Product
Patsnap Eureka
For R&D, Patsnap Eureka makes reading and utilizing patents & technical documents easy.
Patsnap Eureka AIR
Designed for self-driven R&D workflows. Generate viable solutions, solve complex R&D challenges, empower your innovation with AI.
Patsnap Eureka Materials
Designed for material experts only. Revolutionize your material R&D, from search, analyze, to developing new materials.
Feature
TechResearch
Generate reliable direction feasibility study reports for your R&D in just a few steps.
TechSeek
Discover and master advanced knowledge NOW. Basics, ideas, possibilities, all at once.
TechMind
As an expert in R&D Theories, TechMind can generates customized viable solutions instantly.
TechRisk
Analyze your overall solution with one click, know your potential R&D risks in advance.
TechMonitor
Get weekly tech updates, stay abreast of the latest tech innovations and key insights.
Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
46 results about "Deoxygenated Hemoglobin" patented technology
Efficacy Topic
Property
Owner
Technical Advancement
Application Domain
Technology Topic
Technology Field Word
Patent Country/Region
Patent Type
Patent Status
Application Year
Inventor
Hemoglobin containing a heme group that is not bound to oxygen (O2). This molecule is normally found in the systemic veins following transit through capillaries and release of O2 into the tissues. Excess deoxyhemoglobin can be associated with hypoxia.
Modified Pulse Oximetry Technique For Measurement Of Oxygen Saturation In Arterial And Venous Blood
A method for the measurement of oxygen saturation in arterial blood SaO2 by means of pulse oximetry without calibration is described. Photoplethysmography (PPG) is measured in three wavelengths in the infrared and for each PPG curve the relative change in light transmission is obtained. Two equations, each relating SaO2 to the ratio of the relative changes in light transmission for two wavelengths, using the values of the extinction coefficients of oxygenated and deoxygenated hemoglobin for the three wavelengths, enable the determination of SaO2, assuming linear dependence of the optical path-length on the wavelength, for the three wavelengths in the infrared. Similar technique for the determination of oxygen saturation in venous blood from changes in light transmission due to changes in venous blood volume is suggested
Owner:JERUSALEM COLLEGE OF TECHNOLOG
Hemoglobin compositions
ActiveUS20100311657A1Extended half-lifeReduce chancePeptide/protein ingredientsEnergy modified materialsDiseaseHEMOGLOBIN I
The invention provides compositions containing hemoglobin, particularly PEGylated hemoglobin. The PEGylated hemoglobin molecule is capable of transferring oxygen or carbon monoxide bound thereto to a tissue with which it is in proximity. Exemplary PEGylated hemoglobin formulations of the invention are virally inactivated. Various compositions of the invention include deoxygenated hemoglobin, which may be conjugated with one or more water-soluble polymer. PEGylated hemoglobin includes those species in which the iron atom of the hemoglobin molecule is not bound to oxygen or any other species, and hemoglobin molecules in which a species other than oxygen, e.g., carbon monoxide, is bound to the iron atom. The compositions of the invention are formulated as hypo-, iso- or hypertonic solutions of the PEGylated hemoglobin. The compositions are of use to treat and / or ameliorate disease, injury and insult by providing for the oxygenation of tissues and / organs.
Owner:PROLONG PHARMA
Method and apparatus for performing qualitative and quantitative analysis of burn extent and severity using spatially structured illumination
Frequent monitoring of early-stage burns is necessary for deciding optimal treatment and management. Superficial-partial thickness and deep-partial thickness burns, while visually similar, differ dramatically in terms of clinical treatment and are known to progress in severity over time. The disclosed method uses spatial frequency domain imaging (SFDI) far noninvasively mapping quantitative changes in chromophore and optical properties that may be an indicative of burn wound severity. A controlled protocol of graded burn severity is developed and applied to 17 rats. SFDI data is acquired at multiple near-infrared wavelengths over a course of 3 h. Burn severity is verified using hematoxylin and eosin histology. Changes in water concentration (edema), deoxygenated hemoglobin concentration, and optical scattering (tissue denaturation) are statistically significant measures, which are used to differentiate superficial partial-thickness burns from deep-partial thickness burns.
