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46 results about "Rubia" patented technology

Rubia is a genus of flowering plants in the family Rubiaceae. It contains around 80 species of perennial scrambling or climbing herbs and subshrubs native to the Old World. The genus and its best-known species are commonly known as madder, e.g. Rubia tinctorum (common madder), Rubia peregrina (wild madder), and Rubia cordifolia (Indian madder).

Oral liquid of cuttle bone and rubia root for anormal metrorrhagia

A staltic Chinese medicine in the form of oral liquid for treating the abnormal metrorrhagia is prepared from 20 Chinese-medicinal materials including cuttlefish bone, madder, astragalus root, Chinese angelica root, etc. Its advantage is high curative effect.
Owner:李克成

Ostrichoil for treating wound and burn and scald, and tibet medicine ointment and preparing method

The present invention relates to an ostrich oil and Chinese Tibetan medicine ointment for effectively using wound, burn and scald and its preparation method. Said invention includes the following components: 81g of dried rhizome of paris polyphylla, 81g of rubia root, 81g of Chinese angelica root, 100g of sanguisorba root, 150g of flavescent sophora root, 85g of rhubarb, 100g of phellodendron bark, 90g of giant knotweed rhizome and ostrich oil, the weight ratio of ostrich oil and above-mentioned all the Chinese Tibetan medicines extract is 2.5:1. Its preparation method includes the following steps: dissolving ostrich oil at 80deg.C, progressively adding the Chinese Tibetan medicines extract broken to 120 meshes into the dissolved ostrich oil according to the mixing ratio of 2.5:1, then adding small quantity of paraffin wax, quickly stirring them, uniformly mixing them, disinfecting and filling so as to obtain the invented finished product.
Owner:王桂欣 +1

Traditional Chinese medicine for treating breast hyperplasia and breast cancer

The invention relates to a traditional Chinese medicine for treating breast hyperplasia and breast cancer. The traditional Chinese medicine can be used for effectively solving the treatment medicinal problems of the breast hyperplasia and breast cancer. The technical scheme for solving the problems is as follows: the traditional Chinese medicine is prepared from radix curcumae processed with vinegar, trigone processed with vinegar, rhizoma zedoariae processed with vinegar, processed pangolin, seaweed, iphigenia indica, radix codonopsitis, astragalus root, fruit of glossy privet, honeysuckle, lithospermum, chrysanthemum, rhizoma cyper processed with vinegar, trichosanthes, rubia root, corydalis tuber processed with vinegar, uniflower swisscentaury root, rhizoma coptidis, processed vomiting nut, chilopod, rheum officinale, fried cowherb seed, fried mustard seed, tangerine seed, prepared frankincense, prepared myrrh, oarweed and paris polyphylla. The material medicines are crushed and prepared into pills by using water and dried, respectively. The material medicines are effectively combined and supported with each other to achieve the effects of detoxicating and resolving a mass, tonifying qi and dredging collaterals, and promoting blood circulation to remove blood stasis. Besides, the traditional Chinese medicine is effectively used for treating the breast hyperplasia and breast cancer, and is safe in medicine use, good in curative effect and innovative on medicines for treating the breast hyperplasia and breast cancer.
Owner:HENAN UNIV OF CHINESE MEDICINE

Dammarane triterpenoid glycoside compound as well as preparation method and application thereof

The invention discloses dammarane triterpenoid glycoside compounds as well as a preparation method and application thereof. The dammarane triterpenoid glycoside compounds are specifically three compounds which are separated from a rubiaceae rubia plant, namely Mycephala sinensis (Hemsl.) Craib, and the structural formula of the dammarane triterpenoid glycoside compounds is shown in the specification. Tests show that the dammarane type triterpenoid saponin with the structure shown in the formula 2 has sweetness, the sweetness of the dammarane type triterpenoid saponin is about 200 times that ofcane sugar, and the dammarane type triterpenoid saponin can be used as a sweetening agent and applied to various industries such as food and medicines.
Owner:GUANGXI INST OF BOTANY THE CHINESE ACAD OF SCI

Traditional Chinese medicine composition for treating and regulating dysmenorrhea

