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354 results about "Fat accumulation" patented technology

Fat accumulation can occur in the abdomen, breasts, neck and shoulders. It can occur in both men and women. Small bumps or collections of fat, called lipomas, can occur under the skin in other parts of the body including the pubis.

Compositions and methods for modulating metabolism

InactiveUS20130252331A1Reduce probabilityTreating and preventing obesityBiocideOrganic chemistryDiseaseBRD4
The invention provides compositions comprising an effective amount of an agent that inhibits a BET protein (e.g., Brd2, Brd3, Brd4), and methods of using such compositions for treating or preventing metabolic syndrome, obesity, type II diabetes, insulin resistance, and related disorders characterized by undesirable alterations in metabolism or fat accumulation.
Owner:THE BRIGHAM & WOMEN S HOSPITAL INC +1

Hepatocyte growth factor for treatment of diabetes

The present invention provides a therapeutic agent for treatment of diabetes and hyperlipemia, especially a therapeutic agent for treatment of type II diabetes mellitus, which comprises as the active ingredient a neurotrophic factor such as BDNF (brain-derived neurotrophic factor), ligands of trkB or trkC receptors, NGF, NT-3, NT-4 / 5, CNTF, GDNF, HGF, etc. Different from conventional oral hypoglycemic agents being mainly used in the treatment of type II diabetes mellitus, the agent of the present invention exhibit blood lipid regulating effects and body fat accumulation regulating effects, in addition to the blood glucose regulating effects. Thus, the agent of the present invention are novel, and can reduce the risk factors in diabetes accompanied by hyperlipemia or obesity, without using any other agent.
Owner:SUMITOMO PHARMA CO LTD

Dietary fiber fruit and vegetable meal replacement powder capable of adjusting in-vivo nutrient balance and inhibiting in-vivo fat accumulation and preparation method

The invention relates to soluble dietary fiber fruit and vegetable meal replacement powder and a preparation method thereof, in particular to dietary fiber fruit and vegetable meal replacement powder capable of adjusting in-vivo nutrient balance and inhibiting in-vivo fat accumulation and a preparation method, and belongs to the technical field of nutrition and health-care food. The dietary fiber fruit and vegetable meal replacement powder is characterized by consisting of the following components in percentage by weight: 10 to 60 percent of refined konjac powder, 15 to 50 percent of soybean dietary fiber powder, 5 to 15 percent of polydextrose, 10 to 20 percent of coix seed powder, 10 to 20 percent of yam powder, 0 to 2 percent of seasoning, and 0 to 5 percent of vitamin B. The soluble dietary fiber fruit and vegetable meal replacement powder prepared by the method is fine and smooth in mouthfeel, good in brew-up performance and rich in nutrition, and has multiple health-care effects of clearing intestines and stomach, reducing three highs, preventing obesity, whitening and moistening skin and the like.
Owner:湖北汇丰医药科技有限公司

Remedies for diabetes

The present invention provides a therapeutic agent for treatment of diabetes and hyperlipemia, especially a therapeutic agent for treatment of type II diabetes mellitus, which comprises as the active ingredient a neurotrophic factor such as BDNF (brain-derived neurotrophic factor), ligands of trkB or trkC receptors, NGF, NT-3, NT-4 / 5, CNTF, GDNF, HGF, etc. Different from conventional oral hypoglycemic agents being mainly used in the treatment of type II diabetes mellitus, the agent of the present invention exhibit blood lipid regulating effects and body fat accumulation regulating effects, in addition to the blood glucose regulating effects. Thus, the agent of the present invention are novel, and can reduce the risk factors in diabetes accompanied by hyperlipemia or obesity, without using any other agent.
Owner:SUMITOMO DAINIPPON PHARMA CO LTD

A method for improving the biomass and oil accumulation of oleaginous microalgae using a two-stage culture strategy of admixture and nitrogen-enrichment-nitrogen deficiency