Owner:RGT UNIV OF CALIFORNIA
Preserving a hemoglobin blood substitute with a transparent overwrap
InactiveUS7041800B1High purityExtended shelf lifePeptide/protein ingredientsMetal layered productsPolyolefinMedicine
Owner:OPK BIOTECH
Spectroscopic method and apparatus for total hemoglobin measurement
InactiveUS20050019936A1Scattering properties measurementsLaboratory glasswaresTotal hemoglobinAbsorbance
A method and apparatus for measuring Tot-Hb in a sample are provided. The method comprises collecting absorbance measurements of a sample using a spectroscopic apparatus that comprises a first primary calibration algorithm for one of Oxy-Hb, “Oxy-Hb plus Deoxy-Hb”, or “Total-Hb minus Met-Hb” and a second primary calibration algorithm for one or more than one of Met-Hb, Carboxy-Hb, or Sulf-Hb, or comprising a third primary calibration algorithm obtained by adding terms of the first primary calibration algorithm and the second primary calibration algorithm together. Followed by predicting either a first value for one of Oxy-Hb, “Oxy-Hb plus Deoxy-Hb,” or “Total-Hb minus Met-Hb” and predicting second value for one or more than one of Met-Hb, Carboxy-Hb, or Sulf-Hb in the sample and add the first and second value together, or predicting a value for Total-Hb.
Owner:TYCO HEALTHCARE GRP LP
Apparatus for evaluating biological function
InactiveUS7065392B2Improve reliabilityReduce processing loadDiagnostic recording/measuringSensorsOxygenated HemoglobinOxygen
The present invention provides an apparatus for evaluating biological function that, in differentiating as far as possible information from the capillaries, which reflects tissue metabolism, from information from outside the tissue (for example, the arteries and veins), has high speed and accuracy enabling it to compensate for the low spatial resolution of conventional near infrared spectroscopy methods, and that furthermore does not merely monitor changes in oxygen concentration and the like, but makes it possible to easily and conveniently distinguish between capillary reactions, metabolic reactions and the like; its configuration is characterized in that it provides a light irradiation means for irradiating light to a specified site of a living body, a light detection means for detecting light exiting from the living body, a calculation means for determining the respective changes in concentration of oxygenated hemoglobin and deoxygenated hemoglobin by performing calculations in near infrared spectroscopy with the intensity of the detected light as a parameter, and a display means for displaying information concerning the relative ratio “k” between both these data over time.
Owner:KATO
Wireless disposable shock trauma monitoring device
InactiveUS20130096401A1Small sizeEasy to useDiagnostic recording/measuringSensorsCalorescencePhotodetector
Apparatus for monitoring oxygen saturation levels in tissue for a miniature wireless disposable optical tissue oximeter to are disclosed. According to one aspect of the present invention, a sensor contains a first light source, a second light source, a photodetector, and a skin contact detector. Once skin contact is detected, the first light source emits light in the near infrared region, and the second light source emits light in the visible red region. The emitted light passes through a transparent layer of an adhesive fixation unit, and enters the underlying tissue, where a portion of the light is absorbed by tissue chromophores, including oxygenated hemoglobin and deoxygenated hemoglobin, and reflected back out of the tissue into the photodetector. The oxygen saturation of the tissue under the sensor is then calculated. The oxygen saturation measurements are wirelessly transmitted to a remote display device, such as a smartphone running a smartphone software application which receives the measurements and displays them in numeric, graphical, and audible form. In addition, the smartphone software application may relay the data to the Internet for remote viewing on a web site or remote transfer to a hospital patient data system.
Owner:INNOVAMEDIX
Preserving a hemoglobin blood substitute with a transparent overwrap
InactiveUS20060160724A1High purityExtended shelf lifeWrappersPeptide/protein ingredientsMedicineBlood substitute
The invention relates to a method for preserving the stability of a hemoglobin blood substitute comprising maintaining the hemoglobin blood substitute in an atmosphere substantially free of oxygen. The method for preserving the deoxygenated hemoglobin blood substitute comprises maintaining the deoxygenated blood substitute in an oxygen barrier film overwrap package, wherein at least one face of the overwrap package comprises a transparent laminate material and wherein at least one other face of the overwrap package comprises a foil laminate material. The preserved deoxygenated hemoglobin blood substitute comprises a deoxygenated hemoglobin blood substitute and an oxygen barrier film overwrap package wherein at least one face of the overwrap package comprises a transparent laminate material and wherein at least one other face of the overwrap package comprises a foil laminate material.
