354 results about "Treatment options" patented technology

A comprehensive healthcare analytic and predicative modeling system that tracks costs for patients on a long term basis (greater than 6 months, one-year, or more) to assess the long-term effectiveness of various treatment options. Based upon the evaluation of the long-term effectiveness of various treatment options, the system then delivers a predictive model, which is based on data extracted and aggregated from dissimilar databases, that analyzes up-to-date economic and clinical outcomes, and then, using this data, can estimate long-term future treatment results from an economic and clinical perspective. Also disclosed herein is a personal electronic medical record on a computer network created by a medical provider on the authorization of the patient and controlled by the patient. Lastly, disclosed herein is a computer system for the consolidation of medical and financial data from disparate databases into a unitary data format.

An efficient, objective, flexible and easily deployable system for conducting evaluations of mental and physiological state and recommending individualized treatment to improve said state is described. The method and system are based on commensurate measurement of mental functions, levels of stress and anxiety, and / or biologically active molecules such as neurotransmitters, immune markers including cytokines and hormones. The method and system are designed to assess an individual's cognitive function and the underlying physiology in order to delineate various disease processes, injuries, drug states, training stages, fatigue levels, stress levels, aging processes, predict susceptibility to stress and / or sleep deprivation, identify aptitude for training and / or characterize effects of any experimental conditions. The system and method may be used in recommending individualized treatment protocols, as well as to guide the treatment process by assessing the efficacy of such therapies in the clinical trials process.

A patient's dentition is analysed to determine an orthodontic treatment plan by simulating an intervention in advance. 3D imaging techniques and computer technology are used to simulate and predict tooth movement as a function of the chosen treatment, i.e. a specific orthodontic appliance. In this way treatment options can be compared and the most optimal (shortest treatment time, lowest forces . . . ) treatment for each individual patient can be selected. Sub-steps of the tooth movement are not predefined but computed based on a simulation of orthodontic elements and wire as they would be used in the orthodontic treatment of the patient. This means that the sub-steps are calculated based on the relationship between the applied loads and the tooth movement; only one of both parameters can be chosen freely. Thus, either the tooth load is specified and applied in order to calculate the resulting tooth movement or vice versa the tooth movement is specified and applied in order to calculate the tooth load that should be applied. Moreover, the current invention allows predicting the time at which brackets and / or archwire should be changed, and comparing different treatment options with respect to tooth loading and duration.

The present invention relates to a methodology for the conversion of unstructured, free text data (contained within medical reports) into standardized, structured data, and also relates to a decision support feature for use in diagnosis and treatment options.

A mobility assessment detects abnormalities in motion using a stagger algorithm. The detected abnormalities are compared to known norms for a particular test to determine if the abnormalities are normal or not. The comparison can be made for abnormalities associated with different diseases and illnesses to classify whether or not the condition exists and its phase. The results may be used to generate a treatment regime.

A therapeutic pad system (200) is disclosed for the treatment of edema, wherein the pressure applied to the user by the pad encourages the proximal flow of lymph. A fluid is provided to one or more bladder-type pads (220) in the pad through an inlet port (218) at a distal end of the pad, and is expelled from the bladder through an outlet port (220) at the proximal end of the bladder, thereby producing a pressure gradient across the pad. The system includes a flexible and compressible liner (250) filled with a number of small foam pieces (258) that is adapted to be wrapped about the therapeutic pad, and a relatively rugged, outer binder (270) that is securable about the liner (250). An advantage of the present system is that it may be applied in a number of different modes and combinations providing many treatment options.

An automated method for determining prognosis based on an analysis of abnormality (lesion) features and parenchymal features obtained from medical image data of a patient. The techniques include segmentation of lesions from radiographic images, extraction of lesion features, and a merging of the features (with and without clinical information) to yield as estimate of the prognosis for the specific case. An example is given for the prognosis of breast cancer lesions using mammographic data. A computerized image analysis system for assessing prognosis combines the computerized analysis of medical images of cancerous lesions with the training-based methods of assessing prognosis of a patient, using indicators such as lymph node involvement, presence of metastatic disease, local recurrence, and / or death. It is expected that use of such a system to assess the severity of the disease will aid in improved decision-making regarding treatment options.

