44 results about "Rubiaceae" patented technology

The invention discloses an alcohol extractable matter of paederia scandens of Rubiaceae plant, which is characterized by the following: extracting iridoid glycosides compound as effective component; displaying obvious analgesic and anti-inflammatory action when the content of paederia scandensin and paederia scandensin acid methyl ester at 10-90% respectively; improving the analgesic and anti-inflammatory action when the content of paederia scandensin and paederia scandensin acid methyl ester at 20-60% respectively; displaying the best analgesic and anti-inflammatory action when the content rate of paederia scandensin and paederia scandensin acid methyl ester at 5: 1-1: 5. The invention has similar analgesic action to opium drug without habituation.

The invention provides a method for efficiently separating crocetin from fruits of rubiaceous plants and gardenia (stenophyllous gardenia, spoonleaf gardenia, gardenia hainanensis, gardenia sootepensis and gardenia) plants, saffron and saffron tissue cultures. The crocetin can be prepared by the method, and meanwhile, the gardenia yellow pigment and the saffron pigment can be prepared. The method comprises the following steps: extracting the pigment of gardenia fruits (the saffron and the saffron tissue cultures) through acid water or directly extracting raw materials through alkaline water, then carrying out water liquid acidification, then extracting ethyl acetate to obtain a crocetin crude product, and recrystallizing the crude product through different solvents to obtain a crocetin pure product. The crocetin, the gardenia yellow pigment and the saffron pigment provided by the invention can be applied in preparing cardiovascular and cerebrovascular disease medicaments, gynecological disease medicaments, tumor adjuvant therapy medicaments and foods. The method of the invention has reasonable design, the crocetin, the gardenia yellow pigment and the saffron pigment can be obtained in large scales and have high yield, and the method is quite suitable for industrialized production.

The invention provides a rubiaceae-type cyclopeptide taken as a novel Hedgehog signal channel inhibitor as well as a preparation method and an application of the rubiaceae-type cyclopeptide in preparation of a medicine for treating and preventing relevant cancers activated by the abnormity of Hedgehog signal channels. The rubiaceae-type cyclopeptide is prepared by the condensation of one D-alpha-alanine, one L-alpha-alanine, three substituted N-methyl-L-alpha-tyrosines and one L-alpha-amino acid of another type via peptide bonds, wherein six amino acids are condensed into an eighteen-membered rings; and benzene rings between two adjacent tyrosines are connected via an oxygen bridge so as to form a fourteen-membered ring.

The invention discloses a crucian feed comprising the following raw materials: by weight, 10-12 parts of miscellaneous fish meal, 30-35 parts of rapeseed meal cake, 12-15 parts of soybean meal, 4-6 parts of freshwater shrimp powder, 4-5 parts of corn protein powder, 30-35 parts of vinasse, 20-24 parts of strong flour, 1-2 parts of lecithin, 3-5 parts of black bean, 2-3 parts of red jujube, 1-2 parts of rock sugar, 2-3 parts of bulbophyllum radiatum, 1-2 parts of isodon amethystoides, 3-4 parts of monochasma savatieri Franch. ex Maxim, 2-3 parts of polyalthia nemoralis A.DC., 3-4 parts of rubiaceae borreria stricta, 1-2 parts of arundina chinensis and 2-3 parts of a feeding promoting agent; the crucian feed is reasonable in nutritional component ratio, suitable for eating by crucian to quicken growth speed, not easy to loose in the water, convenient for the crucian to taking in for eating, less in waste, and less in water pollution, effectively improves the meat quality and nutrition values of the cultured crucian, and can promote the growth of the crucian.

The invention provides a rubiaceae type cyclopeptide compound RA-V (1) and a glycoside RA-XII (2) thereof as a tumor metastasis inhibitor, a drug composition with the rubiaceae type cyclopeptide compound and the glycoside as active ingredients, a preparation method of the compound and an application of the compound to preparation of anti-tumor metastasis drugs. The method can be used for obtaining cyclopeptide through rapid separation, is less in sample loss, relatively low in cost and convenient to operate, has good controllability and repeatability, ensures that solvents can be recycled, and is suitable for industrial production.