Owner:OPK BIOTECH
Blood Oxygenation Sensor
InactiveUS20070197888A1Representative measurementHigh sensitivityMaterial analysis by optical meansCatheterRefractive indexOxygen
A planar dielectric waveguide sensor is used to determine the concentrations of oxygenated and deoxygenated hemoglobin and other blood constituents such as pH, sugar. The planar waveguide core is in direct contact with the blood such that evanescent field of the light propagating within the core is selectively attenuated at specific wavelengths of interest. The planar waveguide has a construction that promotes strong interaction of the evanescent field with blood cells that contact it. In preferred embodiments, the waveguide is constructed of a low refractive index core to propagate an evanescent wave comparable in size to a red blood cell.
Owner:PHYSICAL LOGIC
Biological light measurement device
The mental state, such as mood or emotion, of an individual can be apprehended by a method using non-invasive biological light measurement technology. A biological light measurement device, which has an irradiation section, presents different tasks (at least a first task and a second task) to a subject, hemoglobin signals based on changes in the concentration of oxygenated hemoglobin and deoxygenated hemoglobin in the subject are calculated from the strength of light detected by a detection section, and a relative value using the hemoglobin signal at a predetermined measurement channel with respect to the first task, and the hemoglobin signal at a different predetermined measurement channel with respect to the second task is calculated.
Owner:HITACHI LTD
Magnetic resonance imaging method for measuring R2, R2* and R2' parameter image of tissue in noninvasive and dynamic manner
InactiveCN105699923AReduce contributionFlexible settingsDiagnostic recording/measuringSensorsUltrasound attenuationImage resolution
The invention discloses a magnetic resonance imaging method which utilizes the fact that a tissue with different deoxygenated hemoglobin content has magnetic sensitive chatacteristics of different degrees, uses an asymmetric spin echo magnetic resonance imaging sequence, adopts a strategy of moving a 180-degree echo refocusing RF pulse position periodically, allows 180-degree echo refocusing pulses to distribute on both sides of a TE / 2 time position in each period, and obtains a high-time-resolution multiple-echo image. Further, aiming at acquired multiple-echo signals, the magnetic resonance imaging method performs mobile estimation by taking length of a corresponding 180-degree echo refocusing pulse mobile period as a window width, adopts least square estimation, and obtains dynamic parameter images of R2, R2* and R2' simultaneously according to a signal attenuation index model. By adopting the magnetic resonance imaging method, the high-time-resolution dynamic R2, R2* and R2' parameter images can be obtained, and a dynamic curves in an arbitrary region of interest can be displayed.
Owner:PEKING UNIV
Continuous monitoring of tumor hypoxia using near-infrared spectroscopy and tomography with a photonic mixer device
ActiveUS9788770B1Television system detailsDiagnostics using spectroscopyAbnormal tissue growthMedicine
A device and a method to measure the concentrations of oxygenated and deoxygenated hemoglobin in tissue around a tumor via near-infrared (NIR) spectroscopy with a photonic mixer device (PMD) is described.
Owner:VERILY LIFE SCI LLC
Device for measuring oxygenated hemoglobin and deoxygenated hemoglobin and brain imaging device
InactiveCN108056777AIncrease usageSimple configurationDiagnostic recording/measuringSensorsOxygenated HemoglobinEngineering
The invention discloses a device for measuring oxygenated hemoglobin and deoxygenated hemoglobin and a near infrared brain imaging device. The device comprises an interface module, a near infrared receiving and transmitting module and a controller, wherein the near infrared transceiving module is provided with a plug-and-play interface and plugged in the interface module through the plug-and-playinterface, the near infrared receiving and transmitting module is driven by the controller to transmit preset-wavelength near infrared rays to measured cerebral cortex and receive light intensity signals generated when the near infrared rays are reflected by the measured cerebral cortex. The controller is connected with the interface module and used for receiving the light intensity signals outputby the near infrared receiving and transmitting module and measuring parameters of oxygenated hemoglobin and deoxygenated hemoglobin of the measured cerebral cortex according to the light intensity signals. Thus, according to the characteristic that hot plug is supported by the near infrared receiving and transmitting module, the aims of increasing and decreasing functions and channel number canbe realized, and the reusability of the device and the usage rate of parts can be increased.
