658 results about "Caffeic acid" patented technology

The present invention relates to color stable personal care compositions that provide anti-oxidiation, moisturization, and / or prevent biodegradation in personal care formulations. These compositions contain erythorbic acid or a salt thereof, caffeic acid or a salt thereof, δ-gluconolactone, or a mixture thereof. The present invention further relates to methods of moisturizing skin with erythorbic acid or a salt thereof, or δ-gluconolactone. The present invention also relates to concentrates of active ingredients preloaded with a sufficient amount of an anti-oxidation, moisturizing and / or biodegradation prevention agent so that when it is diluted for use, the final formulation includes an anti-oxidation, moisturizing and / or biodegradation prevention effective amount of the anti-oxidation, moisturizing, and / or biodegradation prevention agent.

The present invention relates to a compound of the formula: R-AR—O—Y—R′Wherein R represents one or more members selected from H, alkoxy, benzyloxy, aldehyde, halogen, carboxylic acid, —NO2, —NH2, —NHCOCH3, and —NH—Y—R′, which is attached directly to AR or attached through an aliphatic chain. The carboxylic acid moiety in R includes but is not limited to the following carboxylic acids: benzoic acids, cinnamic acids, ferulic acid, caffeic acid, syringic acid, salicylic acid, vanillic acid, phenylacetic acids, phenylpropionic acids, and sinapinic acid. -AR—O— is a biologically active phenolic moiety comprising 1 to 6 substituted or unsubstituted aryl rings that are directly bonded to each other, fused together, or joined through a linking group. Y represents a member selected from: —COCH2O— (glycolic ester moiety) —COCH(CH3)O— (lactic ester moiety) —COCH2OCH2CH2O— (dioxanone ester moiety) —COCH2CH2CH2CH2CH2O— (caprolactone ester moiety) —CO(CH2)mO— where m is an integer between 2-4 and 6-24 inclusive —COCH2O(CH2CH2O)n— where n is an integer between 2 and 24, inclusive; and R′ is either hydrogen or a benzyl or an alkyl group, the alkyl group being either straight-chained or branched. The resultant functionalized phenolic compounds, used singly or in combinations, and their polymers have controllable degradation profiles, releasing the active component over a desired time range. The polymers are useful for biomaterials and biomedical devices, wherein said biologically active phenolic moiety is a residue of a phenolic compound.

The present invention relates to ascorbic acid single-phase solution compositions that provide enhanced stability, enhanced solubility and an enhanced photoprotective effect as compared to prior compositions. The compositions comprise L-ascorbic acid; a cinnamic acid derivative such as p-coumaric acid, ferulic acid, caffeic acid, sinapinic acid, a derivative thereof, and a combination thereof; a solvent comprising a glycol ether and an alkanediol; and water; the composition having a pH of no more than about 3.5. The compositions may also comprise a form of Vitamin E and are useful for treatment of radical-induced damage to a subject, particularly the skin of a subject.

The present invention relates to ascorbic acid single-phase solution compositions that provide enhanced stability, enhanced solubility and an enhanced photoprotective effect as compared to prior compositions. The compositions comprise L-ascorbic acid; a cinnamic acid derivative such as p-coumaric acid, ferulic acid, caffeic acid, sinapinic acid, a derivative thereof, and a combination thereof; a solvent comprising a glycol ether and an alkanediol; and water; the composition having a pH of no more than about 3.5. The compositions may also comprise a form of Vitamin E and are useful for treatment of radical-induced damage to a subject, particularly the skin of a subject.

A composite spot-removing liquid for removing senile plaque, chloasma, ephelides, etc and beautifying and whitening skin is prepared from 24 Chinese-medicinal materials including liquorice root, ginseng, mulberry bark, aloe, etc and 9 other raw materials including konjic acid, VA, caffeic acid, VB3, etc. Its preparing process is also disclosed.

The invention provides a method for simultaneously detecting main components of paeoniflorin, beta ecdysterone, laetrile, mulberroside A, caffeic acid, ferulic acid, salvianolic acid B, astragaloside, formononetin, cryptotanshinone and tanshinone IIA of a Naoxintong capsule in a plasma sample by a liquid chromatography-tandem mass spectrometry (HPLC-MS / MS). In a liquid chromatogram, a mobile phase consists of acetonitrile and a formic acid aqueous solution of which the volume fraction is 0.1%, and gradient elution is used. A mass spectrum uses a quick positive and negative ions switching and analyzing mode and an MRM (Multiple Reaction Monitoring) scanning manner. After the Naoxintong capsule is taken, the situations of the changes of the blood-medicine concentration of several kinds of main components in the plasma of a rat are detected at the same time. The methodological survey results indicate that the established method conforms to determination requirements on biological samples in a body; the method is good in sensitivity, high in specificity, stable, reliable, and suitable for detecting substances with lower contents.

The invention provides a medicinal composition containing caffeic acid ester and scutellarin. The composition is a composition for injection, and comprises, by weight, 45-95% of caffeic acid ester and 5-25% of scutellarin. The invention also provides application of the composition in preparation of drugs for treating cardiovascular and cerebrovascular diseases.

The invention discloses a preparation method of a chitosan derivative and application of the chitosan derivative to food preservation. According to the preparation method of the chitosan derivative, the chitosan derivative is obtained by performing reaction on chitosan powder in reaction liquid containing phenolic acid compounds and recombinant bacterial laccase at the temperature of 60 to 85 DEGC for 0.5 to 4 hours; and the phenolic acid compounds are selected from any one of ferulic acid, caffeic acid, chlorogenic acid, trihydroxybenzoic acid, gallic acid, catechinic acid, tannic acid and tea polyphenol. Compared with the chemical method, the preparation method of the chitosan derivative under catalyzed synthesis of bacterial laccase has the advantage of environmental friendliness and is a green production mode. The recombinant bacterial laccase has high heat stability, and catalytic reaction liquid can be reused repeatedly. The chitosan derivative has a good preservation effect invarious foods of fruit and vegetables, meat products, dairy products, grease products and the like.

The invention discloses a fluorescent probe and a preparation method thereof, and application in detecting superoxide anions. The structural formula of the fluorescent probe is disclosed in the specification. The preparation method comprises the following steps: in an inert gas protective atmosphere, dissolving melamine and caffeic acid in a DMF (N,N-dimethylformamide) and CH2Cl2 mixed solution, adding HOBT (N-hydroxybenzotriazole) and EDC.HCL (1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride), and stirring to react at room temperature for 8-16 hours; after the reaction, concentrating to remove the solvent, thereby obtaining the fluorescent probe crude product; and separating and purifying the fluorescent probe crude product with a silica gel thin-layer chromatographic sheet to obtain the fluorescent probe pure product. The fluorescent probe has the advantages of novel structure, high sensitivity, high selectivity and high light stability.