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67 results about "Alcoholic hepatitis" patented technology

Inflammation of the liver caused by chronic heavy drinking of alcohol.

Prevention and treatment of inflammatory conditions

ActiveUS20140187504A1Rapid recruitmentSuppresses in vitro proliferationBiocidePeptide/protein ingredientsAlcoholic cirrhosisTazarotene
The present embodiments relate to methods for the prevention and treatment of inflammatory conditions such as alcoholic liver disease (ALD). More specifically the present embodiments relate to the prevention and treatment of ALD through the administration of an Retinoic Acid Receptor (RAR) agonist. Some embodiments relate to use of tazarotene in the prevention and treatment of alcohol-induced liver injury, alcohol-related liver disease, fatty liver disease, hepatic steatosis, alcoholic hepatitis or alcoholic cirrhosis.
Owner:GRI BIO INC

Composition and method for treating nonalcoholic steatohepatitis

Nonalcoholic steatohepatitis (NASH) is a disease of the liver characterized by inflammation and damage to the liver cells. Typically, steatohepatitis involves inflammation of the liver related to fat accumulation, and mimics alcoholic hepatitis but is observed in patients who seldom or never consume alcohol. Nonalcoholic steatohepatitis can lead to serious liver damage, and ultimately cirrhosis. The present invention provides methods and compositions useful for the treatment or alleviation of nonalcoholic steatohepatitis and the pharmaceutical formulations for their administration to a human. Specifically, compositions comprised of lecithin, antioxidants and vitamin B complex are administered parenterally, most preferably by oral administration. Specific therapeutic formulations include admixtures of these compounds and specific dosage formulations include daily oral administrations of these compounds in tablet or powder forms.
Owner:VIVA AMERICA MARKETING

Chinese medicine agent for treating alcohol fatty liver and preparing method thereof

The invention relates to a Chinese herbal preparation for treating alcoholic fatty liver and the preparation method. The Chinese herbal preparation contains Astragalus root, Barbary Wolfberry Fruit, Largehead Atractylodes Rhizome, Pericarpium Citri Reticulatae Viride, Lobed Kudzuvine Root, Chicken's Gizzard-membrane (prepared), rose and Radix Rhapontici seu Radix Echinopsis. When the Chinese herbal preparation is prepared, the methods such as vapor distilment, water decoction and ethanol extraction are adopted for different ingredients for reaching the purpose of fully developing the efficacy of the drugs. The invention has the effects of replenishing qi and liver, detoxifying and descending turbid, eliminating blood stasis and freeing channels and applied for treating alcoholic fatty liver, alcoholic hepatitis and alcoholic hepatocirrhosis (liver energy deficiency, alcoholic impairment of liver, haemostasis and turbid lipid blocked in liver collaterals); the symptoms are embodied in flank ribs expansion and smothering, secret anguish, accidie and hypodynamia, intolerant fatigue, lassitude, easy fear and restiness, anorexia, tongue coating darkness, white fur and small and wiry pulse. The invention is a safe and reliable good medicine which has the advantages of prescription basing on the Chinese medical theory, sufficient drug source, simple process and evident effect.
Owner:孙蓉

Applications of lectuce tea total glycosides and method of preparing the same

InactiveCN101254222AThe adsorption purification cycle savesAvoid fat removalSugar derivativesDigestive systemAlanine aminotransferaseAlcoholic hepatitis
The invention relates to the application of Ilex latifolia total glycosides and a preparation method thereof. Studies finds that the Ilex latifolia total glycosides can reduce the content of malonaldehyde (MDA) and triglyceride (TG) in liver, increase the content of reduced glutathione (GSH) in each dose group of liver, reduce the content of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in liver, and has alcoholic hepatitis and fatty liver resisting activity. Compared with the prior art, the invention provides a new application of Ilex latifolia total glycosides in preparing drugs and / or functional food for preventing and / or treating alcoholic hepatitis and fatty liver; the invention also provides a preparation method of the Ilex latifolia total glycosides with the advantages of safe and simple process, saved cost, high efficiency, and easy quality control; and the invention further provides a preparation of the Ilex latifolia total glycosides.
Owner:海南阿苷饮品有限公司