The invention provides a traditional Chinese medicine composition for treating and regulating dysmenorrhea, which comprises the following traditional Chinese medicine raw materials: common bluebeard herb, dragon's blood resin, fluorite, eucommia bark, suakwa vegetable sponge, cassia, motherwort, folium citri reticulatae, rubia root, burreed rhizome, dandehon herb, flower of lilac daphne, xiaohongteng, rhizome of Chinese ligusticum, corydalis tuber, ricepaper pith, prunella spike, areca seed, fenugreek seed, ledebouriella root, dodder seed, achyranthes root, toosendan fruit, asarum herb, loranthus, cynomorium and myrrh. The traditional Chinese medicine composition is prepared after repeated validation of clinical tests, conforms to the traditional Chinese medical theories, and has the effects of activating blood, dissolving stasis, removing blood stasis, dissipating masses, soothing the liver, regulating qi, relieving pain, dredging the channels and collaterals, supplementing qi and promoting the secretion of saliva or body fluid; the traditional Chinese medicine composition is prepared according to an ancestral secret recipe and years of treatment experiences, exerts the functions of nourishing blood, regulating menstruation, dispelling cold, activating qi, clearing and activating the channels and collaterals, regulating qi and blood and clearing damp-heat, can be acted at the lesions and uterine cavity, and has good curative effect for treating the patients with dysmenorrhea and irregular menstruation; and the regularity in menstrual period is adjusted under the progressive action of the medicament, and the menstruation disorder gradually returns to normality.
Owner:王璇

Insecticide

InactiveUS20030082244A1Highly safe to human beings andExterminating and controlling insectCosmetic preparationsBiocideRubiaDiaporthales
The insecticide of the present invention comprises at least one member selected from a plant, an extract of the plant, and an ooze (or exudate) of the plant, wherein the plant belongs to at least one genus selected from the group consisting of the genus Geranium, the genus Morus, the genus Artemisia, the genus Diospyros, the genus Crataegus, the genus Curcuma, the genus Rubia, the genus Polygonum, the genus Gardenia, the genus Cornus, the genus Uncaria, the genus Rheum, the genus Terminalia and the genus Saussurea. The extract may be a substance extracted with at least one member selected from the group consisting of water and a hydrophilic solvent. The insecticide exhibits high insecticidal and insect-controlling activity against insects (e.g., sanitarily injurious insects, insects injurious to houses and particularly to timber such as termites), being highly safe to human beings and animals and not adversely affecting the environment.
Owner:JAPAN ENVIROCHEM

Naphthoquinone dimer and preparation method and applications thereof

The invention discloses a naphthoquinone dimer separated from Rubia plant, a pharmaceutical composition taking the naphthoquinone dimer as an active ingredient, an Nf-kB signal pathway inhibitor taking the naphthoquinone dimer as an active ingredient, a preparation method, and applications of the naphthoquinone dimer in drugs for treatment and prevention of related inflammatory diseases and cancers activated by abnormality of an Nf-kB signal pathway, belonging to the technical field of pharmaceuticals. The Rubioncolin C (1) is a naphthoquinone dimer separated from Rubiapodantha D., and has in vitro and vivo anti-tumor and Nf-kB signal pathway inhibition activity. The naphthoquinone dimer can be applied in preparation of anti-tumor pharmaceutical preparation and precursor drugs, and has the advantages of being low in preparation cost, low in toxicity, good in anti-tumor effect, and the like.
Owner:CHINA PHARM UNIV +1

Skin lightening composition comprising an extract of plants from the families of symplocos or rubia

A cosmetic skin lightening composition, comprising 0.1-50 % by weight of an extract of plants from the families of Symplocos, Rubia or a mixture thereof.
Owner:CONOPCO INC D B A UNILEVER

Herbal medicament for treating piglet white scour

The invention discloses a herbal medicament for treating piglet white scour. The herbal medicine is prepared from Cierbao, lily and rubia root. A liquid medicament is obtained with a water decoction method. The herbal medicament is mixed with a feed for feeding a sow two weeks before delivery of the sow, so that a prevention effect can be achieved; and the liquid medicament is fixed into feed for feeding the sow after the delivery of piglets and before white scour occurs, so that piglet white scour can be prevented, and can be healed by increasing the medicament amount after occurrence.
Owner:杨昌标

Zhulan medicated liquor

The present invention discloses compound pogonia japonica medicinal liquor for effectively curing the diseases of rheumatalgia, traumatic injuries, rheumatic arthritis, rheumatic gout, arthralgia due to wind-cold-dampness, lumbago due to pathogenic wind-dampness and others. It is made up by using Chinese medicinal materials of pogonia japonica, yiweiyao root, yeluma root, rubia maillardi, pachysandra axillaris and white liquor as raw material through a certain preparation process.
Owner:蓝子花

