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426results about How to "Reduce appearance" patented technology

Single-primer nucleic acid amplification methods

The present invention is directed to novel methods of synthesizing multiple copies of a target nucleic acid sequence which are autocatalytic (i.e., able to cycle automatically without the need to modify reaction conditions such as temperature, pH, or ionic strength and using the product of one cycle in the next one). In particular, the present invention discloses a method of nucleic acid amplification which is robust and efficient, while reducing the appearance of side-products. The method uses only one primer, the “priming oligonucleotide,” a promoter oligonucleotide modified to prevent polymerase extension from its 3′-terminus and, optionally, a means for terminating a primer extension reaction, to amplify RNA or DNA molecules in vitro, while reducing or substantially eliminating the formation of side-products. The method of the present invention minimizes or substantially eliminates the emergence of side-products, thus providing a high level of specificity. Furthermore, the appearance of side-products can complicate the analysis of the amplification reaction by various molecular detection techniques. The present invention minimizes or substantially eliminates this problem, thus providing an enhanced level of sensitivity.
Owner:GEN PROBE INC

Single-primer nucleic acid amplification methods

The present invention is directed to novel methods of synthesizing multiple copies of a target nucleic acid sequence which are autocatalytic (i.e., able to cycle automatically without the need to modify reaction conditions such as temperature, pH, or ionic strength and using the product of one cycle in the next one). In particular, the present invention discloses a method of nucleic acid amplification which is robust and efficient, while reducing the appearance of side-products. The method uses only one primer, the “priming oligonucleotide,” a promoter oligonucleotide modified to prevent polymerase extension from its 3′-terminus and, optionally, a means for terminating a primer extension reaction, to amplify RNA or DNA molecules in vitro, while reducing or substantially eliminating the formation of side-products. The method of the present invention minimizes or substantially eliminates the emergence of side-products, thus providing a high level of specificity. Furthermore, the appearance of side-products can complicate the analysis of the amplification reaction by various molecular detection techniques. The present invention minimizes or substantially eliminates this problem, thus providing an enhanced level of sensitivity.
Owner:GEN PROBE INC

Topical administration of danazol

InactiveUS20080153789A1Diminished side effectReduce abundance and appearanceBiocideCosmetic preparationsEmulsionPharmaceutical preservatives
Pharmaceutical preparations for topical or local administration of drugs directly to the skin for treatment of disorders of the subcutaneous fatty tissue, in particular in cases of cellulite, are disclosed herein. In a preferred embodiment, the drug is danazol or gastrinone. In another embodiment, the drug is danazol in combination with an aromatase inhibitor or an estrogen compound. The preferred formulations contain drugs in the form of micro or nanoparticles, which may be formed of drug alone or in combination with an excipient or carrier. The excipient or carrier may modify the release rates or enhance absorption into the affected area. The drug formulation may be in the form of a cream, lotion, ointment, gel or emulsion, solution or foam.
Owner:FEMMEPHARMA HLDG CO INC

Detachable shock absorber accessory for shoulder strap

Portable objects such as luggage, cases, purses, bags, sporting equipment, weaponry and the like typically have a handle and a detachable shoulder strap. The discomfort caused by the weight of the object and the shock to both carrier and object of walking is alleviated by clipping an elastic apparatus between the ends of the shoulder strap and the portable object. Disclosed is a short elastic suspender that includes an elastic strap to be removably attached by a first connector to the D-ring of a portable object. The other end of the suspender has a D-ring connector configured to removably be attached to by the snap / hook fastener of the original shoulder-carrying strap of the portable object.
Owner:NOLAN BARARA K +1

Color adjusting arrangement

Disclosed is a color adjusting arrangement comprising: i) a first wavelength converting material arranged to receive ambient light and capable of converting ambient light of a first wavelength range into light of a second wavelength range, and/or reflecting ambient light of said second wavelength range, said second wavelength range being part of the visible light spectrum; and ii) a complementary wavelength converting material arranged to receive ambient light and capable of converting part of said ambient light into light of a complementary wavelength range, which is complementary to said second wavelength range, and arranged to allow mixing of light of said second wavelength range and said complementary wavelength range; such that light of said second wavelength range that is emitted and/or reflected by said first wavelength converting material and light of said complementary wavelength range is mixed when leaving the color adjusting arrangement towards a viewing position, the light leaving the color adjusting arrangement thereby appearing less colored, i.e. having a color point substantially near the black body line. The invention thus allows an undesirable colored appearance of a semiconductor-phosphor based light source to be at least partly extinguished or neutralized.
Owner:KONINKLIJKE PHILIPS ELECTRONICS NV

Methods of treating the skin

InactiveUS20060008538A1Reduce appearanceReducing of skinAntibacterial agentsBiocideSkin toneAcne
The invention features a method of (i) reducing the appearance of pores or oil on the skin and (ii) evening skin tone or smoothing skin by applying to an area of skin in need of such treatment a composition including an anti-acne agent, an antimicrobial agent, and a lactate.
Owner:JOHNSON & JOHNSON CONSUMER COPANIES

Carrier device for thermal transfer medium, discrimination method using the same, and printer

The invention provides a carrier device for a thermal transfer medium comprising a spool for winding and supporting a thermal transfer sheet or a thermal transfer receiving sheet, wherein a mark containing a coloring material which absorbs an electromagnetic wave of a predetermined wavelength λ1 and emitting an electromagnetic wave of a wavelength λ2 different from the wavelength λ1 is provided on a region in a surface of the carrier device capable of being irradiated with an electromagnetic wave. The invention provides a discrimination method and a printer each of which utilizes such a carrier device capable of executing at least one process among the kind identification, the fake goods determination and the use amount calculation for the thermal transfer sheet or the thermal transfer receiving sheet based on a detection of the mark.
Owner:DAI NIPPON PRINTING CO LTD
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