428 results about "Optimal treatment" patented technology

The method of the present invention derives the illness probability of any selected person from a database of people stored in a computer and/or on a computer network using collected relational data from every person in the database, including whether a person has a contact relationship with another person in said database and utilizes a database of illnesses infection probability functions given different illnesses and states of nature including data relating to social relationship; type of disease; probability function of infection given a time unit; length of contact of the particular contact relationship link; and calculates at least one relational path between said person and each person in the data base with whom there is a contact relationship, direct or via other persons in the said database for deriving the illness probability of the selected person. In addition. the method of the present invention permits selecting the optimum treatment for a patient with an infectious disease based upon recommending a drug or drugs deemed optimum for treating the patient and permits generating alerts for the detection of emergency events such as the outbreak of an infectious disease or a biological, chemical or nuclear attack and for diseases management. Moreover, in accordance with the method of the present invention a given patient may compare his or her medical record with summary information of patients with similar defined criteria.

A medical digital expert system to predict a patient's response to a variety of treatments (using pre-treatment information) is described. The system utilizes data fusion, advanced signal/information processing and machine learning/inference methodologies and technologies to integrate and explore diverse sets of attributes, parameters and information that are available to select the optimal treatment choice for an individual or for a subset of individuals suffering from any illness or disease including psychiatric, mental or neurological disorders and illnesses. The methodology and system can also be used to determine or confirm medical diagnosis, estimate the level, index, severity or critical medical parameters of the illness or condition, or provide a list of likely diagnoses for an individual suffering/experiencing any illness, disorder or condition.

A system and a method for scheduling an emergency procedure in response to detecting that a patient has a high probability of acute myocardial infarction. The system is able to identify patients that are suspected of having acute myocardial infarction (or acute ischemia). The system uses one or more expert software tools or algorithms to analyze received ECG records. Each software tool has logic (e.g., thresholds and/or settings) for automatic routing which is configurable by the customer via a graphical user interface. If any sufficient condition for automatic routing is satisfied, the system routes the data (including the underlying ECG record) and an alert to an electronic device which is accessible by the cardiologist “on call” via a bidirectional pager. If the cardiologist decides that the requested emergency treatment or procedure should be performed, the system accesses the schedules of all associated catheterization labs across multiple hospitals to identify a lab having optimum time-to-treatment. Then the system automatically contacts the selected catheterization lab via a network to schedule the PTCA procedure.

The ultrasound therapeutic system of the present invention generally includes a generator unit, at least one transducer treatment head, and a programmable controller. The generator is in operable communication with the at least one transducer treatment head such that electric power outputted from the generator to the head is converted into acoustic power by the head. Re-programmable software at the controller generally controls all features and functions for the system. In particular, the controller calculates an initial optimal treatment dose, maintains effective acoustic power transmitted to the patient through the at least one treatment head, performs calibration procedures for the at least one treatment head, controls outputting for each supported treatment mode, and provides for various other features and functions.

An apparatus and method for automatically generating radiation treatment planning parameters are disclosed. In accordance with the illustrative embodiment, a database is constructed that stores: (i) patient data and past treatment plans by expert human planners for these patients, and (ii) optimal treatment plans that are generated using multi-objective optimization and Pareto front search and that represent the best tradeoff opportunities of the patient case, and a predictive model (e.g., a neural network, a decision tree, a support vector machine [SVM], etc.) is then trained via a learning algorithm on a plurality of input/output mappings derived from the contents of the database. During training, the predictive model is trained to identify and infer patterns in the treatment plan data through a process of generalization. Once trained, the predictive model can then be used to automatically generate radiation treatment planning parameters for new patients.