Radix rubiae cyclic peptide compound and preparation method thereof

The invention discloses a Radix rubiae cyclic peptide compound and a preparation method thereof. The preparation method of the Radix rubiae cyclic peptide compound comprises the following steps: usingstems and / or leaves of Rubia hangii as raw materials, obtaining an extract of the Rubia hangii, and separating and purifying the obtained extract through a macroporous resin column, a silica gel column and a high-speed counter-current chromatograph to obtain the Radix rubiae cyclic peptide compound. Experiment results of the applicant show that the compound has strong binding capacity with coronavirus targets (S protein, 3CL protein, DC-SIGN receptor protein and ACE2 receptor protein), HIV targets (HIV-1 protein) and hepatitis B virus targets (Bcl-2, Bcl-xL), so the component has potential medicinal value for novel coronaviruses, HIV viruses and hepatitis B viruses. The compound is expected to be used for preparing anti-coronavirus drugs and / or anti-HIV and / or anti-hepatitis B virus drugs.
Owner:GUANGXI INST OF BOTANY THE CHINESE ACAD OF SCI

Medicine for fast treating inflammatory demyelinating polyneuropathy

The invention relates to medicine for fast treating inflammatory demyelinating polyneuropathy. The medicine is prepared from the following ingredients in parts by weight: 9 to 14 parts of oryzanol, 6 to 11 parts of clematis chinensis, 5 to 10 parts of radix paeoniae alba, 6 to 12 parts of ligusticum chuanxiong hort, 4 to 11 parts of scorpio, 5 to 10 parts of earthworms, 6 to 9 parts of asarum sieboldii, 5 to 8 parts of claoxylon indicum hassk, 5 to 11 parts of spilanthes paniculata, 6 to 12 parts of rubia kaematantha airy-shaw, 5 to 10 parts of phellodendron amurense, 5 to 10 parts of conical redpepper fruit, 6 to 11 parts of melodinus suaveolens, 5 to 12 parts of cynomorium songaricum, 5 to 10 parts of boxthorn roots, 6 to 11 parts of eucommia ulmoides oliver, 5 to 10 parts of magnolia officinalis, 4 to 8 parts of semen euphorbiae lathyridis and 5 to 9 parts of solidago canadensis. The medicine has a good treatment effect on the inflammatory demyelinating polyneuropathy.
Owner:哈尔滨泉兴科技有限公司

Agentia for treating blood-stasis type non-stop lochia after delivery

The invention relates to an agentia for treating blood-stasis type non-stop lochia after delivery. The agentia is prepared by the following substances in parts by weight: 1-10 parts of assorted Chinese herbal tea, 1-10 parts of cirsium japonicum, 10-20 parts of radix pittospori, 10-20 parts of Chinese alpine rush, 1-10 parts of radix rubiae, 1-10 parts of tangerine pith, 15-30 parts of sporobolus fertilis, 10-20 parts of rubia membranacea root, 1-10 parts of silkworm larva, 1-10 parts of euonymus porphyreus, 5-15 parts of panax japonicus, 1-10 parts of radix cyathulae, 10-20 parts of potentilla bifurca, 1-10 parts of resina liquidamberis, 10-20 parts of orixa japonica, 10-20 parts of bermuda grass, 5-15 parts of herba lycopi, 1-10 parts of persimmon bark, 1-10 parts of cattail roots, 10-20 parts of oil tea camellia leaves, 1-10 parts of liquorice and 10-20 parts of ginkgo roots. The agentia has the main functions of activating blood and dispersing blood stasis and cooling blood and removing blood stagnation, also has the auxiliary functions of benefiting qi and generating blood, clearing heat and removing toxicity and nourishing kidney and yin, has obvious effect for treating the blood-stasis type non-stop lochia after delivery and is worthy of being promoted clinically.
Owner:王俊芝

Zuanshanfeng guttage pill and preparing method

The Chinese medicine composite zuanshanfeng dripping pills preparation for curing the diseases of cold pain in the lumbus and knees, numbness of the limbs and inhibited bending and stretching resulted from arthralgia due to wind-cold-dampress is made up by using extract of 7 Chinese medicinal materials of zuanshanfeng. berchemia sinica, rubia maillardi, clematis root, moghania root, millettia hirsutissima and alpinia japonica as raw material and pharmaceutical aueptable carrier through a certain preparation process.
Owner:北京博智绿洲医药科技有限公司