The invention discloses a spleen-invigorating, kidney-tonifying, nutritional and health-care sausage and a manufacturing method thereof. The sausage comprises the following raw materials: pork, millet, Gorgon fruit, dogwood, okra, submicron Chinese dodder seed powder, submicron Poria cocos powder, bighead atractylodes rhizome, tree peony bark, Rubiaceae Borreria stricta, fructus broussonetiae, tomentoseflower larkspour root, fragrant solomonseal rhizome, dendrobium, pomegranate rind, hance brandisia herb, soy, cooking wine, mature vinegar, salt, white sugar, chilli powder, mint leaf, fresh lemon leaf and a proper amount of rapeseed oil. According to the invention, pork is used as a raw material, components like millet, Gorgon fruit and dogwood are added, so the sausage is capable of reinforcing the kidney, nourishing the liver, strengthening the stomach, resisting bacteria and reducing blood sugar; meanwhile, traditional Chinese medicinal health-care components are added, so the sausage has a health-care function, wherein the root of tomentoseflower larkspour can supplement vacuity, nourish the kidney, dispel wind, eliminate dampness, invigorate blood circulation, regulate menstruation, tonify the kidney and strengthen the bones, the hance brandisia herb is capable of nourishing the liver and the kidney, clearing the liver and improving eyesight; thus, the sausage is applicable to a population with spleen-deficiency and kidney-deficiency.

The invention discloses a vegetable noodle, which is prepared from the following raw materials by weight: 90-100 parts of wheat, 50-60 parts of soybeans, 30-40 parts of brown rice, 25-30 parts of Chinese chestnut, 20-30 parts of lettuce, 20-30 parts of cabbage, 25-35 parts of wax gourd, 15-20 parts of dried mushroom, 30-40 parts of a pork ribs soup, 1-2 parts of chestnut leaf, 1-3 parts of glutinous rehmannia leaf, 1-2 parts of caulis bambusae in taeniam, 1-2 parts of Rubiaceae Borreria stricta, 1-2 parts of a food additive and a proper amount of water. The noodle provided by the invention employs wheat, soya bean and brown rice as the main raw materials; the soybean has the effects of invigorating spleen, benefiting Qi, easing the middle, moisturizing dryness, nourishing blood, lowering cholesterol, alleviating water retention and resisting cancer; brown rice has the effects of strengthening the spleen and stomach, supplementing the center and boosting qi, regulating the five internal organs, calming the nervous and promoting digestion and absorption; the additional lettuce has the effects of dredging, reducing accumulation, descending qi, strengthening the body, resisting cancer, widening intestines and relaxing bowels; wax gourd has the effects of moistening lung, promoting the secretion of saliva or body fluid, reducing phlegm, quenching thirst, inducing diuresis to reduce edema, clearing away summer heat, detoxifying and expelling pus; and dried mushroom has the effects of preventing and curing cold, resisting cancer, lowering cholesterol and preventing the liver cirrhosis.

The method herein describes a process for the preparation and extraction of components from plants of the family Rubiaceae indigenous to South America, also known as Cat's Claw or Uña de gato. Cat's claw is an ethnomedicine that contains a variety of constituents, some of which have opposing actions. Oxindole and pentacyclic alkaloids have been proposed to be constituents that stimulate immune function, whereas polar constituents act to suppress immune response. An extract that was devoid of the aforementioned alkaloids would avoid opposing actions that may negate effectiveness or limit therapeutic outcome.

The invention provides a rubiaceae-type cyclopeptide compound rubiyunnanin F(8), a pharmaceutical composition with the compound as an active component, as well as a preparation method and application of the compound. The invention provides the preparation method of the compound and application of the compound in preparation of anti-herpes simplex virus type I (HSV-1) medicines.