The subject invention provides methods for evaluating women in designing appropriate menopausal and postmenopausal therapies to match the particular needs of the individual. In one embodiment, the subject invention provides methods for evaluating particular factors in menopausal and postmenopausal women that are then taken into account in identifying a therapy program to promote good health and reduce the risk of any adverse health effects as a result of the therapy, specifically the role of hormone induced / associated breast cancer. More specifically, the subject invention includes methods for evaluating menopausal and postmenopausal women to determine whether hormone replacement therapy is appropriate in this regard, and if so, the specifics of how that therapy is to be administered. The subject invention, by incorporating various factors into a comprehensive, function breast hormone profile, allows for the identification of untreated women with estrogen-related metabolic abnormalities that may increase the risk of breast cancer. The subject invention determines specific therapies to correct and / or inhibit the aberrant biosynthetic pathways, and thus, the risk of cancer.

A system and method are provided for significantly reducing or substantially eliminating angular geometric distortions in devices designed for imaging and / or inspection of an interior portion or surface of a cavity. A series of processing steps or methods may be employed to eliminate Non-Uniform Rotational Distortion (NURD) in such devices, for example, unidirectional and bi-directional intravascular ultrasonic (IVUS) imaging systems. The system may include a processor and an electronic module which control operation of a transducer assembly provided at a distal end of a catheter assembly. The system invokes a first processing step or method to collect and store raw angle and line data, as well as one or more of second and third processing steps or methods which adjust for NURD experienced during backlash of a bi-directional imaging system and a fourth processing step or method which performs a line-to-line correlation function. The system and method provide more accurate and reliable angular orientations of anomalies identified during imaging and / or inspection of the interior portion or surface of the cavity, thus facilitating diagnosis and treatment options.

Methods for classifying and for evaluating the prognosis of a subject having breast cancer are provided. The methods include prediction of breast cancer subtype using a supervised algorithm trained to stratify subjects on the basis of breast cancer intrinsic subtype. The prediction model is based on the gene expression profile of the intrinsic genes listed in Table 1. This prediction model can be used to accurately predict the intrinsic subtype of a subject diagnosed with or suspected of having breast cancer. Further provided are compositions and methods for predicting outcome or response to therapy of a subject diagnosed with or suspected of having breast cancer. These methods are useful for guiding or determining treatment options for a subject afflicted with breast cancer. Methods of the invention further include means for evaluating gene expression profiles, including microarrays and quantitative polymerase chain reaction assays, as well as kits comprising reagents for practicing the methods of the invention.

A system and method for interactively selecting call treatment in real time for an incoming call in a radio telecommunications network. A modified mobile station includes a display, a browser application that presents call information regarding the incoming call and call-treatment options on a pop-up menu the display, a keypad for a user to select a call-treatment option, and a Client Access Function Teleservice (CATS) handler that packages the selected call-treatment option in an IS-136 R-DATA message and sends the R-DATA message to a modified mobile switching center (MSC). The MSC determines that the R-DATA message is a CATS message from the value of the Higher Layer Protocol Identifier (HLPI) in the R-DATA message, and sends the call-treatment option to a modified service node in a short message service (SMS) message. A server in the service node receives the SMS message from the MSC, extracts the selected call-treatment option, and translates the call-treatment option into service scripts understood by the service node.

A method and apparatus for stimulation of a baroreflex system of a patient is provided. A method comprises establishing a therapy regimen including at least one pulse which includes at least two phases. Each phase has a polarity which is different than that of the other phase. The baroreflex system of the patient is activated with at least one baroreflex activation device which is responsive to the therapy regimen.

