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60 results about "Habituation" patented technology

Habituation is a form of non-associative learning in which an innate (non-reinforced) response to a stimulus decreases after repeated or prolonged presentations of that stimulus. Responses that habituate include those that involve the intact organism (e.g., full-body startle response) or those that involve only components of the organism (e.g., habituation of neurotransmitter release from in vitro Aplysia sensory neurons). The broad ubiquity of habituation across all biologic phyla has resulted in it being called "the simplest, most universal form of learning...as fundamental a characteristic of life as DNA." Functionally-speaking, by diminishing the response to an inconsequential stimulus, habituation is thought to free-up cognitive resources to other stimuli that are associated with biologically important events (i.e., punishment/reward). For example, organisms may habituate to repeated sudden loud noises when they learn these have no consequences. A progressive decline of a behavior in a habituation procedure may also reflect nonspecific effects such as fatigue, which must be ruled out when the interest is in habituation. Habituation is clinically relevant, as a number of neuropsychiatric conditions, including autism, schizophrenia, migraine, and Tourette's, show reductions in habituation to a variety of stimulus-types both simple (tone) and complex (faces).

Method and device for reflex-based functional gait training

A device and method for gait training, such as for rehabilitation of a person after a stroke is provided. In some embodiments, the device comprises a stimulator, preferably electric stimulator, for provoking a spinal cord withdrawal reflex in the person by stimulation on the person's foot in response to a control signal. Hereby, the person's leg will move and initiate a gait swing. A sensor is placed to sense movement of the leg and provide a feedback signal accordingly. A processor unit with a processor runs a control algorithm which calculates the control signal in response to the feedback signal. Thus, the method is based on a closed-loop design, and the control signal is preferably calculated for each walking step, and it is preferably based on the feedback signal obtained from the preceding walking step. Hereby reflex habituation can be accounted for. Preferably, the stimulator has a plurality of stimulator channels with electrodes placed on different sites distributed on the sole of the foot and on the heel. The feedback signal may be based on accelerometer(s), and / or gyroscope(s), and / or goinometer(s) positioned on the leg and / or foot, e.g. partly or fully integrated in an in-sole for a shoe etc.
Owner:NORDIC NEUROSTIM APS

Variational parameter neurostimulation paradigm for treatment of neurologic disease

The present invention concerns a neural stimulation device, and methods for its use, in which one or more stimulation parameters can be automatically and randomly adjusted such that any particular combination of stimulation parameters is not repeated for a given duration of time, thereby limiting habituation to the neural stimulus.
Owner:UNIV OF FLORIDA RES FOUNDATION INC

Reagent kit for detecting alcoholism and alcohol addiction susceptibility

The invention discloses a reagent box for detecting alcoholic intoxication and susceptibility to alcohol habituation. The reagent box comprises specificity primer pairs and specificity fluorescent probes for detecting position 161 SNP position in ALDH2 gene SEQ ID NO:1, and an ordinary assembly for fluorescent quantitative PCR detection. The reagent box predicts the alcoholic intoxication and susceptibility to alcohol habituation of an individual by detecting and analyzing the gene carried on position SNP on ALDH2 gene.
Owner:XINBAXIANG SHANGHAI MOLECULAR MEDICAL TECH SHANGHAI

Habituation culture method of psychrophilic methanogens

ActiveCN104498422AImprove stabilityRich source of nutritioMicrobiology processesSodium acetateSludge
The invention discloses a habituation culture method of psychrophilic methanogens. The habituation culture method comprises the following steps: 1) feeding a habituation culture medium into a culture device, introducing nitrogen to remove oxygen, sterilizing at high temperature, and adding 0.001g of sodium acetate, sodium formate, methanol, cellulose acetate, chitosan and prebiotics respectively, thereby obtaining a habituation culture device; 2) crushing sludge bacteria, adding activated starch, and putting the mixture to stand, thereby obtaining an activated starch-sludge bacterium; 3) inoculating the bacterium obtained in the step 2) to the habituation culture device of the step 1), and culturing for 4-5 days at 8 DEG C; 4) detecting, changing the temperature through a temperature control system when bubbles are generated, and implementing temperature-variable habituation culture; and 5) stopping temperature variation when the bubbles are not increased any more, and replenishing materials to generate bubbles continuously until the gas generation amount is completely stable after 12 days, thereby completing enrichment of psychrophilic methanogens. By adopting the habituation culture method of psychrophilic methanogens, the formation speed of bacterial colonies is remarkably increased, and the enrichment effect is improved.
Owner:GANSU DEFU BIOTECH
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