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Application of 20(R)-ginsenoside Rg3 in preparation of medicines for treating leucoderma

A ginsenoside and vitiligo technology, applied in the field of medicine, can solve the problems of loss of adrenal hormones, difficult to treat disease, abdominal pain, etc., and achieve the effects of improving melanin distribution, easy promotion, and quick effect.

Inactive Publication Date: 2014-06-11
富力
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In mild cases, the body will produce side effects such as acne, rosacea, glaucoma, skin streaks and atrophy, purpura, bacterial and fungal infections, etc. In severe cases, the original renal secretion function will be inhibited and atrophy, and the normal secretion of adrenal hormones will be lost. function, once the drug is stopped, the patient will experience a severe rebound effect, making the condition more difficult to treat
Immunomodulator treatment is likely to cause nausea, abdominal pain, loss of taste, and easy to rebound after drug withdrawal

Method used

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  • Application of 20(R)-ginsenoside Rg3 in preparation of medicines for treating leucoderma
  • Application of 20(R)-ginsenoside Rg3 in preparation of medicines for treating leucoderma
  • Application of 20(R)-ginsenoside Rg3 in preparation of medicines for treating leucoderma

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Embodiment 1 Rg3 cream

[0048] 1. Prepare raw materials according to the following ratio

[0049] 1) Prepare the raw materials of part A according to the ratio:

[0050]

[0051] 2) Prepare the raw materials of Part B according to the ratio as follows:

[0052]

[0053] 2. Mix the raw materials of parts A and B respectively under stirring, heat and keep them at 70°C. After stirring evenly, add the mixed raw materials of part B to the raw materials of part A while stirring while keeping the temperature at 70°C. After stirring evenly, add deionized water to 100%, and cool to room temperature.

Embodiment 2

[0054] Embodiment 2 Rg3 gel

[0055] 1. Prepare raw materials according to the following ratio

[0056]

[0057] 2. Add carbomer to deionized water, stir and swell, add ginsenoside Rg3, EDTA-Na2, essence, propylparaben, methylparaben, stir evenly, and use a mass percentage concentration of 10 % sodium hydroxide solution to adjust the pH of the mixed solution to 6 (pH 5-7 is also applicable to the present invention), stir evenly, and add deionized water to 100%.

Embodiment 3

[0058] Example 3 Rg3 plaster

[0059] 1. Prepare raw materials according to the following ratio

[0060]

[0061] 2, ginsenoside Rg3 is mixed with a small amount of water, then add EDTA-Na After dissolving, be that the pH of 10% sodium hydroxide solution regulation mixing solution is 6 (pH is that 5~7 is also applicable to the present invention) with mass percent concentration ), then add essence, propylparaben, and methylparaben under stirring state, mix well and add to acrylic resin paste base, add deionized water to 100%, mix well, and spread on the back Plaster made of lined non-woven fabric.

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PUM

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Abstract

The invention discloses a novel application of 20(R)-ginsenoside Rg3 in preparation of medicines for relieving or / and treating leucoderma. Tests show that the 20(R)-ginsenoside Rg3 is significant in treating effects for the leucoderma, quick in effectiveness, low in toxic and side effects, safe, efficient, stable, simple in preparation process, suitable for industrial production, and prone to popularization. The application provides a novel medicine source for preventing and treating the leucoderma and complications thereof.

Description

technical field [0001] The invention relates to the field of medicine, and relates to a medicine or health food for treating vitiligo, in particular to an application of extract components of traditional Chinese medicine ginseng in medicine or health food for alleviating and / or treating vitiligo. Background technique [0002] Vitiligo is a common multiple pigmented skin disease, which is characterized by localized or generalized depigmentation to form white spots, and is an acquired white patch formed by skin depigmentation. When vitiligo occurs, the white spots are mostly the size of a fingernail to a coin, which are nearly round or sub-round. There are also dot-like spots when onset. The boundary is more obvious, and some edges are surrounded by pigment bands. The number of early leukoplakia is variable, and may be limited to a certain part of the body or distributed in a certain nerve stage. According to statistics, the total prevalence rate in my country is 0.72‰, with ...

Claims

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Application Information

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IPC IPC(8): A61K31/704A61P17/00A23L1/29A23L33/00
Inventor 富力鲁明明王典仁王凯乾柳杨刘正贤鲁岐樊宏宇王硕
Owner 富力
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