946 results about "Tinnitus" patented technology

The present invention relates to a method for computer-controlled modelling of customised earpieces. These earpieces include housings for hearing aids, wireless or connected communication devices (headsets, mobile phones, personal agents), loud speakers, tinnitus masking devices, devices recording vibrations in the skull and transforming these into audio signals, voice recognition devices, earplugs, noise blockers with selective frequencies or sound levels, Man Machine Interface (MMI) products that enable clear communication even in the noisiest environments, or products related to wireless Internet applications. All these earpieces may be worn in the user's meatus and / or auditory canal. The invention also relates to a computerised system for manufacturing such customised earpieces. In particular, the invention is directed to a computerised system that models an earpiece based on a three-dimensional replica of the user's meatus and / or auditory canal.

The invention comprises a totally implantable hearing prosthesis for hearing impaired persons. An inertial vibrational element is hermetically sealed and implanted in bone between the lateral and superior semicircular canals without breaching the integrity of the canals. The vibrational element is adapted to vibrate the walls of the canals and the fluids contained therein, thereby vibrating contiguous fluids within the cochlea thus stimulating hair cells and creating a hearing percept. The invention can also be adapted to be a tinnitus masking system, and / or used in combination with a coehlear implant hearing system.

Disclosed is a method of treating small intestinal bacterial overgrowth (SIBO) or a SIBO-caused condition in a human subject. SIBO-caused conditions include irritable bowel syndrome, fibromyalgia, chronic pelvic pain syndrome, chronic fatigue syndrome, depression, impaired mentation, impaired memory, halitosis, tinnitus, sugar craving, autism, attention deficit / hyperactivity disorder, drug sensitivity, an autoimmune disease, and Crohn's disease. Also disclosed are a method of screening for the abnormally likely presence of SIBO in a human subject and a method of detecting SIBO in a human subject. A method of determining the relative severity of SIBO or a SIBO-caused condition in a human subject, in whom small intestinal bacterial overgrowth (SIBO) has been detected, is also disclosed.

A tinnitus masking system for use by a person having tinnitus The system comprises a sound delivery system having left and right ear-level audio delivery devices and is configured to deliver a masking sound to the person via the audio delivery devices such that the masking sound appears to originate from a virtual sound source location that substantially corresponds to the spatial location in 3D auditory space of the source of the tinnitus as perceived by the person. The masking sound being represented by left and right audio signals that are converted to audible sound by the respective audio delivery devices.

A tinnitus method and device for providing relief to a person suffering from the disturbing effects of tinnitus is described. The method can be implemented entirely in software to spectrally modify an audio signal in accordance with a predetermined masking algorithm which modifies the intensity of the audio signal at selected frequencies. A predetermined masking algorithm is described which provides intermittent masking of the tinnitus wherein, at a comfortable listening level, during peaks of the audio signal the tinnitus is completely obscured, whereas during troughs the perception of the tinnitus occasionally emerges. In practice it has been found that such intermittent masking provides an immediate sense of relief, control and relaxation for the person, whilst enabling sufficient perception of the tinnitus for habituation and long term treatment to occur. Advantageously the predetermined masking algorithm is specifically tailored to the audiometric configuration of the person. For example, the masking algorithm may be partly tailored to the hearing loss characteristic of the person. A tinnitus rehabilitation device used in conjunction with a personal sound reproducing system is also described.

A tinnitus method and device for providing relief to a person suffering from the disturbing effects of tinnitus is described. The method can be implemented entirely in software to spectrally modify an audio signal in accordance with a predetermined masking algorithm which modifies the intensity of the audio signal at selected frequencies. A predetermined masking algorithm is described which provides intermittent masking of the tinnitus wherein, at a comfortable listening level, during peaks of the audio signal the tinnitus is completely obscured, whereas during troughs the perception of the tinnitus occasionally emerges. In practice it has been found that such intermittent masking provides an immediate sense of relief, control and relaxation for the person, whilst enabling sufficient perception of the tinnitus for habituation and long term treatment to occur. Advantageously the predetermined masking algorithm is specifically tailored to the audiometric configuration of the person. For example, the masking algorithm may be partly tailored to the hearing loss characteristic of the person. A tinnitus rehabilitation device used in conjunction with a personal sound reproducing system is also described.

