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Method and apparatus for the photomodulation of living cells

A technology of light modulation and living tissue, applied in phototherapy, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve problems such as electric shock, eye injury, tissue damage, etc.

Inactive Publication Date: 2005-02-09
轻微波浪有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Even low-power lasers can cause at least eye injury or some tissue damage; and most lasers used in medical treatment present a risk of severe electric shock or death

Method used

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  • Method and apparatus for the photomodulation of living cells
  • Method and apparatus for the photomodulation of living cells
  • Method and apparatus for the photomodulation of living cells

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0130] Improvement of skin elasticity

[0131] Test the improvement of skin elasticity in three photoaged females before and after receiving the non-invasive method according to the present invention. waiting women. Subjective assessment of their cheeks was performed by specially trained medical personnel. The LED treatment consisted of irradiating a target area of ​​the patient's skin with LED light having a pulse width of 250 msec and a pulse interval of 250 msec for a total of 90 pulses. The entire face was treated eight times over a 12-week period using 590nm multicolor LEDs with intensities ranging from 1.05-2.05 μWatts. LEDs have a bandwidth of + / - 5-15nm and thus produce light with wavelengths ranging from 575nm to 605nm. Furthermore, this treatment maintains the skin temperature below the thermal damage threshold. The average improvement in skin elasticity is shown in Table 1.

[0132] skin elasticity

Embodiment 2

[0134] Wrinkle Reduction & Pulse Treatment

[0135] A blinded panel of expert scorers scored the overall improvement in visible skin wrinkles before and after viewing photographs of patients undergoing the non-invasive LILT ("Low Intensity Light Treatment") of the present invention.

[0136] Wrinkle reduction was tested on six photoaging women. The LED treatment consisted of irradiating a target area of ​​the patient's skin with LED light having a pulse width of 250 msec and a pulse interval of 250 msec for a period of 90 pulses. The entire face was treated eight times over a 12-week period using 590nm multicolor LEDs with intensities ranging from 1.0-2.0 μWatts. LEDs have a bandwidth of + / - 5-15nm and thus produce light with wavelengths ranging from 575nm to 605nm. Furthermore, this treatment maintains the skin temperature below the thermal damage threshold. The average reduction in visible wrinkles is shown in Table 2.

[0137] week / value

Embodiment 3

[0139] Wrinkle Reduction with CW Treatment

[0140] According to the method described in Example 2, a photoaging female was tested for wrinkle reduction. Her cheeks were rated by expert raters before and after a total of 200 s of continuous wave pulse treatment using 590 nm multicolor LEDs with intensities ranging from 1.05-2.05 μW. Eight treatments, evenly spaced, were applied to the patient's entire face over a 12-week period.

[0141] week / value

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PUM

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Abstract

The present invention relates to a system and method for the photomodulation of living tissue. When photomodulated, living tissue will exhibit bioactivation or bioinhibition according to the present invention and, when using the disclosed sources of narrowband multichromatic radiation can cause significant dermatologic advantages such as hair removal, hair growth stimulation, wrinkle reduction, acne reduction and scar removal, vitiligo, etc. The present invention has application to non-dermatological medical treatments including tumor growth inhibition, cell regeneration, the stimulation of tissue in organs, etc.

Description

[0001] related application [0002] This application is related to co-pending application serial number US09 / 759,094, filed January 13, 2001, which claims priority over provisional application serial number 60 / 176,175, filed January 13, 2000 rights, the entire contents of which are hereby incorporated by reference. field of invention [0003] The present invention relates to a method and apparatus for photomodulating living tissue, particularly tissue containing human cells, using narrowband, polychromatic electromagnetic radiation emitters. Exposure of living tissue to electromagnetic radiation having a carefully selected spectral wavelength-bandwidth, either for a continuous period of time or in pulses at a predetermined frequency, in which cells can be stimulated to initiate a genetically determined program or regenerative function, Or these same functions are suppressed. The new light modulation devices and methods can be used to control, stimulate, or inhibit cell growt...

Claims

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Application Information

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IPC IPC(8): A61B18/18A61B18/20A61K45/00A61N5/06A61P17/00A61P35/00
CPCA61B2018/00476A61N5/0616A61N2005/0652A61B18/203A61B2018/1807A61B2018/00458A61B2018/0047A61B2018/00452A61P17/00A61P35/00A61N2005/0642A61N2005/0627A61N5/06B82Y20/00
Inventor D·H·麦克丹尼尔
Owner 轻微波浪有限责任公司
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