Use of ilexlutifolia thumb total glycosides and preparation method thereof

InactiveCN101361766AThe adsorption purification cycle savesAvoid fat removalDigestive systemSolution deliveryFatty liverLiver tissue
The invention relates to an application of broadleaf holly leaf glycosides and a preparation method thereof. Researches show that the broadleaf holly leaf glycosides can lower level of malondialdehyde (MDA) and triglyceride (TG) in liver tissues, increase level of reduced glutathione(GSH) of each dosage group in liver tissues, lower level of Alanine Aminotransferase (ALT) and Aspertate Aminotransferase (AST) in liver tissues; the broadleaf holly leaf glycosides has the activity of anti-alcoholic hepatitis and anti-adiposis hepatica. Compared with the prior art, the invention has the advantages of: 1. providing a new application of broadleaf holly leaf glycosides, in particular to an application on preparing medicines for curing adiposis hepatica and alcoholic hepatitis; 2. providing a preparation method for broadleaf holly leaf glycosides, and the preparation method is safe in production technics, economic in cost, high in efficacy, easy for quality control and more simple in preparation; and 3. providing a preparation of broadleaf holly leaf glycosides.
Owner:贺震旦

Pharmaceutical composition for treating alcoholic liver diseases as well as preparation method and application of pharmaceutical composition

The invention provides a pharmaceutical composition for treating alcoholic liver diseases. The pharmaceutical composition is prepared from the following raw materials in parts by weight: 172-258 parts of flower of kudzuvine, 128.8-193.2 parts of root of codonopsis pilosula, 85.6-128.4 parts of bighead atractylodes rhizome, 85.6-128.4 parts of poria cocos, 85.6-128.4 parts of bupleurum, 128.8-193.2 parts of white peony root, 128.8-193.2 parts of salviae miltiorrhizae, 128.8-193.2 parts of polygonum cuspidatum, 128.8-193.2 parts of rhizoma alismatis, 128.8-193.2 parts of hawthorn fruit, 128.8-193.2 parts of penthorum chinense pursh, 128.8-193.2 parts of hovenia dulcis thumb and 43.2-64.8 parts of liquorice. The invention also provides a preparation method and application of the pharmaceutical composition. The pharmaceutical composition disclosed by the invention is used for treating the diseases caused by alcoholic abuse and dependency, such as mild alcoholic injury, alcoholic fatty liver and alcoholic hepatitis, has good effects of dispelling the effects of alcohol, protecting the liver and lowering lipid and is obvious in curative effect of treating the alcoholic liver diseases. In addition, the medicine can obviously shorten the alcohol effect dispelling time by about 2 hours and is stable and reliable in drug effect and convenient to carry and take, and a novel selection is provided for clinical application.
Owner:泸州医学院附属中医医院

Medicinal composition of astragalus, salvia miltrorrhiza and oxymatrine, and its preparing method

The present invention discloses a new medicine composition for curing hepatic diseases and its preparation method. It is formed from (by weight portion) 400-10000 portions of astragalus root, 200-6000 portions of salvia root and 10-200 portions of kurarinone, and also can be made up by using 2-200 portions of astragalus total saponin or astragalus polysaccharide, 2-200 portions of salvia total phenolic acid and 10-200 portions of kurarinone. Said medicine composition can be made into various dosage forms of oral preparation, injection and others. Said medicine composition can be used for curing diseases of viral hepatitis, medicamentous liver lesion, fatty liver and alcoholic hepatitis, etc.
Owner:海安江理工技术转移中心有限公司