A method and system for providing rectangular and / or complex electrical pulses to cortical tissues of a patient for providing therapy or alleviating symptoms for at least one of tinnitus, essential tremor (ET) including Parkinson's disease, depression, or for providing improvement of functional recovery following stroke. The intracranial electrodes may be implanted on the dura, or subdurally on the pia mater of the cortical surface. The placement of the electrodes may utilize cortical sensing and / or digital imaging techniques, such as fMRI, MRI, or CT. The pulse generator system comprises implantable and external components. The pulse generator may be an implanted pulse generator (IPG) or an external stimulator coupled with an implanted stimulus-receiver. The IPG may also comprise a rechargeable battery. In one embodiment the pulse generator may also comprise a selected number of predetermined / pre-packaged programs. In one embodiment, the pulse generation may also comprise telemetry means, for remote interrogation and / or programming of said pulse generator utilizing a wide area network, such as the internet.

A tinnitus method and device for providing relief to a person suffering from the disturbing effects of tinnitus is described. The method can be implemented entirely in software to spectrally modify an audio signal in accordance with a predetermined masking algorithm which modifies the intensity of the audio signal at selected frequencies. A predetermined masking algorithm is described which provides intermittent masking of the tinnitus wherein, at a comfortable listening level, during peaks of the audio signal the tinnitus is completely obscured, whereas during troughs the perception of the tinnitus occasionally emerges. In practice it has been found that such intermittent masking provides an immediate sense of relief, control and relaxation for the person, whilst enabling sufficient perception of the tinnitus for habituation and long term treatment to occur. Advantageously the predetermined masking algorithm is specifically tailored to the audiometric configuration of the person. For example, the masking algorithm may be partly tailored to the hearing loss characteristic of the person. A tinnitus rehabilitation device used in conjunction with a personal sound reproducing system is also described.

The disclosure relates to jointly transmitting and processing analog-digital information using Inaudible Synchronous Online User-optimized Processing (iSOUP), wherein digital and analog information can be transmitted via one connection. iSOUP may be implemented in real-time MP3 anti-piracy, customized MP3 songs, Internet customized medical devices, Internet customized consumer electronics, Internet controlled psychoacoustic and physiological tests, tinnitus treatment devices, anti-piracy MP3 players, assistive listening MP3 players, healthcare sensor networks, Bluetooth sensors, audio-visual hearing aids (HAs) and cochlear implants (CIs), audio-touch HAs and CIs, Bluetooth HAs and CIs, automated fitting of HAs and CIs. The invention has applicability in copyright protection, data hiding, hearing aid remote controls, children learning devices, musical special effects generators, multiuser multimedia devices, Internet treatment and disease surveillance, wireless medical devices, wireless telemetry, multimedia rehabilitation devices, hearing aids and other implants.

The present invention relates to a method for computer-controlled modelling of customised earpieces. These earpieces include housings for hearing aids, wireless or connected communication devices (headsets, mobile phones, personal agents), loud speakers, tinnitus masking devices, devices recording vibrations in the skull and transforming these into audio signals, voice recognition devices, earplugs, noise blockers with selective frequencies or sound levels, Man Machine Interface (MMI) products that enable clear communication even in the noisiest environments, or products related to wireless Internet applications. All these earpieces may be worn in the user's meatus and / or auditory canal. The invention also relates to a computerised system for manufacturing such customised earpieces. In particular, the invention is directed to a computerised system that models an earpiece based on a three-dimensional replica of the user's meatus and / or auditory canal.

The invention comprises a totally implantable hearing prosthesis for hearing impaired persons. An inertial vibrational element is hermetically sealed and implanted in bone between the lateral and superior semicircular canals without breaching the integrity of the canals. The vibrational element is adapted to vibrate the walls of the canals and the fluids contained therein, thereby vibrating contiguous fluids within the cochlea thus stimulating hair cells and creating a hearing percept. The invention can also be adapted to be a tinnitus masking system, and / or used in combination with a cochlear implant hearing system.