Bladder care irrigation solution and preparation method thereof

The invention discloses a bladder care irrigation solution and a preparation method of the solution. The bladder care irrigation solution is prepared from Chinese Wolfberry Root-bark, Paeonia alba, Radix Rehmanniae, Artemisia annua, Glossy Privet Fruit, Ecliptae Herba, Rubia cordiolia root, Cyperi Rhizoma and Radix Linderae. The preparation method comprises crushing the medicinal materials and distilling to obtain rectification liquid, performing water extraction and alcohol precipitation on the medicinal residues to obtain supernatant, mixing the rectification liquid and the supernatant, performing ultrafiltration, filling and sterilizing. Clinical experiments prove that the solution of the invention has hemostatic, antibacterial, analgesic and cystospasm-relieving effects, has no stimulation or allergic reaction, and is non-toxic to human beings. The irrigation solution can greatly reduce the use of antibiotics, and reduce the pain of patients with indwelling urethral catheterization.
Owner:鞠富霞

Traditional Chinese medicine composition mainly for treating uremia and preparation method thereof

The invention discloses a traditional Chinese medicine composition mainly for treating uremia. The composition is mainly prepared from, by mass, 9-13 parts of plantain herbs, 7-12 parts of selaginella nipponica, 6-11 parts of white ground elm, 8-14 parts of malva crispa leaves, 6-10 parts of lily, 5-9 parts of rubia yunnaensis, 7-13 parts of magnoliopsida verbenaceae, 10-14 parts of scouring rush, 8-15 parts of dandelion, 6-12 parts of phyllanthus urinaria, 9-14 parts of stellaria yunnanensis, 7-11 parts of litsea cupularis hemsl, 8-13 parts of creeping oxalis and 6-10 parts of aeschynomene indica. The composition is formed according to many years of clinical practice summary, has the effects of clearing heat, promoting diuresis, detoxicating and treating stranguria, and is remarkable in curative effect.
Owner:张相才

Externally applied traditional Chinese medicine for treating calcaneodynia

The invention discloses an externally applied traditional Chinese medicine for treating calcaneodynia, which comprises the following raw materials in parts by weight: 4-5 parts of Chinese redbud bark, 3-5 parts of rhizoma atractylodis, 5-8 parts of schisandra chinensis, 3-4 parts of fructus cnidii, 4-5 parts of tuberculate speranskia herb, 3-5 parts of radix cyathulae, 1-2 parts of geranium wilfordii, 1-2 parts of Chinese hydrangeavine, 8-10 parts of semen raphani, 5-6 parts of manis pentadactyla, 3-5 parts of snake slough, 1-2 parts of ganoderma lucidum, 10-12 parts of herba cistanche, 8-10 parts of pollen typhae, 1-2 parts of uniflower swisscentaury root, 2-4 parts of rubia, 1-2 parts of paniculate swallowwort root, 1-2 parts of common vetch, 4-5 parts of semen celosiae, 5-7 parts of chingma abutilon seed, and 1-2 parts of polygonum palmatum. The medicine has functions of dispelling wind, eliminating dampness, relaxing muscles and tendons, promoting blood circulation to arrest a pain, clearing and activating channels and collaterals, inducing resuscitation, and penetrating bones, is simple to prepare, good in absorption effect, significant in treatment effect and high in safety, has no side effect, and facilitates relieving a symptom of a patient timely.
Owner:黄萍

Traditional Chinese medicine decoction for treating thrombocytopenia

The invention discloses a traditional Chinese medicine decoction for treating thrombocytopenia. The traditional Chinese medicine decoction comprises the following raw materials in parts by weight: 5.5-6.5 parts of dried rehmannia root, 6-7 parts of astragalus root, 2-4 parts of glossy privet fruit, 6-8 parts of spatholobus stem, 2-4 parts of notoginseng, 1-3 parts of muskmelon skin, 6-8 parts of carbonized sanguisorba root, 4-6 parts of radix codonopsis pilosulae, 2-4 parts of black sesame seed, 4-6 parts of common dodder, 1-3 parts of giant knotweed rhizome, 6-8 parts of semen litchi, 2-4 parts of pteridium squilinum, 1-3 parts of rubia root, 5-7 parts of cortex lycii radicis, 3-5 parts of cordyceps sinensis, 2-4 parts of tuckahoe, 5-7 parts of rhizoma polygonati, 1-3 parts of purpleflower holly bark, 2-4 parts of doellingeria scaber root, 2-4 parts of clinopodium chinense, 1-3 parts of black soybean leaf and 4-6 parts of drymaria cordata. The Chinese medicinal composition disclosed by the invention has effects on clearing away heat and toxic materials, cooling blood to remove stasis, invigorating qi, nourishing Yin and tonifying the kidneys, is quick and effective in treating thrombocytopenia, high in cure rate and low in recurrence rate, does not have any toxic or side effects, and can improve human immunity and improve the physical quality of patients.
Owner:ANHUI PROVINCE YINGSHANG COUNTY HOSPITAL OF TRADITIONAL CHINESE MEDICINE

