3195results about "Diagnostic signal processing" patented technology

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

A sensor interface is configured to receive a sensor signal. A transmitter modulates a first baseband signal responsive to the sensor signal so as to generate a transmit signal. A receiver demodulates a receive signal corresponding to the transmit signal so as to generate a second baseband signal corresponding to the first baseband signal. Further, a monitor interface is configured to communicate a waveform responsive to the second baseband signal to a sensor port of a monitor. The waveform is adapted to the monitor so that measurements derived by the monitor from the waveform are generally equivalent to measurements derivable from the sensor signal. The communications adapter may further comprise a signal processor having an input in communications with the sensor interface, where the signal processor is operable to derive a parameter responsive to the sensor signal and where the first baseband signal is responsive to the parameter. The parameter may correspond to at least one of a measured oxygen saturation and a pulse rate.

An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor.

Support structures for positioning sensors on a physiologic tunnel for measuring physical, chemical and biological parameters of the body and to produce an action according to the measured value of the parameters. The support structure includes a sensor fitted on the support structures using a special geometry for acquiring continuous and undisturbed data on the physiology of the body. Signals are transmitted to a remote station by wireless transmission such as by electromagnetic waves, radio waves, infrared, sound and the like or by being reported locally by audio or visual transmission. The physical and chemical parameters include brain function, metabolic function, hydrodynamic function, hydration status, levels of chemical compounds in the blood, and the like. The support structure includes patches, clips, eyeglasses, head mounted gear and the like, containing passive or active sensors positioned at the end of the tunnel with sensing systems positioned on and accessing a physiologic tunnel.

Abstract of the DisclosureThe preferred embodiments provide a membrane system, particularly for use on an electrochemical sensor, wherein the membrane system includes an affinity domain that dampens the effects of target interferant(s) on the sensor. The affinity domain can be layer, surface, region, and / or portion of the membrane system formed using sorbents that have an affinity for the target interferant. The sorbents can be adapted to adsorb the interferants, for example using adsorbents such as chromatography packing materials. The sorbents can also be adapted to absorb the interferants by imprinting a molecular structure on the material that forms the affinity domain such that target interferants bind to the imprinted surfaces at the molecular level.

An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor.

The present invention relates to a method for estimating blood glucose levels using a noninvasive optical coherence tomography- (OCT-) based blood glucose monitor. An algorithm correlates OCT-based estimated blood glucose data with actual blood glucose data determined by invasive methods. OCT-based data is fit to the obtained blood glucose measurements to achieve the best correlation. Once the algorithm has generated sets of estimated blood glucose levels, it may refine the number of sets by applying one or more mathematical filters. The OCT-based blood glucose monitor is calibrated using an Intensity Difference plot or the Pearson Product Moment Correlation method.

A wearable platform embodied in a belt or patch provides physiological monitoring of soldiers during field operations or trauma victims at accident sites and makes health state assessments. The platform includes sensors for heart rate, body motion, respiration rate and intensity, and temperature and further contains a microprocessor and short range transmitter. An analog circuit running an algorithm obtains the R-wave period from the EKG signal and produces electrical pulses with the period between pulses corresponding to the R-wave period. A rule based processing engine having an evaluation algorithm is capable of making a medical evaluation of subject condition and determines a confidence level for the evaluation. The rules are subject to variation depending upon the subject population. The information is communicated wirelessly to a local hub for relay to a remote monitor.

A medical monitor includes a lanyard and an electronic package supported in the manner of a pendant. The lanyard includes integral electrodes or other sensors for making physiological measurements, auxiliary components and connectors for electrically connecting the electrodes or sensors to the electronic package. The physiological measurements may be stored in the monitor for later readout, or may be transmitted, before or after processing, to a remote location.

A wearable platform embodied in a belt or flattened patch-like central body shaped to conform to the abdomen provides physiological monitoring of soldiers during field operations or trauma victims at accident sites and makes health state assessments. The platform includes sensors for heart rate, body motion, respiration rate and intensity, and temperature and further contains a microprocessor and short range transmitter. The respiration sensor uses conductive ink in a novel manner. A small square of the ink is coated on an arched structure so that flexing of the arch either to increase or decrease its radius of curvature modifies the resistance of the structure. This is utilized to set the unstressed resistance of the arch structure and to allow a greater range of resistance values capable of measuring distortions in different deformations of the arch. The respiration sensor supplements the motion information provided by an accelerometer sensor.

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

An apparatus for insertion of a medical device in the skin of a subject is provided.

Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the device has a sensing mechanism and a sensing membrane that includes at least one surface-active group-containing polymer and that is located over the sensing mechanism. The sensing membrane may have a bioprotective layer configured to substantially block the effect and / or influence of non-constant noise-causing species.

A method for diagnosing a joint condition includes in one embodiment: creating a 3d model of the patient specific bone; registering the patient's bone with the bone model; tracking the motion of the patient specific bone through a range of motion; selecting a database including empirical mathematical descriptions of the motion of a plurality actual bones through ranges of motion; and comparing the motion of the patient specific bone to the database.

An apparatus comprising a user interface configured to generate an electrical signal to start a basal insulin rate test when prompted by a user, an input configured to receive sampled blood glucose data of a patient that is obtained during a specified time duration, including a time duration during delivery of insulin according to a specified basal insulin rate pattern, and a controller communicatively coupled to the input and the user interface. The controller includes an insulin calculation module configured for determining at least one of an amount of basal insulin over-delivered and an amount of basal insulin under-delivered during the basal insulin rate test in trying to meet a target blood glucose baseline. Other devices and methods are disclosed.