Tinnitus masking systems for treating tinnitus are described where a device is coupled to a surface of a bone or to a tooth or several teeth. Such a device may comprise an oral appliance having an electronic and / or transducer assembly for generating sounds via a vibrating transducer element. Generally, the transducer may generate one or more frequencies of sound via the actuatable transducer to transmit a modified audio signal via vibratory conductance to an inner ear of the patient to mask tinnitus during a peak of the audio signal and to allow the user to perceive the tinnitus during a trough of the audio signal. The audio signal is also modified to account for any hearing loss of the patient as well as a bone conductance profile measured from the patient.

The invention defines interdependent biofactors and biomolecules, and clinically useful formulations that are comprised of them. The active agents are demonstrated to be complementary in their physiologic functions especially as these relate to the quenching of free radicals and to the support of endothelial physiology, the reduction of hyperinsulinemia and improvements in vascular health. The active components of the invention are selected for inclusion in precise combinations specifically because they improve these various conditions and physiological functions, and by so doing reduce a variety of risks associated with hearing loss and tinnitus. The resulting enhancement of general systemic vascular health, improvement in local VIIIth nerve vascular health, modulation of conditions surrounding blood fluid dynamics, the consequences of hyperinsulinemia, and improvements in free radical defenses, all reduce the potential for cochlear hair cell death and VIIIth nerve atrophy, and the hearing loss and possible deafness that accompany them.

A method for treating severe tinnitus is disclosed. The method of the present invention comprises implanting a catheter into a patient and administering a drug formulation or fluid comprising a therapeutic agent intrathecally into the patient's cerebrospinal fluid.

Electrical stimulation is applied to the inferior colliculus or colliculi (IC), in order to diminish tinnitus by revising auditory pathway neuronal activity. This intervention diminishes tinnitus and treats other neurological and otological disorders. The locations and methods of electrode placement and anchoring and the structure of the electrodes are an advance over prior treatments. Other treatment locations in the nearby region of the IC, including the superior colliculi (SC) and Peri-aqueductal gray (PAG), provide treatments for other disorders and symptoms such as partial hearing loss and pain. The IC is a unique choice for the treatment of tinnitus and other disorders because an electrode placed in that region enables minimal invasiveness. The anchoring location also uniquely minimizes invasiveness by providing the option of residing in the meninges instead of the brain tissue. The shape of the electrode and its anchoring process uniquely match the brain's anatomy in order to provide greater specificity in diagnosis and treatment. Stimulation of areas near the IC, particularly the superior colliculus and peri-aqueductal gray, can be used to treat various neurological disorders. Customized feedback from the implantable system enables the creation of customized treatment programs.

The invention relates to a tinnitus hearing aid which comprises a tinnitus masking module and a hearing compensation module, and is characterized in that the tinnitus hearing aid further comprises a control module; the control module comprises a pre-setting unit, a selecting unit and a voice classification device; the pre-setting unit is used for selecting any one function mode in tinnitus masking, hearing compensation and tinnitus masking and hearing compensation, and inputting related preset parameters; the voice classification device is used for sequentially performing pre-treatment, feature extraction and classification according to received signals, and finally determining a sound field environment; a signal processing algorithm is selected and the parameters in the signal processingalgorithm are adjusted according to the function mode selected by the pre-setting unit and the determined sound field environment, and optimal combination is further performed; and the selecting unitis used for opening the voice classification device and working according to the function mode selected by the pre-setting unit.

A system and method for adaptive therapeutic intervention to effect real-time changes in the behavioral profile of an individual to facilitate the effectiveness of combined bioelectric sensing and biosensory based therapy for specific disorders. The system and method induces a temporary physiological state-of-mind (e.g., increased relaxation) to effect persistent changes to the cognitive-emotive profile of the individual (e.g., reduce internal tinnitus). The sense- and mental state-awareness responses, integrated into a two-way (i.e., bi-directional) feedback system using a dynamic interface with intelligently controlled thresholds. The invention takes into account details of multi-variate and nonlinear dynamics and database templates to more accurately compute the user's “state-of-mind.” It then utilizes this “state-of-mind” to drive therapeutic and non-therapeutic stimulus intervention. By way of a “combinatorial stimulation sequence” approach that uses customized sounds, the present invention creates a fine-tuned and well-controlled process. The significance of this interactivity is a prolonged change in the individual's cognitive-emotive profile.

