117results about How to "Preventing initiation" patented technology

A method and apparatus are disclosed for controlling optical aberrations to alter relative curvature of field by providing ocular apparatuses, systems and methods comprising a predetermined corrective factor to produce at least one substantially corrective stimulus for repositioning peripheral, off-axis, focal points relative to the central, on-axis or axial focal point while maintaining the positioning of the central, on-axis or axial focal point on the retina. The invention will be used to provide continuous, useful clear visual images while simultaneously retarding or abating the progression of myopia or hypermetropia.

A multi-channel apparatus for classifying particles according to one or more particle characteristics. The apparatus comprises a plurality of flow cytometry units, each of which is operable to classify particles in a mixture of particles by interrogating a stream of fluid containing the particles with a beam of electromagnetic radiation. The flow cytometry units share an integrated platform comprising at least one of the following: (1) a common supply of particles; (2) a common housing; (3) a common processor for controlling operation of the units; (4) a common processor for receiving and processing information from the units; and (5) a common fluid delivery system. The integrated platform can include a common source of electromagnetic radiation. A method of the invention comprises using a plurality of flow cytometry units sharing the integrated platform to perform a flow kilometric operation, such as analyzing or sorting particles.

A method and apparatus are disclosed for controlling optical aberrations to alter relative curvature of field by providing ocular apparatuses, systems and methods comprising a predetermined corrective factor to produce at least one substantially corrective stimulus for repositioning peripheral, off-axis, focal points relative to the central, on-axis or axial focal point while maintaining the positioning of the central, on-axis or axial focal point on the retina. The invention will be used to provide continuous, useful clear visual images while simultaneously retarding or abating the progression of myopia or hypermetropia.

A method, system and program for preventing intrusion in a communications network. A source node initiates a request for network services, such as session establishment, database access, or application access. Known network resources and authorized user information is stored in a database at a network portal along with access policy rules that are device and user dependent. Identification of the source node is required before the source node can construct a transformed packet header that is included with a synchronization packet before transmission to a destination node. An appliance or firewall in the communications network receives and authenticates the synchronization packet before releasing the packet to its, intended destination. The authentication process includes verification of the access policy associated with the source node. Once received at the destination node, the transformed packet header is reformed by extracting a key index value. The extracted key index is subsequently used to transform the packet header in the response transmitted to the source node.

The present invention provides compositions, kits and methods for the selective hybridization and capture of a specific target nucleic acid. The specific target nucleic acid may be present in a heterogeneous mixture of nucleic acids. Selective hybridization and capture provides a target nucleic acid that is substantially free of non-target and / or contaminating nucleic acids. Target nucleic acids that have been selectively hybridized and captured using the current invention are then used in subsequent analysis, wherein the presence of non-target and / or contaminating nucleic acids that interfere with said subsequent analysis have been substantially reduced or eliminated, thereby providing improved analysis results. The invention offers the further advantage of requiring less stringent purification and / or sterility efforts than conventionally needed in order to ensure that enzymes and other reagents used in subsequent analysis, or present in the environment in which an assay is performed, are free of bacterial or other contaminating nucleic acids.

A clustered computer system, apparatus, program product and method utilize a group member-initiated shutdown process to terminate clustering on a node in an automated and orderly fashion, typically in the event of a failure detected by a group member residing on that node. As a component of such a process, node leave operations are initiated on the other nodes in a clustered computer system, thereby permitting any dependency failovers to occur in an automated fashion. Moreover, other group members on a node to be shutdown are preemptively terminated prior to local detection of the failure within those other group members, so that termination of clustering on the node may be initiated to complete a shutdown operation.

An electric driving machine has a motor for rotating a flywheel, power transmission for converting rotational drive force of the flywheel into rectilinear drive force and transmitting the rectilinear drive force to an actuator which fires a fastener, and engagement / disengagement arrangement which transmits the rotational drive force of the flywheel to a driver blade of interrupts transmission of the rotational drive force. The electric driving machine is provided with a second switching element connected in series with the engagement / disengagement arrangement and a third switching element connected in shunt with the engagement / disengagement arrangement. When a push lever switch is in an OFF position where driving of a fastener is not ready, the third switching element is held in an ON state.