The invention discloses a method for extracting catechin, comprising the following steps: (1), a raw material of rubiaceae mitragynaKorth plant cap core wood is subjected to cold soaking by using a solvent at room temperature after being dried and pulverized, an extract is obtained after the reagent is recovered by decompression, the extract is suspended in water, and sherwood oil, ethyl acetate and normal butanol are sequentially used for carrying out extraction; (2), an extract of the ethyl acetate is packed by silica gel of 60-100 meshes according to the weight ratio of 1 to 30 after sample stirring, the sherwood oil and acetone are eluted according to the volume ratio of 9:1-10:1, thin-layer detection is carried out, the similarities are combined, the solvent is recovered by decompression, and a crude product of catechin is obtained; and (3), the acetone is added into the crude product, the mixture is heated, the acetone is gradually added into the mixture until the crude product is dissolved, aether with the volume of one tenth to one ninth of the volume of the acetone is added into the mixture, and crystals are separated out by standing and are filtered to obtain a pure product of the catechin. The invention has simple extracting method, abundant sources of the raw materials and low cost, a catechin compound obtained by extracting has extensive bioactivity, a catechin monomer is obtained by extracting, the solvent used in the extracting process can be recycled, the extracting quantity is large and industrial production can be realized. By adopting the method, the extracting efficiency is high, and the yield reaches 50-90 percent.

The invention provides an open-loop rubiaceae-type cyclopeptide, a pharmaceutical composition taking the open-loop rubiaceae-type cyclopeptide as an active ingredient, an inhibitor taking the open-loop rubiaceae-type cyclopeptide as an NF-kappa b signal pathway, a preparation method of the open-loop rubiaceae-type cyclopeptide and an application of the open-loop rubiaceae-type cyclopeptide in a medicine used for treating and preventing inflammatory diseases and cancers related to abnormal activation of the NF-kappa b signal pathway. The open-loop rubiaceae-type cyclopeptide is a cyclic compound formed by condensing one D-alpha-aminopropionic acids, two L-alpha-aminopropionic acids and three substituted N-methyl-L-alpha-tyrosines by virtue of peptide bonds; and the open-loop rubiacea-type cyclopeptide with the structural formula (1-3) is an optimized NF-kappa b signal pathway inhibitor.

The invention discloses a traditional Chinese medicine for treating prosopalgia. The traditional Chinese medicine is prepared from white-flower schefflera octophylla, frangrant daphne flower, ficus pumila, Chinese ixora flower, radix curcumae, tangerine seed, radix rubiaceae, radix curcumae longae, bauhinia seed, anise and liquorice. The traditional Chinese medicine can be clinically used for treating the prosopalgia.

The method herein describes a process for the preparation and extraction of components from plants of the family Rubiaceae indigenous to South America, also known as Cat's Claw or U ña de gato. Cat's claw is an ethnomedicine that contains a variety of constituents, some of which have opposing actions. Oxindole and pentacyclic alkaloids have been proposed to be constituents that stimulate immune function, whereas polar constituents act to suppress immune response. An extract that was devoid of the aforementioned alkaloids would avoid opposing actions that may negate effectiveness or limit therapeutic outcome.

The invention discloses a piglet fattening feed and a production method thereof, the piglet fattening feed comprises the following materials by weight: 250-300 parts of soybean meal, 200-250 parts of flour, 200-230 parts of malt powder, 150-200 parts of duck feather powder, 70-80 parts of mushroom powder, 50-60 parts of squid paste, 40-50 parts of buckwheat powder, 20-30 parts of whole milk powder, 5-6 parts of tremella, 3-4 parts of lactose, 20-25 parts of fresh celery, 25-30 parts of cucumber, 2-3 parts of soy sauce, 1-2 parts of vinegar, 2-3 parts of semen raphani, 1-2 parts of rubiaceae borreria stricta, 2-3 parts of astragalus membranaceus, 1-2 parts of aloe leaf, 1-2 parts of asiatic bilberry, 20-30 parts of zea Mexicana, 10-20 parts of reed leaves, 110-20 parts of fresh sugarcane leaves, 20-30 parts of straw bran, 2-3 parts of leaf mold, 3-4 parts of talcum powder, 15-30 parts of an attractant and proper amount of water. The piglet fattening feed has the features of aromatic odor, crispy taste, rich nutrient, and the like, piglets fed by the feed are high in appetite, fast in growth, and short in growth cycle, and the feed enhances the piglet disease resistance, and improves the benefits of pig breeding.

