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3489results about How to "Inhibit aggregation" patented technology
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Lipid encapsulated interfering RNA
ActiveUS20060240093A1Inhibit aggregationMetabolism disorderMicroencapsulation basedLipid formationLipid particle
Owner:ARBUTUS BIOPHARMA CORPORAT ION
Lipid encapsulated interfering RNA
InactiveUS20050064595A1Inhibit aggregationMetabolism disorderMicroencapsulation basedLipid formationLipid particle
The present invention provides compositions and methods for silencing gene expression by delivering nucleic acid-lipid particles comprising a siRNA molecule to a cell.
Owner:PROTIVA BIOTHERAPEUTICS
Nanocrystal doped matrixes
ActiveUS20060068154A1Different propertyHigh refractive indexMaterial nanotechnologyMirrorsNanometreRefractive index matching
The present invention provides matrixes doped with semiconductor nanocrystals. In certain embodiments, the semiconductor nanocrystals have a size and composition such that they absorb or emit light at particular wavelengths. The nanocrystals can comprise ligands that allow for mixing with various matrix materials, including polymers, such that a minimal portion of light is scattered by the matrixes. The matrixes of the present invention can also be utilized in refractive index matching applications. In other embodiments, semiconductor nanocrystals are embedded within matrixes to form a nanocrystal density gradient, thereby creating an effective refractive index gradient. The matrixes of the present invention can also be used as filters and antireflective coatings on optical devices and as down-converting layers. The present invention also provides processes for producing matrixes comprising semiconductor nanocrystals.
Owner:SAMSUNG ELECTRONICS CO LTD
Nanocrystal doped matrixes
ActiveUS20070034833A1Good miscibilityInhibit aggregationMaterial nanotechnologyIndividual molecule manipulationAnti-reflective coatingSemiconductor nanocrystals
Matrixes doped with semiconductor nanocrystals are provided. In certain embodiments, the semiconductor nanocrystals have a size and composition such that they absorb or emit light at particular wavelengths. The nanocrystals can comprise ligands that allow for mixing with various matrix materials, including polymers, such that a minimal portion of light is scattered by the matrixes. The matrixes of the present invention can also be utilized in refractive index matching applications. In other embodiments, semiconductor nanocrystals are embedded within matrixes to form a nanocrystal density gradient, thereby creating an effective refractive index gradient. The matrixes of the present invention can also be used as filters and antireflective coatings on optical devices and as down-converting layers. Processes for producing matrixes comprising semiconductor nanocrystals are also provided. Nanostructures having high quantum efficiency, small size, and / or a narrow size distribution are also described, as are methods of producing indium phosphide nanostructures and core-shell nanostructures with Group II-VI shells.
Owner:SAMSUNG ELECTRONICS CO LTD
Nanocrystal doped matrixes
ActiveUS7645397B2Good miscibilityInhibit aggregationMaterial nanotechnologyIndividual molecule manipulationAnti-reflective coatingQuantum efficiency
Owner:SAMSUNG ELECTRONICS CO LTD
Functionalized matrixes for dispersion of nanostructures
ActiveUS20100276638A1High quantum yieldFacilitate device fabricationMaterial nanotechnologyGroup 4/14 element organic compoundsAnti-reflective coatingVolumetric Mass Density
Matrixes doped with semiconductor nanocrystals are provided. In certain embodiments, the semiconductor nanocrystals have a size and composition such that they absorb or emit light at particular wavelengths. The nanocrystals can comprise ligands that allow for mixing with various matrix materials, including polymers, such that a minimal portion of light is scattered by the matrixes. The matrixes are optionally formed from the ligands. The matrixes of the present invention can also be utilized in refractive index matching applications. In other embodiments, semiconductor nanocrystals are embedded within matrixes to form a nanocrystal density gradient, thereby creating an effective refractive index gradient. The matrixes of the present invention can also be used as filters and antireflective coatings on optical devices and as down-converting layers. Processes for producing matrixes comprising semiconductor nanocrystals are also provided. Nanostructures having high quantum efficiency, small size, and / or a narrow size distribution are also described, as are methods of producing indium phosphide nanostructures and core-shell nanostructures with Group II-VI shells.
