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Preparation method of traditional Tibetan medicine composition for treating liver diseases

A composition and technology of Tibetan medicine, which is applied in the field of preparation of Tibetan medicine composition, can solve the problems of slow release of active ingredients of raw materials, affecting the absorption and utilization of active ingredients of medicines, etc., to protect thermally unstable ingredients, realize effective enrichment, The effect of increasing the dosing concentration

Active Publication Date: 2013-12-11
JINKE TIBETAN MEDICINE QINGHAI PROV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the preparation methods of Ganchang drugs in the prior art all adopt simple physical treatment of crushing and mixing the raw materials, and the active ingredients of the raw materials are released slowly, which seriously affects the absorption and utilization of the active ingredients of the drug. It is urgent to introduce modern preparation methods. Provide fast dissolution, onset of effect, and better absorption and utilization of Ganchang preparations

Method used

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  • Preparation method of traditional Tibetan medicine composition for treating liver diseases
  • Preparation method of traditional Tibetan medicine composition for treating liver diseases
  • Preparation method of traditional Tibetan medicine composition for treating liver diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-5

[0038] The proportions by weight of the raw materials of the pharmaceutical compositions of Examples 1-5 are as follows:

[0039] Turquoise 17.6 parts, Tianzhu yellow 17.6 parts, Safflower 43.7 parts, Saffron 7 parts, Meconopsis 52 parts, Ganqingqinglan 35 parts, Saibei Corydalis 35 parts, Yanjing cream 38.2 parts, Clove 17.6 parts, artificial bezoar 3.5 parts, 17.6 parts of Indian swallow, 10.5 parts of coriand melon seeds, 3.5 parts of stone flower, 1.4 parts of artificial musk.

[0040] The original commercially available Ganchang Capsule used for comparison was a product of Jinhe Tibetan Medicine Co., Ltd.

experiment example 1

[0041] The Ganchang pharmaceutical composition used in Experimental Example 1 is the pharmaceutical composition prepared in Examples 1-5.

[0042] The DM130 resin used in the embodiments and experimental examples is available from Anhui Samsung Resin Technology Co., Ltd.; HPD600 and YWD-01 resins are available from Cangzhou Baoen Chemical Co., Ltd.; X-5, NKA, ADS-F8, LS-300 , D101 type resin is available at Nankai University Chemical Plant; LSA-21LSA-40 type resin is available at Xi'an Lanxiao Technology Co., Ltd.

Embodiment 1

[0043] Example 1. Preparation of a pharmaceutical composition capsule for treating liver disease

[0044] (1) Take cloves according to the composition ratio of the raw materials, add 6 times the weight of water, and use steam distillation to extract the volatile oil for 4 hours, collect the volatile oil, obtain the volatile oil, filter the drug solution, and obtain the extract A'and the drug residue A;

[0045] Add the collected volatile oil into a 4% by weight percent β-cyclodextrin saturated aqueous solution. The volume-weight ratio of volatile oil to β-cyclodextrin is 1ml:4g. Under stirring conditions, keep the temperature at 50°C and stir for 4h, -4°C Refrigeration overnight, suction filtration, precipitation, vacuum drying at 5°C to obtain volatile oil inclusion compound;

[0046] (2) According to the composition and ratio of the raw materials, take the 7 medicinal materials, including Qinglan, Safflower, Meconopsis, Corydalis, Swallow Swallow, Swallow Seed, Stone Flower, and mi...

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PUM

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Abstract

The invention relates to a preparation method of a traditional Tibetan medicine composition for treating liver diseases, which comprises the following steps: extracting and including volatile oil, extracting with ethanol, pulverizing the medicinal materials into fine powder, forming the preparation and the like. Compared with the traditional preparation, the medicine application compliance of the patient can be obviously enhanced. The pharmaceutical preparation prepared by the method provided by the invention can implement high absorption speed, quick effect taking and high bioavailability on the premise of reserving the drug effect of the original preparation; the effective ingredient can reach to the focus position centrally; and the pharmaceutical preparation has favorable curative effect.

Description

Technical field [0001] The invention relates to a preparation method of a Tibetan medicine composition, in particular to a preparation method of a Tibetan medicine composition for treating liver diseases, and belongs to the field of Tibetan medicine preparations. Background technique [0002] The liver is the metabolic center of the human body and is one of the important organs for maintaining life. Its functional status is closely related to the health of the human body. The destruction of liver cells and the damage of liver function may cause a series of symptoms of inadaptability. Hepatitis belongs to the category of "liver disease" in traditional Chinese medicine. Liver diseases are mostly caused by feeling the poison of dampness and turbidity; or eating disorderly, damages the spleen and stomach, resulting in abnormal flow of qi in water and valleys, dampness and turbidity, internal resistance, stagnation of steam and heat to mix damp and heat, spleen and stomach Obstruction...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/48A61K36/899A61P1/16
Inventor 孙泰俊邵成雷刘玉芹李丽张本永
Owner JINKE TIBETAN MEDICINE QINGHAI PROV
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