Isodon lophanthoides extract and its prepn process and application

The present invention provides one kind of Isodon lophanthoides extract. The Isodon lophanthoides extract is prepared through crushing Isodon lophanthoides to powder finer than 10 mesh, adding water of over 3 times, extracting at 10-60 MPa pressure and concentrating. The extract may be used in preparing various clinically acceptable orally taken preparations for treating hepatitis B, immunologic hepatitis, alcoholic hepatitis and hepatic fibrosis. The extracting process with ultrafine grinding and high pressure extracting has high extracting rate of the effective components in Isodon lophanthoides, so that the extract has high treating effect.
Owner:GUANGZHOU UNIVERSITY OF CHINESE MEDICINE

Medical application of small molecule peptide of black food in liver damage repair

The invention provides medical application of small molecule peptide of black food in liver damage repair. Methionine is obtained by fermentation of an AtD-SAT transgenic yeast strain; the small molecule peptide of the black food has good anti-inflammatory and repairing effects on damaged liver cells caused by liver fibrosis and alcoholic hepatitis; drugs prepared from the small molecule peptide of the black food have the advantages of remarkable clinical effect and few toxic and side effects; a preparation method of the small molecule peptide of the black food is simple and practical.
Owner:JILIN UNIV +1

Application of compound HUBIN-1 in preparation of drug for preventing and/or treating liver inflammatory diseases

The invention relates to the field of drug research and development and particularly discloses an application of a compound HUBIN-1 in preparation of a drug for preventing and / or treating liver inflammatory diseases. Extensive and deep research discovers the hepatocyte protection function and the anti-inflammatory treatment function of the compound HUBIN-1 for the first time, the compound HUBIN-1 is applicable to various types of liver inflammations, and the application field of the compound HUBIN-1 is broadened. The novel drug for preventing and / or treating various liver inflammatory diseases such as acute hepatitis, chronic hepatitis and severe hepatitis (hepatic failure) which include viral hepatitis, drug-induced hepatitis, nonalcoholic fatty liver disease, alcoholic hepatitis, autoimmune hepatitis and the like is provided and has remarkable social benefits.
Owner:ZHEJIANG UNIV

Novel compositions and methods useful for treating or preventing liver diseases or disorders, and promoting weight loss

ActiveUS20170232027A1Reduces fat-induced obesityGood for weight lossOrganic active ingredientsDigestive systemToxic liver diseaseHepatic fibrosis
The invention includes a method of preventing or treating a toxic liver disease or disorder, such as but not limited to non-alcoholic steatohepatitis (NASH), liver injury associated with or caused by alcohol consumption in a mammal afflicted with NASH, alcoholic hepatitis, drug induced liver injury, primary sclerosing cholangitis, viral hepatitis, liver fibrosis, liver cirrhosis, and other toxic liver conditions, in a subject, such as a mammal. The invention also includes a method of promoting weight loss in a subject, such as a mammal. The invention comprises administering to the subject a therapeutically effective dose of at least one cardiac glycoside or a solvate, salt, prodrug or derivative thereof.
Owner:YALE UNIV

Pharmaceutical composition for treating or preventing alcoholic liver diseases, containing cilostazol as active ingredient

Provided is a pharmaceutical composition for the treatment and prevention of alcoholic liver diseases, including cilostazol as an active ingredient. Cilostazol inhibits expression levels of TNF-α and FAS (fatty acid synthase) gene in a concentration-dependent manner, and also significantly inhibits the activity of caspase-3. Accordingly, cilostazol shows superior effects for the treatment or prevention of alcoholic liver diseases, in particular, alcoholic hepatitis compared to pentoxifylline which is conventionally used as a therapeutic agent for the treatment for alcoholic hepatitis. Thus, cilostazol is suitable for use as a drug for the treatment or prevention of alcoholic hepatitis.
Owner:RES COOPERATION FOUND OF YEUNGNAM UNIV

Application of traditional Chinese medicine composition in preparation of medicine for treating alcoholic hepatitis