Owner:NANOSYS INC
Biodegradable injectable implants containing glycolic acid
InactiveUS7314636B2Non-migratoryEasy to moveSolution deliveryPharmaceutical non-active ingredientsEmulsionGlycolic acid
Owner:MEDGRAFT MICROTECH
Pt complexes as phosphorescent emitters in the fabrication of organic light emitting diodes
ActiveUS7002013B1Inhibit aggregationReduction of phosphorescence radiative lifetimeGroup 4/14 element organic compoundsGroup 1/11 element organic compoundsLight-emitting diodeCoordination complex
A series of Pt(II) complexes having the following formula are disclosed: X1 and X2 independently are C or N, X1 can also locate at another position of the hexagonal ring, when X1 is N;R1 is H, C1–C8 alkyl, or C1–C4 perfluoroalkyl, R2 is H, R1 and R2 together are C4–C8 alkylene, or R1 and R2 together are bridged carbocyclic C4–C12 alkylene, when X2 is C;R1 is H, C1–C8 alkyl, or C1–C4 perfluoroalkyl, and R2 is omitted, when X2 is N;R7 is H or methyl, and R8 is omitted, when X1 is N;R7 is H or methyl, R8 is H or methyl, or R7 and R8 together are when X1 is C.
Owner:SAMSUNG DISPLAY CO LTD
Functionalized matrices for dispersion of nanostructures
ActiveUS8283412B2Good miscibilityInhibit aggregationMaterial nanotechnologyGroup 4/14 element organic compoundsAnti-reflective coatingSemiconductor nanocrystals
Owner:SHOEI CHEM IND CO LTD
Magnetic recording medium and coating composition for magnetic recording medium
ActiveUS20160093321A1Increased durabilitySmall particle sizeInorganic material magnetismRecord information storageHydrogen atomMagnetic layer
The magnetic recording medium comprises a magnetic layer comprising ferromagnetic powder and binder on a nonmagnetic support, and further comprises a compound denoted by Formula (1):wherein, in Formula (1), X denotes —O—, —S—, or NR1—; each of R and R1 independently denotes a hydrogen atom or a monovalent substituent; L denotes a divalent connecting group; Z denotes a partial structure of valence n comprising at least one group selected from the group consisting of carboxyl groups and carboxylate groups; m denotes an integer of greater than or equal to 2, and n denotes an integer of greater than or equal to 1.
Owner:FUJIFILM CORP
Magnetic recording medium and coating composition for magnetic recording medium
InactiveUS20140374645A1Good dispersionSmall particle sizeInorganic material magnetismRecord information storagePolyesterNon magnetic
An aspect of the present invention relates to a magnetic recording medium comprising a magnetic layer comprising ferromagnetic powder and binder on a nonmagnetic support, wherein an average particle size of the ferromagnetic powder is equal to or less than 50 nm, the magnetic layer further comprises a compound, and the compound comprises at least one polyalkyleneimine chain and at least one polyester chain, with a proportion in the compound accounted for by the polyalkyleneimine chain being less than 5.0 weight percent and a number average molecular weight of the polyalkyleneimine chain ranging from 300 to 3,000.
Owner:FUJIFILM CORP
Superficially porous materials comprising a substantially nonporous core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations
InactiveUS20130112605A1Prevent fine generationInhibit aggregationIon-exchanger regenerationPretreated surfacesChromatographic separationHybrid material
Novel chromatographic materials for chromatographic separations, columns, kits, and methods for preparation and separations with a superficially porous material comprising a substantially nonporous core and one or more layers of a porous shell material surrounding the core. The material of the invention is comprised of superficially porous particles and a narrow particle size distrution. The material of the invention is comprised of a superficially porous monolith, the substantially nonporous core material is silica; silica coated with an inorganic / organic hybrid surrounding material; a magnetic core material; a magnetic core material coated with silica; a high thermal conductivity core material; a high thermal conductivity core material coated with silica; a composite material; an inorganic / organic hybrid surrounding material; a composite material coated with silica; a magnetic core material coated with an inorganic / organic hybrid surrounding material; or a high thermal conductivity core material coated with an inorganic / organic hybrid surrounding material.
Owner:WATERS TECH CORP
Porous sintered metal-containing materials
InactiveUS20060211802A1Adversely affecting the physical and/or chemical stabilityInhibit aggregationAdditive manufacturingTransportation and packagingSolvent freeMetallic materials
A process for manufacturing a porous metal-containing material is provided. For example, a composition is provided comprising particles dispersed in at least one solvent, the particles comprising at least one polymer material and at least one metal-based compound. The solvent can be substantially removed from the composition, and the polymer material can be substantially decomposed, thereby converting the solvent-free particles into a porous metal-containing material. In addition, metal-containing materials produced in accordance with the above process and their use in implantable medical devices can be provided.