An improved system for screening a multiple of candidate therapeutic or chemotherapeutic agents for efficacy as to a specific patient, in which a tissue sample from the patient is harvested, cultured and separately exposed to a plurality of treatments and/or therapeutic agents for the purpose of objectively identifying the best treatment or agent for the particular patient. Specific method innovations such as tissue sample preparation techniques render this method practically as well as theoretically useful. One particularly important tissue sample preparation technique is the initial preparation of cohesive multicellular particulates of the tissue sample, rather than enzymatically dissociated cell suspensions or preparations, for initial tissue culture monolayer preparation. With respect to the culturing of malignant cells, for example, it is believed (without any intention of being bound by the theory) that by maintaining the malignant cells within a multicellular particulate of the originating tissue, growth of the malignant cells themselves is facilitated versus the overgrowth of fibroblasts or other cells which tends to occur when suspended tumor cells are grown in culture. Practical monolayers of cells may thus be formed to enable meaningful screening of a plurality of treatments and/or agents. Growth of cells is monitored to ascertain the time to initiate the assay and to determine the growth rate of the cultured cells; sequence and timing of drug addition is also monitored and optimized. By subjecting uniform samples of cells to a wide variety of active agents (and concentrations thereof), the most promising agent and concentration for treatment of a particular patient can be determined. For assays concerning cancer treatment, a two-stage evaluation is contemplated in which both acute cytotoxic and longer term inhibitory effect of a given anti-cancer agent are investigated.

The present invention involves a system and method of providing decision support for assisting medical treatment decision-making. A patient agent software module processes information about a particular patient. A doctor agent software module processes information about a health status of a particular patient, beliefs relating to patient treatments, and the actual effects of treatment decisions. By filtering information over time from the patient agent into the doctor agent, a plurality of decision-outcome nodes are created and formed into a patient-specific outcome tree with the plurality of decision-outcome nodes. An optimal treatment is determined by evaluating the plurality of decision-outcome nodes with a cost per unit change function to output the optimal treatment. When additional information is available from at least one of the patient agent and the doctor agent, the filtering, creating, and determining steps are repeated thus allowing for the system to “reason over time”, continuously updating and learning as new information is received.

A digital computer system stratifies in a set of patients, based on a set of observations. The observations can include physical, biochemical, histological, genetic, and gene-expression data, among other types of information. Adjustments can be made to account for the possibility that observations of several patients may begin at different points in the progression of their respective disease processes. Once these adjustments are made, the data are subjected to a statistical cluster analysis. Each cluster of patients potentially represents a different disease stratum, with its own underlying cause, optimum therapy, and prognosis. Once the strata are defined and patients are assigned to them, adjustments to the data can be refined. The cluster analysis then can be repeated, and so an iterative process of stratification and staging takes place.

The invention relates to a clinic path information system, which comprises a database, a path management terminal and a medical nursing terminal, wherein the path management terminal and the medical nursing terminal carry out data interaction with the database by a hospital information network; standard clinic path lists and an example implement library are stored in the database; and the path management terminal is used for managing and maintaining the standard clinic path lists. When a practical case is diagnosed and treated in a specific department, the medical nursing terminal collects the diagnosis and treatment data, and the disease type of the practical case is determined by the diagnosis and treatment data, thus the corresponding standard clinic path is introduced to the medical nursing terminal to carry out guided diagnosis and treatment and realize example implementation on the standard clinic path; and at the same time, in the guided diagnosis and treatment process, the implementation condition and implementation result can be recorded in real time, the diagnosis and treatment scheme of the practical case is dynamically determined, and the practical case is led to be the standard clinic path of the disease type, so that optimal treatment on the practical case is realized.

A radiation therapy patient couch top which provides optimal fields of treatment in a high-energy radiation therapy environment. In addition, the patient couch top provides superior imaging qualities when used in a diagnostic imaging x-ray environment. All metal is eliminated from the treatment/imaging area. This ensures that no metal will be in the way of the radiation treatment beam and that no artifacting will occur when used with diagnostic imaging techniques such as Computed Tomography. By employing moveable fiber reinforced support beams, the main patient support structure can be positioned so that a minimum of electron generation will occur through Compton scattering. By allowing for a removable insert, the top patient surface can be optimized for treatment, diagnostic imaging or the addition of other useful features. The novel design of these inserts allows the tip end of the beams to be free from any cross members, further improving the imaging and treatment qualities of the resulting patient couch top. Further, a CT simulator insert is provided which provides the same dosimetric properties for the patient couchtop and devices during patient treatment planning.