ActiveCN102657838AOvercome the disadvantages of not being suitable for modern dosage formsDigestive systemPlant ingredientsClinical efficacyLagotis brevituba
The invention provides an application of a traditional Chinese medicine composition in preparation of a medicine for treating alcoholic hepatitis. The traditional Chinese medicine composition is prepared by traditional Chinese medicines such as Tibetan caragana, phyllanthus emblica, lagotis brevituba, sandalwood padauk, swertia chirata, medicine terminalia fruit, seabuckthorn paste and rhubarb. Clinical experiments show that the traditional Chinese medicine composition has significant clinical curative effects on the alcoholic hepatitis.
Owner:SHANDONG JINHE DRUG RES DEV

Preparation method of sugar-free black rice wine

PendingCN109294807AAddresses nutrient deficienciesAvoid missingAlcoholic beverage preparationHuskDistillation
The invention discloses a preparation method of sugar-free black rice wine. The preparation method sequentially includes steps: 1, preparing melanin liquid: cleaning black rice bran husk, soaking, extracting, vacuum concentrating, filtering at low temperature, and storing for standby use; S2, preparing a wine cleaning and soaking raw materials, steaming, cooling, adding distiller's yeast, saccharifying for fermentation, and distilling; S3, adding standby concentrated melanin liquid into wine liquid obtained by distillation according a certain proportion, and stirring sufficiently to enable the wine liquid to be fully mixed with the melanin liquid; S4, filtering: filtering wine liquid after being mixed; S5, cellaring: putting the wine liquid after being filtered in a constant-temperature cellar for storage; S6, filling, sealing, boxing, and testing qualification according to specified product standards before leaving factories. The black rice wine obtained by the method has stronghealthcare function, can realize medicinal-edible effect after being drunk and has good treatment effect on alcoholic hepatitis.
Owner:湖南氿芝霖生物科技股份有限公司

Tea capable of nourishing the liver and relieving sore-throat, and preparation method thereof

The invention provides a tea capable of nourishing the liver and relieving sore-throat. The tea capable of nourishing the liver and relieving sore-throat is prepared from the following raw materials in parts by weight: 12-18 parts of herba rabdosiae, 6-10 parts of ficus carica, 5-10 parts of ampelopsis grossedentata leaf, 4-8 parts of herba portulacae, 3-6 parts of emblic leafflower fruit, 3-6 parts of flos lonicerae, 4-8 parts of radix platycodi, 4-8 parts of flos chrysanthemi and 4-7 parts of honey. The invention also provides a preparation method for the tea capable of nourishing the liver and relieving sore-throat. The raw materials of the tea capable of nourishing the liver and relieving sore-throat are from homologous plants, and all raw materials are mutually cooperated and perform a synergistic effect to realize antisepsis and anti-inflammation, improve human immunity and improve a liver metabolic function. The tea can be drunk for a long time, does not have toxic or side effects, and is suitable for crowds who always suffer from various diseases including pharyngitis, bronchitis, upper respiratory tract infection, alcoholic hepatitis, fatty liver and the like to be subjected to daily health care treatment and drinking. The preparation method for the tea capable of nourishing the liver and relieving sore-throat has the advantages of simpleness and easiness in operation and is suitable for mass production.
Owner:广东说养自然医学技术有限公司

Application of steroid saponin compound in medicinal materials of trillium or paris polyphylla to preparation of liver protection medicine

The invention relates to application of a steroid saponin compound in medicinal materials of trillium or paris polyphylla to preparation of a liver protection medicine. The prepared steroid saponin compound in the medicinal materials of trillium or paris polyphylla is one or more of pennogenin-3-0-alpha-L-rhamnopy ranosyl group(1 to 2)-beta-D-glucoside (namely polyphyllin VI), pennogenin-3-0-alpha-L-rhamnopy ranosyl group(1 to 4)-[alpha-L-rhamnopy ranosyl group(1 to 2)]-beta-D-glucoside and pennogenin-3-0-alpha-L-rhamnopy ranosyl group(1 to 4)-alpha-L-rhamnopy ranosyl group(1 to 4)-[alpha-L-rhamnopy ranosyl group(1 to 2)]-beta-D-glucoside (namely polyphyllin VII), and as the common structure units like the pennogenin-3-0-alpha-L-rhamnopy ranosyl group(1 to 2)-beta-D-glucoside (namely polyphyllin VI) are owned, the steroid saponin compound in the medicinal materials of trillium or paris polyphylla has remarkable effects of treating any hepatitis or liver injury in alcoholic hepatitis or liver injury, nonalcoholic hepatitis or liver injury, alcoholic fatty liver, non-alcoholic fatty liver, hepatic fibrosis or liver cirrhosis.
Owner:张忠立

