Preparation method of traditional Tibetan medicine composition for treating liver diseases
A composition and technology of Tibetan medicine, which is applied in the field of preparation of Tibetan medicine composition, can solve the problems of slow release of active ingredients of raw materials, affecting the absorption and utilization of active ingredients of medicines, etc., to protect thermally unstable ingredients, realize effective enrichment, The effect of increasing the dosing concentration
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Embodiment 1-5
[0038] The proportions by weight of the raw materials of the pharmaceutical compositions of Examples 1-5 are as follows:
[0039] Turquoise 17.6 parts, Tianzhu yellow 17.6 parts, Safflower 43.7 parts, Saffron 7 parts, Meconopsis 52 parts, Ganqingqinglan 35 parts, Saibei Corydalis 35 parts, Yanjing cream 38.2 parts, Clove 17.6 parts, artificial bezoar 3.5 parts, 17.6 parts of Indian swallow, 10.5 parts of coriand melon seeds, 3.5 parts of stone flower, 1.4 parts of artificial musk.
[0040] The original commercially available Ganchang Capsule used for comparison was a product of Jinhe Tibetan Medicine Co., Ltd.
experiment example 1
[0041] The Ganchang pharmaceutical composition used in Experimental Example 1 is the pharmaceutical composition prepared in Examples 1-5.
[0042] The DM130 resin used in the embodiments and experimental examples is available from Anhui Samsung Resin Technology Co., Ltd.; HPD600 and YWD-01 resins are available from Cangzhou Baoen Chemical Co., Ltd.; X-5, NKA, ADS-F8, LS-300 , D101 type resin is available at Nankai University Chemical Plant; LSA-21LSA-40 type resin is available at Xi'an Lanxiao Technology Co., Ltd.
Embodiment 1
[0043] Example 1. Preparation of a pharmaceutical composition capsule for treating liver disease
[0044] (1) Take cloves according to the composition ratio of the raw materials, add 6 times the weight of water, and use steam distillation to extract the volatile oil for 4 hours, collect the volatile oil, obtain the volatile oil, filter the drug solution, and obtain the extract A'and the drug residue A;
[0045] Add the collected volatile oil into a 4% by weight percent β-cyclodextrin saturated aqueous solution. The volume-weight ratio of volatile oil to β-cyclodextrin is 1ml:4g. Under stirring conditions, keep the temperature at 50°C and stir for 4h, -4°C Refrigeration overnight, suction filtration, precipitation, vacuum drying at 5°C to obtain volatile oil inclusion compound;
[0046] (2) According to the composition and ratio of the raw materials, take the 7 medicinal materials, including Qinglan, Safflower, Meconopsis, Corydalis, Swallow Swallow, Swallow Seed, Stone Flower, and mi...
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