The invention relates to a sewage recycling comprehensive treatment technique, including that sewage is pretreated by a physicochemical technique and a biochemical technique; the pretreated sewage is separated by an immersed ultrafiltration solid-liquid separation system; ozone is used for eliminating part of organic matter and bacteria in the ultrafiltration membrane permeate liquid generated in the previous step; after being treated in the previous step, organic pollutant in the water is further removed by adopting activated carbon for filtering; after the treatment in the previous step, the water carries out reverse osmosis treatment to obtain permeate water of a reverse osmosis membrane, that is, reuse water. All sewage treatment techniques adopted by the invention are mutually matched, have reasonable sequence and play own roles independently, thus preventing the sewage treatment techniques from affecting with each other, allowing the equipment of each sewage treatment technique to achieve optimal treatment effect and leading to more complete sewage treatment.

The invention relates to a method for deciding an agile satellite earth observation task pretreatment scheme. A new target area decomposition and combination method is provided; a multi-attribute utility function is constructed according to a pretreatment method; task scheduling pretreatment schemes are sorted and selected according to the multi-attribute utility function method; a point target describing method based on 'moment-gesture' and a region target feature describing method based on time gesture vectors are provided; the describing method is utilized to provide a target decomposition and combination method in the pretreatment; for different parameter generating schemes, the optimal treatment scheme is selected through the multi-attribute utility function method.

The invention discloses an identification method of a salt-tolerant resource in the seedling period of cowpea, which is easy to operate and reliable in identification result. The identification method comprises the steps of carrying out germination experiment by adopting one cowpea variety to screen the optimal ultrasonic treatment method and determine the germination conditions; carrying out salt treatment experiment on three varieties by adopting salt solutions of multiple gradients to determine the optimal treatment condition; carrying out salt-tolerant experiment on 18 cowpea varieties of different genes, and carrying out principal component analysis to determine the optimal regression model. The identification method is used for identifying the salt-tolerant capability of the cowpea with 15d, and is short in identification time; the optimal salt-tolerant indexes of the cowpea are plant height, root length, plant dry weight and root dry weight, the identification method with simple operation and definite index is established, the shape indexes are visualized and convenient to count, and the standard identification method is provided for large-scale rapid identification of salt tolerance in the seedling period of the germplasm resource of the cowpea as well as the salt-tolerant variety selection and salt-tolerant mechanism.

An apnea classification system provides for apnea monitoring and differentiation based on several sleep apnea related parameters for diagnostic and therapeutic purposes. Monitoring of such sleep apnea related parameters allows the apnea classification system to differentiate among the different types of apnea. This information may then be used to determine the best method of therapy, or adjust current therapy parameters to more effectively treat a subject.

The invention discloses a low-emission solid organic waste treatment system realizing methane and active carbon production. The technical method of the low-emission solid organic waste treatment system realizing methane and active carbon production uses a waste crushing treatment system, an anaerobic digestion raw material pre-treatment and blending system, an anaerobic digestion reactor system, an anaerobic digestion residuum dehydrating system, an anaerobic digestion residuum carbonizing system, a carbonized gas collecting, heat-exchanging and purifying system, and a treatment water recycling system. The technical integration of the low-emission solid organic waste treatment system realizing methane and active carbon production is capable of finishing the optimal treatment of the biomass solid organic waste, and the final product is the clean energy methane and environment-friendly material active carbon. The partial required energy can be produced by the technical method, the energy recycling rate is high, and the treatment on the exhaust gas and effluent can be finished in the production link, the system is energy-saving and environment-friendly. By sufficiently considering the influence of various factors and the coherence among various links, the period of anaerobically treating the biomass organic solid waste can be obviously shortened, and the treatment efficiency of the organic solid waste can be sufficiently improved.