Composition of Chinese traditional medicine for treating alcoholic hepatitis, and preparation method

A Chinese medicine for treating alcoholic hepatitis is prepared from 12 Chinese-medicinal materials including red sage root, rhubarb, fleece flower root, astragalus root, etc. Its preparing process is also disclosed.
Owner:刘铁军

Liver-protecting and alcohol-removing Chinese herbal medicine preparation

InactiveCN103479946AAchieve healingTo achieve the effect of hangover and liver protectionDigestive systemPlant ingredientsAlcoholThirst
The invention provides a liver-protecting and alcohol-removing Chinese herbal medicine preparation for treating alcoholic hepatitis caused by alcoholic poisoning. The Chinese herbal medicine preparation is prepared from the following raw materials in parts by weight: 11-15 parts of pueraria flowers, 5-7 parts of fructus amomi, 5-7 parts of amomum cardamomum, 10-14 parts of rhizoma alismatis, 8-12 parts of white atractylodes rhizome, 13-17 parts of poria cocos and 11-15 parts of grifola. The Chinese herbal medicine preparation is a pure Chinese herbal medicine preparation; the pueraria flowers are adopted for removing alcohol, quenching thirst and removing alcohol poison; the fructus amomi and the amomum cardamomum are adopted for promoting vital energy to relieve pain, warming stomach to stop diarrhea and resolving dampness to remove lumps; the rhizoma alismatis, the white atractylodes rhizome, the poria cocos and the grifola are adopted for clearing damp, promoting diuresis, tonifying spleen, benefiting vital energy, strengthening exterior, reducing sweat and calming nerves; all the raw materials are combined for protecting liver, removing alcohol and treating the alcoholic hepatitis.
Owner:衡爱萍

Medicine used for treating decompensated liver cirrhosis, and preparation method thereof

The invention relates to a medicine used for treating decompensated liver cirrhosis, and a preparation method thereof. Currently, decompensated liver cirrhosis is treated by liver protection, human plasma albumin and diuretic intravenous supplement, repeated ascites paracentesis, and the like. The treatment course is long, and treatment effect is poor. The medicine provided by the invention comprises: Mongolian milkvetch root, largehead atractylodes rhizome, swordlike atractylodes rhizome, agaric, florist's chrysanthemum, Asiatic plantain seed, common yam rhizome, ginseng, stir-fried malt, stir-fried medicated leaven, salvia miltiorrhiza, radix saussureae, hawthorn fruit, dandelion, mix-fried scale, mix-fried turtle shell, peach seed, rhubarb, composite protein powder, lecithin vitamin E, and colostrum capsules. The medicine provided by the invention is used for treating decompensated liver cirrhosis diseases. The medicine has the functions of hard mass softening, stasis removing, spleen invigorating, and dampness removing. Through liver protection, dieresis, and nutritional immunology effect improving, ascite is discharged. The medicine has a good treatment effect against decompensated liver cirrhosis after alcoholic hepatitis or viral hepatitis.
Owner:郭丽曼 +1

Alcoholic hepatitis treatment Kazakh traditional drug composition and preparation method thereof