Methods and systems for treating tinnitus are provided. Some embodiments include a method of providing a primary audio signal having a primary peak portion substantially centered at about a tinnitus frequency of a patient. The method may also include combining the primary audio signal with a general audio signal to generate a combined sound. The method may also include exposing the patient to the combined sound so that the patient hears the combined sound, to diminish a perception by the patient of tinnitus.

The invention provides a sleep-improving and health-care drug pillow, relating to a health-care medical product, in particular to making materials and process of the sleep-improving and health-care drug pillow. A drug core of the pillow mainly comprises the following raw materials in parts by weight: 1000 parts of cottonseeds, 500 parts of buckwheat shell, 20 parts of tea, 30 parts of spina date seed, 30 parts of schisandra, 20 parts of lily, 20 parts of ganoderma lucidum, 30 parts of akebia stem, 30 parts of tuber fleeceflower root, 10 parts of cordyceps, 10 parts of Chinese angelica, 30 parts of rehmannia root, 10 parts of safflower, 30 parts of red-rooted salvia root, 10 parts of longan, 30 parts of common clubmoss herb, 30 parts of garden balsam stem, 10 parts of Chinese atractylode rhizome, 10 parts of clematis root, 30 parts of pawpaw, 30 parts of divaricate saposhnikovia root, 30 parts of dried orange peel, 20 parts of costustoot, 20 parts of polygala root, 30 parts of Szechwan lovage rhizome, 10 parts of honeysuckle, 20 parts of glossy privet fruit, 10 parts of wild chrysanthemum, 10 parts of lonicera chrysantha flower, 10 parts of amomum shell, 20 parts of mint, 30 parts of galanga, 20 parts of bergamot, 20 parts of coptis, 20 parts of amur corktree bark, 10 parts of tuber fleeceflower stem, 10 parts of dwarf lilytruf tuber, 10 parts of dandelion, 30 parts of radix astragali, 30 parts of nutgrass galingale rhizome, 2000 parts of millet mature vinegar, 30 parts of honey and 30 parts of yellow wine and is refined by adopting the processes of soaking, roasting, brewing, mixing and the like. The sleeping-improving and health-care pillow has the advantages of simple making process and strong drug efficacy and has special curative effects on long-term insomnia, high blood pressure, headache, tinnitus and cervical pain.

The invention defines interdependent biofactors and biomolecules, and clinically useful formulations that are comprised of them. The active agents are demonstrated to be complementary in their physiologic functions especially as these relate to the quenching of free radicals and to the support of endothelial physiology, the reduction of hyperinsulinemia and improvements in vascular health. The active components of the invention are selected for inclusion in precise combinations specifically because they improve these various conditions and physiological functions, and by so doing reduce a variety of risks associated with hearing loss and tinnitus. The resulting enhancement of general systemic vascular health, improvement in local VIIIth nerve vascular health, modulation of conditions surrounding blood fluid dynamics, the consequences of hyperinsulinemia, and improvements in free radical defenses, all reduce the potential for cochlear hair cell death and VIIIth nerve atrophy, and the hearing loss and possible deafness that accompany them.

The present description relates to cranial nerve stimulation to treat a neurological disorder. More particularly, and not by way of limitation, the present invention is directed to a system and method for stimulating a cranial nerve to treat a neurological disorder, such as tinnitus or an anxiety disorder.

Provided herein are 3,3-disubstituted 19-nor-steroidal compounds according to Formula (I): and pharmaceutical compositions thereof. Such compounds are contemplated useful for the prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, schizophrenia spectrum disorders, disorders of memory and / or cognition, movement disorders, personality disorders, autism spectrum disorders, pain, traumatic brain injury, vascular diseases, substance abuse disorders and / or withdrawal syndromes, tinnitus, and status epilepticus.