The invention discloses a method for improving biomass and oil accumulation of oleaginous microalgae Scenedesmusdimorphus by adopting a two-stage culture strategy of co-culture and nitrogen deficiency, and belongs to the technical field of microalgae bioenergy. The invention adds a certain concentration of organic carbon source glucose to the autotrophic culture medium, and carries out concurrent culture with CO2 as the autotrophic carbon source. At the same time, under nitrogen-enriched conditions, after high-density culture of microalgae to a stable stage, the algae liquid is transferred to a nitrogen-deficient medium to continue the culture. When the glucose concentration is 1.2-5.4g/L, the initial pH is 7, and the culture time is 14-16 days, the biomass of microalgae can reach up to 4.5g/L, which is 2.57 times the biomass under autotrophic conditions; nitrogen deficiency Under these conditions, the total lipid content of microalgae reaches the highest of 29.62%, which is 1.6 times that of the nitrogen-enriched stage. By adding organic carbon sources and providing nitrogen-deficient conditions for two-stage culture, the biomass of microalgae can be effectively increased and oil accumulation can be promoted, which is of great significance to the research of large-scale production of bioenergy by microalgae.
Owner:JIANGNAN UNIV

Isoflavone compositions for reducing accumulation of body fat in male mammals, and methods for their use

Edible compositions useful for weight management in male animals are disclosed. The compositions comprise one or more isoflavones or isoflavone metabolites and are particularly useful for reducing or preventing the accumulation of body fat. Also disclosed are methods useful for weight management in an animal utilizing compositions comprising one or more isoflavones. The compositions and methods are particularly useful for the reduction or prevention of body fat accumulation during periods of excess caloric intake, and preferably have a sparing effect on lean body mass.
Owner:SOC DES PROD NESTLE SA

Chinese herbal feed additive for weight increase and beef quality improvement at late beef cattle fattening stage

The present invention discloses a Chinese herbal feed additive for weight increase and beef quality improvement at a late beef cattle fattening stage. The Chinese herbal feed additive comprises the following traditional Chinese medicines, by weight, 25-35 parts of pine needle powder, 5-15 parts of hawthorn, 5-15 parts of medicated leaven, 5-15 parts of swordlike atractylodes rhizome, 5-15 parts of cultivated purple perilla fruit, 3-7 parts of cyrtomium rhizome, 15-25 parts of glossy privet fruit, and 3-7 parts of licorice root. According to the present invention, various components are crushed, screened through a 60 mesh sieve, and sub-packaged according to 150 g / bag to provide a spare use, wherein the time of slaughter of beef cattle is the late fattening stage, and per beef cattle is fed with 150 g of the Chinese herbal feed additive per day; and with the Chinese herbal feed additive, the cattle can have characteristics of plump beef and fat accumulation at the late beef cattle fattening stage so as to increase beef cattle body weight, improve beef quality, and increase benefits.
Owner:HENAN UNIV OF SCI & TECH

Oil or fat composition

InactiveUS20040191391A1Low in body fat accumulationEqual cooking propertyBiocideOrganic active ingredientsFlavorTriglyceride
There is provided an oil or fat composition composed chiefly of triglycerides wherein the rate of middle-chain fatty acids in all the fatty acids composing the oil or fat composition is 5 to 23% by mass and the rate of triglycerides having two middle-chain fatty acid residues in the molecule in all the triglycerides is 1 to 20% by mass. The oil or fat composition is low in body fat accumulation, has equal cooking properties with conventional edible oils and has good flavor and high safety.
Owner:THE NISSHIN OILLIO GRP LTD

Application of composite high-fat forage to construct non-alcoholic fatty liver disease rat model

The invention belongs to the field of animal experiment models, and discloses application of a composite high-fat forage to construct a non-alcoholic fatty liver disease rat model. The high-fat forage is composed of the following raw materials in percent by mass: 77.5% of a rat basic forage, 10% of egg, 10% of coconut oil, 2% of cholesterol, 0.5% of bile salt, and 500mg / kg / d of sodium valproate calculated according to the rat weight. After 8 weeks, rats all have typical non-alcoholic fatty live symptoms, and liver has a lot of fat accumulation along with inflammatory cell infiltration. The model establishing time is short, the success rate is high, and the composite high-fat forage is applicable to pathogenesis research induced by high-fat-diet combined medicines with liver-toxicity side effect, screening of related control measures and efficacy evaluation of treatment medicines.
Owner:NANJING GENERAL HOSPITAL NANJING MILLITARY COMMAND P L A +1

