuvenation, reducing dermal adhesions, and preventing, reducing or eliminating body odors or any combination thereof. The peracid may be enzymatically generated from a carboxylic acid ester substrate using an enzyme having perhydrolytic activity (perhydrolase) in the presence of a source of peroxygen. A fusion protein comprising the perhydrolase coupled to a skin-binding domain, either directly or through an optional linker, may be used to target the perhydrolytic activity to the skin surface.

The invention provides a composition with functions of treating dysmenorrhoea and beautifying. The composition contains Chinese angelica, pseudo-ginseng, safflower and rose. The composition has a function of treating dysmenorrhoea as well as a beautifying function of treating chloasma, senile plaque expelling and skin wrinkles. The composition is a medicine with a plurality of effects.

This invention relates to the use of a composition comprising a polysaccharide and a botulinum toxin for reducing a skin wrinkle. In some embodiments, the polysaccharide comprises disaccharides. In some embodiments, the average molecular weight of a disaccharide unit of the polysaccharide is between about 345 D and about 1,000 D.

The invention belongs to the technical field of cosmetics, and particularly relates to whitening anti-aging essence liquid and a preparation method thereof. The whitening anti-aging essence liquid is prepared from polyethylene glycol, polydimethylsiloxane, poly(sodium glutamate), glycerinum, hyaluronic acid, xylitol, C20-22 alcohol phosphate / C20-22 alcohol, ginkgo leaf extracts, ophiopogon root extracts, herba portulacae extracts, caulis spatholobi extracts, milk protein and the like. The whitening anti-aging essence liquid is good in permeability, easy to absorb and capable of effectively supplementing water, moisturizing and whitening, repairing the skin wrinkles, reducing the fine wrinkles and delaying skin aging.

The present invention relates to an oral composition for improving the beauty of the skin, which exhibits the effects of reducing skin wrinkles and inhibiting wrinkle formation. The composition contains a collagen peptide and at least one selected from the group consisting of elastin protein, hyaluronic acid and vitamin C. Particularly, the composition contains the collagen peptide, the elastin protein, hyaluronic acid and vitamin C at the optimum ratio, and when it is taken into the human body, it has no side effect, maximizes the biosynthesis of collagen in the skin dermal layer, shows excellent in vivo retention rate, and exhibits the effects of inhibiting skin wrinkle formation, maintaining or improving skin elasticity and moisturizing the skin. Thus, the composition will be useful as a health functional food for improving the beauty of the skin and preventing skin aging.

The present invention includes peptides, compositions as well as their use for the prevention or treatment of various age related or pathological conditions of skin or other tissues including skin wrinkles, wounds, different types of fibrosis and methods of reconstructing different tissues such as techniques used in regenerative medicine. The invention further includes peptide mimetics and methods of use including interfering with transcriptional complexes characteristic of fibroblasts of aged skin and stimulating synthesis of structural components of extracellular matrix.

The invention provides a method for preparing a human stem cell sourcing biobeauty raw material. The method includes the steps of obtaining protein suspension from a culture solution of human stem cells and human stem cell lysis, after hyperconcentration, preparing into human stem cell essence which is rich in cell growth components and has the efficacy of skin regeneration and repairing; performing further freeze drying, and preparing into freeze-dried powder capable of being stored in a -80 DEG C ultra low temperature refrigerator for a long time to serve as a biobeauty raw material for skin regeneration and repairing. The biobeauty raw material can be added to face cream, body lotion and toner to prepare regeneration and repairing face cream products, or added to facial masks to prepare regeneration and repairing facial mask products, or directly prepared into regeneration and repairing essence products, which is applicable to beauty of skin wrinkles, hyperpigmentation and scars.

The invention relates to a medical biological dressing, and in particular relates to a medical biological wrinkle-removing and speckle-inhibiting dressing and a preparation method thereof. The dressing comprises hyaluronic acid, olive oil, collagen, geranium essential oil, camellia oil, apricot kernel oil, active growth factors, pearl powder, vitamin A, vitamin C, vitamin E, amino acid, garlic oil and mint oil. By adopting the formula, skin regeneration organs are reserved and activated to the most extent; the skin condition is improved; cell regeneration is promoted; the yield of skin collagen is increased; therefore, skin whitening, speckle removing and wrinkle smoothing are promoted; a good foundation is laid for repairing wounds; and the medical biological wrinkle-removing and speckle-inhibiting dressing has the excellent effects in early treatment of skin wrinkle, striae gravidarum, crows feet, stain and scar.

The invention provides a two-component whitening long-acting Shuiguang injection for correcting skin wrinkles. The injection comprises two components, i.e. a component 1 and a component 2, wherein thecomponent 1 is a gel made of a crosslinked hyaluronate and a non-crosslinked hyaluronate, and the component 2 is a diluent containing amino acid and whitening active components. The injection provided by the invention can supplement adequate nutrients to the skin, also can supplement collagen to form needed amino acids or polypeptides, and is added with whitening components, thus catering to theneeds of most beauty seekers for fair, watery and tender skin.

The invention provides a plant skin care composition with the moisturizing and skin elasticity improving effects and a cosmetic. The composition comprises honeysuckle extract, arabian jasmine flower extract and apple peel extract, wherein the compound proportion of the honeysuckle extract, the arabian jasmine flower extract and the apple peel extract is converted into the dry weight of the honeysuckle, the arabian jasmine flower and the apple peel, and the weight ratio is 3-5:7-9:0.5-1.5. According to the composition, the components act jointly so that the good moisturizing and skin elasticity improving effects can be achieved. The plant skin care composition can be applied to skin care type and washing type cosmetics, and the product has the effects of relieving skin ageing and skin wrinkles.

Disclosed are a combination technique for aesthetic biological stuffing and micro-needles arrays, and application method thereof, relating to injection of hyaluronic acid, collagen, carnitine, growth hormone, and fibroblast growth factor with micro-needles arrays, is characterizd in that enjecting aesthetic stuffing such as aminopolysaccharide, collagen, carnitine, growth hormone, and fibroblast growth factor into a back lining film with definite quantity, back buckling a micro-needles array chip on biological stuffing, sealing the liner film and the micro-needles array with a shaper, covering needles surface with a protecting film, packing, and obtaining a finished product. The product is used for tissue stuffing and skin wrinkles removing of human faces and necks, mammary enlargement, and hand back skin plumping. The invention is provided with high biological security reliability, an excellent recovery effect, and can be used with simplicity.

The invention provides a method for preparing a biological beautifying facial mask containing adipose derived stem cells. The method comprises the following steps: culturing and acquiring adipose-derived stem cells from autogenous fat, and acquiring platelet enriched plasma from autogenous peripheral blood; adding agarose into normal saline, heating and dissolving, and adding the platelet enriched plasma when the liquid temperature is reduced to about 40 DEG C; uniformly mixing, and adding adipose derived stem cells to prepare the biological beautifying facial mask. Furthermore, nutritional factors can be added to prepare a personalized biological beautifying facial mask product. The facial mask can be used for removing skin wrinkles and acne marks, repairing scars, lightening spots, resisting oxidation and the like.