353 results about "Fat accumulation" patented technology

The invention provides compositions comprising an effective amount of an agent that inhibits a BET protein (e.g., Brd2, Brd3, Brd4), and methods of using such compositions for treating or preventing metabolic syndrome, obesity, type II diabetes, insulin resistance, and related disorders characterized by undesirable alterations in metabolism or fat accumulation.

The invention relates to soluble dietary fiber fruit and vegetable meal replacement powder and a preparation method thereof, in particular to dietary fiber fruit and vegetable meal replacement powder capable of adjusting in-vivo nutrient balance and inhibiting in-vivo fat accumulation and a preparation method, and belongs to the technical field of nutrition and health-care food. The dietary fiber fruit and vegetable meal replacement powder is characterized by consisting of the following components in percentage by weight: 10 to 60 percent of refined konjac powder, 15 to 50 percent of soybean dietary fiber powder, 5 to 15 percent of polydextrose, 10 to 20 percent of coix seed powder, 10 to 20 percent of yam powder, 0 to 2 percent of seasoning, and 0 to 5 percent of vitamin B. The soluble dietary fiber fruit and vegetable meal replacement powder prepared by the method is fine and smooth in mouthfeel, good in brew-up performance and rich in nutrition, and has multiple health-care effects of clearing intestines and stomach, reducing three highs, preventing obesity, whitening and moistening skin and the like.

The present invention relates to a muscular strength enhancing agent produced from fruits, and provides a strength enhancing agent or a body-fat regulating agent, derived from natural products, that may enhance muscle strength, decrease body fat or suppress body-fat accumulation without decreasing the amount of skeletal muscle or the weight of viscus; more specifically, a polyphenol produced from fruits is used to provide muscular strength enhancing agents or body-fat regulating agents, foods/beverages and pharmaceuticals that may enhance muscular strength, decrease body fat or suppress body-fat accumulation. Strength enhancing agents or body-fat regulating agents effective to enhance muscular strength, of which active component being a polyphenol derived from fruits, and foods/beverages and pharmaceuticals containing them.

The present invention provides a therapeutic agent for treatment of diabetes and hyperlipemia, especially a therapeutic agent for treatment of type II diabetes mellitus, which comprises as the active ingredient a neurotrophic factor such as BDNF (brain-derived neurotrophic factor), ligands of trkB or trkC receptors, NGF, NT-3, NT-4/5, CNTF, GDNF, HGF, etc. Different from conventional oral hypoglycemic agents being mainly used in the treatment of type II diabetes mellitus, the agent of the present invention exhibit blood lipid regulating effects and body fat accumulation regulating effects, in addition to the blood glucose regulating effects. Thus, the agent of the present invention are novel, and can reduce the risk factors in diabetes accompanied by hyperlipemia or obesity, without using any other agent.

The invention discloses a method for improving biomass and oil accumulation of oleaginous microalgae Scenedesmusdimorphus by adopting a two-stage culture strategy of co-culture and nitrogen deficiency, and belongs to the technical field of microalgae bioenergy. The invention adds a certain concentration of organic carbon source glucose to the autotrophic culture medium, and carries out concurrent culture with CO2 as the autotrophic carbon source. At the same time, under nitrogen-enriched conditions, after high-density culture of microalgae to a stable stage, the algae liquid is transferred to a nitrogen-deficient medium to continue the culture. When the glucose concentration is 1.2-5.4g/L, the initial pH is 7, and the culture time is 14-16 days, the biomass of microalgae can reach up to 4.5g/L, which is 2.57 times the biomass under autotrophic conditions; nitrogen deficiency Under these conditions, the total lipid content of microalgae reaches the highest of 29.62%, which is 1.6 times that of the nitrogen-enriched stage. By adding organic carbon sources and providing nitrogen-deficient conditions for two-stage culture, the biomass of microalgae can be effectively increased and oil accumulation can be promoted, which is of great significance to the research of large-scale production of bioenergy by microalgae.