Herbal formulation for wound healing

The present invention pertains to a herbal formulation with highly potent wound healing properties, in humans and animals. The composition consists of aqueous extracts of Azadirachta indica, in a mixture of natural oils along with herbs viz. Berberis aristata, Curcuma longa, Glycyrrhiza glabra, Jasminum officinale, Picrorhiza kurrooa, Pongamia pinnata, Rubia folia, Saussurea lappa, Terminalia chebula, Trichosanthes dioica, Capsicum and Stellata wild in well-defined ratios. The invention also includes a process for preparing the formulation by extracting the water-soluble components from bark of Azadirachta indica.
Owner:SUNEV PHARMA SOLUTION

A traditional Chinese medicine composition for treating cancer and its preparation method, preparation and application

The invention discloses a traditional Chinese medicine composition as well as a preparation method, preparation and application thereof. The traditional Chinese medicine composition comprises 11-63 parts by weight of raw materials, 9-58 parts of Lobelia, 4-52 parts of Hedyotis diffusa, 13-76 parts of Dianchangshan leaves, 2-17 parts of Zijinlonggen 18~73 parts of Rubia root, 4~52 parts of Polygonum cuspidatum root, 19~75 parts of Imperata rhizome, 9~58 parts of Hatchling root, 11~63 parts of Gentiana and 5~57 parts of Prunella vulgaris, after pretreatment, extraction, Prepared by drying. The traditional Chinese medicine composition of the invention has the characteristics of multiple targets and multiple action channels, and has unique advantages in anti-cancer and anti-mutation. The traditional Chinese medicine composition of the invention has reasonable prescriptions, clear base sources of medicinal materials and clear application sites, scientific preparation method, clear and controllable quality indicators, high safety, remarkable curative effect, and broad application prospects.
Owner:KPC PHARM INC

Nutrient solution for removing heavy metal and drug residues in chicken body and preparation method thereof

The invention discloses a nutrient solution for removing heavy metal and drug residues in a chicken body and a preparation method thereof. The nutrient solution is characterized in that the active ingredients of the nutrient solution mainly comprise, by weight, 30-40 parts of dandelions, 20-25 parts of panax quinquefolius, 10-15 parts of lotus leaves, 5-10 parts of rubia membranacea, 5-10 parts oflemongrass herb, 2-5 parts of apricot kernels, 2-5 parts of radix codcnopsitis pilosulas, 1-3 parts of flos lonicerae and 1-3 parts of licorice roots. According to the nutrient solution, through a scientific proportion and a special preparation process, after fermentation of various traditional Chinese medicines, various natural compound active ingredients are generated, which can remove the heavy metal and drug residues in the chicken body, improve the chicken quality and improve the chicken taste, and the nutrient solution has the advantages of convenient use, a good use effect, no toxic orside effect, safety, stability and the like, and has good social and economic benefits.
Owner:广西妙天生物科技有限公司

Traditional Chinese medicine for treating primary bone lymphoma

The invention discloses a traditional Chinese medicine for treating primary bone lymphoma. The traditional Chinese medicine is prepared from the Chinese herbal medicines as follows: rubus alceaefolius, scutellaria indica, plumbago zeylanica, pyrolusite, cryptolepis buchananii, carthamus tinctorius fruits, roots and rhizomes of divaricate gynura, rubia membranacea roots, corydalis temulifolia, scilla scilloides, stems of shinygreen creeper, derris trifoliate, roots of Japanese glorybower, roots or leaves of apricot plum, hoya pottsii, tubers of caladium bicolor, ormosia henryi, securidaca inappendiculata and all-grass of pineleaf hedyotis. The traditional Chinese medicine adopts the all-natural Chinese herbal medicines as raw materials, treats both symptoms and root causes, is definite in curative effect, has no toxic or side effects and prevents the primary bone lymphoma from relapsing.
Owner:丁子涵

Traditional Chinese medicine for treating spleen insufficiency damp-heat type colpitis mycotica and preparation method of traditional Chinese medicine