The present invention discloses an alcoholic hepatitis treatment Kazakh traditional drug composition and a preparation method thereof, wherein a six-element theory of the traditional medicine theory basis "Kazakh Medicine Outline" is combined, the six-element theory comprises a "a le te tu gu er theory", a "hu wa ti" theory (ie., a qi, function and energy theory), a "su le" theory (ie., a body fluid theory), a "mu xie lie er" theory (ie., an organ theory), and the like, and the composition has effects of prevention and treatment of various common colds such as viral cold, wind cold type cold and the like. The preparation method comprises: selecting the traditional and commonly used medicinal plant Rhamnus Cathartica L fruit (ie., Xinjiang drug buckthorn fruit), raw milkvetch root and radix puerariae, carrying out water extraction and ethanol extraction, and uniformly mixing to prepare an oral preparation, wherein formulations comprise an decoction, pills, powders, granules, tablets and other oral formulations suitable for clinical alcoholic hepatitis prevention and treatment. The alcoholic hepatitis treatment Kazakh traditional drug composition particularly provides a good treatment effect for alcoholic hepatitis oral adjuvant therapy, and has characteristics of reasonable formula, convenient preparation, exact treatment effect, rapid effect, no stimulation, and no other toxic-side effects.
Owner:阿斯亚·拜山伯 +1

Prevention and treatment of inflammatory conditions

The present embodiments relate to methods for the prevention and treatment of inflammatory conditions such as alcoholic liver disease (ALD). More specifically the present embodiments relate to the prevention and treatment of ALD through the administration of an Retinoic Acid Receptor (RAR) agonist. Some embodiments relate to use of tazarotene in the prevention and treatment of alcohol-induced liver injury, alcohol-related liver disease, fatty liver disease, hepatic steatosis, alcoholic hepatitis or alcoholic cirrhosis.
Owner:GRI BIO INC

Preparation method of tablet candies capable of dispelling effects of alcohol and protecting liver

The invention discloses a preparation method of tablet candies capable of dispelling the effects of alcohol and protecting the liver. The preparation method comprises the following steps of (1) preparing raw materials; (2) preparing raw material particles; (3) preparing raw material extract; (4) blending mixed powder; (5) preparing mixed particles; and (6) preparing the tablet candies. According to the preparation method of the tablet candies capable of dispelling the effects of alcohol and protecting the liver, the tablet candies have the effects of clearing away heat and toxic materials, removing jaundice, resolving dampness and protecting the liver, have a good protection effect on the liver, can reduce the damage of various substances ingested in daily life to the liver, are helpful for reducing alcoholic fatty liver, alcoholic hepatitis, alcoholic liver fibrosis, alcoholic liver cirrhosis and other diseases caused by drinking, have no side effect, and have broad application prospects and huge economic benefits.
Owner:广州存正生物科技有限公司

Novel medicine composition for treating hepatic diseases

The present invention belongs to the field of medicine technology, and is especially a kind of medicine composition and its preparation process. The medicine composition is prepared with kurarinone 4-400 weight portions, glutathione 3-300 weight portions, and tiopronin 1-100 weight portions. The medicine composition may be prepared into different pharmaceutically acceptable forms, preferably injection and oral preparation. It has the pharmacological activities of antagonizing virus, improving liver cell function, antagonizing liver fibrosis, regulating immunity, diminishing inflammation, etc. and may be used in treating various hepatic diseases, viral hepatosis, medicinal hepatosis, alcoholic hepatosis, etc.
Owner:海安江理工技术转移中心有限公司

Traditional Chinese medicine composition for the treatment of chronic liver disease and preparation method thereof