A method and system for automated decision support for treatment planning of arterial stenoses is disclosed. A set of stenotic lesions is identified in a patient's coronary arteries from medical image data of the patient. A plurality of treatment options are generated for the set of stenotic lesions, wherein each of the plurality of treatment options corresponds to a stenting configuration in which one or more of the stenotic lesions are stented. For each of the plurality of treatment options, predicted hemodynamic metrics for the set of stenotic lesions resulting from the stenting configuration corresponding to that treatment option are calculated.

A patient treatment method is provided. In one embodiment, the method includes inputting physiological data of a patient into a computer model that is configured to simulate a physiological activity of the patient. The method may also include operating the computer model for each of a plurality of potential treatment options to generate a plurality of personalized modeled results based at least in part on simulated effects of each potential treatment option on the physiological activity. Additionally, the method may include selecting an optimal treatment option from the plurality of potential treatment options based at least in part on the plurality of personalized modeled results, developing a personalized treatment plan comprising the optimal treatment option, and treating the patient based at least in part on the personalized treatment plan. Other methods, systems, and computer-readable media are also disclosed.

A mobility assessment detects abnormalities in motion using a stagger algorithm. The detected abnormalities are compared to known norms for a particular test to determine if the abnormalities are normal or not. The comparison can be made for abnormalities associated with different diseases and illnesses to classify whether or not the condition exists and its phase. The results may be used to generate a treatment regime.

A medical accelerator system is provided for simultaneous radiation therapy to all treatment fields. It provides the single dose effect of radiation on cell survival. It eliminates the inter-field interrupted, subfractionated fractionated radiation therapy. Single or four beams S-band, C-band or X-band accelerators are connected to treatment heads through connecting beam lines. It is placed in a radiation shielding vault which minimizes the leakage and scattered radiation and the size and weight of the treatment head. In one version, treatment heads are arranged circularly and connected with the beam line. In another version, a pair of treatment heads is mounted to each ends of narrow gantries and multiple such treatment heads mounted gantries are assembled together. Electron beam is steered to all the treatment heads simultaneously to treat all the fields simultaneously. Radiating beam's intensity in a treatment field is modulated with combined divergent and pencil beam, selective beam's energy, dose rate and weight and not with MLC and similar devices. Since all the treatment fields are treated simultaneously the dose rate at the tumor site is the sum of each of the converging beam's dose rate at depth. It represents the biological dose rate. The dose rate at d-max for a given field is the individual machine dose rate. Its treatment options includes divergent or pencil beam modes. It enables to treat a tumor with lesser radiation toxicities to normal tissue and higher tumor cure and control.

A pain measurement and diagnostic system (PMD) for bioanalytical analysis of pain matrix activity and the autonomic nervous system to diagnose and validate patient treatments, health status and outcomes. The PMD is implemented using medical devices for measuring and reporting objective measurements of pain through patient monitoring and analyzing related biological, psychological, social, environmental, and demographic factors that may contribute to and effect physiological outcomes for patients and through the integrated and iterative analysis improve diagnosis of pain, the evaluation of related disease states, health status, and treatment options.

A system and method for ‘Individualized Life Management’ focusing on individualized and collaborative health care involving a plurality of individuals, using groups of state parameters for defining a state of each individual, and using groups of action parameters for defining ‘treatment options’ and / or ‘behavior options’ targeted at an individual. The system includes a data processor for processing input data, which are based on the groups of state parameters, into output data, which are the basis for the groups of action parameters, using defined relationships / assignments between groups of state parameters and groups of action parameters. Data storage stores the groups of state parameters and action parameters and the defined relationships / assignments between groups of the state and action parameters. A data communication system / platform communicates state parameters and / or action parameters among the individuals. The data processor means can include an adaptive structure (e.g., neural networks) where the defined relationships / assignments between groups are redefined / updated using empirical pairs of action parameter groups and state parameter groups.