The present invention discloses a Chinese herbal feed additive for weight increase and beef quality improvement at a late beef cattle fattening stage. The Chinese herbal feed additive comprises the following traditional Chinese medicines, by weight, 25-35 parts of pine needle powder, 5-15 parts of hawthorn, 5-15 parts of medicated leaven, 5-15 parts of swordlike atractylodes rhizome, 5-15 parts of cultivated purple perilla fruit, 3-7 parts of cyrtomium rhizome, 15-25 parts of glossy privet fruit, and 3-7 parts of licorice root. According to the present invention, various components are crushed, screened through a 60 mesh sieve, and sub-packaged according to 150 g/bag to provide a spare use, wherein the time of slaughter of beef cattle is the late fattening stage, and per beef cattle is fed with 150 g of the Chinese herbal feed additive per day; and with the Chinese herbal feed additive, the cattle can have characteristics of plump beef and fat accumulation at the late beef cattle fattening stage so as to increase beef cattle body weight, improve beef quality, and increase benefits.

The invention discloses a method for open-type culture of microalgae, which comprises the following contents: CO2 is supplied into an illumination open-type bioreactor which contains microalgae and a microalga culture medium for the growth of microalgae, wherein the CO2 is supplied by a method which is to mix a CO2-containing gas with a liquid phase by using a gas-liquid mixed conveying device, perform gas-liquid separation in a gas-liquid separator, and deliver a CO2-dissolving liquid phase obtained after gas-liquid separation to the illumination open-type bioreactor to supply the CO2 required by the growth of the microalgae. Compared with the prior method, the method solves the problem of low CO2 utilization rate caused by thinness of a liquid layer in the conventional open-type microalga culture system, improves the fat accumulation capacity in a microalga culture process, improves CO2 utilization rate and simplifies a culture device.

Provided is an oil/fat composition comprising 10.1 to 94.9 wt. % of a triglyceride, 0.1 to 30 wt. % of a monoglyceride and 5 to 59.9 wt. % of a diglyceride which has, as a fatty acid constituent thereof, 15 to 90 wt. % of an ω3-unsaturated fatty acid having less than 20 carbon atoms. The oil/fat composition of the present invention has excellent heat stability, has body-fat-accumulation resisting action, visceral-fat-accumulation resisting action, blood-sugar-level lowering action, insulin resistance improving action and leptin lowering action and is useful for, as well as pharmaceuticals, preventive or remedial food for diabetes or obesity, and feed.

The present invention aims to provide a pastry moon cake and a preparation method thereof. The preparation method includes water-oiled dough production, pastry production, a pastry filling process, filling production, raw cake production and a baking process, wherein warm water is used in the production of water-oiled dough, and the temperature of the warm water is controlled at 40-80 DEG C, and green tea powder is added in the production process of fillings. Beneficial effects of the pastry moon cake: grease contents and sugar contents in moon cakes are reduced by using vegetable oil instead of traditional animal oil and using xylitol instead of sucrose in the moon cake production process, so that the pastry moon cake can inhibit the increase of blood sugar and fat accumulation in the human body, and is suitable for diabetics and the elderly to eat; and the introduction of green tea powder into the traditional five-kernel fillings makes the pastry moon cake light in taste and delicate in fragrance, healthy and nutritional.

The invention discloses a sea cucumber saponin, a preparation method thereof and the application thereof in food or medicines. A sea cucumber saponin mixture comprises multiple sea cucumber alkyl-type triterpenoid saponins. Preferentially, the sea cucumber saponin mixture comprises holothurin A and/or echinoside A. The sea cucumber saponin mixture can also comprise one or more in holothurin A, holothurin B, echinoside A, echinoside B, 24-dehydroechinoside A and stichoposide E. The sea cucumber saponin can be applied to preparing weight-losing food or medicines, and animal experimental resultsshow that the sea cucumber saponin can be used for remarkably inhibiting weight increment and reducing internal fat accumulation so as to realize a good weight-losing effect. The preparation method of the sea cucumber saponin is low in cost, simpler in steps and less in the pollution of organic solvents on the environment; and through animal experiments, the prepared sea cucumber saponin is proved to have a good weight-losing effect so as to be used for developing safe and effective weight-losing food or medicines.

