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Application of traditional Chinese medicine composition in preparation of medicine for treating alcoholic hepatitis

A technology for alcoholic hepatitis and composition, applied in the field of application of Chinese herbal medicine, can solve problems such as application of undisclosed pharmaceutical composition

Active Publication Date: 2012-09-12
SHANDONG JINHE DRUG RES DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

None of the above documents 1-5 disclose the application of the pharmaceutical composition in the preparation of drugs for the treatment of alcoholic hepatitis

Method used

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  • Application of traditional Chinese medicine composition in preparation of medicine for treating alcoholic hepatitis
  • Application of traditional Chinese medicine composition in preparation of medicine for treating alcoholic hepatitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0065] Embodiment 1 Chinese medicine composition capsule

[0066] Recipe:

[0067] Caragana 39.3g, Emlical 31.4g, Rabbit Ear Grass 23.5g, Red Sandalwood 23.5g, Indian Swertia 23.5g, Myrobalan 23.5g, Sea Buckthorn Cream 23.5g, Rhubarb 23.5g, Corydalis 23.5g , Ganqing Qinglan 23.5g, dried ginger 15.8g.

[0068] Preparation:

[0069] a) According to the composition ratio of raw materials, 6 medicinal materials including Caragana japonica, short-tube rabbit ear grass, Ganqing Qinglan, emblica, myrobalan, and rhubarb were extracted twice with water, and the amount of water added each time was the total of the 6 medicinal materials. 10 times the weight, reflux extraction, each extraction for 2 hours, filtering, combining the liquid medicine, and concentrating the liquid medicine under reduced pressure to a thick paste A with a relative density of 1.30 at 50°C;

[0070] b) According to the composition ratio of the raw materials, take 2 kinds of medicinal materials, including Indi...

Embodiment 2

[0074] Embodiment 2 Chinese medicine composition tablet

[0075] Recipe:

[0076] Caragana 39.3g, Emlical 31.4g, Rabbit Ear Grass 23.5g, Red Sandalwood 23.5g, Indian Swertia 23.5g, Myrobalan 23.5g, Sea Buckthorn Cream 23.5g, Rhubarb 23.5g, Corydalis 23.5g , Ganqing Qinglan 23.5g, dried ginger 15.8g.

[0077] Preparation:

[0078] a) According to the composition ratio of raw materials, 6 medicinal materials including Caragana japonica, short-tube rabbit ear grass, Ganqing Qinglan, emblica, myrobalan, and rhubarb were extracted by adding water once, and the amount of water added each time was the total of the 6 medicinal materials. 14 times the weight, the extraction temperature is 50°C, extract for 4 hours each time, filter, combine the liquid medicine, and concentrate the liquid medicine under reduced pressure to 50°C to a thick paste A with a relative density of 1.20;

[0079] b) According to the composition ratio of the raw materials, take 2 kinds of medicinal materials,...

Embodiment 3

[0082] Embodiment 3 Chinese medicine composition granule

[0083] Recipe:

[0084] Caragana 39.3g, Emlical 31.4g, Rabbit Ear Grass 23.5g, Red Sandalwood 23.5g, Indian Swertia 23.5g, Myrobalan 23.5g, Sea Buckthorn Cream 23.5g, Rhubarb 23.5g, Corydalis 23.5g , Ganqing Qinglan 23.5g, dried ginger 15.8g.

[0085] Preparation:

[0086] a) According to the composition ratio of raw materials, 6 medicinal materials including Tibetan Caragana, short-tube rabbit ear grass, Ganqing Qinglan, emblica, myrobalan, and rhubarb were extracted with water for 4 times, and the amount of water added each time was the total of the 6 medicinal materials. 6 times the weight, the extraction temperature is 95°C, extract for 1 hour each time, filter, combine the liquid medicine, and concentrate the liquid medicine under reduced pressure to 50°C to a thick ointment A with a relative density of 1.40;

[0087] b) According to the composition ratio of the raw materials, take 2 kinds of medicinal materia...

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Abstract

The invention provides an application of a traditional Chinese medicine composition in preparation of a medicine for treating alcoholic hepatitis. The traditional Chinese medicine composition is prepared by traditional Chinese medicines such as Tibetan caragana, phyllanthus emblica, lagotis brevituba, sandalwood padauk, swertia chirata, medicine terminalia fruit, seabuckthorn paste and rhubarb. Clinical experiments show that the traditional Chinese medicine composition has significant clinical curative effects on the alcoholic hepatitis.

Description

technical field [0001] The invention relates to the application of a traditional Chinese medicine composition in the preparation of medicines for treating alcoholic hepatitis, belonging to the field of Chinese herbal medicine applications. Background technique [0002] Alcoholic hepatitis is a liver disease caused by long-term heavy drinking. Severe alcoholism can induce extensive liver cell necrosis and even liver failure. The disease is one of the common liver diseases in our country. Seriously endanger people's health. Alcoholic hepatitis is also a clinical type of alcoholic liver disease. It is a group of clinicopathological syndromes caused by massive necrosis of liver cells in a short period of time. It can occur on the basis of liver cirrhosis with or without liver cirrhosis. The main manifestations are elevated serum ALT and AST and serum total bilirubin were significantly increased, which may be accompanied by fever and elevated neutrophils in peripheral blood. S...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P1/16
Inventor 马振元邵成雷王海平单玉刚郑亭亭
Owner SHANDONG JINHE DRUG RES DEV
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