The invention discloses a preparation method of rubiaceae morinda citrifolia powder with an anti-fatigue effect. The method comprises the following steps of: (1) pretreatment: washing fresh rubiaceae morinda citrifolia fruits clean, drying and smashing for later use; (2) extracting solution preparation: mixing the fruit powder with alcohol, extracting with hot water, cooling, filtering and drying residues for later use; mixing the residues with distilled water, extracting in a hot water bath, cooling and filtering to obtain a filter liquor for later use; and (3) drying and molding; concentrating the filter liquor to a corresponding density in vacuum, spraying and drying to obtain rubiaceae morinda citrifolia spray powder. The method has the advantages of simple process, high extraction rate and no pollution. Proved by an animal experiment, the rubiaceae morinda citrifolia extractive can be used for prolonging the swimming time of a rat and has a good anti-fatigue effect.

The invention discloses dammarane triterpenoid glycoside compounds as well as a preparation method and application thereof. The dammarane triterpenoid glycoside compounds are specifically three compounds which are separated from a rubiaceae rubia plant, namely Mycephala sinensis (Hemsl.) Craib, and the structural formula of the dammarane triterpenoid glycoside compounds is shown in the specification. Tests show that the dammarane type triterpenoid saponin with the structure shown in the formula 2 has sweetness, the sweetness of the dammarane type triterpenoid saponin is about 200 times that ofcane sugar, and the dammarane type triterpenoid saponin can be used as a sweetening agent and applied to various industries such as food and medicines.

The invention discloses litchi diet tea which is made from raw materials in parts by weight as follows: 30-40 parts of litchis, 60-70 parts of grapefruit, 20-30 parts of broadleaf holly leaves, 15-20 parts of stevia rebaudian leaves, 10-15 parts of jade beauty, 6-8 parts of stachys sieboldii, 3-4 parts of puerarin, 4-5 parts of rubiaceae borreria stricta, 2-3 parts of dandelion, 1-2 parts of common sage herbs, 1-2 parts of sweet broomwort herbs, 1-2 parts of fortune eupatorium herbs, 3-4 parts of honeysuckle, 1-2 parts of sweet wormwood herbs, 2-3 parts of dwarf lilyturf roots and 4-6 parts of rice vinegar. Various raw materials with weight loss and beauty efficacy are processed and prepared into a tea drink, and the diet tea is safe, green and free of additives, not only has rich fruity flavor and simple tea fragrance, but also has efficacy of removing heat to promote salivation, wetting a user's whistle to relieve a cough, tonifying heart, soothing the nerves, allaying tiredness, nourishing the liver, losing weight, maintaining beauty and keeping young and the like; and the prepared tea drink smells fragrant and tastes sweet, and is low in cost, free of side effect and remarkable in weight loss, and weight regaining is not prone to happen after a user stops drinking the tea.

The invention discloses alcohol effect dispelling fruit yogurt. The yogurt is prepared from the following raw materials in parts by weight: 70-80 parts of pomegranate, 30-40 parts of grape, 20-30 parts of tomato, 20-30 parts of olive, 60-70 parts of watermelon, 3-5 parts of kudzuvine root, 2-3 parts of folium apocyni veneti, 1-2 parts of apple blossom, 2-3 parts of sweet potato leaf, 2-3 parts of bamboo shaving, 1-2 parts of cushaw stem, 2-4 parts of rubiaceae borreria stricta, 1-2 parts of semen oroxyli, 1-3 parts of rhizoma phragmitis, 15-20 parts of acacia honey, 6-8 parts of rice vinegar and 400-500 parts of fresh milk. The yogurt prepared by processing raw materials with alcohol effect dispelling effect is richer in nutrition and more delicious in taste, can be used for reducing hurt of alcohol on a human body while effectively dispelling alcohol effect, and has the effects of arresting vomiting and dissipating swelling, strengthening spleen and harmonizing stomach, tonifying liver and nourishing kidney, promoting body fluid production and quenching thirsty, clearing heat and promoting diuresis.