The invention discloses a method for high-efficiency culture of microalgae, which comprises the following contents: introducing a gas containing CO2 into an illumination airlift bioreactor which contains microalgae and a microalga culture medium to realize airlift, supplying CO2 and resolving O2, wherein the gas containing CO2 is from tail gas of microorganism fermentation, and the tail gas is introduced into the illumination airlift bioreactor after passing through a conveying pretreatment device. Compared with the prior art, the method disclosed by the invention has the advantages of improving the fat accumulation capacity of the microalgae in a microalga culture process, improving utilization rate of CO2, improving O2 resolution capacity, simplifying the culture device and the like.

The invention relates to lactobacillus plantarum Lp90, and a screening method and application thereof, in particular to lactobacillus plantarum with a function of inhibiting fat accumulation. The lactobacillus plantarum is named Lp90 and is preserved in the common microbiology center of the Chinese microbial strain preservation management committee, and the preservation number is CGMCC No.10453. The lactobacillus plantarum is obtained through an in-vitro nematode screening model, the fat accumulation of nematode can be reduced by 60 percent, and the lactobacillus plantarum has a potential function of preventing obesity and can be added into food, health care products or medicines as probiotics. Meanwhile, the invention provides the screening method namely a nematode culture model, and fat accumulation data of the nematode can be qualitatively and quantitatively detected, so that strains with the function of inhibiting the fat accumulation can be conveniently and quickly screened, the accuracy rate is high, and the economic cost is lower.

The invention relates to the field of microorganisms and discloses lactobacillus reuteri with a weight reducing function and an application of the lactobacillus reuteri. The lactobacillus reuteri 1723strain is separated from butter collected from countries in Xigaze City, Tibet Autonomous Region, China. The strain is preserved in CGMCC (China General Microbiological Culture Collection Center) inOctober 23, 2019, and the microbial preservation number is CGMCC NO.18729. The lactobacillus reuteri 1723 has good tolerance and adhesiveness, can remarkably reduce body weight of rats, reduces fat accumulation in body, reduces body fat ratio, has good fermentation characteristics, can be applied to fermented milk, and can also be applied to drugs, health care products or healthy food for preventing and treating obesity.

The present invention relates to a b.fragilis signal molecule microbial preparation, the b.fragilis bacterium are inoculated in a culture medium for anaerobic fermentation at 35 to 38 DEG C, after that, the b.fragilis bacteria concentrate is obtained by centrifugal concentration; the bacteria cell walls are broken by high pressure; further, the bacteria concentrate is treated with enzyme hydrolysis by trypsin, chymotrypsin and pepsin, and then the preparation raw powder is obtained by solvent extraction and decompression drying. The preparation raw powder is taken as the main ingredient, and other excipients are added to prepare the oral capsules, tablets, granules, oral liquor and other preparations. The b.fragilis signal molecule product of the present invention is proven to have no acute toxicity, no influence on the times of spontaneous activity, blood pressure and respiration of the animals and can not cause the allergic reactions of the animals by animal trials. The animal trials further prove that: the product has the effects of regulating blood-lipid metabolism, reducing fat accumulation and slimming; at the same time, the present invention can improve the immunity and the anti-tumor effect by adjusting the gene expression and regulating the immune functions.

The invention discloses a construction method of a diet-induced insulin resistance model. Male Kunming mice are induced to generate insulin resistance by being fed with high fat and high glucose food and drinking fructose solutions of a certain concentration, and the insulin resistance model is obtained. The insulin resistance disease process of human beings is simulated in the method, a manufactured animal model has hyperinsulinemia, glucose and lipid metabolism disorders and other insulin resistance classical symptoms, and the method can be suitable for mechanism research of the disease and screening of relevant medicine. Model induction is carried out through the high fat and high glucose food and low-concentration fructose drinking water, the insulin resistance disease process of the human beings can be greatly simulated, result reliability is high, the bad reaction generated by chemical reagents is removed, and the problems that when the mice are only fed with food, the model is unstable, and the model construction success rate is low are solved. Energy intake is larger than consumption through feeding of the high fat and high glucose food, in-vivo energy disequilibrium is caused, and central obesity and fat accumulation are caused, and the aim of enabling an organism to generate insulin resistance is achieved.