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Skin barrier repairing compound, pre-essence and preparation method of pre-essence

A skin barrier and complex technology, applied in skin care preparations, skin diseases, drug combinations, etc., can solve problems such as ignoring skin barrier health, only focusing on efficacy, and difficult to solve deep skin problems, so as to achieve inflammation and discomfort Symptoms are fast and effective, and the effect of maintaining homeostasis and basic health

Active Publication Date: 2020-09-04
广州一一生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Currently commonly used skin care products for repairing the skin barrier have some drawbacks: First, they only focus on strengthening the efficacy, but ignore the health of the skin barrier. Only healthy skin can absorb nutrients better, and only healthy skin can stay away from various problems. In order to maintain youthful beauty for a long time
The second is to only focus on a single barrier maintenance, but ignore other barriers of the skin, the skin surface looks good, and deep skin problems are difficult to be solved

Method used

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  • Skin barrier repairing compound, pre-essence and preparation method of pre-essence
  • Skin barrier repairing compound, pre-essence and preparation method of pre-essence
  • Skin barrier repairing compound, pre-essence and preparation method of pre-essence

Examples

Experimental program
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Effect test

preparation example 1

[0068] This preparation example prepares a kind of sea fennel callus culture, and the preparation method of described sea fennel callus culture filtrate comprises the following steps:

[0069] (1) Callus induction culture: sea fennel explants were inoculated into agar medium for callus induction culture, the temperature of the induction culture was 20°C, and the time of the induction culture was 14 days, and the callus was obtained. injured tissue;

[0070] (2) Callus particle suspension culture: inoculate the callus obtained in step (1) into MS medium, and carry out shaking culture in a shaking incubator at a speed of 100 r / min, and the temperature of the shaking culture is 20°C , the time of the shaking culture is 14 days to obtain the proliferation callus;

[0071] (3) Expanded culture of callus: Inoculate the proliferated callus obtained in step (2) into a sterile cell bag for expanded culture, the temperature of the expanded culture is 25°C, and the time of the expanded ...

preparation example 2

[0074] This preparation example prepares tetrahydromethylpyrimidine carboxylic acid, and the preparation method of described tetrahydromethylpyrimidine carboxylic acid comprises the following steps:

[0075] (A) Cultivation of desert halophilic bacteria: the desert halophilic bacteria were inoculated in SCDLP liquid medium, and cultivated with a rotating speed of 1000r / min in a shaking incubator, and the temperature of the cultivation was 20°C. The time is 48h, and the desert halophilic bacteria cell is obtained;

[0076] (B) Osmotic pressure shock: the desert halophilic bacteria bacterium that step (A) obtains is resuspended in hyperosmotic pressure solution (the hyperosmotic pressure solution comprises: 18% sucrose, 0.1% EDTA, remaining Soak in water) for 1 hour, filter to obtain the precipitated desert halophilic bacterial cell;

[0077] (C) Electrodialysis: the desert halophilic bacterial thalline that step (B) obtains is processed by electrodialysis to obtain tetrahydrom...

preparation example 3

[0079] This preparation example prepares a kind of hydrolyzed red algae extract, the preparation method of described hydrolyzed red algae extract comprises the following steps:

[0080] (a) Extraction: wash, crush and pass through a 100-200 mesh sieve to obtain the red algae powder; add water to the red algae powder and perform an extraction at 70°C, and the time for the first extraction is 10 hours , the mass ratio of the water and the red algae powder is 20:1, the primary extract is obtained, the primary extract is filtered and then concentrated, then the volume ratio concentration is added to an aqueous ethanol solution of 80% for secondary extraction, and the precipitate is left to stand, Obtain red algae polysaccharide crude material;

[0081] (b) Hydrolysis: After dissolving the rough material of red algae polysaccharide obtained in step (a), add 30wt% aqueous hydrogen peroxide solution, mix and stir for 1 hour at 50° C. to obtain hydrolyzed red algae extract;

[0082] ...

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Abstract

The invention provides a skin barrier repairing compound, a pre-essence and a preparation method of the pre-essence. The skin barrier repairing compound is prepared from a skin barrier repairing composition, madecassoside, a grape leaf extract, a chondrus crispus extract, glycosphingolipids and glycolipids, the skin barrier repairing composition is prepared from crithmum maritimum callus culture filtrate, tetrahydromethyl pyrimidinecarboxylic acid and a hydrolyzed red alga extract; and the pre-essence comprises the following components in percentage by mass: 1-10% of the skin barrier repairingcompound, 10-30% of a humectant, 1-10% of an emollient, 1-5% of an emulsifier and the balance of water. The skin barrier repairing compound can effectively balance a microbial barrier, stabilize a keratinous barrier and strengthen an immunity barrier, so that the skin is healthy and stable. The pre-essence prepared from the skin barrier repairing compound can effectively regulate cutin renewal, strengthen the skin cutin barrier and improve the skin resistance.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to a skin barrier repair compound, a muscle base liquid and a preparation method thereof. Background technique [0002] The skin is the natural barrier of the human body surface, and there are many microorganisms. The micro-ecological balance of the skin maintains the stability of the skin environment and plays an important role in the health of the body. Healthy skin can effectively retain moisture, thereby maintaining good elasticity and a shiny appearance of the skin. However, the skin is affected by the living environment and its own physiological conditions, and the skin may have skin problems such as sensitivity, dryness and peeling, excessive oil secretion, pigmentation, sagging and aging skin, red bloodshots, etc. The main reason is that the skin barrier is damaged. The skin barrier is a protective structure jointly constructed by the stratum corneum and the s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9717A61K8/9789A61K8/68A61K8/63A61K8/49A61Q19/00A61P29/00A61P17/00
CPCA61K8/4953A61K8/63A61K8/68A61K2800/592A61K2800/5922A61K2800/782A61Q19/00A61K8/9717A61K8/9789A61P17/00A61P29/00
Inventor 温伟红徐洁琼容惠程文曲
Owner 广州一一生物技术有限公司
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