Method for open-type culture of microalgae

The invention discloses a method for open-type culture of microalgae, which comprises the following contents: CO2 is supplied into an illumination open-type bioreactor which contains microalgae and a microalga culture medium for the growth of microalgae, wherein the CO2 is supplied by a method which is to mix a CO2-containing gas with a liquid phase by using a gas-liquid mixed conveying device, perform gas-liquid separation in a gas-liquid separator, and deliver a CO2-dissolving liquid phase obtained after gas-liquid separation to the illumination open-type bioreactor to supply the CO2 required by the growth of the microalgae. Compared with the prior method, the method solves the problem of low CO2 utilization rate caused by thinness of a liquid layer in the conventional open-type microalga culture system, improves the fat accumulation capacity in a microalga culture process, improves CO2 utilization rate and simplifies a culture device.
Owner:CHINA PETROLEUM & CHEM CORP +1

Facial pack and bathing compositions based on Hwangto (Korean loess) and preparation thereof

Disclosed are a facial pack composition and a bathing composition based on loess, and methods for preparing the same. The bathing composition makes a user feel refreshed, prevents arteriosclerosis and fat accumulation in human bodies, is useful for the treatment of maturating diseases such as dermatophytosis and dermatitis and stimulates metabolism and blood circulation system of the human body. Additionally, the facial pack includes loess having a fine particle size sufficient to avoid skin irritation and thus does not adversely affect the skin even if the user uses the pack everyday. The loess is pretreated by a unique aging method and selected additives, so that the far infrared ray-emitting effect of the loess can be maximized. Therefore, it provides skin health-aid and cosmetic effects. Further, the bathing composition is an environmental-friendly composition because the loess-containing water discharged after bathing flows into a draining path, thereby purifying a contaminated river and recovering contaminated soil.
Owner:PARK JANG YONG

Compound protein powder for resisting age-related sarcopenia, and preparation methods thereof

The invention discloses compound protein powder for resisting age-related sarcopenia, and preparation methods thereof. The compound protein powder comprises, by weight, 60-80 parts of whey protein, 10-30 parts of collagen peptide, 1-5 parts of amino acids, 0.1-0.25 part of vitamin, 0.005-0.02 part of carotene, 5-20 parts of MCT and 0.01-0.05 part of creatine. The compound protein powder may also comprise 3-20 parts of lecithin. The preparation methods comprise a dry method and a wet method. The collagen peptide, the whey protein and the amino acids are mixed; MCT and vitamin are mixed; vitamin is mixed with carotene, and creatine; and then the above materials are mixed together. The compound protein powder can guarantee absorption of human body protein and promote growth of muscle, without aggravating age-related fat accumulation, and can play a good delay effect for age-related sarcopenia. The preparation process is stable; quality is controllable; and the compound protein powder can be produced in large scale.
Owner:HANGZHOU NUTRITION BIOTECH

Oil/fat composition

Provided is an oil / fat composition comprising 10.1 to 94.9 wt. % of a triglyceride, 0.1 to 30 wt. % of a monoglyceride and 5 to 59.9 wt. % of a diglyceride which has, as a fatty acid constituent thereof, 15 to 90 wt. % of an ω3-unsaturated fatty acid having less than 20 carbon atoms. The oil / fat composition of the present invention has excellent heat stability, has body-fat-accumulation resisting action, visceral-fat-accumulation resisting action, blood-sugar-level lowering action, insulin resistance improving action and leptin lowering action and is useful for, as well as pharmaceuticals, preventive or remedial food for diabetes or obesity, and feed.
Owner:KAO CORP

Pastry moon cake and preparation method thereof

The present invention aims to provide a pastry moon cake and a preparation method thereof. The preparation method includes water-oiled dough production, pastry production, a pastry filling process, filling production, raw cake production and a baking process, wherein warm water is used in the production of water-oiled dough, and the temperature of the warm water is controlled at 40-80 DEG C, and green tea powder is added in the production process of fillings. Beneficial effects of the pastry moon cake: grease contents and sugar contents in moon cakes are reduced by using vegetable oil instead of traditional animal oil and using xylitol instead of sucrose in the moon cake production process, so that the pastry moon cake can inhibit the increase of blood sugar and fat accumulation in the human body, and is suitable for diabetics and the elderly to eat; and the introduction of green tea powder into the traditional five-kernel fillings makes the pastry moon cake light in taste and delicate in fragrance, healthy and nutritional.
Owner:TIANJIN YOUHAO INTERCONNECTION TECH CO LTD