An apparatus, software, procedures and technology that, beginning with a simple manipulative auditory paradigm, moves up the auditory neural pathways, modifying the basic stimulus from a unilateral routine audiology tool to a dichotic central auditory processing diagnostic tool that defines hearing loss along the entire auditory chain from the middle ear to the cortex. From the resultant data comes information related to the reduction of tinnitus employing parathreshold central procedures rather than the traditional suprathreshold masking or phase-shifting techniques. The new application modifies and applies known technology in new ways for both the top-down and bottom-up differential diagnosis of auditory disorders and the tinnitus reduction.

Gastric retentive dosage forms for sustained release of acamprosate are described which may allow once- or twice-daily dosing for both acute and long-term treatment of a disorder including alcohol dependence, tinnitus, sleep apnea, Parkinson's disease, levodopa-induced dyskinesias in Parkinson's disease, Alzheimer's disease, Huntington's disease, Amyotrophic lateral sclerosis, Cortical spreading depression, migraine, schizophrenia, anxiety, tardive dyskinesia, spasticity, multiple sclerosis, various types pain, or binge eating. Methods of treatment using the dosage forms and methods of making the dosage forms are also described.

A hearing aid (62, 72, 82, 92, 102, 112) adapted for alleviating tinnitus of a user (75), comprises an audio input means (83), a signal processing unit (88, 98, 108, 118) and an output transducer (80). The hearing aid further comprises a band stop filter (87) arranged to match a tinnitus of the user and switching means (86, 116) and switch control means (84, 114) for controlling the switching of said band stop filter (87) into and out of the signal path between the audio input means (83) and the output transducer (80), in response to a predefined trigger event. The invention further provides a method of adjusting a hearing aid.

Compositions, and methods of use thereof, are provided for the prevention, treatment or alleviation of symptoms of hearing are provided. Embodiments of the methods employ zonisamide as the sole active pharmaceutical agent or a combination of zonisamide and another pharmaceutical agent, such as an antioxidant, a NMDA antagonist, an SSRI or a combined SSRI / NMDA antagonist agent. Other embodiments of the method involve the use of zonisamide alone or in combination with another API to prevent, treat or ameliorate one or more symptoms of hearing loss. Hearing disorders treatable with the invention include noise-induced hearing loss, drug-induced hearing loss, central auditory hearing disorder (CAPD), tinnitus and presbyacusis.

Methods and systems for tinnitus treatment are described where a device is coupled to a surface of a bone or to a tooth or several teeth. Such a device may comprise an oral appliance having an electronic and / or transducer assembly for generating sounds via a vibrating transducer element. Generally, the transducer may be programmed to adjust any number of settings and treatment options to generate one or more frequencies of sound via the actuatable transducer to transmit a modified audio signal via vibratory conductance to an inner ear of the patient to mask the tinnitus. The audio signal is also modified to account for any hearing loss of the patient as well as a bone sensitivity threshold measured from the patient and calibrated by the programming device.

The invention discloses dried tofu with soybeans as main ingredients. The dried tofu comprises the following raw materials in parts by weight: 100-106 parts of soybeans, 6-10 parts of corn kernels, 4-6 parts of seasame, 6-10 parts of buckwheat, 2-3 parts of pseudo-ginseng, 1-2 parts of lily, 1-2 parts of schisandra chinensis, 1-2 parts of pollen pini, 1-2 parts of Chinese chives, 2-4 parts of garlic bolt, 2-7 parts of white sugar, 2-6 parts of salt, 0.5-1 part of Chinese hawthorn seed powder, a proper amount of mulberry and 0.03-0.06 part of bean product defoaming agent. The dried tofu prepared by the invention has rich nutrition and good taste; the plurality of powder agent added before squeezing and the method of using the mulberry as flavor modifier provide high health protection value to the product; the mulberry can be used for treating dizziness caused by deficiency of liver and kidney, blood deficiency and essence deficiency, waist soreness and tinnitus, premature graying of hair, insomnia and dreaminess, fluid impairment and thirst, consumptive thirst and constipation due to intestinal dryness; and the schisandra chinensis can treat cough and asthma due to lung deficiency, thirty, spontaneous perspiration, night sweat, thinness and weakness due to overexertion, wet dream, spermatorrhea and lingering dysentery.