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

An apparatus and method for determining tissue oxygenation such as arterial and venous oxygenation and cerebral oxygenation. In one embodiment the optical properties of tissue are determined using measured light attenuations at a set of wavelengths. By choosing distinct wavelengths and using light attenuation information, the influence of variables such as light scattering, absorption and other optical tissue properties can be minimized.

A device for acquiring data and diagnosing a musculoskeletal injury. The device includes a semi-flexible housing, at least one ultrasonic transducer, a positional localizer, and a transmission system. The semi-flexible housing is positioned proximate a portion of the musculoskeletal system of a patient and supports the at least one ultrasonic transducer and the positional localizer. The at least one ultrasonic transducer is configured to acquire an ultrasonic data indicative of a bone surface. The positional localizer is positioned at a select location relative to the at least one ultrasonic transducer and tracks movement of the housing. The transmission system transmits the ultrasonic data of the at least one ultrasonic transducer and the movement data of the positional localizer to a data analyzer for analysis and diagnosis.

A medical monitor includes a lanyard and an electronic package supported in the manner of a pendant. The lanyard includes integral electrodes or other sensors for making physiological measurements, auxiliary components and connectors for electrically connecting the electrodes or sensors to the electronic package. The physiological measurements may be stored in the monitor for later readout, or may be transmitted, before or after processing, to a remote location.

A closed loop brain-machine interface is disclosed. The closed loop brain-machine interface translates one or more neural signals into a movement, or a series of movements, performed by a machine. The close-loop brain-machine interface also provides sensory feedback to the subject. Methods of employing the closed loop brain-machine interface are also disclosed.

The invention is a medical monitor including an electronic circuit configured to receive a signal from the physiological sensor. A microcomputer configured to process the signal from the physiological sensor generates a value representative of the physiological parameter. The microcomputer is also configured to cause the medical monitor to display an in-service help screen on a display on the medical monitor in response to a detection of a predetermined number of out of range values of the physiological parameter. The microcomputer can also be configured to process a second signal from a second sensor representative of a second parameter and the microcomputer configured to cause the medical monitor to display an in-service help screen on a display on the medical monitor in response to a detection of a predetermined number of out of range values of the second parameter.

A system for determining electrophysiological data comprising an electronic control unit configured to acquire electrophysiology signals from a plurality of electrodes (130) of one or more catheters, select at least one clique of electrodes from the plurality of electrodes (136) to determine a plurality of local E field data points, determine the location and orientation of the plurality of electrodes, process the electrophysiology signals from the at least one clique from a full set of bipole subcliques to derive the local E field data points associated with the at least one clique of electrodes, derive at least one orientation independent signal from the at least one clique of electrodes (138) from the information content corresponding to weighted parts of electrogram signals, and display or output catheter orientation independent electrophysiologic information to a user or process.

Provided are embodiments of systems, computer medium and computer-implemented methods for monitoring the health of an employee. A method for monitoring the health of an employee including collecting health data corresponding to at least one of biometric health data and biomechanical health data for an employee acquired via a plurality of health sensors located throughout the employee's workstation, determining a health profile for the employee based at least in part on the collected health data, and serving, to an employee computer for display, health profile content comprising an avatar configured to communicate information relating to the health profile for the employee. The plurality of health sensors including at least one of biometric sensors and biomechanical sensors.

Disclosed herein are methods of treating a patient, comprising providing a compressible attenuation device that is moveable from a first, introduction configuration to a second, implanted configuration. The attenuation device is introduced into a treatment site. In one embodiment, the treatment site is the bladder. In another embodiment, the treatment site is the abdominal cavity. The volume of the attenuation devices changes in response to pressure changes in the treatment site and attenuates pressure changes in the bladder.

An ultrasonic probe includes a light irradiating portion configured to radiate light for generating ultrasonic waves from a light absorber, an ultrasonic transducing portion configured to transduce the ultrasonic waves to an electric signal, and a light guide member configured to introduce light from a light source to the light irradiating portion. A light irradiating region of the light irradiating portion is included within an ultrasonic receiving region of the ultrasonic transducing portion.

A method performed in a medical navigation system includes driving a transmitter at a first frequency and a second frequency to generate first and second electromagnetic fields, wherein the first and second frequencies are sufficiently low such that the first and second electromagnetic fields are frequency independent; receiving first and second distorted fields corresponding to the first and second electromagnetic fields, respectively, with each of at least two electromagnetic (EM) sensors attached to a surgical device; generating first and second signals in response to receiving the first and second distorted fields, respectively, using each of the at least two EM sensors; and determining a distortion in the first and second signals based at least on a distance between the at least two EM sensors and a difference between the first and second signals generated by each of the at least two EM sensors.

A device having an arterial pulse sensor that is adhered to the hypothenar region of a palm using an adhesive patch. The patch has an adhesive surface that is covered by a removable film with an outer portion and a central portion. Also disclosed is a method of detecting an arterial pulse by providing an arterial pulse sensor, placing the sensor on the hypothenar region of the palm of a hand, and receiving an arterial pulse signal from the sensor.

A collar for pet animals may have sensor elements remotely actuatable to measure vital signs of the animal (such as respiration, pulse, temperature and movement) and a processor that can interpret the results of multiple vital sign readings. A two way communication device alerts the pet owner, veterinarian or authorities. A veterinarian can remotely take a particular vital sign measurement when alerted. The sensor elements embedded in the collar's band has at least one elastic pin extending toward the animal's neck to gather data processed on the collar or remotely. To improve STN ratio, an elastic layer may absorb noise from friction due to movement of the animal's head. The collar may adjust the tightness of the band for taking vital sign readings. For example pump may injects air through a tubular compertment running along the circumference of the band. A safety mechanism may release the collar.