The invention provides a method of wild-growth-imitation planting of polyporus umbellatus in the Pu-er mountainous area and belongs to the planting methods of polyporus umbellatus. The method comprises the following steps: firstly, selecting a wild forest satisfying the conditions that the dominant tree species (such as fagaceae, rubiaceae and theaceae) in primitive broad-leaved forests are present, under-forest soil is thick in soil humus, the gradient is greater than 20 degrees and the drainage is convenient; secondly, digging strip-shaped pits in the under-forest ground, which satisfies the above-mentioned conditions, in the selected area for planting polyporus umbellatus; thirdly, according to the requirement for polyporus umbellatus spawns, selecting wild or artificially-planted white polyporus umbellatus or grey polyporus umbellatus with lighter colors, the weight of each being greater than 15g; fourthly, digging strip-shaped pits 80cm long and wide and 30cm deep in the ground, paving the bottoms of the pits with tree leaves 5cm thick, placing sticks on the tree leaves at intervals of 3-5cm, placing honey fungi and polyporus umbellatus spawns close to the sticks, placing sandy soil of 10cm thereon for covering, laying tree leaves thereon, and digging drainage trenches around the pits for facilitating drainage of accumulated water in rainy days; fifthly, taking no special management measures in the growth process and only adding 2-3 times of manual forest water spray and surface irrigation in specially-dry seasons; sixthly, harvesting the medicinal materials after the polyporus umbellatus grow for three years.

The invention discloses rubiaceae-type cyclopeptide bioside, a method for preparing the same and application of the rubiaceae-type cyclopeptide bioside. The method for preparing the rubiaceae-type cyclopeptide bioside includes acquiring extract from stems and / or leaves of rubiaceae rubia plants rubia hangii; sequentially separating and purifying the obtained extract by macroporous resin columns, silica gel columns and reverse phase silica gel columns to obtain the rubiaceae-type cyclopeptide bioside. Eluents are mixed solvents with methanol or ethyl alcohol and water when the extract is separated and purified by the macroporous resin columns; eluents are mixed solvents with chloroform and methanol when the extract is separated and purified by the silica gel columns; eluents are mixed solvents with methanol or acetonitrile and water when the extract is separated and purified by the reverse phase silica gel columns. The rubiaceae-type cyclopeptide bioside, the method and the applicationhave the advantages that as shown by experimental results obtained by the inventor, the rubiaceae-type cyclopeptide bioside has NF-kB signal pathway inhibitory activity and can be used as an NF-kB signal pathway inhibitor; the rubiaceae-type cyclopeptide bioside is provided with a structure shown as a following formula (I).

The invention discloses a tissue culture rapid propagation technology for morinda officinalis. The morinda officinalis is a rubiaceae plant, can be harvested in the whole year and can be preferably harvested in autumn and winter. The technology comprises the following steps: digging the roots of 5-7 years old morinda officinalis; removing lateral roots; cleaning and drying to 60%-70% dry state; lightly flattening by using a mallet; and drying in sun and cutting into 6-12cm long roots, thereby acquiring an end product. If the end product is steamed for a half hour or is soaked in boiled water,the color is purple and the quality is higher; the roots are in flat cylindrical or net cylindrical shape, are slightly bent and have longitudinal wrinkles and deep sunken horizontal grains; the surface is in dark gray or brown color and is in slight purple color; the texture is tough and the broken section is uneven; the roots are odorless and taste sweet and slightly astringent; and the optimalroots have characterstics of dry stem, toughness, bead string shape, thick pulp and purple color. According to the invention, the morinda officinalis seeds are taken as explants; the morinda officinalis isolated plant is successfully acquired through the processes of callus induction, proliferation, differentiation, rooting, hardening-seedling transplanting, and the like; a tissue culture rapid propagation technical system for morinda officinalis is established; the seed usage in the cultivation production is saved; and the yield of the medicinal material thereof is increased.