Sea cucumber saponin, preparation method thereof and application thereof in food or medicine

The invention discloses a sea cucumber saponin, a preparation method thereof and the application thereof in food or medicines. A sea cucumber saponin mixture comprises multiple sea cucumber alkyl-type triterpenoid saponins. Preferentially, the sea cucumber saponin mixture comprises holothurin A and / or echinoside A. The sea cucumber saponin mixture can also comprise one or more in holothurin A, holothurin B, echinoside A, echinoside B, 24-dehydroechinoside A and stichoposide E. The sea cucumber saponin can be applied to preparing weight-losing food or medicines, and animal experimental resultsshow that the sea cucumber saponin can be used for remarkably inhibiting weight increment and reducing internal fat accumulation so as to realize a good weight-losing effect. The preparation method of the sea cucumber saponin is low in cost, simpler in steps and less in the pollution of organic solvents on the environment; and through animal experiments, the prepared sea cucumber saponin is proved to have a good weight-losing effect so as to be used for developing safe and effective weight-losing food or medicines.
Owner:OCEAN UNIV OF CHINA

Method for high-efficiency culture of microalgae

ActiveCN102311922AAchieve airlift stirring actionOvercoming recharge CO <sub>2<</sub> Unicellular algaeMicroorganism based processesMicroorganismPre treatment
The invention discloses a method for high-efficiency culture of microalgae, which comprises the following contents: introducing a gas containing CO2 into an illumination airlift bioreactor which contains microalgae and a microalga culture medium to realize airlift, supplying CO2 and resolving O2, wherein the gas containing CO2 is from tail gas of microorganism fermentation, and the tail gas is introduced into the illumination airlift bioreactor after passing through a conveying pretreatment device. Compared with the prior art, the method disclosed by the invention has the advantages of improving the fat accumulation capacity of the microalgae in a microalga culture process, improving utilization rate of CO2, improving O2 resolution capacity, simplifying the culture device and the like.
Owner:CHINA PETROLEUM & CHEM CORP +1

Gene for adjusting plant luminous energy application and oil and fat accumulation and application thereof

Belonging to the field of gene engineering, the invention relates to an AP2 / EREBP transcription factor bNwrI1 gene and an application thereof in adjusting plant seed photosynthesis and oil and fat anabolism. The transcription factor is extracted from brassica napus and is one of the following polypeptides: a polypeptide provided with an amino acid sequence as SEQ ID NO:2 indicates, a polypeptide which is formed with the amino acid sequence replaced, deleted and added by one or more than one amino acid residue and provided with the amino acid sequence and a polypeptide with functions thereof derivating from the polypeptide provided with the amino acid sequence. The transcription factor and coding genes thereof enjoy extensive application value in plant culturing field and can enable the plant to coordinately regulate photosynthesis and fatty acid anabolism, improves seed photosynthesis and oil and fat accumulation capacity, thus improving plant yield and oil content as well as correlated characteristics.
Owner:ZHEJIANG ACADEMY OF AGRICULTURE SCIENCES

Lactobacillus plantarum Lp90, and screening method and application thereof

The invention relates to lactobacillus plantarum Lp90, and a screening method and application thereof, in particular to lactobacillus plantarum with a function of inhibiting fat accumulation. The lactobacillus plantarum is named Lp90 and is preserved in the common microbiology center of the Chinese microbial strain preservation management committee, and the preservation number is CGMCC No.10453. The lactobacillus plantarum is obtained through an in-vitro nematode screening model, the fat accumulation of nematode can be reduced by 60 percent, and the lactobacillus plantarum has a potential function of preventing obesity and can be added into food, health care products or medicines as probiotics. Meanwhile, the invention provides the screening method namely a nematode culture model, and fat accumulation data of the nematode can be qualitatively and quantitatively detected, so that strains with the function of inhibiting the fat accumulation can be conveniently and quickly screened, the accuracy rate is high, and the economic cost is lower.
Owner:JIANGSU WECARE BIOTECHNOLOGY CO LTD

