Instrumented networks, computer systems and platforms having target subjects (devices, transactions, services, users, organizations) are disclosed. A security
orchestration service generates runtime operational integrity profiles representing and identifying a level of
threat or contextual
trustworthiness, at near real time, of subjects and applications on the instrumented target platform. Methods and systems are disclosed for calculating security risks by determining subject reputation scores. In an embodiment, a
system receives a query for a reputation
score of a subject, initiates directed queries to external
information management systems to interrogate attributes associated with the subject, and analyzes responses. The
system receives a hierarchical subject reputation
score based on a calculus of risk and returns a reputation token. In another embodiment, a method provides real time attestation of a subject's reputation to a
service provider using an endpoint trust agent, and a trust orchestrator comprising a reputation broker and a trust broker.