The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF). The methods provide for efficiently removing target compounds from CSF. The systems provide for a multilumen flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and / or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and / or removal of targeted therapeutic agents. The invention finds use as a diagnostic, therapeutic and drug delivery platform for a variety of diseases affecting the CNS by accessing the CSF space. Exemplified disease conditions treatable by the present CSF processing systems and methods include, but are not limited to: Cerebral Vasospasm, Guillain Bane Syndrome, illustrating multi-lumen lumbar approach Alzheimer's, Parkinson's, Huntington's, Multiple Sclerosis, Amyotrophic Lateral Sclerosis, Spinal Cord Injury, Traumatic Brain Injury, Stroke, Cancer affecting the brain or spinal cord, Prion disease, Encephalitis from various causes, Meningitis from various causes, diseases secondary to enzymatic or metabolic imbalances, Biological Warfare, etc. For the first time, the present invention offers patients a disease-modifying, disruptive technology treatment platform that addresses the known disease pathogenesis of a number of neurologic conditions to which there are presently limited and ineffective treatment options.

Service subscriber inbound call control is effected from within a public switched telephone network (PSTN) using a Call Service Node (CSN). On receipt of a call directed to the service subscriber, at least one messaging network message is sent to the service subscriber to request a call treatment option. Pending receipt of a reply from the subscriber, the call is routed by the CSN to a call parking facility in the PSTN. The call parking facility may be a voice mail box of the subscriber or an announcement facility. After a call treatment option is received, the call is released from the call parking facility the call treatment is effected. The service enables single number service for multiple service subscriber directory numbers, unified voice mail for multiple service subscriber telephone numbers, or segregated voice mail boxes for a single service subscriber number, as well as real-time, interactive inbound call screening.

Systems and methods are described herein for disease knowledge modeling and clinical treatment decision support, and the prioritization of possible treatment options based on tumor or other disease biomarkers. Disease or indication information, including identification of biomolecular entities associated with the indication may be culled through text data mining to create a knowledge model of the indication. In some embodiments, the knowledge model may comprise a network of associations between molecular entities, including such drug targets and biomakers, genes, pathways. The model may be combined with patient-specific variant information and historical treatment records to identify and prioritize treatment decisions and allow for the prediction of disease drivers and provide treatment options tailored to a patient's genetic data.

A simplified insulin pump allows type II diabetics to identify routine patterns in their daily lifestyle that provide a generally accurate typical pattern of activity and meals. An infusion regimen can be programmed into the pump that generally correlates with this typical pattern to provide a viable treatment option for a type II diabetic without the need for specific and precise matching of insulin to carbohydrate consumption or activity level.

An apparatus, system, and method are disclosed for determining a patient's condition. A system for determining a patient's condition, in one embodiment, comprises a computer processor device, an interface between the computer processor and one or more patient monitoring devices, and a software program configured to interpret patient input data, diagnose the patient's condition, and recommend treatment options. A method for determining a patient's condition may comprise receiving patient data from one or more patient monitoring devices, consulting a treatment database, determining a diagnosis, and converting a diagnosis into a treatment.

A therapeutic pad system (200) is disclosed for the treatment of edema, wherein the pressure applied to the user by the pad encourages the proximal flow of lymph. A fluid is provided to one or more bladder-type pads (220) in the pad through an inlet port (218) at a distal end of the pad, and is expelled from the bladder through an outlet port (220) at the proximal end of the bladder, thereby producing a pressure gradient across the pad. The system includes a flexible and compressible liner (250) filled with a number of small foam pieces (258) that is adapted to be wrapped about the therapeutic pad, and a relatively rugged, outer binder (270) that is securable about the liner (250). An advantage of the present system is that it may be applied in a number of different modes and combinations providing many treatment options.