Composition and method for treating nonalcoholic steatohepatitis

Nonalcoholic steatohepatitis (NASH) is a disease of the liver characterized by inflammation and damage to the liver cells. Typically, steatohepatitis involves inflammation of the liver related to fat accumulation, and mimics alcoholic hepatitis but is observed in patients who seldom or never consume alcohol. Nonalcoholic steatohepatitis can lead to serious liver damage, and ultimately cirrhosis. The present invention provides methods and compositions useful for the treatment or alleviation of nonalcoholic steatohepatitis and the pharmaceutical formulations for their administration to a human. Specifically, compositions comprised of lecithin, antioxidants and vitamin B complex are administered parenterally, most preferably by oral administration. Specific therapeutic formulations include admixtures of these compounds and specific dosage formulations include daily oral administrations of these compounds in tablet or powder forms.
Owner:VIVA AMERICA MARKETING

Lactobacillus reuteri with weight reducing function and application of lactobacillus reuteri

The invention relates to the field of microorganisms and discloses lactobacillus reuteri with a weight reducing function and an application of the lactobacillus reuteri. The lactobacillus reuteri 1723strain is separated from butter collected from countries in Xigaze City, Tibet Autonomous Region, China. The strain is preserved in CGMCC (China General Microbiological Culture Collection Center) inOctober 23, 2019, and the microbial preservation number is CGMCC NO.18729. The lactobacillus reuteri 1723 has good tolerance and adhesiveness, can remarkably reduce body weight of rats, reduces fat accumulation in body, reduces body fat ratio, has good fermentation characteristics, can be applied to fermented milk, and can also be applied to drugs, health care products or healthy food for preventing and treating obesity.
Owner:HANGZHOU WAHAHA TECH +1

Bacteroides signal molecule microecological preparation and its preparation method

InactiveCN101125151ANumber of Spontaneous Activities NoneBlood pressure noBacteria material medical ingredientsPill deliveryAcute toxicity testingCulture fluid
The present invention relates to a b.fragilis signal molecule microbial preparation, the b.fragilis bacterium are inoculated in a culture medium for anaerobic fermentation at 35 to 38 DEG C, after that, the b.fragilis bacteria concentrate is obtained by centrifugal concentration; the bacteria cell walls are broken by high pressure; further, the bacteria concentrate is treated with enzyme hydrolysis by trypsin, chymotrypsin and pepsin, and then the preparation raw powder is obtained by solvent extraction and decompression drying. The preparation raw powder is taken as the main ingredient, and other excipients are added to prepare the oral capsules, tablets, granules, oral liquor and other preparations. The b.fragilis signal molecule product of the present invention is proven to have no acute toxicity, no influence on the times of spontaneous activity, blood pressure and respiration of the animals and can not cause the allergic reactions of the animals by animal trials. The animal trials further prove that: the product has the effects of regulating blood-lipid metabolism, reducing fat accumulation and slimming; at the same time, the present invention can improve the immunity and the anti-tumor effect by adjusting the gene expression and regulating the immune functions.
Owner:SENBAIAO SCI & TECH UNIV DALIAN

Facial pack and bathing compositions based on Hwangto (Korean loess) and preparation thereof

Disclosed are a facial pack composition and a bathing composition based on loess, and methods for preparing the same. The bathing composition makes a user feel refreshed, prevents arteriosclerosis and fat accumulation in human bodies, is useful for the treatment of maturating diseases such as dermatophytosis and dermatitis and stimulates metabolism and blood circulation system of the human body. Additionally, the facial pack includes loess having a fine particle size sufficient to avoid skin irritation and thus does not adversely affect the skin even if the user uses the pack everyday. The loess is pretreated by a unique aging method and selected additives, so that the far infrared ray-emitting effect of the loess can be maximized. Therefore, it provides skin health-aid and cosmetic effects. Further, the bathing composition is an environmental-friendly composition because the loess-containing water discharged after bathing flows into a draining path, thereby purifying a contaminated river and recovering contaminated soil.
Owner:PARK JANG YONG

Hop oxidation-reaction product, preparing method thereof and use thereof

The present invention relates to a food product and food additive comprising a hop oxidation-reaction product or an extract thereof, as well as to a fat accumulation suppressing agent and a weight gain suppressing agent having it as an active ingredient.
Owner:KIRIN HOLDINGS KK