Owner:CINVENTION AG
Metal Nanoparticle, Metal Nanoparticle Colloid, Method for Storing Metal Nanoparticle Colloid, and Metal Coating Film
InactiveUS20090029148A1Easily produceHighly conductiveMaterial nanotechnologyConductive materialConductive coatingOrganic acid
The object of the present invention is provide a metal nanoparticle which has a nano-sized average diameter while being highly stable as a particle, and a method for producing such metal nanoparticle. Particularly provides a metal nanoparticle having characteristics such as particle diameter and particle size distribution suitable for forming a conductive coating layer, and a method for producing such metal nanoparticle. The metal nanoparticle of the present invention is characterized in that it is obtained by reacting a reducing agent act on a solution containing an organic acid metal salt and an amine.
Owner:NIPPON SHOKUBAI CO LTD
Copper bismuth catalyst and preparation method thereof
ActiveCN102658158AImprove wear performanceExtended service lifeOrganic compound preparationHydroxy compound preparationCooking & bakingAlcohol
The invention relates to a copper bismuth catalyst for combining chemically into 1, 4-butynediol with formaldehyde and ethyne and a preparation method thereof. The preparation method comprises the following steps of: preparing mixed solution which contains copper salt, bismuth salt, magnesium salt and dispersant; dropping alcoholic solution with an organic silicon source into the mixed solution; adjusting a pH value of the mixed solution with alkaline solution to obtain mixed precipitate; and further aging, washing, drying and baking in inert atmosphere to obtain the copper bismuth catalyst with C-MgO-SiO2 a carrier, in the catalyst, the content of CuO accounts for 25-50 weight percent, and the content of Bi2O3 accounts for 2-6 weight percent. The catalyst is applied in a reaction of combining chemically into 1, 4-butynediol with formaldehyde and ethyne, and has high catalytic activity and high selectivity.
Owner:SHANXI UNIV
TRANSDUCIBLE DELIVERY OF siRNA BY dsRNA BINDING DOMAIN FUSIONS TO PTD/CPPS
ActiveUS20090093026A1Inhibit aggregationInduces macropinocytosisFusion with RNA-binding domainSpecial deliveryDiseaseProtein transduction domain
The disclosure provides fusion polypeptides and constructs useful in delivering anionically charged nucleic acid molecules including diagnostics and therapeutics to a cell or subject. The fusion constructs include a protein transduction domain and a nucleic acid binding domain, or a protein transduction domain and a nucleic acid that is coated with one or more nucleic acid binding domains sufficient to neutralize an anionic charge on the nucleic acid. Also provided are methods of treating disease and disorders such as cell proliferative disorders.
Owner:RGT UNIV OF CALIFORNIA
Cationic oil-in-water emulsions
ActiveUS20120156251A1Promote particle formationImprove skin toneAntibacterial agentsOrganic active ingredientsAntigenOil emulsion
This invention generally relates to cationic oil-in-water emulsions that can be used to deliver negatively charged molecules, such as an RNA molecule. The emulsion particles comprise an oil core and a cationic lipid. The cationic lipid can interact with the negatively charged molecule thereby anchoring the molecule to the emulsion particles. The cationic emulsions described herein are particularly suitable for delivering nucleic acid molecules (such as an RNA molecule encoding an antigen) to cells and formulating nucleic acid-based vaccines.
Owner:GLAXOSMITHKLINE BIOLOGICALS SA
Bioprocess for the generation of cells from spheroid-forming cells
InactiveUS20030119107A1Inhibit aggregationCell culture supports/coatingTissue/virus culture apparatusHigh cellVolumetric Mass Density
The present inventors identified aggregation of embryonic stem cells and embryoid bodies (EBs) as the cause of the difficulty in generating large numbers of the embryonic stem cells (ES) cell-derived tissues. To counter this, the invention provides a novel bioprocess where aggregation of spheroid forming cells, such as embryonic stem cells and spheroids, such as EBs is controlled, such as by encapsulation of within a matrix. As a result, EBs can be generated with high efficiency and cultured in high cell density, well-mixed systems. Well-mixed conditions facilitate measurement and control of the bulk media conditions and allow for the use of scalable bioreactor systems for clinical production of tissue. Therefore, the invention enables generation of ES cell-derived tissue on a clinical scale. The invention is also applicable to any spheroid-forming cells and other types of pluripotent cells.