A method and system for monitoring UDP communications and for preventing unauthorized UDP communications within a computer network. A method for managing access to a resource comprises assigning a unique user identifier to each authorized user, upon initiation of a UDP communication initialed by a specific authorized user for access to a specific resource, appending the unique user identifier of the specific authorized user to each UDP packet of the UDP communication, intercepting the plurality of UDP packets within the computer network, extracting the unique user identifier from each UDP packet to identify the specific authorized user associated with the respective UDP packet, and allowing each respective UDP packet to reach the specific resource as a function of the unique user identifier extracted from the respective UDP packet.

Kits for amplifying DNA which include a priming oligonucleotide that hybridizes to a 3′-end of a DNA target sequence, a displacer oligonucleotide that hybridizes to a target nucleic acid containing the DNA target sequence at a position upstream from the priming oligonucleotide, and a promoter oligonucleotide that includes a region that hybridizes to a 3′-region of a DNA primer extension product that includes the priming oligonucleotide and a promoter for an RNA polymerase. The priming oligonucleotide does not include an RNA region that hybridizes to the target nucleic acid and is selectively degraded by an enzyme activity when hybridized to the target nucleic acid. The kits do not include a restriction endonuclease and oligonucleotides that include a promoter for an RNA polymerase are all modified to prevent the initiation of DNA synthesis therefrom.

A method of repairing a defect in an annulus fibrosus of an intervertebral disc, without excising the entire nucleus pulposus of the disc. The method includes inserting an introducer needle through the annulus fibrosus by puncturing the annulus fibrosus with the introducer needle, injecting an in situ curable, bio-compatible polymerizable or polymeric material composition into the disc through the introducer needle directly or indirectly so that the in situ curable composition contacts a defect in the annulus fibrosus; and curing said material in situ.

A gas fueled lighter having a compact storage configuration so as to be easily carried in a pocket or purse, the lighter actuated by sliding a longitudinal portion engaged to the body so as to extend said portion to form an extension having a free end, the free end configured to initiate a flame upon full extension from the body, the flame fueled by gas in the body and ignited by a piezo ignition switch. The preferred embodiment of the present invention is designed to provide an inexpensive, compact, easy to implement lighter providing the flame from an extension when in use, the extension sliding back to form a portion of the body when not in use. This safety feature not only provides a flame extended from the user's hand and body, it also provides an extension for lighting pilot lights, gas grills, fireplaces, and the like. The body of the preferred embodiment has a gas reservoir therein as well as the ignition and fuel valve, and further has a generally rectilinear configuration with at least a portion of the top configured to slide longitudinally to form the extension, the upper face of the top including a frictional area for placement of the user's thumb thereupon for sliding of the extension and initiation / cessation of the flame. The body may be rubberized for a better grip, and may include finger ridges for an enhanced grip of the system, and the overall body ideally has an ergometric design to facilitate comfortable and tactile operation.

Novel methods of synthesizing multiple copies of a target nucleic acid sequence which are autocatalytic are disclosed (i.e., able to cycle automatically without the need to modify reaction conditions such as temperature, pH, or ionic strength and using the product of one cycle in the next one). In particular, methods of nucleic acid amplification are disclosed which are robust and efficient, while reducing the appearance of side-products. In general, the methods use priming oligonucleotides that target only one sense of a target nucleic acid, a promoter oligonucleotide modified to prevent polymerase extension from its 3′-terminus and, optionally, a means for terminating a primer extension reaction, to amplify RNA or DNA molecules in vitro, while reducing or substantially eliminating the formation of side-pro ducts. The disclosed methods minimizes or substantially eliminate the emergence of side-products, thus providing a high level of specificity. Furthermore, the appearance of side-products can complicate the analysis of the amplification reaction by various molecular detection techniques. The disclosed methods minimize or substantially eliminate this problem, thus providing enhanced levels of sensitivity.

A beverage preparation machine comprising: a seat (5); an ingredient holder (13) that has a processing configuration and a transfer configuration; and a service unit (20, 30) having an operative position in the seat and being removable from the seat. A mechanical locking device (53) is provided to: mechanically detect a position of the service unit and mechanically prevent the ingredient holder from taking its processing configuration when the service unit is off its operative position; and / or mechanically detect a configuration of the ingredient holder and mechanically prevent removal of the service unit from the seat when the ingredient holder is in its processing configuration.