Owner:北京心灵方舟科技发展有限公司
Identification method of movement velocity state based on cerebrum hemoglobin information
InactiveCN106901751ASolve psychological problemsAddress ethical issuesDiagnostic recording/measuringSensorsLearning machineFeature vector
The invention discloses an identification method of a movement velocity state based on cerebrum hemoglobin information. The method comprises the first step of making a testee autonomously execute riding movement under low-velocity, middle-velocity and high-velocity states; the second step of aiming at cortex hemoglobin concentration information recorded in the movement initial time, adopting a difference value of oxygen-containing hemoglobin and deoxygenated hemoglobin as an analysis parameter, and considering parameter characteristics of key channels via four frequency bands respectively based on a change rate mean value of the corresponding difference value; the third step of identifying three different kinds of velocity states. The change rate mean value of the difference value of the oxygen-containing hemoglobin and deoxygenated hemoglobin of the key channels under four frequency bands is directly utilized as a feature vector, and an extreme learning machine ELM algorithm is adopted to identify velocity grades.
Owner:SUZHOU UNIV
Near-infrared brain imaging spectrum classifying method based on cognition task testing
InactiveCN106037645AHigh reference valueHigh research valueDiagnostics using spectroscopySensorsClassification methodsBasic research
The invention discloses a near-infrared brain imaging spectrum classifying method based on cognition task testing. A near-infrared brain imaging spectrum at least comprises a first curve corresponding to the oxyhemoglobin concentration and a second curve corresponding to the deoxygenated hemoglobin concentration. The classifying method comprises the following specific steps: 1, reading the near-infrared brain imaging spectrum obtained by a near-infrared brain imager, and extracting the waveform characteristics of the first curve and the second curve of the near-infrared brain imaging spectrum; and 2, comparing the waveform characteristics obtained in the step 1 with a preset value, and classifying the near-infrared brain imaging spectrum according to the comparison result. The near-infrared brain imaging spectrum classifying method based on the cognition task testing provided by the invention can be applied to the fundamental research in the field of psychology or applied to the clinic for automatically classifying the near-infrared brain imaging spectrum.
Owner:清华大学玉泉医院 +1
Improved polymerized hemoglobin preparation method
InactiveCN103524614ALow average molecular weightImprove effective conversion rateHaemoglobins/myoglobinsPolymer scienceHemoglobin hb
The invention relates to an improved polymerized hemoglobin preparation method. According to the invention, a hemoglobin aqueous solution with matrix-free human deoxyhemoglobin weight / volume content of 4-14% is adopted as a raw material. Under an inert gas environment and a stirring condition, an aldehyde-type bi-functional crosslinking agent is delivered into the raw material solution through a titanium rod; a polymerization reaction is carried out under a temperature of 0-10 DEG C, such that polymerized hemoglobin with an average molecular weight of 100-210kD and a preferable molecular weight of 110-170kD is obtained. A molar ratio of hemoglobin to the aldehyde-type bi-functional crosslinking agent is 4-8:1. With the method, the polymerized hemoglobin product with relatively low average molecular weight, relatively narrow molecular weight distribution, and effective conversion rate reaching 69% can be prepared, such that a problem of non-uniform molecular weight distribution in product of current polymerized hemoglobin preparation is effectively avoided. The operation is simple, and equipment cost is low.
Owner:BLOOD TRASFUSION INST CHINESE ACAD OF MEDICAL SCI
Predicting Weight Loss and Fat Metabolism Using Optical Signal Changes in Fat
ActiveUS20170209089A1Reduce morbidityExtend your lifeSurgeryMedical automated diagnosisPhotodetectorSpectroscopy
A quantitative, non-invasive optical spectroscopy technique for measuring dynamic changes in adipose tissue structure and metabolism in vivo. The technique requires multiple wavelengths of light in the near-infrared (650-1000 nm). Using these wavelengths of light, adipose tissue is illuminated and light that returns to a photodetector is analyzed. From the return signals, the absorption and reduced scattering coefficients (μa and μs′) at each wavelength are calculated. The obtained pa and μs′ values allow for quantification of biomarkers and indices which allow for measurement of fat composition and metabolism. The concentration of oxy- and deoxy-hemoglobin, the fractional water and lipid content, and information about the size distribution of light scatterers in the adipose tissue are also determined. A detailed and quantitative understanding of fat composition and metabolism is thereby provided which describes the effectiveness of interventions to improve the health of a patient.