Owner:CARDION AG
Non-inclusion cyclodextrin complexes
InactiveUS20030109492A1Enhance cyclodextrin solubilizationImprove complexation efficiencyBiocideSugar derivativesWater solubleBULK ACTIVE INGREDIENT
The invention provides a number of methods for enhancing the aqueous solubility of an active ingredient which is insoluble or sparingly soluble in water. In one preferred embodiment, solubilization of the active ingredient is enhanced by combining it with beta-cyclodextrin in an aqueous complexation medium comprising beta-cyclodextrin and a negatively- or positively-charged compound which forms an inclusion or non-inclusion complex with beta-cyclodextrin and its inclusion complexes.
Owner:DECODE GENETICS EHF
Non-inclusion cyclodextrin complexes
InactiveUS7115586B2Improve stabilityInhibit aggregationBiocideSugar derivativesWater solubleBULK ACTIVE INGREDIENT
The invention provides a number of methods for enhancing the aqueous solubility of an active ingredient which is insoluble or sparingly soluble in water. In one preferred embodiment, solubilization of the active ingredient is enhanced by combining it with β-cyclodextrin in an aqueous complexation medium comprising β-cyclodextrin and a negatively- or positively-charged compound which forms an inclusion or non-inclusion complex with β-cyclodextrin and its inclusion complexes.
Owner:DECODE GENETICS EHF
Ultra-small LED electrode assembly and method for manufacturing same
ActiveUS20160148911A1Light extraction efficiency can be improvedImprove extraction efficiencyFinal product manufacturePrinted circuit aspectsEngineeringLead electrode
Provided are a nano-scale LED assembly and a method for manufacturing the same. First, a nano-scale LED device that is independently manufactured may be aligned and connected to two electrodes different from each other to solve a limitation in which a nano-scale LED device having a nano unit is coupled to two electrodes different from each other in a stand-up state. Also, since the LED device and the electrodes are disposed on the same plane, light extraction efficiency of the LED device may be improved. Furthermore, the number of nano-scale LED devices may be adjusted. Second, since the nano-scale LED device does not stand up to be three-dimensionally coupled to upper and lower electrodes, but lies to be coupled to two electrodes different from each other on the same plane, the light extraction efficiency may be very improved. Also, since a separate layer is formed on a surface of the LED device to prevent the LED device and the electrode from being electrically short-circuited, defects of the LED electrode assembly may be minimized. Also, in preparation for the occurrence of the very rare defects of the LED device, the plurality of LED devices may be connected to the electrode to maintain the original function of the nano-scale LED electrode assembly.
Owner:SAMSUNG DISPLAY CO LTD
TiO2 material and the coating methods thereof
ActiveUS7144840B2Reduce moistureInhibit aggregationMaterial nanotechnologyLiquid surface applicatorsAir purificationTitanium dioxide
The present invention relates to a titanium dioxide material for coating on a substrate and method of making the same. The coated material is resistant to delamination and can be used for air-purification purposes.
Owner:THE HONG KONG UNIV OF SCI & TECH
Method for preparing large-scale graphene through supercritical carbon dioxide exfoliation
ActiveCN102515155AReduce forceReduce the number of layersGrapheneBulk chemical productionMicrometerGraphite
The invention relates to a method for preparing large-scale graphene through supercritical carbon dioxide exfoliation. Supercritical carbon dioxide is adopted as an exfoliant, a surfactant is adopted as a dispersant, graphite powder and the dispersant are put in an autoclave, the carbon dioxide is pumped in the autoclave and circularly flows in a supercritical state, and then the pressure is reduced quickly to be normal pressure; the process is repeated so that the materials undergo pressure increment and pressure reduction several times; and the layers of the graphene is controlled by controlling the times of pressure increment and pressure reduction, so as to prepare the large scale graphene. Compared with the prior art, the invention has the advantages as follows: large-scale (hundreds of micrometers) high-quality graphene can be prepared; the method belongs to physical exfoliation, the treatment conditions are mild, and the quality of the graphene cannot be damaged; besides, the carbon dioxide used in the method is nontoxic, cheap and easy to obtain, and the technology is simple.
Owner:上海利物盛纳米科技有限公司
Back pressure adjustment apparatus for liquid ejection head
InactiveUS20080231650A1Improve degassing effectAdjustable temperatureOther printing apparatusLiquid jetEngineering
The back pressure adjustment apparatus for a liquid ejection head has: a container having a liquid accommodating chamber which is connected to the liquid ejection head and accommodates liquid to be supplied to the liquid ejection head, and a gas accommodating chamber which accommodates gas; a movable film which separates the liquid accommodating chamber and the gas accommodating chamber, and forms a portion of whole walls of the liquid accommodating chamber; and a pressure adjustment device which causes all or a portion of the movable film to deform so as to adjust pressure of the liquid accommodated in the liquid accommodating chamber.