The invention provides a traditional Chinese medicine for treating spleen insufficiency damp-heat type colpitis mycotica and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine comprises the following raw material medicines: rubia membranacea, psidium guajave leaves, rumexjaponicus leaves, aleuritopteris farinose, winkled marshweed, manglietia insignis, lobaria isidiosa, odontites vulgaris, lythrum salicaria, oxygraphis glacialis, viburnum macrocephalum stems, Japanese plum root bark, euphorbia lunulata, kirilow groundsel herb and asparagus gobicus. The traditional Chinese medicine has a definite treatment effect on spleen insufficiency type colpitis mycotica and is small in toxic and side effects and short in treatment course, and the disease is difficult to reoccur.
Owner:宗秀红

Traditional Chinese medicine moxibustion formula for treating hyperostosis, preparation method of traditional Chinese medicine and use method of traditional Chinese medicine

The invention relates to a traditional Chinese medicine for treating hyperostosis, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine moxibustion composition comprises rhizome of Chuanxiong, rhizoma corydalis, frankincense, myrrh, safflower carthamus, China rose, mulberry twig, caulis sinomenii, dried body of ground beetle, logwood, rhizoma drynariae, common clubmoss herb, large-leaved gentian, Chinese angelica, caulis spatholobi, rubia, forsythia, glabrous greenbrier rhizome, mature vinegar and wine. By the aid of the traditional Chinese medicine, the hyperostosis is remarkably treated, and the healed hyperostosis cannot recur.
Owner:苏忠和

Oral liquid of cuttle bone and rubia root for anormal metrorrhagia

A staltic Chinese medicine in the form of oral liquid for treating the abnormal metrorrhagia is prepared from 20 Chinese-medicinal materials including cuttlefish bone, madder, astragalus root, Chinese angelica root, etc. Its advantage is high curative effect.
Owner:李克成

Traditional Chinese medicine for treating breast hyperplasia and breast cancer

The invention relates to a traditional Chinese medicine for treating breast hyperplasia and breast cancer. The traditional Chinese medicine can be used for effectively solving the treatment medicinal problems of the breast hyperplasia and breast cancer. The technical scheme for solving the problems is as follows: the traditional Chinese medicine is prepared from radix curcumae processed with vinegar, trigone processed with vinegar, rhizoma zedoariae processed with vinegar, processed pangolin, seaweed, iphigenia indica, radix codonopsitis, astragalus root, fruit of glossy privet, honeysuckle, lithospermum, chrysanthemum, rhizoma cyper processed with vinegar, trichosanthes, rubia root, corydalis tuber processed with vinegar, uniflower swisscentaury root, rhizoma coptidis, processed vomiting nut, chilopod, rheum officinale, fried cowherb seed, fried mustard seed, tangerine seed, prepared frankincense, prepared myrrh, oarweed and paris polyphylla. The material medicines are crushed and prepared into pills by using water and dried, respectively. The material medicines are effectively combined and supported with each other to achieve the effects of detoxicating and resolving a mass, tonifying qi and dredging collaterals, and promoting blood circulation to remove blood stasis. Besides, the traditional Chinese medicine is effectively used for treating the breast hyperplasia and breast cancer, and is safe in medicine use, good in curative effect and innovative on medicines for treating the breast hyperplasia and breast cancer.
Owner:HENAN UNIV OF CHINESE MEDICINE

Rubiaceae type cyclic peptide diglycoside and its preparation method and application

ActiveCN109134618BNovel structureGood prospects for technology applicationAntipyreticAnalgesicsCyclic peptideRubia
The invention discloses a rubiaceae type cyclic peptide diglucoside as well as its preparation method and application. The preparation method of the Rubiaceae type cyclic peptide diglycoside is as follows: using the stem and / leaf of the Rubiaceae Rubio genus Arthropodium as raw materials to obtain its extract, and the obtained extract is sequentially passed through a macroporous resin column, a silica gel column, a reversed-phase Silica gel column separation and purification, namely; when separated and purified by a macroporous resin column, the eluent is a mixed solvent composed of methanol or ethanol and water; when separated and purified by a silica gel column, the eluent is composed of chloroform and methanol mixed solvent; when separated and purified by a reverse-phase silica gel column, the eluent is a mixed solvent composed of methanol or acetonitrile and water. The applicant's experimental results show that the above-mentioned Rubiaceae type cyclic peptidoside has inhibitory activity of NF-κB signaling pathway and can be used as an inhibitor of NF-κB signaling pathway. The Rubiaceae type cyclic peptidoside has a structure shown in the following formula (I):
Owner:GUANGXI INST OF BOTANY THE CHINESE ACAD OF SCI
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