Construction method and application of diet-induced insulin resistance model

ActiveCN104705258AAvoid the problems of instability and low molding rateEliminate adverse reactionsAnimal husbandryHigh fatIn vivo
The invention discloses a construction method of a diet-induced insulin resistance model. Male Kunming mice are induced to generate insulin resistance by being fed with high fat and high glucose food and drinking fructose solutions of a certain concentration, and the insulin resistance model is obtained. The insulin resistance disease process of human beings is simulated in the method, a manufactured animal model has hyperinsulinemia, glucose and lipid metabolism disorders and other insulin resistance classical symptoms, and the method can be suitable for mechanism research of the disease and screening of relevant medicine. Model induction is carried out through the high fat and high glucose food and low-concentration fructose drinking water, the insulin resistance disease process of the human beings can be greatly simulated, result reliability is high, the bad reaction generated by chemical reagents is removed, and the problems that when the mice are only fed with food, the model is unstable, and the model construction success rate is low are solved. Energy intake is larger than consumption through feeding of the high fat and high glucose food, in-vivo energy disequilibrium is caused, and central obesity and fat accumulation are caused, and the aim of enabling an organism to generate insulin resistance is achieved.
Owner:SHAANXI NORMAL UNIV

Device and method for treating respiratory and other diseases

A method and device to prevent and cure body diseases caused by infection factors such as: bacteria, virus, fungi, parasites as well as preventing fat accumulation in body blood vessels, lowering blood pressure, lowering cholesterol level in the blood and destroying body organs cancer cells is done by inhaling vapors of fresh crushed or sliced garlic or vapors of synthetic allicin.
Owner:HIRSHBERG ISRAEL

Therapeutic agent for treatment of diabetes

The present invention provides a therapeutic agent for treatment of diabetes and hyperlipemia, especially a therapeutic agent for treatment of type II diabetes mellitus, which comprises as the active ingredient a neurotrophic factor such as BDNF (brain-derived neurotrophic factor), ligands of trkB or trkC receptors, NGF, NT-3, NT-4 / 5, CNTF, GDNF, HGF, etc. Different from conventional oral hypoglycemic agents being mainly used in the treatment of type II diabetes mellitus, the agent of the present invention exhibit blood lipid regulating effects and body fat accumulation regulating effects, in addition to the blood glucose regulating effects. Thus, the agent of the present invention are novel, and can reduce the risk factors in diabetes accompanied by hyperlipemia or obesity, without using any other agent.
Owner:SUMITOMO DAINIPPON PHARMA CO LTD

Natural plants extract, preparation method and application thereof

The invention provides a natural plant extract, a preparation method and the application. The invention is characterized in that: the natural plant extract is prepared by grape skin, haw apple, lotus leaf, medlar, sea buckthorn, fiveleaf gynostemma herb, pilose asiabell root, radix polygoni multiflori preparata and other materials, and the materials are processed solvent extract, machining and refining and then the natural plant extract is obtained; the preparation method comprises A individual extraction method and B mixed extraction method. The natural plant extract has the advantages of effectively controlling energy absorbing of bodies, reducing fat accumulation in vivo and reducing harm of overnutrition to bodies, reducing blood fat, purifying blood, controlling blood sugar, interdicting and reversing the development of sub-healthy state, reducing morbidity risk of hyperlipemia, hypertension, diabetes, coronary heart disease, fatness, fatty liver and other diseases, providing healthy population for eating to keep fit, also providing sub-healthy population for eating to effectively interdict and reverse the development of sub-healthy state, still being used to prepare the medicament for curing hypertension, hyperlipemia, diabetes and other diseases after deep processing.
Owner:南京万舜源生物科技有限公司

Anti-myostatin antibodies, polypeptides containing variant Fc regions, and methods of use

The disclosure provides anti-myostatin antibodies and methods of making and using the same. Nucleic acids encoding the anti-myostatin antibodies and host cells comprising the nucleic acids are also provided. The anti-myostatin antibodies have uses that include treating a muscle wasting disease, reducing body fat accumulation, and increasing mass and strength of muscle tissue. The disclosure also provides polypeptides containing a variant Fc region and methods of making and using the same. Nucleic acids encoding the polypeptides and host cells comprising the nucleic acids are also provided. The polypeptides have uses that include suppressing the activation of immune cells; treating an immunological inflammatory disease, autoimmune disease, or viral infection; and increasing muscle mass and strength or reducing body fat accumulation.
Owner:CHUGAI PHARMA CO LTD
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