The invention relates to a traditional Chinese medicine composition for postpartum recovery. The traditional Chinese medicine composition contains an external washing traditional Chinese medicine andan orally taken traditional Chinese medicine, wherein the external washing traditional Chinese medicine contains hedera helix, rubiaceae uncaria macrophylla, lignum phetimiae, schnabelia oligophylla,honeysuckles, acorus calamus, herba leonuri, fructus gleditsiae, caulis sargentodoxae, lycopodium clavatum, narrowleaf spicebush, Chinese starjasmine stem, ardisiae japonica, lophatherum gracile, herbof ramose scouring rush, folium artemisiae argyi, clinopodium herb, herb of villosulous veronicastrum, plantain herb, root of cream clematis, herb of wooly datchmanspipe, herba lysimachiae, all-grassof straightstalk alpine meadowrue, purple perilla, goldhair hedyotis herb, pericarpium citri reticulatae, glabrousleaf pittosporum leaves, herba pteridis multifidae, serissa foetida comm and caulis akebiae; and the orally taken traditional Chinese medicine contains hedera helix, rubiaceae uncaria macrophylla and fructus gleditsiae. The invention further provides a preparation method and use method of a traditional Chinese medicine composition bag. The traditional Chinese medicine composition can directly act on skin and enter blood through transdermal absorption, and compared with an orally taken medicine, the traditional Chinese medicine composition has the characteristics that the treatment effect is relatively high, the composition is comfortable, the composition does not have any toxic and side effects, and the burden of livers is not increased.

The invention discloses health-care powder capable of reliving eyesight. The health-care powder is prepared from following raw materials in parts by weight: 70-75 parts of soybeans, 60-65 parts of millets, 60-64 parts of corns, 13-16 parts of whole wheat flour, 10-13 parts of taro powder, 4-5 parts of cocoa powder, 5-7 parts of spiral seaweeds, 8-9 parts of black sesames, 3-4 parts of rubiaceae borreria stricta, 8-10 parts of crataegus pinnatifida bunge, 12-13 parts of carrots, 7-9 parts of cactuses, 2-3 parts of a health-care additive and a proper amount of water. The carrots in the health-care powder capable of reliving the eyesight contain abundant sucrose, starch, vitamin A, beta-carotene and the like and the carotene can be converted into the vitamin A in a human body; the vitamin A has very good help on the eyesight of eyes; particularly, the eyesight under dark light and rapidly-changed light can be smoothly finished under the participation of the vitamin A, so as to be good for tonifying liver and improving eyesight and reliving the eye fatigue; and the health of the eyes and the skin can be maintained. Furthermore, the carrots are usually eaten so that the anti-disease capability of the human body can be enhanced and the carrots contain a lot of lignin, the anti-disease capability of a human body is improved and cancers can be reduced and prevented.

The invention discloses noodles capable of balancing viscera. The noodles capable of balancing the viscera are prepared by the following raw materials by weight: 100-110 parts of wheat, 40-50 parts of green beans, 30-40 parts of red beans, 15-20 parts of sesame, 15-20 parts of sunflower seeds, 1-2 parts of tiny ardisia leaves, 2-3 parts of rubiaceae borreria stricta, 1-2 parts of red caustic reeper, 1-2 parts of alpine snow chrysanthemum, 6-8 parts of fresh ginger, 20-30 parts of strawberries, 18-24 parts of swamp cabbages, 20-25 parts of Chinese yam, 25-30 parts of black-bone chicken meat, 1-2 parts of a food modifier and a proper amount of water. The noodles provided by the invention take the wheat, the green beans and the red beans as main raw materials. The green beans has the effects of promoting appetite, reducing blood fat, reducing cholesterol, resisting allergy, detoxifying, clearing heat and removing toxicity, relieving summer heat and restlessness, quenching thirst and invigorating stomach, inducing diuresis to alleviate edema and protecting liver. The red beans has the effects of inducing diuresis to eliminate dampness, activating blood circulation to dispel pus and reducing swelling and resolving toxicity. The fresh ginger has the effects of increasing appetite and invigorating the spleen, promoting the appetite, preventing sunstroke, cooling, refreshing, sterilizing and detoxifying and decreasing swelling to relieve pains. The strawberries have the effects of improving visual acuity and nourishing the liver, replenishing the blood, coordinating intestines and stomach, preventing cancers, beautifying and promoting digestion. The swamp cabbages have the effects of clearing heat, removing toxicity, cooling the blood and inducing the diuresis. The Chinese yam has the effects of strengthening the spleen and stomach, benefiting lung and kidney and tonifying deficiency and weakness. The black-bone chicken meat can invigorate spleen and replenish qi, tonify lung to consolidate exterior and induce the diuresis to reduce edema.