Owner:RGT UNIV OF CALIFORNIA
Device and method for quantitatively detecting spectral content distribution of oxygenated hemoglobin and deoxygenated hemoglobin
ActiveCN103411901AHigh precisionGet comprehensive informationColor/spectral properties measurementsContent distributionDecomposition
The invention relates to a device for quantitatively detecting the spectral content distribution of oxygenated hemoglobin and deoxygenated hemoglobin. The device comprises a light source module, an imaging module, an adjusting bracket, an image data transmission link, a control command transmission link and a computer. As a technical means of high spectral imaging is adopted, the full cover detection is realized in a detected region, and a characteristic spectrum of the oxygenated hemoglobin and the deoxygenated hemoglobin is extracted through using a spectral decomposition technology, the calculation is carried out by utilizing a regional oxygen saturation computational formula, and the device and the method have the characteristics of acquiring comprehensive information and being high in precision without any reagent.
Owner:SHANDONG UNIV
Device and method for measuring oxygen-containing hemoglobin and deoxygenated hemoglobin and equipment
ActiveCN108113682AImprove use adaptabilityMaterial analysis by optical meansSensorsLuminous intensityOxygen
The invention discloses a method and device for measuring oxygen-containing hemoglobin and deoxygenated hemoglobin and equipment. The device comprises a near-infrared emission module, a near-infraredreceiving module and a controller, wherein the near-infrared emission module is used for emitting near-infrared light of target compound waveforms to the tested cerebral cortex, the near-infrared receiving module is used for receiving a luminous intensity signal, reflected by the tested cerebral cortex, of the near-infrared light, and the controller is used for receiving target measuring requirement parameters, adjusting the near-infrared light waveforms emitted by the near-infrared emission module according to the target measuring requirement parameters to obtain the target compound waveforms, controlling the near-infrared emission module to emit the near-infrared light according to the target compound waveforms, receiving luminous intensity information output by the near-infrared receiving module, and measuring oxygen-containing hemoglobin parameters and deoxygenated hemoglobin parameters of the tested cerebral cortex according to the luminous intensity information. In this way, thefunction of dynamically adjusting output waveforms to adapt to different testing items and different testees is achieved, and the using adaptability of products is improved.
Owner:北京心灵方舟科技发展有限公司
Method and apparatus for selective photothermolysis of veins
InactiveUS20110224656A1Facilitates selective absorptionReduce fluenceSurgical instrument detailsLight therapyOxygenated HemoglobinElectromagnetic radiation
Exemplary embodiments of the present disclosure provide method and apparatus for providing electromagnetic radiation to a biological tissue that may be selectively absorbed by venous structures as compared to arteries. For example, a wavelength of the electromagnetic radiation can be selected based on absorptivity of the radiation by oxygenated hemoglobin, deoxygenated hemoglobin, and / or met-hemoglobin. The wavelength can be, e.g., between about 685 nm and about 705 nm, or between about 690 nm and about 700 nm, or about 694 nm. The exemplary methods and apparatus can be used, e.g., for photothermolysis treatment of venous structures such as port wine stains or varicose veins, while reducing or avoiding undesirable damage to nearby arteries in the irradiated tissue.
Owner:THE GENERAL HOSPITAL CORP
Preserving a hemoglobin blood substitute with a transparent overwrap
InactiveUS20020128182A1High purityLong shelf lifePeptide/protein ingredientsMammal material medical ingredientsCross-linkMedicine
The invention relates to a method for preserving the stability of a hemoglobin blood substitute comprising maintaining the hemoglobin blood substitute in an atmosphere substantially free of oxygen. The invention also involves a method for producing a stable polymerized hemoglobin blood-substitute from blood. The method of this invention includes mixing blood with an anticoagulent to form a blood solution, washing the red blood cells in the blood solution and then separating the washed red blood cells from the white blood cells. This method also includes disrupting the red blood cells to release hemoglobin and form a hemoglobin solution, which is then treated by high performance liquid chromatography to form a hemoglobin eluate. The hemoglobin eluate is then deoxygenated, contacted with a first sulfhydryl compound to form an oxidation-stabilized deoxygenated hemoglobin solution, and mixed with a cross-linking agent to form a polymerization reaction mixture, which is then polymerized. The polymerized hemoglobin solution is then diafiltered with a physiologic solution and with a sulfhydryl compound, whereby the polymerized hemoglobin solution is made physiologically acceptable, and whereby the sulfhydryl compound scavenges oxygen, to form a stable polymerized hemoglobin blood-substitute, which is then packaged and stored in an atmosphere substantially free of oxygen.