InactiveCN106109731APromote growthGastrointestinal function recoveryDigestive systemPlant ingredientsSwertia mileensisChronic hepatitis
The invention provides a traditional Chinese medicine composition for the treatment of chronic liver disease. The composition is made from the following raw materials by weight: 1 part of swertia mileensis, 0.4-0.7 part of capillary Artemisia, 0.4-0.7 part of Astragalus mongholicus, 0.3-0.6 part of herba verbenae, 0.2-0.5 part of herba taching, 0.1-0.2 part of radix bupleuri, 2-8 parts of bighead atractylodes rhizome, 10-15 parts of red ginseng, 10-13 parts of corydalis tuber, and 15-25 parts of Stephania tetrandra. The invention also provides a preparation method of the traditional Chinese medicine composition for the treatment of chronic liver disease. Compared with the prior art, the invention has the following advantages of supporting right, dispelling evil, clearing heat and draining dampness, clearing liver and gallbladder damp-heat, and purging damp fire of liver and gallbladder. The composition is used for the treatment of acute jaundice hepatitis, chronic icteric hepatitis, chronic hepatitis, liver cirrhosis, liver ascites, alcoholic hepatitis, fatty liver, hepatitis B and transaminase elevation, also can be used for the control of liver cancer.
Owner:赵玮

Liuwei Anxiao pharmaceutical composition and application of preparation thereof in preparation of drug for treating alcoholic hepatitis

The invention discloses a Liuwei Anxiao pharmaceutical composition and application of a preparation thereof in preparation of a drug for treating alcoholic hepatitis. The Liuwei Anxiao pharmaceutical composition comprises six medicine ingredients, namely, Tibet inula root, rheum officinale, rhizoma kaempferiae, fumed gypsum, fructus chebulae and tronae. The clinical test shows that the Liuwei Anxiao pharmaceutical composition can protect alcoholic liver injury and can also obviously improve AST (Aspartate Transaminase), ALT (Alanine Aminotransferase), GGT (Gamma Glutamyl Transpeptidase), TBiL (Total Bilirubin) and other biochemical indexes.
Owner:JINKE TIBETAN MEDICINE QINGHAI PROV

A kind of fat stem cell culture medium and application thereof

ActiveCN107345216BImprove the ability to resist the growth pressure of adversityGuaranteed continuous value-addedDigestive systemCulture processDiseasePost transplant
The invention provides an adipose-derived stem cell culture medium which comprises a basic culture medium and an additive, wherein the additive is one or two of lysophosphatidic acid (LPA) or sphingosine 1-phosphate (S1P). A culture medium used in a conventional adipose-derived stem cell in-vitro culture method is optimized, and compared with a conventional product, the culture medium additionally comprises the special LPA and S1P components. In-vitro tests and in-vivo tests show that the adverse environment growth capability of stem cells can be improved if LPA and S1P are independently or simultaneously used in the adipose-derived stem cell culture process, meanwhile continuous value increase of adipose-derived stem cells can be ensured, and phenotype and function stability of the adipose-derived stem cells can be maintained. By adopting the culture medium, the value increase efficiency, the phenotype stability and the security of in-vitro culture of the adipose-derived stem cells can meet levels of conventional culture systems, meanwhile the efficiency in treating acute liver injury and alcoholic hepatitis after transplanting is greatly improved, and the cultured adipose-derived stem cells can be relatively applicable to stem cell transplanting clinical treatment on multiple diseases.
Owner:JINAN UNIVERSITY

Application of Liuwei Anxiao pharmaceutical composition and its preparation in the preparation of drugs for treating alcoholic hepatitis

The invention discloses the application of Liuwei Anxiao pharmaceutical composition and its preparation in the preparation of drugs for treating alcoholic hepatitis. It is composed of six herbs such as seed and alkali flower. Clinical trials have shown that the Liuweian Xiaosan pharmaceutical composition has a protective effect on alcoholic liver injury, and can significantly improve biochemical indicators such as AST, ALT, GGT, and TBiL. <pb pnum="1" / >
Owner:JINKE TIBETAN MEDICINE QINGHAI PROV

Composition of Chinese traditional medicine for treating alcoholic hepatitis, and preparation method thereof

A Chinese medicine for treating alcoholic hepatitis is prepared from 12 Chinese-medicinal materials including red sage root, rhubarb, fleece flower root, astragalus root, etc. Its preparing process is also disclosed.
Owner:刘铁军
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