Owner:FUJIFILM CORP
Conductive particles and method and device for manufacturing the same, anisotropic conductive adhesive and conductive connection structure, and electronic circuit components and method of manufacturing the same
InactiveUS6906427B2Efficient executionInhibit aggregationElectrolysis componentsSemiconductor/solid-state device detailsAnisotropic conductive adhesiveElectrical connection
An electrical connection is formed by using a double laminated conductive fine particle provided with a conductive metal layer on the surface of a spherical elastic base particle by electroless plating and electroplating and a layer of a low-melting-point metal on the surface of the conductive metal layer and wherein the conductive metal layer comprises a plurality of metal layers.
Owner:SEKISUI CHEM CO LTD
Method for preparing graphene oxide/white carbon black/rubber nanocomposite material
A method for preparing a graphene oxide / white carbon black / rubber nanocomposite material is described. The prepared graphene oxide / white carbon black / rubber nanocomposite material contains nanoscale graphene oxide and white carbon black that are highly dispersed. The nanocomposite material has a relatively high modulus, excellent wear resistance and tear resistance, a relatively low rolling resistance, and at the same time has a low air-permeability and excellent self-healing capability.
Owner:BEIJING UNIV OF CHEM TECH
Hepatocyte growth factor for treatment of diabetes
InactiveUS6472366B2Lower blood sugar levelsLower Level RequirementsBiocidePeptide/protein ingredientsCvd riskBULK ACTIVE INGREDIENT
The present invention provides a therapeutic agent for treatment of diabetes and hyperlipemia, especially a therapeutic agent for treatment of type II diabetes mellitus, which comprises as the active ingredient a neurotrophic factor such as BDNF (brain-derived neurotrophic factor), ligands of trkB or trkC receptors, NGF, NT-3, NT-4 / 5, CNTF, GDNF, HGF, etc. Different from conventional oral hypoglycemic agents being mainly used in the treatment of type II diabetes mellitus, the agent of the present invention exhibit blood lipid regulating effects and body fat accumulation regulating effects, in addition to the blood glucose regulating effects. Thus, the agent of the present invention are novel, and can reduce the risk factors in diabetes accompanied by hyperlipemia or obesity, without using any other agent.
Owner:SUMITOMO PHARMA CO LTD
Light emitting apparatus
ActiveUS20050168992A1Avoid it happening againImprove bindingDischarge tube luminescnet screensLamp detailsLight reflectionReflective layer
A light emitting apparatus has: a support; a wiring layer that is formed on the support; and an LED element that is flip-chip mounted on the wiring layer formed on the support. The wiring layer has: a conductive layer that is formed on the support and is electrically connected to an electrode of the LED element; and a reflection layer that is formed on the conductive layer that has a light reflection property to allow a radiated light from the LED element to be reflected thereon. The reflection layer is of a material that generates no intermetallic compound to a material of the conductive layer.
Owner:TOYODA GOSEI CO LTD
Antibody based reagents that specifically recognize toxic oligomeric forms of tau
ActiveUS20150266947A1Reduce formation rateInhibit aggregationNervous disorderMicrobiological testing/measurementAntibody fragmentsBiochemistry
Owner:ARIZONA STATE UNIVERSITY +1
Three-dimensional conductive patterns and inks for making same
InactiveUS20150366073A1Inhibit aggregationGood dispersionAdditive manufacturing apparatusTransportation and packagingPolymer scienceOligomer
The invention generally relates to polymerizable conductive ink formulations comprising at least one metal source, at least one monomer and / or oligomer and a polymerization initiator, and uses thereof for printing three-dimensional functional structures. In particular a method of fabricating a three-dimensional conductive pattern on a substrate is disclosed, the method comprising: a) forming a pattern on a surface region of a substrate by using an ink comprising at least one metal source, at least one liquid polymerizable monomer and / or oligomer, and at least one polymerization initiator; b) polymerizing at least a portion of said liquid monomer and / or oligomer; c) rendering the metal source a continuous percolation path for electrical conductivity (sintering); d) repeating steps (a), (b) and optionally (c) to obtain a three-dimensional conductive pattern.
Owner:YISSUM RES DEV CO OF THE HEBREWUNIVERSITY OF JERUSALEM LTD
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