Method, system, and computer program product for visualization of patient treatments are provided. The method includes: selecting a patient; retrieving data records of patients with similar conditions requiring treatment to the selected patient; and building a tree structure for display with nodes of treatment options and a temporal axis showing treatment results of the similar patients. The tree structure includes representing side effects of a treatment option at a node including a visualization of the strength of the side effect. The tree structure also includes providing edges between the nodes representing a length to progression of the condition requiring treatment.

An apparatus and method used for medical and / or cosmetic treatment of a tissue, such as skin tightening, skin laxity and / or wrinkle reduction and or other skin flaws, including an energy source, a vacuum chamber and rollers which may facilitate easy sliding of the apparatus from one treated area to another. The rollers may also prevent excessive friction of the skin during the treatment. The energy source can be configured to emit energy based on the position of the apparatus on the skin (i.e., the position of the rollers), as well as the pressure within the vacuum chamber. The vacuum level and energy emission can be changed or pulsed based on the treatment regime.

A system enables a healthcare organization to evaluate cost efficient treatment options early in a patient treatment process by automatic monitoring of profit or loss of a treatment, in real-time and enables a clinical user to screen, simulate and control treatment profit or loss during a patient visit, based on both expected reimbursement and the actual costs of performed services. A system enables cost based treatment selection by providing a healthcare worker with patient specific treatment cost information during a treatment episode. An acquisition processor automatically interrogates at least one information repository for data concerning cost to a healthcare organization of providing a proposed treatment to a patient and expected cost reimbursement to the healthcare organization for the proposed treatment. The acquisition processor initiates generation of at least one message including a patient identifier and treatment identification code for communication to the at least one information repository, in response to data indicating occurrence of a treatment related event. A display processor initiates generation of data representing at least one display image including information indicating the proposed treatment is unprofitable for the healthcare organization.

Systems and methods are disclosed for evaluating cardiovascular treatment options for a patient. One method includes creating a three-dimensional model representing a portion of the patient's heart based on patient-specific data regarding a geometry of the patient's heart or vasculature; and for a plurality of treatment options for the patient's heart or vasculature, modifying at least one of the three-dimensional model and a reduced order model based on the three-dimensional model. The method also includes determining, for each of the plurality of treatment options, a value of a blood flow characteristic, by solving at least one of the modified three-dimensional model and the modified reduced order model; and identifying one of the plurality of treatment options that solves a function of at least one of: the determined blood flow characteristics of the patient's heart or vasculature, and one or more costs of each of the plurality of treatment options.

A method and system for patient-specific modeling of the whole heart anatomy, dynamics, hemodynamics, and fluid structure interaction from 4D medical image data is disclosed. The anatomy and dynamics of the heart are determined by estimating patient-specific parameters of a physiological model of the heart from the 4D medical image data for a patient. The patient-specific anatomy and dynamics are used as input to a 3D Navier-Stokes solver that derives realistic hemodynamics, constrained by the local anatomy, along the entire heart cycle. Fluid structure interactions are determined iteratively over the heart cycle by simulating the blood flow at a given time step and calculating the deformation of the heart structure based on the simulated blood flow, such that the deformation of the heart structure is used in the simulation of the blood flow at the next time step. The comprehensive patient-specific model of the heart representing anatomy, dynamics, hemodynamics, and fluid structure interaction can be used for non-invasive assessment and diagnosis of the heart, as well as virtual therapy planning and cardiovascular disease management. Parameters of the comprehensive patient-specific model are changed or perturbed to simulate various conditions or treatment options, and then the patient specific model is recalculated to predict the effect of the conditions or treatment options.

The use of music in connection with cancer therapy and other conditions is described. A computer-implemented method of modulating a mood in a person includes selecting an appropriate target mood, filtering a play list of music tracks based on an initial mood and vectoring by further filtering the play list to allocate the music tracks to play in order of appropriate stages creating a progressive modulation of mood from the initial mood to the target mood. A method of treating a patient with debilitating condition by administering to the patient a computer-implemented methodology is also provided.