Owner:OPK BIOTECH
Optical imaging method based on layer structure
ActiveCN107752981AAccurate assessment of detection depthDiagnostic signal processingDiagnostics using lightOptical propertyOxygen
Owner:WENZHOU MEDICAL UNIV
Biological photometric device
InactiveUS20090054885A1Diagnostics using lightVaccination/ovulation diagnosticsTime changesOxygenated Hemoglobin
A biological photometric device includes a light irradiating unit for irradiating an object to be examined with light having a predetermined wavelength and sympathizing with oxygenated hemoglobin and deoxygenated hemoglobin through an optical fiber, a light detecting unit for detecting and amplifying light passing through a detecting optical fiber and the object as detected signals, a signal processing unit adapted for computing hemoglobin time change information based on oxygenated hemoglobin, deoxygenated hemoglobin and total hemoglobin in the object from the detected signals light detecting unit, and including a noise detector for arithmetically processing the detected signals and determining / detecting whether the time change information is noise attributed to the presence of obstacles to passing of light between the object and the end face of the optical fiber or noise attributed to the damage to the light irradiating unit, and a display unit for displaying the noise signals.
Owner:HITACHI LTD
Method for making polyalkylene oxide modified hemoglobin
ActiveUS20100075379A1Haemoglobins/myoglobinsMammal material medical ingredientsAnimal SourcesDeoxygenated Hemoglobin
The present invention is a method for preparing a hemoglobin based oxygen carrier to deliver oxygen to tissue. The method comprises mixing a deoxygenated hemoglobin with a maleimide-activated polyakylene oxide (PAO) to obtain an oxygen carrying product. This product is characterized as having 2 to about 8 PAO moieties covalently bound to a deoxygenated hemoglobin and a p50 less than native stroma-free hemoglobin from the same animal source when measured under the same conditions.
Owner:SANGART INC
Cortical functional multi-mode imaging system
ActiveCN101926644BSimultaneously monitor changesSimultaneous monitoring of pHDiagnostic recording/measuringSensorsLight-emitting diodeMaterials science
The invention discloses a cortical functional multi-mode imaging system. The system comprises a wide-spectrum light source, a laser diode and a red light-emitting diode which are arranged above cortex dispersedly; a coaxial filter is respectively arranged in front of the wide-spectrum light source and the red light-emitting diode; backward scattered light come from the cortex is split into two paths by a dispersion prism; one path of the backward scattered light is connected with a first charge coupled device through a liquid crystal tunable filter; the other path of the backward scattered light is connected with a second charge coupled device through a filter; and the two charge coupled devices are respectively connected with two computers. The system solves the difficult problem of technology integration of fluorescence imaging and intrinsic signal optical imaging for a long time by introducing the liquid crystal tunable filter; and the intracellular pH value, cerebral blood volume,deoxygenated hemoglobin and cerebral blood flow changes can be obtained at the same time by combining laser speckle imaging so as to provide an effective means for researching brain functions and disease mechanisms more completely in detail.