The invention discloses a Chinese medicine preparation for treating chronic periodontitis. Traditional Chinese medical science thinks that inflammation, bleeding, red swelling and pain of gum and ozostomia are mostly caused by stomach fire flaring up, deficiency of the kidney yin and foreign invasion of fire heat, evil and toxicity. Therefore, traditional Chinese medicines such as perny false fairybells rhizome, selenitum, dendrobe, rhizoma anemarrhenae, rubiaceae randia depauperata, golden cypress, meadowrue root and rhizome, souliea vaginata, red peony root, taiwan beautyberry leaf, Indian bodhi tree bark, java speedwell and liquorice are selected in the Chinese medicine preparation disclosed by the invention and decocted for twice by a drug manufacturing room of a hospital (described in the specification) according to the traditional preparation method, filtrates are combined and taken orally, the residual leaves are added with water to be concentrated and decocted, and liquid medicine is leached for rinsing the mouth. Clinical test shows that the total effective rate is 95.6% and is obviously better than that of a control group.

The invention relates to a kind of herbal tea, which is characterized in that the components and the mass percentages of the dry materials of each component are: 10-40% of Gangmeigen, 10-50% of Gardenia, 10-50% of fresh Imperata rhizome, and 10-40% of herbal tea seedlings %, Liuyuexue 5-30%, and the described herbal tea seedling is the root of the Rubiaceae plant Yuyejinhua. A herbal tea with the functions of dispelling wind and relieving exterior, clearing away heat and promoting dampness, relaxing tendons and activating collaterals, relieving summer heat and promoting body fluid, cooling blood and promoting blood circulation. This product has unique taste, stable quality, clear efficacy, safety and convenience, and can adapt to the needs of people of different places and ages at the same time. Fever, dryness and thirst, cure fever, fatigue, insomnia, cough, sore throat, summer-damp diarrhea, acute tonsillitis, pharyngitis, acute and chronic hepatitis and other diseases.

The invention relates to a medicinal fatheadtree extractive, which is extracted from the plate-typed heartwood, branches, trunks, barks or leaves of rubiaceae nauclea medicinal fatheadtree; the obtained medicinal fatheadtree extractive with vincoside-lactam as the principle component can used for preparing the medicines of antisepsis, antivirus, antiphlogosis or anti-hyperthermia. The invention further relates to a medicinal fatheadtree extractive preparation.

The invention discloses a traditional Chinese medicinal composition for treating stages I and II of chronic renal failure. The traditional Chinese medicinal composition in the formula is prepared from the following components in parts by weight: 16 to 20 parts of radix astragali, 17 to 20 parts of radix codonopsis, 6 to 9 parts of parched eucommia ulmoides olive, 7 to 10 parts of herba epimedii, 8 to 9 parts of parched polygonatum sibiricum, 8 to 9 parts of salvia miltiorrhiza, 4 to 6 parts of rubiaceae, 7 to 10 parts of spreading hedyotis herb, 8 to 11 parts of cornus officinalis, 8 to 10 parts of herba leonuri and 3 to 5 parts of divaricate saposhnikovia root. According to the traditional Chinese medicine prepared by a traditional Chinese medicinal formula for treating the stages I and II of the chronic renal failure, the cure rate of the stages I and II of the chronic renal failure is about 20 percent, the obvious effective rate is over 50 percent, and the effective rate is over 90 percent.

The invention provides a rubiaceae-type cyclopeptide compound rubiyunnanin F(8), a pharmaceutical composition with the compound as an active component, as well as a preparation method and application of the compound. The invention provides the preparation method of the compound and application of the compound in preparation of anti-herpes simplex virus type I (HSV-1) medicines.