Owner:HUAZHONG UNIV OF SCI & TECH
Photoacoustic and ultrasonic bimodal imaging system and method for transplanted kidneys
InactiveCN111493816AEnable structural imagingSimultaneous real-time imaging of structuresOrgan movement/changes detectionDiagnostic recording/measuringUltrasonic sensorKidney
The invention discloses a photoacoustic ultrasonic bimodal imaging system and method for transplanted kidney. The system comprises a pulse laser which is used for the transplanted kidney to generate an photoacoustic signal; the ultrasonic transducer is used for receiving the photoacoustic signal and converting the photoacoustic signal into an electric signal; the ultrasonic transceiving module isused for transmitting and receiving electric signals; a photoacoustic signal processing unit; a data collection unit; and the computer is used for controlling the pulse laser and the ultrasonic transceiving module, performing image reconstruction on the digitized photoacoustic signal to obtain a photoacoustic image, and performing color coding on the photoacoustic image to realize development of functional information such as transplanted kidney microvascular distribution, intravascular blood oxygen content, oxygenated / deoxygenated hemoglobin content and the like. Structural imaging of the transplanted kidney can be achieved, functional information such as castruty distribution, intravascular blood oxygen content and oxygenated / deoxygenated hemoglobin content of the transplanted kidney canbe provided, and namely simultaneous real-time imaging of the structure and the function of the transplanted kidney is achieved.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV
Biological photometric device
Owner:HITACHI LTD
Noninvasive exercise fatigue intervention and evaluation method
PendingCN113952633AAvoid complexityAvoid invasiveElectrotherapyDiagnostic recording/measuringTranscutaneous Acupoint Electrical StimulationUpper limb
The invention discloses a non-invasive exercise fatigue intervention and evaluation method. The method comprises the following steps: step 1, a laser acupuncture and moxibustion combined percutaneous acupoint electrical stimulation composite intervention method is adopted, and laser and current synchronous stimulation is realized by using a composite intervention probe; and step 2, an an exercise fatigue and intervention effect assessment method is adopted by means of firstly, establishing an upper limb fatigue model for exercise fatigue assessment, then establishing an exercise fatigue fusion assessment model by using indexes such as a visual simulation score table, oxygenation / deoxygenated hemoglobin concentration, surface electromyogram signals, maximum equal-length contraction tension and the like, and then adopting the fusion evaluation model for verifying the intervention effect of laser acupuncture and moxibustion combined percutaneous acupoint electrical stimulation composite intervention on exercise fatigue through a control experiment. The invention provides a new clinical thought for preventing and treating exercise fatigue, and has important significance in improving the athletic performance of athletes, reducing the risk of exercise injury and diseases and encouraging people to exercise so as to promote physical and psychological health.
Owner:TIANJIN UNIV
Cerebral blood oxygen detection system and method
PendingCN112641444AEliminate constant parametersHigh measurement accuracyDiagnostic signal processingSensorsOptical pathlengthLight source
The invention belongs to the field of cerebral blood oxygen detection, and provides a cerebral blood oxygen detection system. The cerebral blood oxygen detection system comprises an acquisition module and a data processing module, wherein the acquisition module comprises N groups of light sources and M groups of detectors, the N groups of the light sources and the M groups of the detectors are arranged on the same side of a to-be-detected sample, and the N groups of the light sources emit at least three kinds of near-infrared light with different wavelengths into the to-be-detected sample; at least two groups of the detectors in the M groups of the detectors respectively receive near-infrared light signals which are not absorbed by the to-be-detected sample; and the data processing module is used for processing the near-infrared light signals according to the corrected Lambert-Beer law to obtain cerebral blood oxygen information of the to-be-detected sample. The system solves the technical problems that in the prior art, when the cerebral blood oxygen information is detected, the light sources and the detectors are arranged on two sides of the to-be-detected sample respectively, an optical density signal needs to penetrate through the tissue of the to-be-detected sample, the optical path is long, interference of other chromophores except oxygen-containing hemoglobin and deoxidized hemoglobin in the calculation process is large, and the calculation result error is larger.
Owner:SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
Method for making polyalkylene oxide modified hemoglobin
InactiveUS8021858B2Haemoglobins/myoglobinsMammal material medical ingredientsHEMOGLOBIN IHemoglobin F
The present invention is a method for preparing a hemoglobin based oxygen carrier to deliver oxygen to tissue. The method comprises mixing a deoxygenated hemoglobin with a maleimide-activated polyakylene oxide (PAO) to obtain an oxygen carrying product. This product is characterized as having 2 to about 8 PAO moieties covalently bound to a deoxygenated hemoglobin and a p50 less than native stroma-free hemoglobin from the same animal source when measured under the same conditions.
Owner:SANGART INC
Who we serve
- R&D Engineer
- R&D Manager
- IP Professional
Why Patsnap Eureka
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com